This paper is in the following e-collection/theme issue:

Depression and Mood Disorders; Suicide Prevention (1071) Text-messaging (SMS, WeChat etc)-Based Interventions (548) Anxiety and Stress Disorders (842) Chatbots and Conversational Agents (203)

Published on in Vol 4 , No 2 (2017) :Apr-Jun

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Delivering Cognitive Behavior Therapy to Young Adults With Symptoms of Depression and Anxiety Using a Fully Automated Conversational Agent (Woebot): A Randomized Controlled Trial

Authors of this article:

Kathleen Kara Fitzpatrick 1 Author Orcid Image ;   Alison Darcy 2 Author Orcid Image ;   Molly Vierhile 1 Author Orcid Image
Article Authors Cited by (709) Tweetations (342) Metrics

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  379. Khalili-Mahani N, Holowka E, Woods S, Khaled R, Roy M, Lashley M, Glatard T, Timm-Bottos J, Dahan A, Niesters M, Hovey R, Simon B, Kirmayer L. Play the Pain: A Digital Strategy for Play-Oriented Research and Action. Frontiers in Psychiatry 2021;12 View
  380. Ludin N, Holt-Quick C, Hopkins S, Stasiak K, Hetrick S, Warren J, Cargo T. A Chatbot to Support Young People During the COVID-19 Pandemic in New Zealand: Evaluation of the Real-World Rollout of an Open Trial. Journal of Medical Internet Research 2022;24(11):e38743 View
  381. Krach S, Corcoran S. Will Computers Replace School Psychologists? An Analysis of Tech-Based Tools for Assessment, Consultation, and Counseling. Contemporary School Psychology 2023 View
  382. Figueroa C, Luo T, Jacobo A, Munoz A, Manuel M, Chan D, Canny J, Aguilera A. Conversational Physical Activity Coaches for Spanish and English Speaking Women: A User Design Study. Frontiers in Digital Health 2021;3 View
  383. Chen X, Luo Y. Digital Therapeutics in Migraine Management: A Novel Treatment Option in the COVID-19 Era. Journal of Pain Research 2023;Volume 16:111 View
  384. Diano F, Sica L, Ponticorvo M. A Systematic Review of Mobile Apps as an Adjunct to Psychological Interventions for Emotion Dysregulation. International Journal of Environmental Research and Public Health 2023;20(2):1431 View
  385. Ollier J, Neff S, Dworschak C, Sejdiji A, Santhanam P, Keller R, Xiao G, Asisof A, Rüegger D, Bérubé C, Hilfiker Tomas L, Neff J, Yao J, Alattas A, Varela-Mato V, Pitkethly A, Vara M, Herrero R, Baños R, Parada C, Agatheswaran R, Villalobos V, Keller O, Chan W, Mishra V, Jacobson N, Stanger C, He X, von Wyl V, Weidt S, Haug S, Schaub M, Kleim B, Barth J, Witt C, Scholz U, Fleisch E, Wangenheim F, Car L, Müller-Riemenschneider F, Hauser-Ulrich S, Asomoza A, Salamanca-Sanabria A, Mair J, Kowatsch T. Elena+ Care for COVID-19, a Pandemic Lifestyle Care Intervention: Intervention Design and Study Protocol. Frontiers in Public Health 2021;9 View
  386. Wu X, Du J, Jiang H, Zhao M. Application of Digital Medicine in Addiction. Journal of Shanghai Jiaotong University (Science) 2022;27(2):144 View
  387. van Bussel M, Odekerken–Schröder G, Ou C, Swart R, Jacobs M. Analyzing the determinants to accept a virtual assistant and use cases among cancer patients: a mixed methods study. BMC Health Services Research 2022;22(1) View
  388. Ćosić K, Popović S, Šarlija M, Kesedžić I, Gambiraža M, Dropuljić B, Mijić I, Henigsberg N, Jovanovic T. AI-Based Prediction and Prevention of Psychological and Behavioral Changes in Ex-COVID-19 Patients. Frontiers in Psychology 2021;12 View
  389. Paton L, Tiffin P. Technology Matters: Machine learning approaches to personalised child and adolescent mental health care. Child and Adolescent Mental Health 2022;27(3):307 View
  390. Eagle T, Mehrotra A, Sharma A, Zuniga A, Whittaker S. "Money Doesn't Buy You Happiness": Negative Consequences of Using the Freemium Model for Mental Health Apps. Proceedings of the ACM on Human-Computer Interaction 2022;6(CSCW2):1 View
  391. Lima M, Wairagkar M, Gupta M, Rodriguez y Baena F, Barnaghi P, Sharp D, Vaidyanathan R. Conversational Affective Social Robots for Ageing and Dementia Support. IEEE Transactions on Cognitive and Developmental Systems 2022;14(4):1378 View
  392. Parmar P, Ryu J, Pandya S, Sedoc J, Agarwal S. Health-focused conversational agents in person-centered care: a review of apps. npj Digital Medicine 2022;5(1) View
  393. Merkouris S, Loram G, Abdelrazek M, Rodda S, Ibrahim A, Bonti A, Dowling N. Improving the user experience of a gambling support and education website using a chatbot. Universal Access in the Information Society 2022 View
  394. Thieme A, Hanratty M, Lyons M, Palacios J, Marques R, Morrison C, Doherty G. Designing Human-centered AI for Mental Health: Developing Clinically Relevant Applications for Online CBT Treatment. ACM Transactions on Computer-Human Interaction 2023;30(2):1 View
  395. Xu L, Sanders L, Li K, Chow J. Chatbot for Health Care and Oncology Applications Using Artificial Intelligence and Machine Learning: Systematic Review. JMIR Cancer 2021;7(4):e27850 View
  396. Lopatovska I, Turpin O, Yoon J, Brown D, Vroom L, Nielsen C, Hayes K, Roslund K, Dickson M, Anger D. Measuring the Impact of Conversational Technology Interventions on Adolescent Wellbeing: Quantitative and Qualitative Approaches. Proceedings of the Association for Information Science and Technology 2022;59(1):192 View
  397. Koulouri T, Macredie R, Olakitan D. Chatbots to Support Young Adults’ Mental Health: An Exploratory Study of Acceptability. ACM Transactions on Interactive Intelligent Systems 2022;12(2):1 View
  398. Eagle T, Blau C, Bales S, Desai N, Li V, Whittaker S. “I don’t know what you mean by `I am anxious'”: A New Method for Evaluating Conversational Agent Responses to Standardized Mental Health Inputs for Anxiety and Depression. ACM Transactions on Interactive Intelligent Systems 2022;12(2):1 View
  399. Pacheco C, Scheeringa M. Clinical wisdom in the age of computer apps: a systematic review of four functions that may complement clinical treatment. The Cognitive Behaviour Therapist 2022;15 View
  400. Pham M, Do H, Su Z, Bishop A, Sheng W. Negative Emotion Management Using a Smart Shirt and a Robot Assistant. IEEE Robotics and Automation Letters 2021;6(2):4040 View
  401. Lomis K, Jeffries P, Palatta A, Sage M, Sheikh J, Sheperis C, Whelan A. Artificial Intelligence for Health Professions Educators. NAM Perspectives 2021 View
  402. Lipschitz J, Van Boxtel R, Torous J, Firth J, Lebovitz J, Burdick K, Hogan T. Digital Mental Health Interventions for Depression: Scoping Review of User Engagement. Journal of Medical Internet Research 2022;24(10):e39204 View
  403. GÜLTEKİN M. Could Robots Empatize? A Review on The Employment of Social Robots in Mental Healthcare. Türk Psikolojik Danışma ve Rehberlik Dergisi 2022;12(67) View
  404. Balaskas A, Schueller S, Cox A, Rashleigh C, Doherty G, Tizzoni M. Examining young adults daily perspectives on usage of anxiety apps: A user study. PLOS Digital Health 2023;2(1):e0000185 View
  405. Hu J, Huang Y, Hu X, Xu Y. The Acoustically Emotion-Aware Conversational Agent With Speech Emotion Recognition and Empathetic Responses. IEEE Transactions on Affective Computing 2023;14(1):17 View
  406. GÜLTEKİN M. Could Robots Empatize? A Review on The Employment of Social Robots in Mental Healthcare. Türk Psikolojik Danışma ve Rehberlik Dergisi 2022;12(67):593 View
  407. Dhinagaran D, Martinengo L, Ho M, Joty S, Kowatsch T, Atun R, Tudor Car L. Designing, Developing, Evaluating, and Implementing a Smartphone-Delivered, Rule-Based Conversational Agent (DISCOVER): Development of a Conceptual Framework. JMIR mHealth and uHealth 2022;10(10):e38740 View
  408. Trappey A, Lin A, Hsu K, Trappey C, Tu K. Development of an Empathy-Centric Counseling Chatbot System Capable of Sentimental Dialogue Analysis. Processes 2022;10(5):930 View
  409. Martinengo L, Jabir A, Goh W, Lo N, Ho M, Kowatsch T, Atun R, Michie S, Tudor Car L. Conversational Agents in Health Care: Scoping Review of Their Behavior Change Techniques and Underpinning Theory. Journal of Medical Internet Research 2022;24(10):e39243 View
  410. Kaywan P, Ahmed K, Ibaida A, Miao Y, Gu B, Saha S. Early detection of depression using a conversational AI bot: A non-clinical trial. PLOS ONE 2023;18(2):e0279743 View
  411. Zhao X, Kumar A. Research on Athlete Behavior Recognition Technology in Sports Teaching Video Based on Deep Neural Network. Computational Intelligence and Neuroscience 2022;2022:1 View
  412. Abdulrahman A, Richards D. In Search of Embodied Conversational and Explainable Agents for Health Behaviour Change and Adherence. Multimodal Technologies and Interaction 2021;5(9):56 View
  413. Denecke K, Vaaheesan S, Arulnathan A. A Mental Health Chatbot for Regulating Emotions (SERMO) - Concept and Usability Test. IEEE Transactions on Emerging Topics in Computing 2021;9(3):1170 View
  414. Jeong S, Aymerich-Franch L, Arias K, Alghowinem S, Lapedriza A, Picard R, Park H, Breazeal C. Deploying a robotic positive psychology coach to improve college students’ psychological well-being. User Modeling and User-Adapted Interaction 2023;33(2):571 View
  415. Luo B, Lau R, Li C, Si Y. A critical review of state‐of‐the‐art chatbot designs and applications. WIREs Data Mining and Knowledge Discovery 2022;12(1) View
  416. Mercer C. Mental and Spiritual Health Needs of Cognitively Enhanced People: A Therapeutic and Spiritual Care Model for Responding. Religions 2022;13(8):701 View
  417. Bendig E, Erb B, Schulze-Thuesing L, Baumeister H. Die nächste Generation: Chatbots in der klinischen Psychologie und Psychotherapie zur Förderung mentaler Gesundheit – Ein Scoping-Review. Verhaltenstherapie 2019;29(4):266 View
  418. Pham K, Nabizadeh A, Selek S. Artificial Intelligence and Chatbots in Psychiatry. Psychiatric Quarterly 2022;93(1):249 View
  419. Milne-Ives M, Selby E, Inkster B, Lam C, Meinert E, Narasimhan P. Artificial intelligence and machine learning in mobile apps for mental health: A scoping review. PLOS Digital Health 2022;1(8):e0000079 View
  420. Zhu Y, Wang R, Pu C. “I am chatbot, your virtual mental health adviser.” What drives citizens’ satisfaction and continuance intention toward mental health chatbots during the COVID-19 pandemic? An empirical study in China. DIGITAL HEALTH 2022;8:205520762210900 View
  421. Ray A, Bhardwaj A, Malik Y, Singh S, Gupta R. Artificial intelligence and Psychiatry: An overview. Asian Journal of Psychiatry 2022;70:103021 View
  422. Stiede J, Trent E, Viana A, Guzick A, Storch E, Hershfield J. Cognitive Behavioral Therapy for Children and Adolescents with Anxiety Disorders. Child and Adolescent Psychiatric Clinics of North America 2023 View
  423. Qin X, Liu C, Zhu W, Chen Y, Wang Y. Preventing Postpartum Depression in the Early Postpartum Period Using an App-Based Cognitive Behavioral Therapy Program: A Pilot Randomized Controlled Study. International Journal of Environmental Research and Public Health 2022;19(24):16824 View
  424. Kornfield R, Mohr D, Ranney R, Lattie E, Meyerhoff J, Williams J, Reddy M. Involving Crowdworkers with Lived Experience in Content-Development for Push-Based Digital Mental Health Tools: Lessons Learned from Crowdsourcing Mental Health Messages. Proceedings of the ACM on Human-Computer Interaction 2022;6(CSCW1):1 View
  425. Rabinowitz A, Collier G, Vaccaro M, Wingfield R. Development of RehaBot—A Conversational Agent for Promoting Rewarding Activities in Users With Traumatic Brain Injury. Journal of Head Trauma Rehabilitation 2022;37(3):144 View
  426. Deepaisarn S, Imkome E, Wongpatikaseree K, Yuenyong S, Lakanavisid P, Soonthornchaiva R, Yomaboot P, Angkoonsawaengsuk A, Munpansa N. Validation of a Thai artificial chatmate designed for cheering up the elderly during the COVID-19 pandemic. F1000Research 2022;11:1411 View
  427. Gupta M, Malik T, Sinha C. Delivery of a Mental Health Intervention for Chronic Pain Through an Artificial Intelligence–Enabled App (Wysa): Protocol for a Prospective Pilot Study. JMIR Research Protocols 2022;11(3):e36910 View
  428. Cho E, Motalebi N, Sundar S, Abdullah S. Alexa as an Active Listener: How Backchanneling Can Elicit Self-Disclosure and Promote User Experience. Proceedings of the ACM on Human-Computer Interaction 2022;6(CSCW2):1 View
  429. Chaudhry B, Islam A. A Mobile Application-Based Relational Agent as a Health Professional for COVID-19 Patients: Design, Approach, and Implications. International Journal of Environmental Research and Public Health 2022;19(21):13794 View
  430. Zhou S, Zhao J, Zhang L. Application of Artificial Intelligence on Psychological Interventions and Diagnosis: An Overview. Frontiers in Psychiatry 2022;13 View
  431. Ahmed A, Hassan A, Aziz S, Abd-alrazaq A, Ali N, Alzubaidi M, Al-Thani D, Elhusein B, Siddig M, Ahmed M, Househ M. Chatbot features for anxiety and depression: A scoping review. Health Informatics Journal 2023;29(1):146045822211467 View
  432. Phan Q, Tseng C, Thi Hoai Le T, Nguyen T. The application of chatbot on Vietnamese misgrant workers’ right protection in the implementation of new generation free trade agreements (FTAS). AI & SOCIETY 2022 View
  433. Entenberg G, Mizrahi S, Walker H, Aghakhani S, Mostovoy K, Carre N, Marshall Z, Dosovitsky G, Benfica D, Rousseau A, Lin G, Bunge E. AI-based chatbot micro-intervention for parents: Meaningful engagement, learning, and efficacy. Frontiers in Psychiatry 2023;14 View
  434. Bendig E, Erb B, Schulze-Thuesing L, Baumeister H. The Next Generation: Chatbots in Clinical Psychology and Psychotherapy to Foster Mental Health – A Scoping Review. Verhaltenstherapie 2019:1 View
  435. Vertsberger D, Naor N, Winsberg M. Adolescents’ Well-being While Using a Mobile Artificial Intelligence–Powered Acceptance Commitment Therapy Tool: Evidence From a Longitudinal Study. JMIR AI 2022;1(1):e38171 View
  436. Vereschagin M, Wang A, Leung C, Richardson C, Hudec K, Doan Q, Virk P, Halli P, Wojcik K, Munro L, Chai B, Mori T, Sha M, Mittertreiner E, Farkouh A, Sigamany D, Vigo D. Co-developing tools to support student mental health and substance use: Minder app development from conceptualization to realization. Journal of Behavioral and Cognitive Therapy 2023;33(1):35 View
  437. González A, Geiskkovitch D, Young J. Say what you want, I’m not listening!. i-com 2023;22(1):19 View
  438. Kettle L, Lee Y. User Experiences of Well-Being Chatbots. Human Factors: The Journal of the Human Factors and Ergonomics Society 2023:001872082311624 View
  439. He Y, Yang L, Qian C, Li T, Su Z, Zhang Q, Hou X. Conversational Agent Interventions for Mental Health Problems: Systematic Review and Meta-analysis of Randomized Controlled Trials. Journal of Medical Internet Research 2023;25:e43862 View
  440. Kazi F, Sandbulte J. Examining a social-based system with personalized recommendations to promote mental health for college students. Smart Health 2023;28:100385 View
  441. Tanaka H, Saga T, Iwauchi K, Honda M, Morimoto T, Matsuda Y, Uratani M, Okazaki K, Nakamura S. The Validation of Automated Social Skills Training in Members of the General Population Over 4 Weeks: Comparative Study. JMIR Formative Research 2023;7:e44857 View
  442. Sujan M, White S, Habli I, Reynolds N. Stakeholder Perceptions of the Safety and Assurance of Artificial Intelligence in Healthcare. SSRN Electronic Journal 2022 View
  443. Nguyen H, Lopez J, Homer B, Ali A, Ahn J. Reminders, reflections, and relationships: insights from the design of a chatbot for college advising. Information and Learning Sciences 2023;124(3/4):128 View
  444. Lin Y, Yu Z. A bibliometric analysis of artificial intelligence chatbots in educational contexts. Interactive Technology and Smart Education 2023 View
  445. Bhattacharjee A, Chen P, Mandal A, Zhou L, Aggarwal J, Hsu A, O'Leary K, Mariakakis A, Williams J. Exploring User Perspectives on Brief Reflective Questioning Activities for Stress Management. SSRN Electronic Journal 2022 View
  446. Braddock W, Ocasio M, Comulada W, Mandini J, Fernàndez M. Developing an SMS Chatbot to Increase Participation in a TelePrEP Program for Sexual and Gender Minority Adolescents and Young Adults in Louisiana: Protocol Design (Preprint). JMIR Research Protocols 2022 View
  447. Jabir A, Martinengo L, Lin X, Torous J, Subramaniam M, Tudor Car L. Evaluating Conversational Agents for Mental Health: Scoping Review of Outcomes and Outcome Measurement Instruments. Journal of Medical Internet Research 2023;25:e44548 View
  448. Lee J, Lee J, Lee D. Influence of Rapport and Social Presence with an Ai Psychotherapy Chatbot on Users’ Self-Disclosure. SSRN Electronic Journal 2022 View
  449. Anmella G, Sanabra M, Primé-Tous M, Segú X, Cavero M, Morilla I, Grande I, Ruiz V, Mas A, Martín-Villalba I, Caballo A, Esteva J, Rodríguez-Rey A, Piazza F, Valdesoiro F, Rodriguez-Torrella C, Espinosa M, Virgili G, Sorroche C, Ruiz A, Solanes A, Radua J, Also M, Sant E, Murgui S, Sans-Corrales M, H Young A, Vicens V, Blanch J, Caballeria E, López-Pelayo H, López C, Olivé V, Pujol L, Quesada S, Solé B, Torrent C, Martínez-Aran A, Guarch J, Navinés R, Murru A, Fico G, de Prisco M, Oliva V, Amoretti S, Pio-Carrino C, Fernández-Canseco M, Villegas M, Vieta E, Hidalgo-Mazzei D. Vickybot, a Chatbot for Anxiety-Depressive Symptoms and Work-Related Burnout in Primary Care and Health Care Professionals: Development, Feasibility, and Potential Effectiveness Studies. Journal of Medical Internet Research 2023;25:e43293 View
  450. Priya P, Firdaus M, Ekbal A. A multi-task learning framework for politeness and emotion detection in dialogues for mental health counselling and legal aid. Expert Systems with Applications 2023;224:120025 View
  451. Li Y, Liang S, Zhu B, Liu X, Li J, Chen D, Qin J, Bressington D. Feasibility and effectiveness of artificial intelligence-driven conversational agents in healthcare interventions: A systematic review of randomized controlled trials. International Journal of Nursing Studies 2023;143:104494 View
  452. Rahman M. AI for ADHD: Opportunities and Challenges. Journal of Attention Disorders 2023:108705472311676 View
  453. Vagwala M, Asher R. Conversational Artificial Intelligence and Distortions of the Psychotherapeutic Frame: Issues of Boundaries, Responsibility, and Industry Interests. The American Journal of Bioethics 2023;23(5):28 View
  454. Kola I, Jonker C, Riemsdijk M. Using psychological characteristics of situations for social situation comprehension in support agents. Autonomous Agents and Multi-Agent Systems 2023;37(2) View
  455. Haque M, Rubya S. An Overview of Chatbot Based Mobile Mental Health Applica-tions: Insights from App Description and User Reviews (Preprint). JMIR mHealth and uHealth 2022 View
  456. Huang M, Weng C, Kuo H, Su Y. Using a chatbot to reduce emergency department visits and unscheduled hospitalizations among patients with gynecologic malignancies during chemotherapy: A retrospective cohort study. Heliyon 2023;9(5):e15798 View
  457. Iku-Silan A, Hwang G, Chen C. Decision-guided chatbots and cognitive styles in interdisciplinary learning. Computers & Education 2023;201:104812 View
  458. Batanova E, Birmpa I, Meisser G. Use of Machine Learning to classify clinical research to identify applicable compliance requirements. Informatics in Medicine Unlocked 2023;39:101255 View
  459. Park G, Lee S, Chung J. Do Anthropomorphic Chatbots Increase Counseling Satisfaction and Reuse Intention? The Moderated Mediation of Social Rapport and Social Anxiety. Cyberpsychology, Behavior, and Social Networking 2023;26(5):357 View
  460. Sulis E, Mariani S, Montagna S. A survey on agents applications in healthcare: Opportunities, challenges and trends. Computer Methods and Programs in Biomedicine 2023;236:107525 View
  461. Han H, Mendu S, Jaworski B, Owen J, Abdullah S. Preliminary Evaluation of a Conversational Agent to Support Self-management of Individuals Living with PTSD: An Interview Study with Clinical Experts (Preprint). JMIR Formative Research 2023 View
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