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Ameliorating Racial Disparities in HIV Prevention via a Nurse-Led, AI-Enhanced Program for Pre-Exposure Prophylaxis Utilization Among Black Cisgender Women: Protocol for a Mixed Methods Study

Ameliorating Racial Disparities in HIV Prevention via a Nurse-Led, AI-Enhanced Program for Pre-Exposure Prophylaxis Utilization Among Black Cisgender Women: Protocol for a Mixed Methods Study

HIV pre-exposure prophylaxis (Pr EP) is a safe and proven biomedical strategy to prevent HIV transmission among cisgender women [1-3]. However, Black cisgender women remain underrepresented throughout the Pr EP care continuum compared to their White counterparts [4,5].

Chen Zhang, Mitchell Wharton, Yu Liu

JMIR Res Protoc 2024;13:e59975

User Experience of Persons Using Ingestible Sensor–Enabled Pre-Exposure Prophylaxis to Prevent HIV Infection: Cross-Sectional Survey Study

User Experience of Persons Using Ingestible Sensor–Enabled Pre-Exposure Prophylaxis to Prevent HIV Infection: Cross-Sectional Survey Study

IS-enabled tenofovir disoproxil fumarate plus emtricitabine (IS-Truvada) with the DHFS has recently been deployed to capture medication adherence behavior in persons starting oral pre-exposure prophylaxis (Pr EP) [7]. This study confirmed that the DHFS is highly accurate, providing valid measures of ingestion with 99.3% (95% CI 97.2%-100%) reliability versus direct observation, similar to findings in a population of patients with tuberculosis (TB) [6,7].

Sara Browne, Anya Umlauf, David J Moore, Constance A Benson, Florin Vaida

JMIR Mhealth Uhealth 2024;12:e53596

Health Information on Pre-Exposure Prophylaxis From Search Engines and Twitter: Readability Analysis

Health Information on Pre-Exposure Prophylaxis From Search Engines and Twitter: Readability Analysis

Pre-exposure prophylaxis (Pr EP) is proven to prevent HIV infections [1-3], and using Pr EP to prevent new HIV infections among vulnerable populations has been identified as a critical strategy in the Ending the HIV Epidemic initiative [4]. Pr EP use increased more than 10-fold in the United States in just 5 years after its approval in 2012 [5].

Albert Park, Fatima Sayed, Patrick Robinson, Latesha Elopre, Yaorong Ge, Shaoyu Li, Christian Grov, Patrick Sean Sullivan

JMIR Public Health Surveill 2023;9:e48630

The Characteristics, Uses, and Biases of Studies Related to Malignancies Using Google Trends: Systematic Review

The Characteristics, Uses, and Biases of Studies Related to Malignancies Using Google Trends: Systematic Review

We collected the following details: title, DOI code, authors’ countries, year of publication, aims, aims classification, study category (prophylaxis, awareness month, celebrity death, COVID-19, and others), malignancies considered, analysis of topics or search terms, regions and period analyzed, statistical reproducibility method used, confrontation of GT results with real-world data (eg, with epidemiological data), principal findings, and sensitivity analysis.

Mikołaj Kamiński, Jakub Czarny, Piotr Skrzypczak, Krzysztof Sienicki, Magdalena Roszak

J Med Internet Res 2023;25:e47582

Health Information From Web Search Engines and Virtual Assistants About Pre-Exposure Prophylaxis for HIV Prevention in Adolescents and Young Adults: Content Analysis

Health Information From Web Search Engines and Virtual Assistants About Pre-Exposure Prophylaxis for HIV Prevention in Adolescents and Young Adults: Content Analysis

Pre-exposure prophylaxis (Pr EP) is an effective daily prevention method and should be considered for use by HIV-negative populations at higher risk of HIV [3]. When taken as prescribed, Pr EP can offer almost complete protection against HIV; however, previous studies have shown that Pr EP uptake is lower in higher risk populations [4,5]. Barriers to Pr EP uptake include limited awareness and limited access as a result of Pr EP marketing and additional socioeconomic challenges, respectively [5].

Kaja Darien, Susan Lee, Kayla Knowles, Sarah Wood, Miriam D Langer, Nellie Lazar, Nadia Dowshen

JMIR Pediatr Parent 2023;6:e41806

A Transgender Chatbot (Amanda Selfie) to Create Pre-exposure Prophylaxis Demand Among Adolescents in Brazil: Assessment of Acceptability, Functionality, Usability, and Results

A Transgender Chatbot (Amanda Selfie) to Create Pre-exposure Prophylaxis Demand Among Adolescents in Brazil: Assessment of Acceptability, Functionality, Usability, and Results

In addition, adolescent men who have sex with men (AMSM) have less knowledge and are less willing to use new HIV preventive methods, such as pre-exposure prophylaxis (Pr EP), compared with older MSM [5]. This reality has demonstrated the importance of developing HIV prevention strategies that are more consistent with the values and practices of younger generations, emphasizing the use of digital technologies and social media [6-8].

Paula Massa, Dulce Aurélia de Souza Ferraz, Laio Magno, Ana Paula Silva, Marília Greco, Inês Dourado, Alexandre Grangeiro

J Med Internet Res 2023;25:e41881

Findings From the Step Up, Test Up Study of an Electronic Screening and Brief Intervention for Alcohol Misuse in Adolescents and Young Adults Presenting for HIV Testing: Randomized Controlled Efficacy Trial

Findings From the Step Up, Test Up Study of an Electronic Screening and Brief Intervention for Alcohol Misuse in Adolescents and Young Adults Presenting for HIV Testing: Randomized Controlled Efficacy Trial

Along with routine condom use and pre-exposure prophylaxis (Pr EP), addressing alcohol and other drug (AOD) use are among the most modifiable individual-level factors for the prevention of HIV and sexually transmitted infections (STIs). Although there are many structural factors including racism, stigma, and poverty that contribute to the dynamics of HIV infection, prevention strategies have often focused on individual or personal-level factors.

Niranjan S Karnik, Lisa M Kuhns, Anna L Hotton, Natascha Del Vecchio, Moira McNulty, John Schneider, Geri Donenberg, Kristin Keglovitz Baker, Rose Diskin, Abigail Muldoon, Juan Rivera, Faith Summersett Williams, Robert Garofalo

JMIR Ment Health 2023;10:e43653

Evaluation of the Care Pathway in the Context of the Dispensing of Emicizumab (Hemlibra) in Community Pharmacies in France: Protocol for a Cross-sectional Study Based on the Kirkpatrick Model

Evaluation of the Care Pathway in the Context of the Dispensing of Emicizumab (Hemlibra) in Community Pharmacies in France: Protocol for a Cross-sectional Study Based on the Kirkpatrick Model

It can be prescribed for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adults and children of all ages, newborn and older, with hemophilia A, with or without treatment with an FVIII inhibitor [13-15]. In 2019, emicizumab received marketing authorization for severe hemophilia A with or without an inhibitor in Europe [16]. This drug was initially available only from French hospital pharmacies, but from June 15, 2021, it has also been available in community pharmacies.

Laurie Fraticelli, Julie Freyssenge, Emilie Promé-Combel, Eléonore Agnellet, Yesim Dargaud, Valérie Chamouard

JMIR Res Protoc 2023;12:e43091

Using PrEP and Doing it for Ourselves (UPDOs Protective Styles), a Web-Based Salon Intervention to Improve Uptake of Pre-exposure Prophylaxis Among Black Women: Protocol for a Pilot Feasibility Study

Using PrEP and Doing it for Ourselves (UPDOs Protective Styles), a Web-Based Salon Intervention to Improve Uptake of Pre-exposure Prophylaxis Among Black Women: Protocol for a Pilot Feasibility Study

Pre-exposure prophylaxis (Pr EP), taken as prescribed, is an effective HIV prevention strategy, yet uptake remains low among populations at risk for HIV in the US, especially Black women living in the US South [1]. Black women in the US comprise 13% of all women but account for over half (55%) of new HIV infections among women [2], and individuals living in the southern states are at the highest risk of acquiring HIV.

Schenita D Randolph, Ragan Johnson, Allison Johnson, Lana Keusch

JMIR Res Protoc 2022;11(8):e34556

Integrating and Disseminating Pre-Exposure Prophylaxis (PrEP) Screening and Dispensing for Black Men Who Have Sex With Men in Atlanta, Georgia: Protocol for Community Pharmacies

Integrating and Disseminating Pre-Exposure Prophylaxis (PrEP) Screening and Dispensing for Black Men Who Have Sex With Men in Atlanta, Georgia: Protocol for Community Pharmacies

Pre-exposure prophylaxis (Pr EP) is the single most effective HIV prevention strategy, yet it is underutilized among BMSM. When taken every day, Pr EP reduces the risk of HIV infection by approximately 99% among MSM, yet profound racial disparities in the uptake of Pr EP persist [4-6]. Studies estimate that 48-70% of BMSM are willing to use Pr EP [7,8]. Yet, uptake among Black individuals is only about 10% [9].

Natalie D Crawford, Kristin R V Harrington, Daniel I Alohan, Patrick S Sullivan, David P Holland, Donald G Klepser, Alvan Quamina, Aaron J Siegler, Henry N Young

JMIR Res Protoc 2022;11(2):e35590