TY - JOUR AU - Wshah, Safwan AU - Skalka, Christian AU - Price, Matthew PY - 2019 DA - 2019/07/22 TI - Predicting Posttraumatic Stress Disorder Risk: A Machine Learning Approach JO - JMIR Ment Health SP - e13946 VL - 6 IS - 7 KW - PTSD KW - machine learning KW - predictive algorithms AB - Background: A majority of adults in the United States are exposed to a potentially traumatic event but only a handful go on to develop impairing mental health conditions such as posttraumatic stress disorder (PTSD). Objective: Identifying those at elevated risk shortly after trauma exposure is a clinical challenge. The aim of this study was to develop computational methods to more effectively identify at-risk patients and, thereby, support better early interventions. Methods: We proposed machine learning (ML) induction of models to automatically predict elevated PTSD symptoms in patients 1 month after a trauma, using self-reported symptoms from data collected via smartphones. Results: We show that an ensemble model accurately predicts elevated PTSD symptoms, with an area under the curve (AUC) of .85, using a bag of support vector machines, naive Bayes, logistic regression, and random forest algorithms. Furthermore, we show that only 7 self-reported items (features) are needed to obtain this AUC. Most importantly, we show that accurate predictions can be made 10 to 20 days posttrauma. Conclusions: These results suggest that simple smartphone-based patient surveys, coupled with automated analysis using ML-trained models, can identify those at risk for developing elevated PTSD symptoms and thus target them for early intervention. SN - 2368-7959 UR - http://mental.jmir.org/2019/7/e13946/ UR - https://doi.org/10.2196/13946 UR - http://www.ncbi.nlm.nih.gov/pubmed/31333201 DO - 10.2196/13946 ID - info:doi/10.2196/13946 ER -