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This paper is in the following e-collection/theme issue:

AI-Powered Therapy Bots and Virtual Companions in Digital Mental Health (79) Depression and Mood Disorders; Suicide Prevention (2393) Anxiety and Stress Disorders (1584) Chatbots and Conversational Agents (1134)

Published on in Vol 13 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/82642, first published .
Woman on a video call with a smiling blonde woman on a smartphone.

Effectiveness of a Fully Automated Mobile Therapeutic Versus a General Chatbot in Reducing Depression and Anxiety and Improving Well-Being: Feasibility Randomized Controlled Trial

Effectiveness of a Fully Automated Mobile Therapeutic Versus a General Chatbot in Reducing Depression and Anxiety and Improving Well-Being: Feasibility Randomized Controlled Trial

Authors of this article:

Barbora Kuta1 Author Orcid Image ;   Lukas Novak1 Author Orcid Image ;   Radka Zidkova1 Author Orcid Image ;   Jana Furstova1 Author Orcid Image ;   Klara Malinakova1 Author Orcid Image ;   Andrea De Winter2 Author Orcid Image ;   Vít Husek1 Author Orcid Image
Article Authors Cited by (1) Tweetations (1) Metrics

Journals

  1. Nelson B, Kalinich M, Torous J. Specialized or General-Purpose—The Wrong Question for Mental Health AI Safety. JAMA 2026 View