%0 Journal Article
%@ 2368-7959
%I JMIR Publications
%V 10
%N 
%P e43164
%T Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial
%A Cochran,Amy
%A Maronge,Jacob M
%A Victory,Amanda
%A Hoel,Sydney
%A McInnis,Melvin G
%A Thomas,Emily BK
%+ Department of Population Health Sciences, University of Wisconsin Madison, 610 Walnut Street, Madison, WI, 53726, United States, 1 608 262 0772, cochran4@wisc.edu
%K acceptance and commitment therapy
%K bipolar disorder
%K mobile applications
%K randomized controlled trials
%K micro-randomized trial
%K precision medicine
%K mindfulness
%D 2023
%7 20.4.2023
%9 Original Paper
%J JMIR Ment Health
%G English
%X Background: Mobile interventions promise to fill in gaps in care with their broad reach and flexible delivery. Objective: Our goal was to investigate delivery of a mobile version of acceptance and commitment therapy (ACT) for individuals with bipolar disorder (BP). Methods: Individuals with BP (n=30) participated in a 6-week microrandomized trial. Twice daily, participants logged symptoms in the app and were repeatedly randomized (or not) to receive an ACT intervention. Self-reported behavior and mood were measured as the energy devoted to moving toward valued domains or away from difficult emotions and with depressive d and manic m scores from the digital survey of mood in BP survey (digiBP). Results: Participants completed an average of 66% of in-app assessments. Interventions did not significantly impact the average toward energy or away energy but did significantly increase the average manic score m (P=.008) and depressive score d (P=.02). This was driven by increased fidgeting and irritability and interventions focused on increasing awareness of internal experiences. Conclusions: The findings of the study do not support a larger study on the mobile ACT in BP but have significant implications for future studies seeking mobile therapy for individuals with BP. Trial Registration: ClinicalTrials.gov NCT04098497; https://clinicaltrials.gov/ct2/show/NCT04098497 
%M 37079363
%R 10.2196/43164
%U https://mental.jmir.org/2023/1/e43164
%U https://doi.org/10.2196/43164
%U http://www.ncbi.nlm.nih.gov/pubmed/37079363