Long-Term Effects of Internet-Based Cognitive Behavioral Therapy on Depression Prevention Among University Students: Randomized Controlled Factorial Trial

Yukako Nakagami   ^{1, 2 *} , MD, PhD ;   Teruhisa Uwatoko   ^{2, 3 *} , MD, PhD ;   Tomonari Shimamoto   ¹ , PhD ;   Masatsugu Sakata   ^{4, 5} , PhD ;   Rie Toyomoto   ⁴ , MSc ;   Kazufumi Yoshida   ⁴ , MD, DrPH ;   Yan Luo   ⁴ , MD, PhD ;   Nao Shiraishi   ⁶ , MD, PhD, MPH ;   Aran Tajika   ⁴ , MD, PhD ;   Ethan Sahker   ^{4, 7} , PhD ;   Masaru Horikoshi   ⁸ , PhD ;   Hisashi Noma   ⁹ , PhD ;   Taku Iwami   ¹ , MD, PhD ;   Toshi A Furukawa   ^{4, 10} , MD, PhD

¹ Kyoto University Health Service, Kyoto University, Kyoto, Japan

² Department of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan

³ University Health Center, Kyoto University of Education, Kyoto, Japan

⁴ Department of Health Promotion and Human Behavior, Graduate School of Medicine / School of Public Health, Kyoto University, Kyoto, Japan

⁵ Department of Neurodevelopmental Disorders, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan

⁶ Department of Psychiatry and Cognitive-Behavioral Medicine, Graduate School of Medical Science, Nagoya City University, Nagoya, Japan

⁷ Population Health and Policy Research Unit, Medical Education Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan

⁸ National Centre for Cognitive Behavior Therapy and Research, National Centre of Neurology and Psychiatry, Tokyo, Japan

⁹ Department of Interdisciplinary Statistical Mathematics, The Institute of Statistical Mathematics, Tokyo, Japan

¹⁰ Office of Institutional Advancement and Communications, Kyoto University, Kyoto, Japan

*these authors contributed equally