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Gamified Adaptive Approach Bias Modification in Individuals With Methamphetamine Use History From Communities in Sichuan: Pilot Randomized Controlled Trial

Gamified Adaptive Approach Bias Modification in Individuals With Methamphetamine Use History From Communities in Sichuan: Pilot Randomized Controlled Trial

Participants were recruited from 12 community-based rehabilitation centers in Sichuan, China, all having a history of methamphetamine use and undergoing community-based rehabilitation. Participants were individuals aged between 18 and 55 years with a history of methamphetamine use for at least 1 year. The diagnosis of methamphetamine use disorder was confirmed based on community rehabilitation center records and self-reports.

Danlin Shen, Jianping Jiao, Liqun Zhang, Yanru Liu, Xiang Liu, Yuanhui Li, Tianjiao Zhang, Dai Li, Wei Hao

JMIR Serious Games 2025;13:e56978

Identification of Behavioral, Clinical, and Psychological Antecedents of Acute Stimulant Poisoning: Development and Implementation of a Mixed Methods Psychological Autopsy Study

Identification of Behavioral, Clinical, and Psychological Antecedents of Acute Stimulant Poisoning: Development and Implementation of a Mixed Methods Psychological Autopsy Study

From 2015 to 2022, poisoning deaths in the United States attributed to cocaine or methamphetamine increased 4- and 6-fold, respectively [2]. This increase in mortality, largely driven by deaths also involving fentanyl, a potent synthetic opioid, has been referred to as the “fourth wave” of the overdose crisis [3-6].

Marley Antolin Muñiz, Vanessa M McMahan, Xochitl Luna Marti, Sarah Brennan, Sophia Tavasieff, Luke N Rodda, James Knoll, Phillip O Coffin

JMIR Form Res 2025;9:e64873

Structural Influences on Methamphetamine Use Among Black Sexual Minority Men (HISTORY Study): Protocol for a Longitudinal Cohort Study

Structural Influences on Methamphetamine Use Among Black Sexual Minority Men (HISTORY Study): Protocol for a Longitudinal Cohort Study

Methamphetamine use is increasingly common in the United States. Among the total US population of individuals aged 12 years and older, 1% (or 2.7 million people) reported past-year methamphetamine use in 2022, 66.7% (or 1.8 million) of whom met the criteria for methamphetamine use disorder [1]. These represent the highest rates in an upward trend in past-year methamphetamine use and methamphetamine use disorder, according to the annual National Survey on Drug Use and Health [2].

Samuel C O Opara, Sabriya L Linton, Brian W Weir, Natalie D Crawford, David P Holland, Antonio Newman Jr, McKinsey Bullock, Marcus O Reed, Srija Dutta, Kamini Doraivelu, Charles Stephens, Justin C Smith, Yeeli Mui, Sophia A Hussen

JMIR Res Protoc 2024;13:e63761

Effect of a Smartphone App (S-Check) on Actual and Intended Help-Seeking and Motivation to Change Methamphetamine Use Among Adult Consumers of Methamphetamine in Australia: Randomized Waitlist-Controlled Trial

Effect of a Smartphone App (S-Check) on Actual and Intended Help-Seeking and Motivation to Change Methamphetamine Use Among Adult Consumers of Methamphetamine in Australia: Randomized Waitlist-Controlled Trial

Access to treatment is associated with more positive outcomes [8], but despite this, a gap of up to 10 years has been shown between the onset of problems related to methamphetamine use and presentation to health services for assistance [9]. Delays in access to health services can be due to a perception of “nonproblematic” methamphetamine use among people with methamphetamine use disorder [10,11].

Krista J Siefried, Florence Bascombe, Brendan Clifford, Zhixin Liu, Peter Middleton, Frances Kay-Lambkin, Jack Freestone, Daniel Herman, Michael Millard, Maureen Steele, Liam Acheson, Carl Moller, Nicky Bath, Nadine Ezard

JMIR Mhealth Uhealth 2024;12:e55663

Analysis of Wastewater Samples to Explore Community Substance Use in the United States: Pilot Correlative and Machine Learning Study

Analysis of Wastewater Samples to Explore Community Substance Use in the United States: Pilot Correlative and Machine Learning Study

The sampler extract was quantitatively transferred to glass culture tubes using additional methanol and spiked with isotope-labeled internal standards (250 µL of carbamazepine-13 C6, methamphetamine-d8, MDMA-d5, and MDA-d5, sulfamethazine-13 C6, caffeine-13 C3, morphine-d3, methadone-d3, oxycodone-d6, hydrocodone-d6, and temazepam-d5).

Marie A Severson, Sathaporn Onanong, Alexandra Dolezal, Shannon L Bartelt-Hunt, Daniel D Snow, Lisa M McFadden

JMIR Form Res 2023;7:e45353

Motivational Enhancement Interventions to Increase Pre-Exposure Prophylaxis Use in Sexual Minority Men Who Use Stimulants: Protocol for a Pilot Sequential Multiple Assignment Randomized Trial

Motivational Enhancement Interventions to Increase Pre-Exposure Prophylaxis Use in Sexual Minority Men Who Use Stimulants: Protocol for a Pilot Sequential Multiple Assignment Randomized Trial

Over and above these profound racial disparities, there is a resurgent epidemic of methamphetamine use among sexual minority men that is disproportionately affecting Black and Latino sexual minority men [9-12]. Although methamphetamine use appeared to decline somewhat after significant public health attention in the early- and mid-2000s [13,14], it is again on the rise [13,15-19].

Leah Davis-Ewart, Christian Grov, Rachel Verhagen, Jennifer Manuel, Michael Viamonte, Samantha Dilworth, Nicole O'Dell, Omar Valentin, Sidney Carr, Emily Cherenack, Chelsea Henderson, Susanne Doblecki-Lewis, Inbal Nahum-Shani, Adam W Carrico

JMIR Res Protoc 2023;12:e48459

Corpus-Based Discourse Analysis of a Reddit Community of Users of Crystal Methamphetamine: Mixed Methods Study

Corpus-Based Discourse Analysis of a Reddit Community of Users of Crystal Methamphetamine: Mixed Methods Study

Methamphetamine is a highly addictive stimulant that affects the central nervous system. Crystal methamphetamine (or “crystal meth”) is a form of the drug resembling glass fragments or shiny bluish-white rocks that can be taken through smoking, swallowing (pill), snorting, or injecting the powder once it has been dissolved in water or alcohol [1]. This study examines the social construction of identity among people who use methamphetamine.

Andrew Lustig, Gavin Brookes

JMIR Infodemiology 2023;3:e48189

Evaluation of a Digital Health Initiative in Illicit Substance Use: Cross-sectional Survey Study

Evaluation of a Digital Health Initiative in Illicit Substance Use: Cross-sectional Survey Study

Internationally, there continues to be a widespread concern about the use of methamphetamine, particularly with respect to the most potent form, crystal methamphetamine. Crystal methamphetamine produces stronger and longer-lasting effects than other forms of methamphetamine, thereby increasing the risk of serious long-term health issues, including dependence [1,2].

Steph Kershaw, Louise Birrell, Hannah Deen, Nicola C Newton, Lexine A Stapinski, Katrina E Champion, Frances Kay-Lambkin, Maree Teesson, Cath Chapman

J Med Internet Res 2021;23(8):e29026

 A Theory-Based mHealth Intervention (Getting Off) for Methamphetamine-Using Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial

A Theory-Based mHealth Intervention (Getting Off) for Methamphetamine-Using Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial

Men who have sex with men (MSM) have elevated rates of methamphetamine (meth) use relative to non-MSM [1-3], as meth use is deeply integrated into the sexual identities and sexual behaviors of MSM in the United States [3-7] and permeates the venues most often associated with high-risk sexual behaviors among MSM [8-10].

Cathy J Reback, Jesse B Fletcher, Raymond P Mata

JMIR Res Protoc 2021;10(2):e22572