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Evaluation of an Online-Based Self-Help Program for Patients With Panic Disorder: Randomized Controlled Trial

Evaluation of an Online-Based Self-Help Program for Patients With Panic Disorder: Randomized Controlled Trial

CBT targets fear and avoidance behavior by psychoeducation, exposure therapy, cognitive restructuring, mindfulness, and acceptance interventions leading to large effect sizes compared with a waitlist group (hedges g=0.96; [12]). Also, effects remain superior to treatment as usual for 6 months of follow-up [13]. Psychopharmacology yields small to moderate effect sizes in comparison to placebo and similar to CBT [14].

Christopher Lalk, Teresa Väth, Sofie Hanraths, Luise Pruessner, Christina Timm, Steffen Hartmann, Sven Barnow, Julian Rubel

J Med Internet Res 2025;27:e54062

Acceptability of a Web-Based Health App (PortfolioDiet.app) to Translate a Nutrition Therapy for Cardiovascular Disease in High-Risk Adults: Mixed Methods Randomized Ancillary Pilot Study

Acceptability of a Web-Based Health App (PortfolioDiet.app) to Translate a Nutrition Therapy for Cardiovascular Disease in High-Risk Adults: Mixed Methods Randomized Ancillary Pilot Study

Portfolio Diet.app dashboard with key features highlighted, top to bottom: (A) learn tab that has recipes, tipsheets, and videos; (B) daily average Portfolio Diet Score per month; (C) star rewards, a form of reward for logging into the app and for completing the question of the week; (D) current day total Portfolio Diet Score; (E) specific daily messages related to goals; (F) personal favorite meals for easy tracking; (G) subcategory Portfolio Diet Scores with daily targets of 5 points; (H) progress-tracking

Meaghan E Kavanagh, Laura Chiavaroli, Selina M Quibrantar, Gabrielle Viscardi, Kimberly Ramboanga, Natalie Amlin, Melanie Paquette, Sandhya Sahye-Pudaruth, Darshna Patel, Shannan M Grant, Andrea J Glenn, Sabrina Ayoub-Charette, Andreea Zurbau, Robert G Josse, Vasanti S Malik, Cyril W C Kendall, David J A Jenkins, John L Sievenpiper

JMIR Cardio 2025;9:e58124

Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial

Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial

The tubes are centrifuged at 5000 g for 5 minutes at room temperature to pellet the powdered hair. The entire amount (~1 m L) of supernatant is transferred to a clean microcentrifuge tube, and the methanol is removed by evaporation using a stream of air for 6-8 hours at room temperature. The cortisol extract is reconstituted in 100 μL of Salimetric immunoassay cortisol analysis diluent buffer. Samples are assayed in duplicate inter- and intra-assay coefficients of calculated variation.

Kathy D Wright, Ingrid K Richards Adams, Nathan P Helsabeck, Karen M Rose, Karen O Moss, Donya Nemati, Navia Palmer, Bohyun Kim, Sunita Pokhrel Bhattarai, Christopher Nguyen, Daniel Addison, Maryanna D Klatt

JMIR Res Protoc 2025;14:e66975

Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial

Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial

Sample size calculation was undertaken using procedures provided by the software program G*Power 3 [37]. As per our statistical consultant, the calculation was undertaken to determine adequate power in the determination of the potential effects of the intervention (aim 3), in which a repeated-measures ANOVA with a within-between interaction would be the statistical test used.

Saima Ahmed, Christine Maheu, Walter Gotlieb, Gerald Batist, Carmen G Loiselle

JMIR Res Protoc 2025;14:e55475