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A Digital Home-Based Health Care Center for Remote Monitoring of Side Effects During Breast Cancer Therapy: Prospective, Single-Arm, Monocentric Feasibility Study

A Digital Home-Based Health Care Center for Remote Monitoring of Side Effects During Breast Cancer Therapy: Prospective, Single-Arm, Monocentric Feasibility Study

(B) Patients received a large case with (C) integrated charging for all devices, (D) specifically designed for at-home use, (E,F) or a smaller and lighter case with foam material to securely hold all devices. (G) The associated SMILER.one app featured a home screen displaying the trial tasks, (H) a data archive for storing all collected data, and (I) functionality for collecting and visualizing specific parameters such as WBC counts. ECG: electrocardiogram; Qo L: quality of life; WBC: white blood cell.

Hanna Huebner, Lena A Wurmthaler, Chloë Goossens, Mathias Ernst, Alexander Mocker, Annika Krückel, Maximilian Kallert, Jürgen Geck, Milena Limpert, Katharina Seitz, Matthias Ruebner, Philipp Kreis, Felix Heindl, Manuel Hörner, Bernhard Volz, Eduard Roth, Carolin C Hack, Matthias W Beckmann, Sabrina Uhrig, Peter A Fasching

JMIR Cancer 2025;11:e64083

The Comprehensive Adaptive Multisite Prevention of University Student Suicide Trial: Protocol for a Randomized Controlled Trial

The Comprehensive Adaptive Multisite Prevention of University Student Suicide Trial: Protocol for a Randomized Controlled Trial

The primary goal of aim 1 is to identify the most effective ATS among the 4 embedded strategies (A+B, A+C, D+E, or D+F, as shown in Table 2) that leads to the greatest reduction in STB. This aim focuses on finding the best-performing ATS rather than testing a hypothesis. The sample size of 480 was found to ensure an 80% probability of correctly identifying the ATS with the lowest mean outcome, assuming that such a strategy exists.

Kyla Blalock, Jacqueline Pistorello, Shireen L Rizvi, John R Seeley, Francesca Kassing, James Sinclair, Linda A Oshin, Robert J Gallop, Cassidy M Fry, Ted Snyderman, David A Jobes, Jennifer Crumlish, Hannah R Krall, Susan Stadelman, Filiz Gözenman-Sapin, Kate Davies, David Steele, David B Goldston, Scott N Compton

JMIR Res Protoc 2025;14:e68441