Depression and Mood Disorders; Suicide Prevention

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Articles published in 2026 in this theme: 227 (scroll down to load remaining articles)

2026

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Smartphone-Delivered Cognitive Behavioral Digital Therapeutic for Children and Adolescents With Major Depressive Disorder: Protocol for a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Xue Li, Li Sun, Minglong Gao, Lan Wang, Wenting Lu, Xuejiao Hou, Qingjiu Cao, Ying Qian, Xianglan Wang, Hong Wang, Jing Liu

JMIR Res Protoc 2026 (Nov 13); 15:e103430

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Effectiveness of Conversational Agents for Depression and Anxiety: Systematic Review and Network Dose-Response Meta-Analysis of Agent Types, Dose, and Human Support

Pengyu Yang, Ping Lei Chui, Mingxin He, Yao Wu, Pengfei Cheng, Minxiang Li, Haojie Sun, Lurong Cai, Hua Zhang

J Med Internet Res 2026 (Nov 13); 28:e104186

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Suicidal Ideation Endorsed on the Patient Health Questionnaire-9 at Intake and Treatment Outcomes in Gambling Disorder Care: Retrospective Cohort Study

Elizabeth Knight, Kelsey McAlister, Cynthia Grant, Landry Huffman, Jennifer Huberty

JMIR Form Res 2026 (Nov 12); 10:e106739

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Potential Impact of Breathing Practice on Brain and Mental Health in Rural Adolescents With Psychiatric Symptoms: Protocol for a Single-Arm Pilot Feasibility Trial

Pravesh Sharma, Kaylynn Imsande, Danielle Boos, Nicholas L Bormann, Rowa Osman, Marin Nycklemoe, Seokbeen Lim, Stephan Arndt, Jana Kainerstorfer, Paul H Min

JMIR Res Protoc 2026 (Nov 11); 15:e91615

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Hands pouring white pills from a bottle into an open palm.

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Depression Screening Positivity, Treatment-Seeking Intention, and Willingness to Take Antidepressants in a Self-Selected Online Sample of Korean Adults: Cross-Sectional Questionnaire Study

Ha-Na Kim, Chul-Min Kim, Young Kyu Park, Kiheon Lee, Youn Huh, Wonsuk Kim, Young Sik Kim

JMIR Form Res 2026 (Nov 11); 10:e96178

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Child holding a white smartphone, focusing on the screen.

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Adolescent and Young Adult Preferences for the Delivery of Caring Contacts and the Incorporation of AI: Qualitative Interview Study

Kenneth Yi, Patrick Wedgeworth, Denise Chang, Sarah Danzo

JMIR Form Res 2026 (Nov 11); 10:e104853

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Woman using smartphone with chatbot icon in speech bubble

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Psychosocial Correlates of AI Chatbot Use for Emotional Support Among Young Adults: Cross-Sectional Study

Tamaki Hosoda-Urban, Ben Urban

JMIR Ment Health 2026 (Nov 11); 13:e104812

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Man in sweater looking out rainy window, reflecting winter blues

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Voice-Derived Speech Features of Anhedonia in Adults With Depression: Exploratory Secondary Analysis of a Semistructured Clinical Interview

Christopher G Beevers, Olivia Brady, Kean J Hsu, Rochelle A Stewart

JMIR Form Res 2026 (Nov 10); 10:e94315

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Woman's hands typing on a laptop in a dimly lit room, symbolizing remote work productivity.

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Evidence-Based Alignment of Reddit Peer Advice for Depression and Anxiety: Qualitative Content Analysis

Yu Takizawa, Ehsan Abedin, Joanne Glover, Peivand Bastani

J Med Internet Res 2026 (Nov 04); 28:e92971

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A Large Language Model–Based System for Depression Symptom Identification: Iterative Qualitative Co-Design Studies

Abeer Alotaibi, Corina Sas, Hossein Rahmani

JMIR Form Res 2026 (Nov 03); 10:e95422

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Two people discuss CommonGround, a platform for connecting people with long-term conditions.

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Improving CommonGround, an Online Peer Support Intervention for People Living With Long-Term Physical Health Conditions and Subthreshold Depression: Theory of Change–Informed Qualitative Study

Hannah Grace Jones, Ciara Regan, Grace Lavelle, Elly Aylwin-Foster, Alan Simpson, Ewan Carr, Matthew Hotopf, Vanessa Lawrence

J Med Internet Res 2026 (Nov 03); 28:e92384

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Study Design and Lessons Learned From Using Google Takeout Donations for Suicide Prevention Research: Prospective Cohort Study

Katherine Anne Comtois, Payton Smythe, Amanda Kerbrat, Ethan H Kim, Natalie Crouch, Ava Homiar, Brittany Mosser, Nichole Sams, Michelle L Harvey, Courtney L Bagge, Trevor Cohen, Patricia A Arean

J Med Internet Res 2026 (Nov 03); 28:e83637

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Pregnant woman in bed at night using her smartphone

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The Mediating Role of Sleep Quality in Associations of Smartphone Addiction and Time-Specific Use With Prenatal Depression and Anxiety: Cross-Sectional Observational Study

Xiangxin Zhang, Mixia Ouyang, Xiaoli Wu, Xinghua Yang, Xinyi Wang, Yuxinqiao Cao, Mingmin Xu, Yanling Shu, Mingyang Wu

JMIR Mhealth Uhealth 2026 (Oct 30); 14:e100064

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Purrble Use Among LGBTQ+ Young People With Self-Harm Experiences: Findings From a Qualitative Process Evaluation of a Randomized Controlled Trial

A Jess Williams, Ellen Townsend, Lauren Posada, Seonaid Cleare, Lucy Martin, Amelia Chapman-Nisar, Chris Hollis, James J Gross, Petr Slovak

JMIR Form Res 2026 (Oct 27); 10:e103590

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Resilient Together Dyadic Intervention for Persons With Dementia and Their Partners: Protocol for a Feasibility Randomized Controlled Trial

Sarah M Bannon, Sydney M McCage, Renata Elizalde Carrillo, Stephan A Brandt, Grace O Allison, Aida Aminpour, Kristin Walker, Talea Cornelius, Robert A Parker, Kristen Dams-O'Connor, Bradford Dickerson, Christine Ritchie, Ana-Maria Vranceanu

JMIR Res Protoc 2026 (Oct 27); 15:e106005

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Woman with headset views chatbot conversation on phone, with icons for alert and doctor

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Human-in-the-Loop Suicide Risk Detection and Clinical Escalation in a Generative AI Mental Health Chatbot: Prospective Implementation Study

Suzette Glasner, Darcy Michero, Matthew Stewart

JMIR Form Res 2026 (Oct 23); 10:e106118

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Woman on video call for remote work productivity tips in home office

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Feasibility and Acceptability of Videoconference-Based Family Psychoeducation for Young Adult Caregivers of Family Members With Major Depressive Disorder: Protocol for a Pilot Randomized Controlled Trial

Hideki Nakamura, Sho Okawa, Hiroki Tanoue, Yoshihiro Goto, Akari Matsuzawa, Keiko Ito

JMIR Res Protoc 2026 (Oct 23); 15:e105182

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Online Behavioral Digital Phenotyping for Depression: Scoping Review of Behavioral Features and Exploratory Assessment of Research Domain Criteria Construct Relevance

Qiuyan Ren, Jing Chi, Yuman Li, Ping Zhao, Meiqin Luo, Jiale Sun, Yan He, Jianhong Liu, Lin Luo, Yanni Wu

J Med Internet Res 2026 (Oct 21); 28:e101329

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Assisting Screening of Adolescent Depression With Large Language Models as Symptom Detectors: Algorithm Development and Validation

Mariia Ignashina, Paulina Bondaronek, Parand Shams, Joanne Osuchukwu, Daniel Santel, John Pestian, Julia Ive

JMIR Form Res 2026 (Oct 21); 10:e71614

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Navigating Suicide-Related Online Content in Individuals With Lived Experience of Suicidality: Cross-Sectional Survey

Jacob Greaves, Dafni Katsampa, Anna Lavis, Lydia Grace, Ciara Harris, Ian Marsh, Lisa Marzano

J Med Internet Res 2026 (Oct 20); 28:e92693

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