%0 Journal Article %@ 2368-7959 %I JMIR Publications %V 11 %N %P e52790 %T Effectiveness of One Videoconference-Based Exposure and Response Prevention Session at Home in Adjunction to Inpatient Treatment in Persons With Obsessive-Compulsive Disorder: Nonrandomized Study %A Voderholzer,Ulrich %A Meule,Adrian %A Koch,Stefan %A Pfeuffer,Simone %A Netter,Anna-Lena %A Lehr,Dirk %A Zisler,Eva Maria %+ Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nußbaumstraße 7, Munich, 80336, Germany, 49 15205886528, Eva.Zisler@med.uni-muenchen.de %K obsessive-compulsive disorder %K videoconference-based treatment %K therapy %K exposure %K response prevention %K OCD %K prevention %K inpatient %K video %K videoconference %K therapist %K therapists %K mood %K positive mood %K environment %K clinical setting %D 2024 %7 13.3.2024 %9 Original Paper %J JMIR Ment Health %G English %X Background: Therapist-guided exposure and response prevention (ERP) for the treatment of obsessive-compulsive disorder (OCD) is frequently conducted within clinical settings but rarely at places where patients are usually confronted with OCD symptom-provoking situations in daily life (eg, at home). Objective: This study aimed to investigate patients’ views on 1 ERP session at home via videoconference and its impact on treatment outcome. Methods: A total of 64 inpatients with OCD received 1 session of therapist-guided videoconference-based ERP at home in adjunction to a multimodal inpatient treatment between 2015 and 2020. Results: Compared with 64 age- and sex-matched controls who received a multimodal inpatient treatment without 1 session of videoconference-based ERP at home, patients who received 1 session of videoconference-based ERP in adjunction to a multimodal inpatient treatment showed stronger reductions in OCD symptom severity from admission to discharge. Before the videoconference-based ERP session, patients reported high rationale credibility and treatment expectancy. After the videoconference-based ERP session, patients reported medium-to-high positive mood as well as depth and smoothness of the session, and they perceived the working alliance as high. Conclusions: Results highlight the importance of administering therapist-guided ERP sessions in patients’ natural environment to enhance treatment response in OCD. Videoconference-based ERP as add-on to treatment as usual is, therefore, a promising approach to facilitate the application of ERP in patients’ natural environment and foster the generalization of ERP conducted in clinical settings. %M 38477970 %R 10.2196/52790 %U https://mental.jmir.org/2024/1/e52790 %U https://doi.org/10.2196/52790 %U http://www.ncbi.nlm.nih.gov/pubmed/38477970