This paper is in the following e-collection/theme issue:

Depression and Mood Disorders; Suicide Prevention (1272) Anxiety and Stress Disorders (1002) Chatbots and Conversational Agents (458) Artificial Intelligence (1188)

Published on in Vol 5, No 4 (2018): Oct-Dec

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/9782, first published .
Using Psychological Artificial Intelligence (Tess) to Relieve Symptoms of Depression and Anxiety: Randomized Controlled Trial

Using Psychological Artificial Intelligence (Tess) to Relieve Symptoms of Depression and Anxiety: Randomized Controlled Trial

Using Psychological Artificial Intelligence (Tess) to Relieve Symptoms of Depression and Anxiety: Randomized Controlled Trial

Authors of this article:

Russell Fulmer1 Author Orcid Image ;   Angela Joerin2 Author Orcid Image ;   Breanna Gentile2 Author Orcid Image ;   Lysanne Lakerink3 Author Orcid Image ;   Michiel Rauws2 Author Orcid Image
Article Authors Cited by (261) Tweetations (11) Metrics

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  122. Medeiros L, Bosse T, Gerritsen C. Can a Chatbot Comfort Humans? Studying the Impact of a Supportive Chatbot on Users’ Self-Perceived Stress. IEEE Transactions on Human-Machine Systems 2022;52(3):343 View
  123. Pham K, Nabizadeh A, Selek S. Artificial Intelligence and Chatbots in Psychiatry. Psychiatric Quarterly 2022;93(1):249 View
  124. Gifu D, Pop E. Smart Solutions to Keep Your Mental Balance. Procedia Computer Science 2022;214:503 View
  125. Pauw L, Sauter D, van Kleef G, Lucas G, Gratch J, Fischer A. The avatar will see you now: Support from a virtual human provides socio-emotional benefits. Computers in Human Behavior 2022;136:107368 View
  126. Krach S, Corcoran S. Will Computers Replace School Psychologists? An Analysis of Tech-Based Tools for Assessment, Consultation, and Counseling. Contemporary School Psychology 2023 View
  127. Motger Q, Franch X, Marco J. Software-Based Dialogue Systems: Survey, Taxonomy, and Challenges. ACM Computing Surveys 2023;55(5):1 View
  128. Boucher E, Harake N, Ward H, Stoeckl S, Vargas J, Minkel J, Parks A, Zilca R. Artificially intelligent chatbots in digital mental health interventions: a review. Expert Review of Medical Devices 2021;18(sup1):37 View
  129. Rocheteau E. On the role of artificial intelligence in psychiatry. The British Journal of Psychiatry 2023;222(2):54 View
  130. Kaywan P, Ahmed K, Ibaida A, Miao Y, Gu B, Saha S. Early detection of depression using a conversational AI bot: A non-clinical trial. PLOS ONE 2023;18(2):e0279743 View
  131. Gual-Montolio P, Jaén I, Martínez-Borba V, Castilla D, Suso-Ribera C. Using Artificial Intelligence to Enhance Ongoing Psychological Interventions for Emotional Problems in Real- or Close to Real-Time: A Systematic Review. International Journal of Environmental Research and Public Health 2022;19(13):7737 View
  132. Li Y, Liang S, Zhu B, Liu X, Li J, Chen D, Qin J, Bressington D. Feasibility and effectiveness of artificial intelligence-driven conversational agents in healthcare interventions: A systematic review of randomized controlled trials. International Journal of Nursing Studies 2023;143:104494 View
  133. Jabir A, Martinengo L, Lin X, Torous J, Subramaniam M, Tudor Car L. Evaluating Conversational Agents for Mental Health: Scoping Review of Outcomes and Outcome Measurement Instruments. Journal of Medical Internet Research 2023;25:e44548 View
  134. Priya P, Firdaus M, Ekbal A. A multi-task learning framework for politeness and emotion detection in dialogues for mental health counselling and legal aid. Expert Systems with Applications 2023;224:120025 View
  135. Sauerbrei A, Kerasidou A, Lucivero F, Hallowell N. The impact of artificial intelligence on the person-centred, doctor-patient relationship: some problems and solutions. BMC Medical Informatics and Decision Making 2023;23(1) View
  136. Haque M, Rubya S. An Overview of Chatbot-Based Mobile Mental Health Apps: Insights From App Description and User Reviews. JMIR mHealth and uHealth 2023;11:e44838 View
  137. Hsu M. The Construction of Critical Factors for Successfully Introducing Chatbots into Mental Health Services in the Army: Using a Hybrid MCDM Approach. Sustainability 2023;15(10):7905 View
  138. Ehrlich C, Hennelly S, Wilde N, Lennon O, Beck A, Messenger H, Sergiou K, Davies E. Evaluation of an Artificial Intelligence Enhanced Application for Student Wellbeing: Pilot Randomised Trial of the Mind Tutor. International Journal of Applied Positive Psychology 2024;9(1):435 View
  139. Smith E, Grigorian H. A System for Rapidly Yet Rigorously Evaluating the Quality of Randomized Controlled Trials. Journal of Clinical Psychopharmacology 2023;43(4):306 View
  140. Rajkishan S, Meitei A, Singh A. Role of AI/ML in the study of mental health problems of the students: a bibliometric study. International Journal of System Assurance Engineering and Management 2023 View
  141. Wutz M, Hermes M, Winter V, Köberlein-Neu J. Factors Influencing the Acceptability, Acceptance, and Adoption of Conversational Agents in Health Care: Integrative Review. Journal of Medical Internet Research 2023;25:e46548 View
  142. Ramya J, Alur S. Unleashing the potential of chatbots in business: A bibliometric analysis. Business Information Review 2023;40(3):123 View
  143. Iqbal J, Cortés Jaimes D, Makineni P, Subramani S, Hemaida S, Thugu T, Butt A, Sikto J, Kaur P, Lak M, Augustine M, Shahzad R, Arain M. Reimagining Healthcare: Unleashing the Power of Artificial Intelligence in Medicine. Cureus 2023 View
  144. Stanton B, Chalder T, Carvalho C. Cognitive behavioural therapy for neurologists. Practical Neurology 2024;24(1):22 View
  145. Chin H, Song H, Baek G, Shin M, Jung C, Cha M, Choi J, Cha C. The Potential of Chatbots for Emotional Support and Promoting Mental Well-Being in Different Cultures: Mixed Methods Study. Journal of Medical Internet Research 2023;25:e51712 View
  146. Otero-González I, Pacheco-Lorenzo M, Fernández-Iglesias M, Anido-Rifón L. Conversational agents for depression screening: A systematic review. International Journal of Medical Informatics 2024;181:105272 View
  147. Lee M, Contreras Alejandro J, IJsselsteijn W. Cultivating Gratitude with a Chatbot. International Journal of Human–Computer Interaction 2023:1 View
  148. Lopes E, Jain G, Carlbring P, Pareek S. Talking Mental Health: a Battle of Wits Between Humans and AI. Journal of Technology in Behavioral Science 2023 View
  149. Nashwan A, Gharib S, Alhadidi M, El-Ashry A, Alamgir A, Al-Hassan M, Khedr M, Dawood S, Abufarsakh B. Harnessing Artificial Intelligence: Strategies for Mental Health Nurses in Optimizing Psychiatric Patient Care. Issues in Mental Health Nursing 2023;44(10):1020 View
  150. Avula V, Amalakanti S. Artificial intelligence in psychiatry, present trends, and challenges: An updated review. Archives of Mental Health 2024;25(1):85 View
  151. Wrightson-Hester A, Anderson G, Dunstan J, McEvoy P, Sutton C, Myers B, Egan S, Tai S, Johnston-Hollitt M, Chen W, Gedeon T, Mansell W. An Artificial Therapist (Manage Your Life Online) to Support the Mental Health of Youth: Co-Design and Case Series. JMIR Human Factors 2023;10:e46849 View
  152. Chou Y, Lin C, Lee S, Chang Chien Y, Cheng L. Potential Mobile Health Applications for Improving the Mental Health of the Elderly: A Systematic Review. Clinical Interventions in Aging 2023;Volume 18:1523 View
  153. Arntz A, Weber F, Handgraaf M, Lällä K, Korniloff K, Murtonen K, Chichaeva J, Kidritsch A, Heller M, Sakellari E, Athanasopoulou C, Lagiou A, Tzonichaki I, Salinas-Bueno I, Martínez-Bueso P, Velasco-Roldán O, Schulz R, Grüneberg C. Technologies in Home-Based Digital Rehabilitation: Scoping Review. JMIR Rehabilitation and Assistive Technologies 2023;10:e43615 View
  154. Ahuja K, DeSena G, Laageide L, El‐Feghaly J, Lio P. From eczema to anxiety: How artificial intelligence  shapes parental perspectives. Pediatric Dermatology 2023;40(5):964 View
  155. Martin R, Richmond S. Conversational agents for Children's mental health and mental disorders: A scoping review. Computers in Human Behavior: Artificial Humans 2023;1(2):100028 View
  156. Podina I, Bucur A, Fodor L, Boian R. Screening for common mental health disorders: a psychometric evaluation of a chatbot system. Behaviour & Information Technology 2023:1 View
  157. Mancone S, Diotaiuti P, Valente G, Corrado S, Bellizzi F, Vilarino G, Andrade A. The Use of Voice Assistant for Psychological Assessment Elicits Empathy and Engagement While Maintaining Good Psychometric Properties. Behavioral Sciences 2023;13(7):550 View
  158. Dempere J, Modugu K, Hesham A, Ramasamy L. The impact of ChatGPT on higher education. Frontiers in Education 2023;8 View
  159. Adus S, Macklin J, Pinto A. Exploring patient perspectives on how they can and should be engaged in the development of artificial intelligence (AI) applications in health care. BMC Health Services Research 2023;23(1) View
  160. Daza A, Arroyo-Paz , Bobadilla J, Apaza O, Pinto J. Stacking ensemble learning model for predict anxiety level in university students using balancing methods. Informatics in Medicine Unlocked 2023;42:101340 View
  161. Rakers M, van de Vijver S, Bossio P, Moens N, Rauws M, Orera M, Shen H, Hallensleben C, Brakema E, Guldemond N, Chavannes N, Villalobos-Quesada M. SERIES: eHealth in primary care. Part 6: Global perspectives: Learning from eHealth for low-resource primary care settings and across high-, middle- and low-income countries. European Journal of General Practice 2023;29(1) View
  162. Viduani A, Cosenza V, Fisher H, Buchweitz C, Piccin J, Pereira R, Kohrt B, Mondelli V, van Heerden A, Araújo R, Kieling C. Assessing Mood With the Identifying Depression Early in Adolescence Chatbot (IDEABot): Development and Implementation Study. JMIR Human Factors 2023;10:e44388 View
  163. Terra M, Baklola M, Ali S, El-Bastawisy K. Opportunities, applications, challenges and ethical implications of artificial intelligence in psychiatry: a narrative review. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 2023;59(1) View
  164. Jabir A, Lin X, Martinengo L, Sharp G, Theng Y, Tudor Car L. Attrition in Conversational Agent–Delivered Mental Health Interventions: Systematic Review and Meta-Analysis. Journal of Medical Internet Research 2024;26:e48168 View
  165. Sharma R, Mirzakhalov J, Bharti P, Goyal R, Schmidt T, Chellappan S. A Friend in Need Is a Friend Indeed: Investigating the Quality of Training Data from Peers for Auto-generating Empathetic Textual Responses to Non-Sensitive Posts in a Cohort of College Students. ACM Journal on Computing and Sustainable Societies 2023;1(2):1 View
  166. Ding H, Simmich J, Vaezipour A, Andrews N, Russell T. Evaluation framework for conversational agents with artificial intelligence in health interventions: a systematic scoping review. Journal of the American Medical Informatics Association 2024;31(3):746 View
  167. Li H, Zhang R, Lee Y, Kraut R, Mohr D. Systematic review and meta-analysis of AI-based conversational agents for promoting mental health and well-being. npj Digital Medicine 2023;6(1) View
  168. Čartolovni A, Malešević A, Poslon L. Critical analysis of the AI impact on the patient–physician relationship: A multi-stakeholder qualitative study. DIGITAL HEALTH 2023;9 View
  169. Allen C, Neil G, Halbert C, Sterba K, Nietert P, Welch B, Lenert L. Barriers and facilitators to the implementation of family cancer history collection tools in oncology clinical practices. Journal of the American Medical Informatics Association 2024;31(3):631 View
  170. Munnik J, Noorbhai H. Artificial intelligence in psychology: a commentary on AI’s emerging role and the ensuing conversation. South African Journal of Psychology 2024 View
  171. Cheng S, Kopelovich S, Si D, Divina M, Gao N, Wang M, Kim J, Li Z, Blank J, Brian R, Turkington D. Co-Production of a Cognitive Behavioral Therapy Digital Platform for Families of Individuals Impacted by Psychosis. Journal of Technology in Behavioral Science 2024;9(1):140 View
  172. Qi Y. Pilot Quasi-Experimental Research on the Effectiveness of the Woebot AI Chatbot for Reducing Mild Depression Symptoms among Athletes. International Journal of Human–Computer Interaction 2024:1 View
  173. Maples B, Cerit M, Vishwanath A, Pea R. Loneliness and suicide mitigation for students using GPT3-enabled chatbots. npj Mental Health Research 2024;3(1) View
  174. Singh V, Sarkar S, Gaur V, Grover S, Singh O. Clinical Practice Guidelines on using artificial intelligence and gadgets for mental health and well-being. Indian Journal of Psychiatry 2024;66(Suppl 2):S414 View
  175. Gopalakrishnan A, Gururajan R, Zhou X, Venkataraman R, Chan K, Higgins N. A survey of autonomous monitoring systems in mental health. WIREs Data Mining and Knowledge Discovery 2024;14(3) View
  176. Chiauzzi E, Williams A, Mariano T, Pajarito S, Robinson A, Kirvin-Quamme A, Forman-Hoffman V. Demographic and clinical characteristics associated with anxiety and depressive symptom outcomes in users of a digital mental health intervention incorporating a relational agent. BMC Psychiatry 2024;24(1) View
  177. Pedersen H, Skliarova T, Pedersen S, Gråwe R, Havnen A, Lara-Cabrera M. Psychoeducation for adult ADHD: a scoping review about characteristics, patient involvement, and content. BMC Psychiatry 2024;24(1) View
  178. Gültekin M, Şahin M. The use of artificial intelligence in mental health services in Turkey: What do mental health professionals think?. Cyberpsychology: Journal of Psychosocial Research on Cyberspace 2024;18(1) View
  179. Lee J, You J, Lee D. User Preferences on AI Psychotherapy Based on Moderating Effects of Individual Personality Traits: Employing a Clustering Analysis. International Journal of Human–Computer Interaction 2024:1 View
  180. Li D, Kao Y, Tsai S, Bai Y, Yeh T, Chu C, Hsu C, Cheng S, Hsu T, Liang C, Su K. Comparing the performance of ChatGPT GPT‐4, Bard, and Llama‐2 in the Taiwan Psychiatric Licensing Examination and in differential diagnosis with multi‐center psychiatrists. Psychiatry and Clinical Neurosciences 2024;78(6):347 View
  181. Galdo B, Pazos C, Pardo J, Solar A, Llamas D, Fernández-Blanco E, Pazos A. Inteligencia artificial en pediatría: actualidad y retos. Anales de Pediatría 2024;100(3):195 View
  182. Galdo B, Pazos C, Pardo J, Solar A, Llamas D, Fernández-Blanco E, Pazos A. Artificial intelligence in paediatrics: Current events and challenges. Anales de Pediatría (English Edition) 2024;100(3):195 View
  183. Herbener A, Klincewicz M, Damholdt M. A narrative review of the active ingredients in psychotherapy delivered by conversational agents. Computers in Human Behavior Reports 2024;14:100401 View
  184. El Sherbini A, Rosenson R, Al Rifai M, Virk H, Wang Z, Virani S, Glicksberg B, Lavie C, Krittanawong C. Artificial intelligence in preventive cardiology. Progress in Cardiovascular Diseases 2024 View
  185. Shidara K, Tanaka H, Adachi H, Kanayama D, Kudo T, Nakamura S. Adapting the Number of Questions Based on Detected Psychological Distress for Cognitive Behavioral Therapy With an Embodied Conversational Agent: Comparative Study. JMIR Formative Research 2024;8:e50056 View
  186. Crawford J, Allen K, Pani B, Cowling M. When artificial intelligence substitutes humans in higher education: the cost of loneliness, student success, and retention. Studies in Higher Education 2024;49(5):883 View
  187. MacNeill A, MacNeill L, Yi S, Goudreau A, Luke A, Doucet S. Depiction of conversational agents as health professionals: a scoping review. JBI Evidence Synthesis 2024;22(5):831 View
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Books/Policy Documents

  1. Singla S. Internet of Things Use Cases for the Healthcare Industry. View
  2. Musyimi C, Lai Y, Mutiso V, Ndetei D. Innovations in Global Mental Health. View
  3. Croes E, Antheunis M. Chatbot Research and Design. View
  4. Fisher H. Logic, Syntax, and a Structural View. View
  5. Glauner P. Digitalization in Healthcare. View
  6. Jox R. Clinical Neurotechnology meets Artificial Intelligence. View
  7. Denecke K, Abd-Alrazaq A, Househ M. Multiple Perspectives on Artificial Intelligence in Healthcare. View
  8. Gundavarapu M, Saaketh Koundinya G, Bollina Devi Sai T, Kidambi Sree G. Applied Computational Technologies. View
  9. Glauner P. Innovationen im Gesundheitswesen. View
  10. Rauws M. Artificial Intelligence in Medicine. View
  11. Bickmore T, O'Leary T. Digital Therapeutics for Mental Health and Addiction. View
  12. Olaniyan O, Adetunji C, Dare A, Adeyomoye O, Adeniyi M, Enoch A. Artificial Intelligence for Neurological Disorders. View
  13. Rauws M. Artificial Intelligence in Medicine. View
  14. Chehbi Gamoura S, Koruca H, Arslan Kazan C. Smart Applications with Advanced Machine Learning and Human-Centred Problem Design. View
  15. Podina I, Caculidis-Tudor D. Brain, Decision Making and Mental Health. View
  16. Das A, Sen V, Rose A. Augmenting Neurological Disorder Prediction and Rehabilitation Using Artificial Intelligence. View
  17. Musyimi C, Lai Y, Mutiso V, Ndetei D. Innovations in Global Mental Health. View
  18. Jiménez-Molina Á, Franco P, Mac-Ginty S, Martínez V. Prevention and Early Treatment of Depression Through the Life Course. View
  19. Dhimolea T, Kaplan-Rakowski R, Lin L. Bridging Human Intelligence and Artificial Intelligence. View
  20. Viduani A, Cosenza V, Araújo R, Kieling C. Digital Mental Health. View
  21. Alloghani M, Thron C, Subair S. Artificial Intelligence for Data Science in Theory and Practice. View
  22. Das A, Day T, Kulkarni V, Buchanan A, Cottrell K, John N, Chatterjee K. Augmenting Neurological Disorder Prediction and Rehabilitation Using Artificial Intelligence. View
  23. May S, Szczypien N, Vahldiek K, Klawonn F. Assistive Technologien im Sozial- und Gesundheitssektor. View
  24. Lucero Fredes A, Cano S, Cubillos C, Díaz M. HCI International 2022 – Late Breaking Papers: HCI for Health, Well-being, Universal Access and Healthy Aging. View
  25. Mattioli M. Governing Privacy in Knowledge Commons. View
  26. Henkel T, Linn A, van der Goot M. Chatbot Research and Design. View
  27. El Rhatassi F, El Ghali B, Daoudi N. Digital Technologies and Applications. View
  28. Pollard J, Quigley S, O’Brien M, Peterson S, Casey S. Handbook of Applied Behavior Analysis. View
  29. Del Fiol G. Clinical Decision Support and Beyond. View
  30. Nazarova D. Proceedings of the Future Technologies Conference (FTC) 2023, Volume 1. View
  31. Afrin Z, Farid D, Mamun K. Intelligent Systems and Data Science. View
  32. Striegl J, Loitsch C, Weber G. Human-Computer Interaction. View
  33. Amorese T, McConvey G, Cuciniello M, Cordasco G, Bond R, Mulvenna M, Ennis E, Callejas Z, Esposito A. Proceedings of Eighth International Congress on Information and Communication Technology. View
  34. Denecke K. Sentiment Analysis in the Medical Domain. View
  35. Singh S, Joshi R, Jain P, Abilash K. Emotional AI and Human-AI Interactions in Social Networking. View
  36. Machado A, Ferreira B, Pereira C, Carrola C, de Melo B, Campos C. Handbook of Research on Advances in Digital Technologies to Promote Rehabilitation and Community Participation. View
  37. . Artificial and Cognitive Computing for Sustainable Healthcare Systems in Smart Cities. View