TY  - JOUR
AU  - Cochran, Amy
AU  - Maronge, Jacob M
AU  - Victory, Amanda
AU  - Hoel, Sydney
AU  - McInnis, Melvin G
AU  - Thomas, Emily BK
PY  - 2023
DA  - 2023/4/20
TI  - Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial
JO  - JMIR Ment Health
SP  - e43164
VL  - 10
KW  - acceptance and commitment therapy
KW  - bipolar disorder
KW  - mobile applications
KW  - randomized controlled trials
KW  - micro-randomized trial
KW  - precision medicine
KW  - mindfulness
AB  - Background: Mobile interventions promise to fill in gaps in care with their broad reach and flexible delivery. Objective: Our goal was to investigate delivery of a mobile version of acceptance and commitment therapy (ACT) for individuals with bipolar disorder (BP). Methods: Individuals with BP (n=30) participated in a 6-week microrandomized trial. Twice daily, participants logged symptoms in the app and were repeatedly randomized (or not) to receive an ACT intervention. Self-reported behavior and mood were measured as the energy devoted to moving toward valued domains or away from difficult emotions and with depressive d and manic m scores from the digital survey of mood in BP survey (digiBP). Results: Participants completed an average of 66% of in-app assessments. Interventions did not significantly impact the average toward energy or away energy but did significantly increase the average manic score m (P=.008) and depressive score d (P=.02). This was driven by increased fidgeting and irritability and interventions focused on increasing awareness of internal experiences. Conclusions: The findings of the study do not support a larger study on the mobile ACT in BP but have significant implications for future studies seeking mobile therapy for individuals with BP. Trial Registration: ClinicalTrials.gov NCT04098497; https://clinicaltrials.gov/ct2/show/NCT04098497 
SN  - 2368-7959
UR  - https://mental.jmir.org/2023/1/e43164
UR  - https://doi.org/10.2196/43164
UR  - http://www.ncbi.nlm.nih.gov/pubmed/37079363
DO  - 10.2196/43164
ID  - info:doi/10.2196/43164
ER  -