Machine Learning–Based Predictive Modeling of Anxiety and Depressive Symptoms During 8 Months of the COVID-19 Global Pandemic: Repeated Cross-sectional Survey Study

Katrina Hueniken   ^{1, 2} , MPH ;   Nibene Habib Somé   ^{2, 3, 4, 5, 6} , PhD ;   Mohamed Abdelhack   ¹ , PhD ;   Graham Taylor   ^{7, 8} , PhD ;   Tara Elton Marshall   ^{2, 3, 4, 6, 9, 10} , PhD ;   Christine M Wickens   ^{2, 3, 4, 11, 12} , PhD ;   Hayley A Hamilton   ^{2, 3, 4} , PhD ;   Samantha Wells   ^{2, 3, 4, 6, 13, 14} , PhD ;   Daniel Felsky   ^{1, 13, 15, 16} , PhD

¹ Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada

² Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

³ Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, ON, Canada

⁴ Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada

⁵ Institute for Clinical Evaluative Sciences, Toronto, ON, Canada

⁶ Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada

⁷ School of Engineering, University of Guelph, Guelph, ON, Canada

⁸ Vector Institute for Artificial Intelligence, Toronto, ON, Canada

⁹ School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada

¹⁰ Department of Health Sciences, Lakehead University, Thunder Bay, ON, Canada

¹¹ Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada

¹² Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada

¹³ Department of Psychiatry, University of Toronto, Toronto, ON, Canada

¹⁴ School of Psychology, Deakin University, Burwood, Australia

¹⁵ Department of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

¹⁶ Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada