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Improving Early Dementia Detection Among Diverse Older Adults With Cognitive Concerns With the 5-Cog Paradigm: Protocol for a Hybrid Effectiveness-Implementation Clinical Trial

Rachel Beth Rosansky Chalmer, Emmeline Ayers, Erica F Weiss, Nicole R Fowler, Andrew Telzak, Diana Summanwar, Jessica Zwerling, Cuiling Wang, Huiping Xu, Richard J Holden, Kevin Fiori, Dustin D French, Celeste Nsubayi, Asif Ansari, Paul Dexter, Anna Higbie, Pratibha Yadav, James M Walker, Harrshavasan Congivaram, Dristi Adhikari, Mairim Melecio-Vazquez, Malaz Boustani, Joe Verghese

JMIR Res Protoc 2025;14:e60471

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Assessment and Intervention for Diabetes Distress in Primary Care Using Clinical and Technological Interventions: Protocol for a Single-Arm Pilot Trial

Marisa Kostiuk, Susan L Moore, E Seth Kramer, Joshua Felton Gilens, Ashwin Sarwal, David Saxon, John F Thomas, Tamara K Oser

JMIR Res Protoc 2025;14:e62916

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Development of a Framework for Youth- and Family-Specific Engagement in Research: Proposal for a Scoping Review and Qualitative Descriptive Study

Sarah E P Munce, Clementine Jarrett, Vjura Senthilnathan, Dorothy Luong, Brooke Allemang, Katherine Bailey, Elaine Biddiss, Maria T Britto, Francine Buchanan, Christine Cassidy, Andrea Cross, Jessie Cunningham, Gina Dimitropoulos, Scott E Hadland, Monika Kastner, Tieghan Killackey, Kristina Kokorelias, Colin Macarthur, Samantha Micsinszki, Chavon Niles, F Virginia Wright, Alene Toulany

JMIR Res Protoc 2025;14:e65733

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Glucagon-Like Peptide-1 Receptor Agonists Combined With Personalized Digital Health Care for the Treatment of Metabolic Syndrome in Adults With Obesity: Retrospective Observational Study

Hala Zakaria, Hadoun Jabri, Sheikha Alshehhi, Milena Caccelli, Joelle Debs, Yousef Said, Joudy Kattan, Noah Almarzooqi, Ali Hashemi, Ihsan Almarzooqi

Interact J Med Res 2025;14:e63079

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Unintended Prolonged Opioid Use: Protocol for a Case-Controlled Trial

W Michael Hooten, Darin J Erickson, Marek Chawarski, Natalie A Scholz, Jennifer F Waljee, Chad M Brummett, Molly M Jeffery

JMIR Res Protoc 2025;14:e72032

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A Technology System to Help People With Multiple Disabilities Increase Contact With Objects and Control Environmental Stimulation: Single-Case Research Design

The study complied with the 1964 Helsinki Declaration and its later amendments and was approved by the Ethics Committee of the Lega F. D’Oro, Osimo (AN), Italy (P030820241). Figures 2 reports the data for Liam, Hallie, Logan, and Kali and Figure 3 reports the data for Harper, Jacob, Millie, and Isabel over the different phases of the study. Each data point represents the mean frequency of responses per session over a block (group) of sessions.

Giulio E Lancioni, Gloria Alberti, Chiara Filippini, Nirbhay N Singh, Mark F O'Reilly, Jeff Sigafoos, Valeria Chiariello, Oriana Troccoli