Circadian Reinforcement Therapy in Combination With Electronic Self-Monitoring to Facilitate a Safe Postdischarge Period for Patients With Major Depression: Randomized Controlled Trial

Anne Sofie Aggestrup   ¹ , MSc ;   Signe Dunker Svendsen   ² , MSc ;   Anne Præstegaard   ¹ , BS ;   Philip Løventoft   ¹ , MSc ;   Lasse Nørregaard   ¹ , MSc ;   Ulla Knorr   ¹ , MD, PhD ;   Henrik Dam   ¹ , MD ;   Erik Frøkjær   ³ , MSc ;   Konstantin Danilenko   ^{4 †} , MD, PhD ;   Ida Hageman   ⁵ , MD ;   Maria Faurholt-Jepsen   ¹ , MD, DMSc ;   Lars Vedel Kessing   ¹ , MD, DMSc ;   Klaus Martiny   ¹ , MD, PhD, DMSc

¹ Mental Health Centre Copenhagen, Copenhagen University Hospital, Frederiksberg, Denmark

² Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark

³ Department of Computer Science, University of Copenhagen, Copenhagen, Denmark

⁴ Institute of Neurosciences and Medicine, Novosibirsk, Russian Federation

⁵ Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark

†deceased