Methods and New Tools in Mental Health Research

Gut Microbiota, Antipsychotics, and Metabolic Alterations in Children and Adolescents: Protocol for a Longitudinal Observational Study

Marcela França Dias, Ana Paula de Alcântara Freitas, Suzana Figueiredo Collares, Renata Maria Silva Santos, Yago Jean de Almeida Nogueira, Antônio Márcio de Ávila Júnior, Tamires Coelho Martins, Paulo Marcos Brasil Rocha, Marco Aurélio Romano-Silva, Débora Marques de Miranda

JMIR Res Protoc 2025 (Dec 29); 14:e77374

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ChatGPT Clinical Use in Mental Health Care: Scoping Review of Empirical Evidence

Raluca Balan, Thomas P Gumpel

JMIR Ment Health 2025 (Dec 24); 12:e81204

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Time Spent on Social Media Applications in Relation to Depressive Symptoms During Emerging Adulthood and the Mediating Role of Sleep Quality: Cross-Sectional Observational Study

Qi Zou, Jiabi Qin, Lei Zhang, Wenhua Wang, Xiaoxiao Yuan, Tingting Wang, Yuan Peng, Ye Chen, Linfei Dou, Xinghua Yang, Xirennayi Abudurexiti, Mingyang Wu

J Med Internet Res 2025 (Dec 19); 27:e75337

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Exploration of Factors That Affect Engagement With the Experience Sampling Method and Service Users’ Experience of This Within the AVATAR2 Trial: Mixed Methods Study

Sophie Dennard, Philippa Garety, Clementine Edwards, Andrew Gumley, Oliver Owrid, Lucy Miller, Stephanie Allan, Alison Duerden, Francis Yanga, Chloe Burns, Helena Fletcher, Amy Grant

JMIR Form Res 2025 (Dec 12); 9:e78204

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Observer-Independent Assessment of Content Overlap in Mental Health Questionnaires: Large Language Model–Based Study

Annkathrin Böke, Hannah Hacker, Millennia Chakraborty, Luise Baumeister-Lingens, Jasper Vöckel, Julian Koenig, David HV Vogel, Theresa Katharina Lichtenstein, Kai Vogeley, Lana Kambeitz-Ilankovic, Joseph Kambeitz

JMIR AI 2025 (Dec 11); 4:e79868

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Comparing Human and AI Therapists in Behavioral Activation for Depression: Cross-Sectional Questionnaire Study

Inka Napiwotzki, Julian Laue, Flora Caldarone, Maximilian Idahl, Uwe Hadler, Haithem Amrani, Elisabeth Hildt, Kai G Kahl, Wolfgang Nejdl

JMIR Form Res 2025 (Dec 04); 9:e78138

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The Design Rationale and Preliminary Evaluation of a Prototype Designed by People With Lived Experience of Psychosis and Professionals: Design Research Study

Lars Veldmeijer, Gijs Terlouw, Job Van 'T Veer, Jim Van Os, Nynke Boonstra

J Particip Med 2025 (Dec 04); 17:e80184

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Immersive Virtual Reality–Assisted Therapy for Distressing Voices in Psychosis: Qualitative Study of Participants’ and Therapists’ Experiences in the Challenge Trial

Mads Juul Christensen, Matilde Poulsen Rydborg, Rikke Jørgensen, Cecilie Dueholm Nielsen, Jan Mainz, Imogen H Bell, Neil Thomas, Lisa Charlotte Smith, Lise Sandvig Mariegaard, Thomas Ward, Merete Nordentoft, Louise Birkedal Glenthøj, Ditte Lammers Vernal

JMIR Serious Games 2025 (Dec 01); 13:e77920

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Initial Development of a Multidimensional Computerized Adaptive Test for Intensive Longitudinal Assessment of Suicide Risk: Development and Usability Study

Kenneth McClure, Brooke A Ammerman, Cheng Liu, Miguel Blacutt, Connor O'Brien, Ross Jacobucci

JMIR Form Res 2025 (Nov 26); 9:e76544

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Prediction of Postoperative Venous Thromboembolism in Patients With Traumatic Brain Injury: Model Development and Validation Study

Jiang Zheng, Qiling Jiang, Yusheng Zhan, Yanming Tang, Xiaohui Du, Guangrong Xiang, Yufang Ouyang, Hong Fu

JMIR Med Inform 2025 (Nov 17); 13:e78655

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Sleep and Activity Patterns as Transdiagnostic Behavioral Biomarkers in Psychiatry: Longitudinal Observational Study From the DeeP-DD Study

Dylan Hamitouche, Tihare Zamorano, Youcef Barkat, Deven Parekh, Lena Palaniyappan, Sara Jalali, David Benrimoh

JMIR Form Res 2025 (Nov 14); 9:e81107

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Using Digital Phenotypes to Identify Individuals With Alexithymia in Posttraumatic Stress Disorder: Cross-Sectional Study

Tomas Meaney, Vijay Yadav, Isaac Galatzer-Levy, Richard Bryant

JMIR Ment Health 2025 (Nov 13); 12:e83575

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Influence of Topic Familiarity and Prompt Specificity on Citation Fabrication in Mental Health Research Using Large Language Models: Experimental Study

Jake Linardon, Hannah K Jarman, Zoe McClure, Cleo Anderson, Claudia Liu, Mariel Messer

JMIR Ment Health 2025 (Nov 12); 12:e80371

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Effects of Shallow Needling for Chronic Primary Insomnia: Protocol for a Randomized Controlled Trial

Wanqing Lin, Chenlin Wang, Jiajia Ye, Yingling Ye, Min Tang, Qianqian Hu, Bin Chen

JMIR Res Protoc 2025 (Nov 11); 14:e76501

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Solution-Focused Brief Intervention for Substance Use: Protocol for a Multisite Randomized Controlled Trial

Karla González-Suitt, Alvaro Vergés, Rodrigo Portilla Huidobro, Bárbara Donoso Vargas

JMIR Res Protoc 2025 (Nov 11); 14:e75628

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Personalization Strategies for Increasing Engagement With Digital Mental Health Resources: Sequential Multiple Assignment Randomized Trial

Julien Rouvere, Isabell R Griffith Fillipo, Meghan Romanelli, Ashish Sharma, Brittany A Mosser, Theresa Nguyen, Kevin Rushton, John Marion, Tim Althoff, Michael D Pullmann

JMIR Ment Health 2025 (Nov 04); 12:e73188

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What Does Text Mining of Reddit Forums Reveal About Factors Surrounding Mental Health in Singapore?

Charles Alba, Abel Beng Heng Ang, Vahid Abbasian, Gerard Chung

J Med Internet Res 2025 (Oct 31); 27:e72959

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Barriers and Enablers to Young People’s Posting, Responding, and Reading Behaviors on Mental Health Forums Using the Behavior Change Wheel: Qualitative Study

Zhen Lim, Si Yin Lim, Siqi Lu, Leslie Morrison Gutman

JMIR Hum Factors 2025 (Oct 31); 12:e71549

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Moderating Role of State and Trait Positive Affect in Virtual Reality Exposure for Public Speaking Anxiety: Protocol for a Multisite Experimental Study

Michael W Otto, Laura J Long, Santiago Papini, Tara Culver, Charles T Taylor, Mikael Rubin, Hayley E Fitzgerald, Qimin Liu, Jasper A J Smits, Rebecca A Anderson, Asimina Aslanidou, Christoph Benke, Wouter R Cox, Iris M Engelhard, Sydney E Friedman, Rachel R Goodman, Bronwyn M Graham, Bridget A Hearon, Houston W Howard, Jolene Jacquart, Hannah M Johnson, M Alexandra Kredlow, Charlene L M Lam, Eric B Lee, Grace Vogelzang McClure, Peter M McEvoy, Christiane A Melzig, Tara M Moore, Karen Moses, Samantha M Nagy, Jill M Newby, Paul F R Pfaff, Amy Regan, Winfried Rief, Daniel Rudaizky, Logan H Smith, Sharon C Sung, Matthias J Wieser, Alex H K Wong, Quincy J J Wong, Nur Hani Zainal, Zhiqi Zhang

JMIR Res Protoc 2025 (Oct 30); 14:e80010

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A Neuroaffirmative, Self-Determination Theory–Based Psychosocial Intervention for Adults With Attention-Deficit/Hyperactivity Disorder: Randomized Feasibility Study

Rebecca Elizabeth Champ, Rita Wengorovius Meneses, Marios Adamou, Warren Gillibrand, Sally Arrey, Barry Tolchard

JMIR Form Res 2025 (Oct 29); 9:e69943

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