Incorporating Objective Behavioral and Biological Measures in a Large-Scale Decentralized Mobile Health Trial for Depression: Randomized Controlled Trial

Wendy S-Y Lau   ^{1 *} , PhD ;   Caroline M Swords   ^{1, 2 *} , BA ;   Margaret W Thairu   ³ , PhD ;   Nelson Hidalgo   ⁴ , MS ;   Raquel Tatar   ⁵ , PhD ;   Hadley Rahrig   ¹ , PhD ;   Christine D Wilson-Mendenhall   ¹ , PhD ;   Daniel W Grupe   ¹ , PhD ;   Robin I Goldman   ¹ , PhD ;   Nathaniel J Vack   ¹ , BA ;   Craig Ferguson   ⁴ , MS ;   Gabriela Valdivia   ^{1, 2} , MS ;   Kris Sankaran   ⁶ , PhD ;   Corrina Frye   ¹ , BS ;   Cortland J Dahl   ^{1, 5} , PhD ;   Robert Lewis   ⁴ , MSc, MChem ;   Estelle T Higgins   ^{1, 7} , MS ;   Mason Garza   ^{3, 8} , MS ;   Zishan Jiwani   ^{1, 2} , MA ;   Matthew J Hirshberg   ¹ , PhD ;   Amit Bernstein   ^{1, 9} , PhD ;   Ellen Converse   ^{1, 10} , MS ;   Sona Dimidjian   ¹¹ , PhD ;   Earlise C Ward   ^{1, 12} , PhD ;   Gregory E Miller   ¹³ , PhD ;   Thomas W McDade   ¹⁴ , PhD ;   Rosalind W Picard   ⁴ , ScD ;   Jo Handelsman   ^{3, 15} , PhD ;   Melissa A Rosenkranz   ^{1, 16} , PhD ;   Heather C Abercrombie   ¹ , PhD ;   Richard J Davidson   ^{1, 7} , PhD ;   Simon B Goldberg   ^{1, 2} , PhD

¹ Center for Healthy Minds, University of Wisconsin–Madison, Madison, WI, United States

² Department of Counseling Psychology, University of Wisconsin–Madison, Madison, WI, United States

³ Wisconsin Institute of Discovery, University of Wisconsin–Madison, Madison, WI, United States

⁴ MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA, United States

⁵ Humin, Madison, WI, United States

⁶ Department of Statistics, University of Wisconsin–Madison, Madison, WI, United States

⁷ Department of Psychology, University of Wisconsin–Madison, Madison, WI, United States

⁸ Department of Biomedical Engineering, University of Wisconsin–Madison, Madison, WI, United States

⁹ School of Psychological Science, University of Haifa, Haifa, Israel

¹⁰ PAU-Stanford PsyD Consortium, Palo Alto University, Palo Alto, CA, United States

¹¹ Department of Psychology and Neuroscience, Crown Institute, University of Colorado Boulder, Boulder, CO, United States

¹² Department of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin–Madison, Madison, WI, United States

¹³ Department of Psychology, Institute for Policy Research, Northwestern University, Evanston, IL, United States

¹⁴ Department of Anthropology, Northwestern University, Evanston, IL, United States

¹⁵ Department of Plant Pathology, University of Wisconsin–Madison, Madison, WI, United States

¹⁶ Department of Psychiatry, School of Medicine and Public Health, University of Wisconsin–Madison, Madison, WI, United States

*these authors contributed equally