Pain in Children and Adolescents

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

Courtney W Hess, Brittany N Rosenbloom, Giulia Mesaroli, Cristal Lopez, Nhat Ngo, Estreya Cohen, Carley Ouellette, Jeffrey I Gold, Deirdre Logan, Laura E Simons, Jennifer N Stinson

JMIR Pediatr Parent 2025 (Apr 07); 8:e63854

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Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

Stefan Liszio, Franziska Bäuerlein, Jens Hildebrand, Carolin van Nahl, Maic Masuch, Oliver Basu

JMIR Res Protoc 2025 (Mar 31); 14:e63098

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Zoom-Delivered Empowered Relief for Chronic Pain: Observational Longitudinal Pilot Study Exploring Feasibility and Pain-Related Outcomes in Patients on Long-Term Opioids

Karlyn A Edwards, Troy C Dildine, Dokyoung S You, Ashley M Herrick, Beth D Darnall, Sean C Mackey, Maisa S Ziadni

JMIR Form Res 2025 (Mar 11); 9:e68292

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Development and Testing of the Kids Hurt App, a Web-Based, Pain Self-Report App for First Nations Youths: Mixed Methods Study

Karlee Francis, Julie Francis, Margot Latimer, Hayley Gould, Shante Blackmore, Emily MacLeod

JMIR Hum Factors 2025 (Mar 03); 12:e48370

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Parental Assessment of Postsurgical Pain in Infants at Home Using Artificial Intelligence–Enabled and Observer-Based Tools: Construct Validity and Clinical Utility Evaluation Study

Fatos Sada, Paola Chivers, Sokol Cecelia, Sejdi Statovci, Kujtim Ukperaj, Jeffery Hughes, Kreshnik Hoti

JMIR Pediatr Parent 2024 (Dec 03); 7:e64669

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Use of Biofeedback-Based Virtual Reality in Pediatric Perioperative and Postoperative Settings: Observational Study

Zandantsetseg Orgil, Anitra Karthic, Nora F Bell, Lisa M Heisterberg, Sara E Williams, Lili Ding, Susmita Kashikar-Zuck, Christopher D King, Vanessa A Olbrecht

JMIR Perioper Med 2024 (Sep 16); 7:e48959

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Exploring Relations Between Unique Patient Characteristics and Virtual Reality Immersion Level on Anxiety and Pain in Patients Undergoing Venipuncture: Secondary Analysis of a Randomized Control Trial

Jeffrey I Gold, Krystal M Akbar, Sandra Avila, Nhat H Ngo, Margaret J Klein

J Med Internet Res 2024 (Jul 01); 26:e53196

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Understanding Adolescents’ Experiences With Menstrual Pain to Inform the User-Centered Design of a Mindfulness-Based App: Mixed Methods Investigation Study

Michelle M Gagnon, Alexandra R Brilz, Nicole M Alberts, Jennifer L Gordon, Tracie L Risling, Jennifer N Stinson

JMIR Pediatr Parent 2024 (Apr 08); 7:e54658

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An Individualized Postoperative Pain Risk Communication Tool for Use in Pediatric Surgery: Co-Design and Usability Evaluation

Michael D Wood, Nicholas C West, Christina Fokkens, Ying Chen, Kent C Loftsgard, Krystal Cardinal, Simon D Whyte, Elodie Portales-Casamar, Matthias Görges

JMIR Pediatr Parent 2023 (Nov 17); 6:e46785

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Exploring User Visions for Modeling mHealth Apps Toward Supporting Patient-Parent-Clinician Collaboration and Shared Decision-making When Treating Adolescent Knee Pain in General Practice: Workshop Study

Simon Kristoffer Johansen, Anne Marie Kanstrup, Kian Haseli, Visti Hildebrandt Stenmo, Janus Laust Thomsen, Michael Skovdal Rathleff

JMIR Hum Factors 2023 (Apr 28); 10:e44462

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Enhancing Exposure Treatment for Youths With Chronic Pain: Co-design and Qualitative Approach

Lea Schemer, Courtney W Hess, Amanda R Van Orden, Kathryn A Birnie, Lauren E Harrison, Julia A Glombiewski, Laura E Simons

J Particip Med 2023 (Mar 09); 15:e41292

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The Clinical Suitability of an Artificial Intelligence–Enabled Pain Assessment Tool for Use in Infants: Feasibility and Usability Evaluation Study

Jeffery David Hughes, Paola Chivers, Kreshnik Hoti

J Med Internet Res 2023 (Feb 13); 25:e41992

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Validation of an Electronic Visual Analog Scale App for Pain Evaluation in Children and Adolescents With Symptomatic Hypermobility: Cross-sectional Study

Muhammad Maarj, Verity Pacey, Louise Tofts, Matthew Clapham, Xavier Gironès Garcia, Andrea Coda

JMIR Pediatr Parent 2022 (Oct 26); 5(4):e41930

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Characterizing User Engagement With a Digital Intervention for Pain Self-management Among Youth With Sickle Cell Disease and Their Caregivers: Subanalysis of a Randomized Controlled Trial

Chitra Lalloo, Fareha Nishat, William Zempsky, Nitya Bakshi, Sherif Badawy, Yeon Joo Ko, Carlton Dampier, Jennifer Stinson, Tonya M Palermo

J Med Internet Res 2022 (Aug 30); 24(8):e40096

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Codevelopment of Implementation Interventions to Support Parent-Led Care for Pain in Infants: Protocol for a Qualitative Descriptive Study

Britney Benoit, Christine Cassidy, Jacqueline van Wijlen, Quinn Correll, Marsha Campbell-Yeo, Sionnach Hendra, Ruth Martin-Misener, Jennifer MacDougall, Ashley Cameron

JMIR Res Protoc 2022 (Aug 05); 11(8):e33770

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The Effectiveness of the Buzzy Device for Pain Relief in Children During Intravenous Injection: Quasirandomized Study

Yen-Hua Cho, Yi-Chien Chiang, Tsung-Lan Chu, Chi-Wen Chang, Chun-Chu Chang, Hsiu-Min Tsai

JMIR Pediatr Parent 2022 (Apr 29); 5(2):e15757

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Distracting Through Procedural Pain and Distress Using Virtual Reality and Guided Imagery in Pediatric, Adolescent, and Young Adult Patients: Randomized Controlled Trial

Jennifer A Hoag, Jeffrey Karst, Kristin Bingen, Akasha Palou-Torres, Ke Yan

J Med Internet Res 2022 (Apr 18); 24(4):e30260

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Use of Virtual Reality in the Reduction of Pain After the Administration of Vaccines Among Children in Primary Care Centers: Protocol for a Randomized Clinical Trial

Mercedes de la Cruz Herrera, Aïna Fuster-Casanovas, Queralt Miró Catalina, Mireia Cigarrán Mensa, Pablo Alcántara Pinillos, Isabel Vilanova Guitart, Sergi Grau Carrión, Josep Vidal-Alaball

JMIR Res Protoc 2022 (Apr 07); 11(4):e35910

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Effectiveness of eHealth and mHealth Interventions Supporting Children and Young People Living With Juvenile Idiopathic Arthritis: Systematic Review and Meta-analysis

Sonia Butler, Dean Sculley, Derek Santos, Antoni Fellas, Xavier Gironès, Davinder Singh-Grewal, Andrea Coda

J Med Internet Res 2022 (Feb 02); 24(2):e30457

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Natural Language Processing and Machine Learning Methods to Characterize Unstructured Patient-Reported Outcomes: Validation Study

Zhaohua Lu, Jin-ah Sim, Jade X Wang, Christopher B Forrest, Kevin R Krull, Deokumar Srivastava, Melissa M Hudson, Leslie L Robison, Justin N Baker, I-Chan Huang

J Med Internet Res 2021 (Nov 03); 23(11):e26777

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