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Glucagon-Like Peptide-1 Receptor Agonists Combined With Personalized Digital Health Care for the Treatment of Metabolic Syndrome in Adults With Obesity: Retrospective Observational Study

Glucagon-Like Peptide-1 Receptor Agonists Combined With Personalized Digital Health Care for the Treatment of Metabolic Syndrome in Adults With Obesity: Retrospective Observational Study

What can be concluded is that GLP outcomes on certain Met S parameters can be enhanced when delivered in a hybrid care model, as demonstrated in previous studies, thereby leading to better outcomes, an important factor considering the cost of GLP treatments.

Hala Zakaria, Hadoun Jabri, Sheikha Alshehhi, Milena Caccelli, Joelle Debs, Yousef Said, Joudy Kattan, Noah Almarzooqi, Ali Hashemi, Ihsan Almarzooqi

Interact J Med Res 2025;14:e63079

Evaluation of a Guided Chatbot Intervention for Young People in Jordan: Feasibility Randomized Controlled Trial

Evaluation of a Guided Chatbot Intervention for Young People in Jordan: Feasibility Randomized Controlled Trial

Although AI-based chatbots better mimic natural conversations, can apply therapeutic techniques dynamically, and learn over time, they are a new technology, and possible risks and challenges with large language models are currently unclear [9]. Rule-based chatbots operate with predefined scripts and pathways and are therefore predictable and allow for standardization of interventions.

Anne Marijn de Graaff, Rand Habashneh, Sarah Fanatseh, Dharani Keyan, Aemal Akhtar, Adnan Abualhaija, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas, Chiara Servili, Mark van Ommeren, Richard Bryant, Kenneth Carswell

JMIR Ment Health 2025;12:e63515

Balancing Between Privacy and Utility for Affect Recognition Using Multitask Learning in Differential Privacy–Added Federated Learning Settings: Quantitative Study

Balancing Between Privacy and Utility for Affect Recognition Using Multitask Learning in Differential Privacy–Added Federated Learning Settings: Quantitative Study

This operation can be modeled by: where N is scaling noise sampled from a specific distribution. In this work, we chose Laplace and Gaussian mechanisms [25] that use L1 and L2 norm sensitivity, respectively. The sensitivity function can be expressed as: Scaling noise can be computed as: Output perturbation satisfies (ϵ,δ)-DP when we properly select the value scaling noise.

Mohamed Benouis, Elisabeth Andre, Yekta Said Can

JMIR Ment Health 2024;11:e60003

Development and Validation of a Machine Learning–Based Early Warning Model for Lichenoid Vulvar Disease: Prediction Model Development Study

Development and Validation of a Machine Learning–Based Early Warning Model for Lichenoid Vulvar Disease: Prediction Model Development Study

LVD is often recurrent, and in the later stage, it can lead to vaginal stenosis, causing dyspareunia and even carrying the risk of carcinoma, which severely impacts the physical and psychological well-being of the patients [4-6]. It is evident that Chinese women are often reluctant to seek medical care from formal health care facilities due to economic, cultural and traditional concept, and other factors.

Jian Meng, Xiaoyu Niu, Can Luo, Yueyue Chen, Qiao Li, Dongmei Wei

J Med Internet Res 2024;26:e55734

Scalable Technology for Adolescents and Youth to Reduce Stress in the Treatment of Common Mental Disorders in Jordan: Protocol for a Randomized Controlled Trial

Scalable Technology for Adolescents and Youth to Reduce Stress in the Treatment of Common Mental Disorders in Jordan: Protocol for a Randomized Controlled Trial

Preliminary studies exploring the effectiveness of chatbots on mental health outcomes are promising [32,33] and suggest they may be a practical way of providing mental health care as they can (1) use existing and widely available software infrastructures, and (2) may increase engagement due to the conversational nature of delivery.

Aemal Akhtar, Anne Marijn de Graaff, Rand Habashneh, Dharani Keyan, Adnan Abualhaija, Sarah Fanatseh, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas, Chiara Servili, Mark van Ommeren, Richard Bryant, Kenneth Carswell

JMIR Res Protoc 2024;13:e54585

Efficient Use of Biological Data in the Web 3.0 Era by Applying Nonfungible Token Technology

Efficient Use of Biological Data in the Web 3.0 Era by Applying Nonfungible Token Technology

It can hold many files that include transaction IDs and detailed history. Therefore, we can store a large number of biomedical and sample data through an NFT [19]. As envisaged by Skalidis et al [20], tagging and converting patient data (medical information, health status, examination results, and consent forms) into an NFT can enhance privacy and ensure data integrity and confidentiality in clinical practice and research.

Guanyi Wang, Chen Chen, Ziyu Jiang, Gang Li, Can Wu, Sheng Li

J Med Internet Res 2024;26:e46160

Association Between Sleep Efficiency Variability and Cognition Among Older Adults: Cross-Sectional Accelerometer Study

Association Between Sleep Efficiency Variability and Cognition Among Older Adults: Cross-Sectional Accelerometer Study

An explicit explanation of how each covariate was defined can be found in Multimedia Appendix 1. Participants with missing data were excluded to enable a complete-case analysis. Participant characteristics were reported using the means and SDs for numeric variables and counts and percentages for categorical variables. We first examined the relationship between mean and day-to-day sleep efficiency variability using the Pearson r correlation coefficient and a scatterplot.

Collin Sakal, Tingyou Li, Juan Li, Can Yang, Xinyue Li

JMIR Aging 2024;7:e54353

Interactive Narrative–Based Digital Health Interventions for Vaccine Communication: Protocol for a Scoping Review

Interactive Narrative–Based Digital Health Interventions for Vaccine Communication: Protocol for a Scoping Review

These factors can result in vaccine hesitancy, a state of decisional ambivalence that manifests as a “delay in acceptance or refusal of vaccination despite availability of vaccination services” [2]. Vaccine hesitancy is blamed for backslides in vaccination coverage in high-income countries (eg, in Europe and the Americas), where issues with vaccine availability are less of a factor in suboptimal vaccine uptake [3].

Ahmed Haji Said, Kate Winskell, Robert A Bednarczyk, Erin E Reardon, Lavanya Vasudevan

JMIR Res Protoc 2024;13:e51137

Digital Phenotyping for Monitoring Mental Disorders: Systematic Review

Digital Phenotyping for Monitoring Mental Disorders: Systematic Review

All this information can then be analyzed using big data processing methods, such as deep learning and machine learning algorithms, aimed at classifying mental health status or predicting symptomatic worsening [3] (Figure 1).

Pasquale Bufano, Marco Laurino, Sara Said, Alessandro Tognetti, Danilo Menicucci

J Med Internet Res 2023;25:e46778