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Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Summary of study activities. a Hb A1c: hemoglobin A1c. b CRP: C-reactive protein. c OGTT: oral glucose tolerance test. At the first visit, a full medical history will be taken by a trained clinician including past medical history and surgical history. Outcomes of previous pregnancies will be recorded including outcome of the pregnancy, gestation, pregnancy complications, and (if relevant) birthweight and neonatal complications. Current medications including dose, and dosing schedule will be recorded.

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study

We examined all contexts along the data pipeline, from population-level breast cancer screening to diagnostic biopsies and surgical treatments, clinical pathology, and specimen accessioning through the biobanking platform, where it may be stored for future use in –80 °C freezers or distributed fresh for next-generation biobanking applications such as patient-derived organoids, multi-omics, and high-throughput testing.

William Sanchez, Ananya Dewan, Eve Budd, M Eifler, Robert C Miller, Jeffery Kahn, Mario Macis, Marielle Gross

JMIR Bioinform Biotech 2025;6:e70463

Identification of Patients With Congestive Heart Failure From the Electronic Health Records of Two Hospitals: Retrospective Study

Identification of Patients With Congestive Heart Failure From the Electronic Health Records of Two Hospitals: Retrospective Study

(C) and (D) Performance of training on BIDMC data and testing on MGH data. AUPRC: area under the precision-recall curve; AUROC: area under the receiver operating characteristic curve; BIDMC: Beth Israel Deaconess Medical Center; MGH: Mass General Hospital; PR: precision-recall; ROC: receiver operating characteristic. Logistic regression coefficients from using the model trained with notes, ICDa codes, and medications. Unexpected results are discussed in the Error Analysis section.

Daniel Sumsion, Elijah Davis, Marta Fernandes, Ruoqi Wei, Rebecca Milde, Jet Malou Veltink, Wan-Yee Kong, Yiwen Xiong, Samvrit Rao, Tara Westover, Lydia Petersen, Niels Turley, Arjun Singh, Stephanie Buss, Shibani Mukerji, Sahar Zafar, Sudeshna Das, Valdery Moura Junior, Manohar Ghanta, Aditya Gupta, Jennifer Kim, Katie Stone, Emmanuel Mignot, Dennis Hwang, Lynn Marie Trotti, Gari D Clifford, Umakanth Katwa, Robert Thomas, M Brandon Westover, Haoqi Sun

JMIR Med Inform 2025;13:e64113

Conversion of Sensitive Data to the Observational Medical Outcomes Partnership Common Data Model: Protocol for the Development and Use of Carrot

Conversion of Sensitive Data to the Observational Medical Outcomes Partnership Common Data Model: Protocol for the Development and Use of Carrot

(C) The OMOP standardized deidentified dataset. OMOP: Observational Medical Outcomes Partnership. Each data partner remains responsible for the management of their data, including generating a pseudonymized and deidentified extract. There are some preprocessing steps that they must perform to use the tool, but we have minimized the workload on each data partner.

Samuel Cox, Erum Masood, Vasiliki Panagi, Calum Macdonald, Gordon Milligan, Scott Horban, Roberto Santos, Chris Hall, Daniel Lea, Simon Tarr, Shahzad Mumtaz, Emeka Akashili, Andy Rae, Esmond Urwin, Christian Cole, Aziz Sheikh, Emily Jefferson, Philip Roy Quinlan

JMIR Res Protoc 2025;14:e60917