<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Ment Health</journal-id><journal-id journal-id-type="publisher-id">mental</journal-id><journal-id journal-id-type="index">16</journal-id><journal-title>JMIR Mental Health</journal-title><abbrev-journal-title>JMIR Ment Health</abbrev-journal-title><issn pub-type="epub">2368-7959</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v12i1e77796</article-id><article-id pub-id-type="doi">10.2196/77796</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Paper</subject></subj-group></article-categories><title-group><article-title>Associations Between Both Smartphone Addiction and Objectively Measured Smartphone Use and Sleep Quality and Duration Among University Students: Cross-Sectional Study</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>Yin</surname><given-names>Jian</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>Tang</surname><given-names>Xuanyi</given-names></name><degrees>BM</degrees><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Liu</surname><given-names>Zeshi</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Gong</surname><given-names>Yangyang</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Yang</surname><given-names>Hui</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Zhang</surname><given-names>Yanping</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib></contrib-group><aff id="aff1"><institution>Department of Laboratory, Second Affiliated Hospital of Xi'an Jiaotong University</institution><addr-line>No. 157 West Five Road</addr-line><addr-line>Xi'an</addr-line><country>China</country></aff><aff id="aff2"><institution>School of Public Health, Shandong University</institution><addr-line>Jinan</addr-line><country>China</country></aff><aff id="aff3"><institution>Department of External Cooperation and Exchange, Shaanxi Provincial Health Commission</institution><addr-line>Xi'an</addr-line><country>China</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Torous</surname><given-names>John</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Massar</surname><given-names>Stijn A A</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Yang</surname><given-names>Tingzhong</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Zhang</surname><given-names>Yutong</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Yanping Zhang, PhD, Department of Laboratory, Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 West Five Road, Xi'an, 710004, China, +86-15929443510; <email>xiziyangzhang@163.com</email></corresp><fn fn-type="equal" id="equal-contrib1"><label>*</label><p>these authors contributed equally</p></fn></author-notes><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>25</day><month>11</month><year>2025</year></pub-date><volume>12</volume><elocation-id>e77796</elocation-id><history><date date-type="received"><day>20</day><month>05</month><year>2025</year></date><date date-type="rev-recd"><day>01</day><month>10</month><year>2025</year></date><date date-type="accepted"><day>02</day><month>10</month><year>2025</year></date></history><copyright-statement>&#x00A9; Jian Yin, Xuanyi Tang, Zeshi Liu, Yangyang Gong, Hui Yang, Yanping Zhang. Originally published in JMIR Mental Health (<ext-link ext-link-type="uri" xlink:href="https://mental.jmir.org">https://mental.jmir.org</ext-link>), 25.11.2025. </copyright-statement><copyright-year>2025</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Mental Health, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://mental.jmir.org/">https://mental.jmir.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://mental.jmir.org/2025/1/e77796"/><abstract><sec><title>Background</title><p>The impact of smartphone use on sleep remains intensely debated. Most existing studies have used self-reported smartphone use data. Moreover, few studies have simultaneously examined associations between both smartphone addiction and objectively measured smartphone use and sleep, and the dose-response relationship between smartphone use and risk of poor sleep has been consistently overlooked, requiring systematic and further research on this topic.</p></sec><sec><title>Objective</title><p>This study aimed to examine the associations between smartphone addiction and objectively measured smartphone use and sleep quality and duration.</p></sec><sec sec-type="methods"><title>Methods</title><p>This cross-sectional study enrolled 17,713 participants from a university in China. We assessed objective smartphone screen time and unlocks by collecting screenshots of use records and measured smartphone addiction using a validated questionnaire. Sleep quality and duration were estimated via the Pittsburgh Sleep Quality Index. Binary logistic regression, linear regression, and restricted cubic spline regression models were used for the analyses.</p></sec><sec sec-type="results"><title>Results</title><p>A total of 14.3% (2533/17,713) of the participants met the criterion for poor sleep, with a mean sleep duration of 507.1 (SD 103.2) minutes per night. Notably, university students with smartphone addiction exhibited 184% higher risk of poor sleep (odds ratio [OR] 2.84, 95% CI 2.59-3.11) and a 15.47-minute&#x2013;shorter nighttime sleep duration (&#x03B2;<italic>=</italic>&#x2013;15.47, 95% CI &#x2212;18.53 to &#x2212;12.42) compared to those without smartphone addiction. Regarding objectively measured smartphone use, participants with &#x2265;63 hours per week of smartphone screen time had 22% higher odds of poor sleep (OR 1.22, 95% CI 1.08-1.37) and a 6.66-minute&#x2013;shorter nighttime sleep duration (&#x03B2;<italic>=</italic>&#x2013;6.66, 95% CI &#x2212;10.19 to &#x2212;3.13) compared to those with 0 to 21 hours of screen time per week, whereas those with approximately 21 to 42 hours per week of smartphone screen time had a 5.47-minute&#x2013;longer nighttime sleep duration (&#x03B2;<italic>=</italic>5.47, 95% CI 1.28-9.65). Similarly, compared to those with 0 to 50 smartphone unlocks per week, participants with &#x2265;400 smartphone unlocks per week showed 61% higher odds of poor sleep (OR 1.61, 95% CI 1.41-1.85) accompanied by a 4.09-minute&#x2013;shorter nighttime sleep duration (&#x03B2;<italic>=</italic>&#x2013;4.09, 95% CI &#x2212;8.08 to &#x2212;0.09), whereas those with approximately 50 to 150 smartphone unlocks per week had a 5.84-minute&#x2013;longer sleep duration (&#x03B2;<italic>=</italic>5.84, 95% CI 2.32-9.36). An inverted U&#x2013;shaped association between smartphone screen time and sleep duration was observed (<italic>P</italic>&#x003C;.001 for nonlinearity).</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>Smartphone addiction, excessive objectively measured smartphone screen time, and unlocks are positively associated with both sleep quality and duration. Restricted cubic spline analyses revealed different nuanced dose-response relationships, with an inverted U&#x2013;shaped association observed between smartphone screen time and sleep duration.</p></sec></abstract><kwd-group><kwd>smartphone addiction</kwd><kwd>smartphone screen time</kwd><kwd>smartphone unlocks</kwd><kwd>sleep disorders</kwd><kwd>sleep duration</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>In the digital age, youths spend more time on smartphones than ever before, and smartphones have become an inescapable part of everyday life [<xref ref-type="bibr" rid="ref1">1</xref>]. Adequate and high-quality sleep plays a pivotal role in sustaining physiological and psychological well-being. Poor sleep quality alongside inadequate duration is both prevalent and strongly linked to elevated risks of adverse health outcomes [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref4">4</xref>] and, thus, has become a notable concern. Over recent decades, epidemiological evidence has indicated a progressive deterioration in both average sleep quality and duration [<xref ref-type="bibr" rid="ref5">5</xref>], with roughly 33% of the global population falling short of internationally recommended nocturnal sleep thresholds (7&#x2010;9 hours per night). Given the public health impact of poor and insufficient sleep, there is a critical need to better understand the potential influence of ubiquitous smartphones in impairing sleep health.</p><p>Numerous studies have linked smartphone use with poor sleep and shorter sleep duration [<xref ref-type="bibr" rid="ref6">6</xref>-<xref ref-type="bibr" rid="ref12">12</xref>], whereas few studies have reported that smartphone screen time correlates with poorer sleep quality but has minimal effects on sleep duration [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref13">13</xref>]. Conversely, 2 studies found no association between the daily use of technology devices and sleep outcomes [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>]. Notably, the current generation of youth, referred to as iGens by Twenge [<xref ref-type="bibr" rid="ref16">16</xref>], has grown up in the smartphone era and is characterized by elevated rates of smartphone use and smartphone addiction [<xref ref-type="bibr" rid="ref17">17</xref>]. University students today belong to the iGeneration, who are more prone to severe smartphone addiction and maladaptive use that may impair sleep quality and duration in the absence of familial oversight. This risk is particularly concerning because poor or insufficient sleep can exacerbate mental health issues, which have already garnered broad societal attention, especially against the backdrop of China&#x2019;s rapidly accelerating pace of life. Previous research has posited that smartphones may affect sleep via multiple mechanisms. First, the time displacement hypothesis posits that excessive smartphone use potentially comes at the cost of sleep [<xref ref-type="bibr" rid="ref18">18</xref>] as each additional hour of screen time theoretically reduces available sleep hours. A prospective cohort study showed that excessive smartphone use was related to shorter total sleep time in children [<xref ref-type="bibr" rid="ref19">19</xref>]; the total sleep time of the smartphone overuse group (smartphone use of over 1 hour per day) was shorter than that of the control group. Second, prolonged smartphone screen time increases exposure to screen-emitted light [<xref ref-type="bibr" rid="ref20">20</xref>]. More light exposure from smartphones could delay melatonin onset, disrupting the circadian rhythm and thereby reducing sleep quality and duration. Phillips et al [<xref ref-type="bibr" rid="ref21">21</xref>] demonstrated that evening exposure to light at intensities below 30 lux, which is comparable to that emitted by smartphones, suppressed melatonin by 50%. Furthermore, the electromagnetic fields emitted by smartphones have also been identified as a significant factor influencing sleep. A study by Huber et al [<xref ref-type="bibr" rid="ref22">22</xref>] revealed that exposure to pulse-modulated electromagnetic fields increased relative regional cerebral blood flow in the dorsolateral prefrontal cortex ipsilateral to the exposure and enhanced electroencephalographic power in the alpha frequency range before sleep onset and in the spindle frequency range during stage 2 sleep. Third, psychological and physical arousal induced by engaging, entertaining, or distressing content from various smartphone apps may also impair the ability to fall asleep and maintain sleep [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]. Meyerson et al [<xref ref-type="bibr" rid="ref25">25</xref>] leveraged estimated bedtimes from 44,000 Reddit users and their 120 million posts, revealing that users who posted 4 or more times within 1 hour before bedtime had a 4-fold higher risk of delayed sleep onset compared to those who posted 2 to 5 hours before bedtime.</p><p>Despite a growing body of research on the association between smartphone use and sleep, methodological and dimensional limitations persist. First, the widespread use of smartphones in everyday life points to the need for rigorous and objective methods that can adequately capture the true links between smartphone use behavior and sleep. However, most existing studies rely on participants&#x2019; self-reported smartphone use data. This is an important limitation because previous research has shown that self-reported smartphone use is prone to recall bias and misclassification errors and does not correlate well with objectively measured smartphone use [<xref ref-type="bibr" rid="ref26">26</xref>-<xref ref-type="bibr" rid="ref29">29</xref>]. A neglected aspect of smartphone use is unlocks, defined as the number of times that users activate their smartphone screen within a specific period, a behavior reflecting compulsive urges for immediate interaction. As a dimension distinct from smartphone screen time, unlocks represent dynamic user-device interaction patterns [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>] whose potential impact on sleep remains understudied. Second, research on the association between smartphone use and sleep has been siloed, focusing exclusively on either smartphone addiction or smartphone use (eg, duration). These 2 dimensions represent different metrics of smartphone use [<xref ref-type="bibr" rid="ref32">32</xref>-<xref ref-type="bibr" rid="ref34">34</xref>]. Smartphone addiction has been defined as an individual&#x2019;s excessive and uncontrollable use of smartphones, resulting in impaired social functioning and psychological and behavioral problems [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]. Smartphone screen time is neither a necessary criterion nor a precise proxy for addiction as users with shorter smartphone screen time may still exhibit addictive symptoms, whereas those with longer screen time might engage in adaptive use [<xref ref-type="bibr" rid="ref32">32</xref>]. Thus, analyzing smartphone addiction and smartphone use behaviors is essential to understanding the full impact of smartphones on sleep. To date, few studies have examined the associations between both smartphone addiction and smartphone use and sleep simultaneously. Moreover, previous research has often treated smartphone addiction and smartphone use behaviors as categorical variables in traditional regression models, thereby overlooking the potential for dose-response associations between continuous smartphone use and risk of poor sleep. Consequently, less is known about associations between different points along the continuum of both smartphone use and smartphone addiction and sleep quality or duration.</p><p>This large-scale study adopted a more holistic perspective with a representative sample, assessing objective smartphone use by collecting screenshots of participants&#x2019; smartphone screen time and unlock records and measuring smartphone addiction through a validated questionnaire, with the aim of examining whether smartphone addiction and objectively measured smartphone use were associated with sleep quality and duration among university students. We also conducted restricted cubic splines (RCS) regression to better understand the dose-response relationship between smartphone use and sleep.</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Study Population</title><p>In this cross-sectional study, a university in Shaanxi province, China, was randomly selected from the provincial registry of higher-education institutions. All 24,156 students in this university were invited to participate in the survey. Before data collection, training sessions were conducted for all class counselors to explain the study objectives and procedures. They subsequently facilitated the anonymous completion of a structured electronic questionnaire by the students. From the 22,047 questionnaires received, submissions were excluded if they met any of the following criteria: (1) completion time of less than 500 seconds, (2) failure on one or more attention-check questions, (3) inability to provide valid smartphone use screenshots, or (4) implausible sleep metric data. Consequently, a total of 17,713 students were included in the final analyses. A flowchart of the screening of the study participants is shown in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p></sec><sec id="s2-2"><title>Ethical Considerations</title><p>The Second Affiliated Hospital of Xi&#x2019;an Jiaotong University provided ethics approval for this study (approval ID: 2022-248). All participants gave their electronic informed consent before taking part in the study. All personally identifiable information was removed during data preparation and analysis and was not included in the manuscript or supplementary materials. No images or visual identifiers of participants are included in the study. Participants received no financial compensation for their involvement. This study followed the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) reporting guideline and CONSORT-EHEALTH (Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online Telehealth) checklist [<xref ref-type="bibr" rid="ref37">37</xref>]. The CONSORT-EHEALTH checklist is shown in <xref ref-type="supplementary-material" rid="app4">Checklist 1</xref>.</p></sec><sec id="s2-3"><title>Measures</title><sec id="s2-3-1"><title>Smartphone Addiction</title><p>The Mobile Phone Addiction Tendency Scale (MPATS), originally developed by Xiong et al [<xref ref-type="bibr" rid="ref38">38</xref>] for Chinese university populations, was used to evaluate smartphone addiction in this study. The scale comprises 16 items across 4 dimensions consisting of salience, withdrawal symptoms, social comfort, and mood changes. The items are scored on a scale from 1 (&#x201C;very inconsistent&#x201D;) to 5 (&#x201C;very consistent&#x201D;), yielding a total score between 16 and 80. Elevated total scores correlate with greater severity of smartphone addiction, with scores of &#x2265;48 defining smartphone addiction. In this study, the Cronbach &#x03B1; coefficient was 0.94.</p></sec><sec id="s2-3-2"><title>Objectively Measured Smartphone Use</title><p>The objectively measured smartphone use included smartphone screen time and unlocks. In this study, upon providing informed consent, participants were instructed to capture and submit screenshots of their smartphone use during the previous full week, which was automatically recorded by the built-in Screen Time tool of the iOS system and the Digital Wellbeing tool of the Android system. The operating system passively records these behavioral data through a triggering mechanism involving screen photoelectric sensors, representing an objective measurement approach independent of self-reporting. Previous studies have validated the use of such built-in tracking systems to obtain objective smartphone use behavior as accurate and reliable for capturing actual use patterns [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref39">39</xref>]. The 7-day assessment period aligns with those of most studies in this field [<xref ref-type="bibr" rid="ref40">40</xref>-<xref ref-type="bibr" rid="ref42">42</xref>]. There is evidence suggesting that less than 1 week of smartphone data collection is already sufficient to capture typical smartphone use behaviors [<xref ref-type="bibr" rid="ref43">43</xref>]. Furthermore, to mitigate potential variation between weekdays and weekends and enhance the representativeness, participants were instructed to submit screenshots encompassing a full week (5 weekdays and 2 weekend days). Two weeks before the formal investigation of this study, we instructed the participants to activate the function for smartphone records to ensure the availability of objective data. We then provided step-by-step instructions for screenshots for different brands and types of smartphones and required them to submit the screenshots covering (1) smartphone screen time during the previous week and (2) number of smartphone unlocks during the previous week. According to the distribution of the screen time data, we classified participants into 4 groups (approximately 0-21, 21-42, 42-63, and &#x2265;63 hours per week). In accordance with the distribution of our datasets, and to ensure better practical guidance, we partitioned smartphone unlocks into quartiles, selecting integer thresholds around quartile points. Consequently, we classified participants into 4 groups for smartphone unlocks (approximately 0-50, 50-150, 150-400, and &#x2265;400 times per week).</p></sec><sec id="s2-3-3"><title>Sleep Quality and Duration</title><p>The Pittsburgh Sleep Quality Index (PSQI) was administered to evaluate sleep quality over the previous month [<xref ref-type="bibr" rid="ref44">44</xref>]. Comprising 19 items, the instrument is structured into 7 domains (subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medication, and daytime dysfunction). Each domain is scored on a scale between 0 and 3, with elevated scores representing poorer sleep. Aggregating scores across domains produces a composite PSQI score spanning 0 to 21, where higher scores signify poorer sleep quality. A score of &#x2265;8 was used to define poor sleep in accordance with the validated cutoff for the Chinese population [<xref ref-type="bibr" rid="ref45">45</xref>], which has demonstrated good reliability and validity in previous representative studies [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>]. In this study, the Cronbach &#x03B1; coefficient of the PSQI was 0.85.</p><p>Sleep duration was evaluated via the following question: &#x201C;Over the past month, how many hours did you typically spend asleep at night? This time should exclude time spent in bed without falling asleep.&#x201D;</p></sec><sec id="s2-3-4"><title>Covariates</title><p>We developed a structured questionnaire to gather several confounding factors. Sociodemographic information included gender, university year, race, registered permanent residence, whether the participants had siblings, and parental educational attainment. As described in a previous study [<xref ref-type="bibr" rid="ref48">48</xref>], health-related lifestyles comprised current smoking, current drinking, physical activity, and rational diet. Participants who had smoked at least one cigarette in the previous 30 days were classified as current smokers. Similarly, those who had consumed at least one glass of wine during the previous 30 days were categorized as currently drinking. The International Physical Activity Questionnaire&#x2013;Short Form was used to assess physical activity [<xref ref-type="bibr" rid="ref49">49</xref>], categorizing activity levels into low, moderate, and high according to established calculated metabolic equivalents. An irrational diet was defined as participants consuming red meat every day or vegetables and fruits less than daily.</p><p>As previous studies have reported significant relationships between social support and sleep, the Adolescent Social Support Scale (ASSS) was administered to quantify social support [<xref ref-type="bibr" rid="ref50">50</xref>]. The ASSS is a 16-item instrument, with each item scored on a scale from 1 to 5. A higher score signifies greater social support. The Cronbach &#x03B1; coefficient of the ASSS was 0.88, indicating strong internal consistency.</p></sec></sec><sec id="s2-4"><title>Statistical Analyses</title><p>Participant characteristics were described using frequency distributions for categorical variables, as well as means and SDs for continuous variables. Three sets of binary logistic and linear regression models were constructed to estimate odds ratios and 95% CIs for poor sleep, as well as &#x03B2; coefficients and corresponding 95% CIs for sleep duration. Covariates included sex, university year, race, registered permanent residence, whether the participants had siblings, parental educational attainment, current smoking, current drinking, physical activity, rational diet, and social support. RCS regression was used to model dose-response associations between both smartphone addiction and objectively measured smartphone use and sleep quality and duration. In addition, we tested for interaction between smartphone use and sex to determine whether sex modified the relationships. To reduce the possible effects of the unbalanced sex ratio of the participants, we conducted a sex-weighted logistic regression. Moreover, a multilevel model with college under university as a random effect was conducted to mitigate the college under university clustering effects.</p><p>In all tests, a 2-sided <italic>P</italic> value of &#x003C;.05 was used as a significance threshold. The R software (version 4.0.2; R Foundation for Statistical Computing) was used for all data analyses.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Participant Characteristics</title><p><xref ref-type="table" rid="table1">Table 1</xref> presents the characteristics of the participants in this study. Of the 17,713 participants, 6087 (34.4%) were male, and 11,626 (65.6%) were female. A total of 95.9% (16,992/17,713) were of Han ethnicity, 43.1% (7633/17,713) lived in rural areas, and 34.4% (6098/17,713) were from single-child families. Notably, 14.3% (2533/17,713) of the participants met the criteria for poor sleep (PSQI&#x2265;8), with a mean sleep duration of 507.1 (SD 103.2) minutes per night. Overall, 24.9% (4418/17,713) of the participants met the criteria for smartphone addiction (MPATS score &#x2265;48), with a mean MPATS score of 37.4 (SD 13.3). Mean smartphone screen time was 49.1 (SD 29.9) hours per week, and mean unlocks were 391.1 (SD 278.3) times per week.</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Characteristics of the participants (N=17,713).</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Characteristic</td><td align="left" valign="bottom">Total participants (N=17,713)</td><td align="left" valign="bottom">Participants who did not meet the criteria for poor sleep (n=15,180)</td><td align="left" valign="bottom">Participants who met the criteria for poor sleep (n=2533)</td><td align="left" valign="bottom"><italic>P</italic> value</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="4">Sex, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Male</td><td align="left" valign="top">6087 (34.4)</td><td align="left" valign="top">5315 (87.3)</td><td align="left" valign="top">772 (12.7)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Female</td><td align="left" valign="top">11,626 (65.6)</td><td align="left" valign="top">9865 (84.9)</td><td align="left" valign="top">1761 (15.1)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">University year, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>First</td><td align="left" valign="top">6111 (34.5)</td><td align="left" valign="top">5256 (86.0)</td><td align="left" valign="top">855 (14.0)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Second</td><td align="left" valign="top">4515 (25.5)</td><td align="left" valign="top">3803 (84.2)</td><td align="left" valign="top">712 (15.8)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Third</td><td align="left" valign="top">4647 (26.2)</td><td align="left" valign="top">3959 (85.2)</td><td align="left" valign="top">688 (14.8)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Fourth or above</td><td align="left" valign="top">2440 (13.8)</td><td align="left" valign="top">2162 (88.6)</td><td align="left" valign="top">278 (11.4)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Ethnicity, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Han</td><td align="left" valign="top">16,992 (95.9)</td><td align="left" valign="top">14,599 (85.9)</td><td align="left" valign="top">2393 (14.1)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Others</td><td align="left" valign="top">721 (4.1)</td><td align="left" valign="top">581 (80.6)</td><td align="left" valign="top">140 (19.4)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Registered permanent residence, n (%)</td><td align="left" valign="top">.01</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Rural</td><td align="left" valign="top">7633 (43.1)</td><td align="left" valign="top">6601 (86.5)</td><td align="left" valign="top">1032 (13.5)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Urban</td><td align="left" valign="top">10,080 (56.9)</td><td align="left" valign="top">8579 (85.1)</td><td align="left" valign="top">1501 (14.9)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Siblings, n (%)</td><td align="left" valign="top">.73</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>No</td><td align="left" valign="top">6098 (34.4)</td><td align="left" valign="top">5234 (85.8)</td><td align="left" valign="top">864 (14.2)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Yes</td><td align="left" valign="top">11,615 (65.6)</td><td align="left" valign="top">9946 (85.6)</td><td align="left" valign="top">1669 (14.4)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Maternal educational attainment, n (%)</td><td align="left" valign="top">.20</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Middle school or lower</td><td align="left" valign="top">9915 (56.0)</td><td align="left" valign="top">8494 (85.7)</td><td align="left" valign="top">1421 (14.3)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>High school</td><td align="left" valign="top">4134 (23.3)</td><td align="left" valign="top">3572 (86.4)</td><td align="left" valign="top">562 (13.6)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>University or higher</td><td align="left" valign="top">3664 (20.7)</td><td align="left" valign="top">3114 (85.0)</td><td align="left" valign="top">550 (15.0)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Paternal educational attainment, n (%)</td><td align="left" valign="top">.07</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Middle school or lower</td><td align="left" valign="top">8600 (48.6)</td><td align="left" valign="top">7345 (85.4)</td><td align="left" valign="top">1255 (14.6)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>High school</td><td align="left" valign="top">4410 (24.9)</td><td align="left" valign="top">3826 (86.8)</td><td align="left" valign="top">584 (13.2)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>University or higher</td><td align="left" valign="top">4703 (26.6)</td><td align="left" valign="top">4009 (85.2)</td><td align="left" valign="top">694 (14.8)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Current smoking, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>No</td><td align="left" valign="top">14,599 (82.4)</td><td align="left" valign="top">12,747 (87.3)</td><td align="left" valign="top">1852 (12.7)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Yes</td><td align="left" valign="top">3114 (17.6)</td><td align="left" valign="top">2433 (78.1)</td><td align="left" valign="top">681 (21.9)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Current drinking, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>No</td><td align="left" valign="top">13,369 (75.5)</td><td align="left" valign="top">11,826 (88.5)</td><td align="left" valign="top">1543 (11.5)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Yes</td><td align="left" valign="top">4344 (24.5)</td><td align="left" valign="top">3354 (77.2)</td><td align="left" valign="top">990 (22.8)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Rational diet, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Yes</td><td align="left" valign="top">2378 (13.4)</td><td align="left" valign="top">2162 (90.9)</td><td align="left" valign="top">216 (9.1)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>No</td><td align="left" valign="top">15,335 (86.6)</td><td align="left" valign="top">13,018 (84.9)</td><td align="left" valign="top">2317 (15.1)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="4">Physical exercise, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Moderate or high</td><td align="left" valign="top">3672 (20.7)</td><td align="left" valign="top">3247 (88.4)</td><td align="left" valign="top">425 (11.6)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Low</td><td align="left" valign="top">14,041 (79.3)</td><td align="left" valign="top">11,933 (85.0)</td><td align="left" valign="top">2108 (15.0)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">Social support score, mean (SD, 16~80)</td><td align="left" valign="top">68.0 (15.2)</td><td align="left" valign="top">69.2 (14.9)</td><td align="left" valign="top">61.0 (14.7)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top" colspan="4">Smartphone addiction, n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>No</td><td align="left" valign="top">13,295 (75.1)</td><td align="left" valign="top">11,998 (90.2)</td><td align="left" valign="top">1297 (9.8)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Yes</td><td align="left" valign="top">4418 (24.9)</td><td align="left" valign="top">3182 (72.0)</td><td align="left" valign="top">1236 (28.0)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">MPATS<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup> score, mean (SD, 16~80)</td><td align="left" valign="top">37.4 (13.3)</td><td align="left" valign="top">36.0 (12.7)</td><td align="left" valign="top">46.0 (13.3)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;salience, mean (SD)</td><td align="left" valign="top">8.1 (3.3)</td><td align="left" valign="top">7.8 (3.2)</td><td align="left" valign="top">10.0 (3.6)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;withdrawal symptoms, mean (SD)</td><td align="left" valign="top">15.3 (5.5)</td><td align="left" valign="top">15.4 (5.2)</td><td align="left" valign="top">18.7 (5.3)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;social comfort, mean (SD)</td><td align="left" valign="top">7.2 (3.1)</td><td align="left" valign="top">6.9 (2.9)</td><td align="left" valign="top">8.8 (3.3)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;mood changes, mean (SD)</td><td align="left" valign="top">6.8 (2.9)</td><td align="left" valign="top">6.5 (2.7)</td><td align="left" valign="top">8.5 (3.0)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top" colspan="4">Smartphone screen time (h per wk), n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>0-21</td><td align="left" valign="top">4117 (23.2)</td><td align="left" valign="top">3546 (86.1)</td><td align="left" valign="top">571 (13.9)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>21-42</td><td align="left" valign="top">2896 (16.3)</td><td align="left" valign="top">2570 (88.7)</td><td align="left" valign="top">326 (11.3)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>42-63</td><td align="left" valign="top">4588 (25.9)</td><td align="left" valign="top">3973 (86.6)</td><td align="left" valign="top">615 (13.4)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>&#x2265;63</td><td align="left" valign="top">6112 (34.5)</td><td align="left" valign="top">5091 (83.3)</td><td align="left" valign="top">1021 (16.7)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">Smartphone screen time (h per wk), mean (SD)</td><td align="left" valign="top">49.1 (29.9)</td><td align="left" valign="top">48.6 (29.6)</td><td align="left" valign="top">52.4 (31.0)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top" colspan="4">Smartphone unlocks (times per wk), n (%)</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>0-50</td><td align="left" valign="top">4062 (22.9)</td><td align="left" valign="top">3590 (88.4)</td><td align="left" valign="top">472 (11.6)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>50-150</td><td align="left" valign="top">5972 (33.7)</td><td align="left" valign="top">5195 (87.0)</td><td align="left" valign="top">777 (13.0)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>150-400</td><td align="left" valign="top">4249 (24.0)</td><td align="left" valign="top">3598 (84.7)</td><td align="left" valign="top">651 (15.3)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>&#x2265;400</td><td align="left" valign="top">3430 (19.4)</td><td align="left" valign="top">2797 (81.5)</td><td align="left" valign="top">633 (18.5)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">Smartphone unlocks (times per wk), mean (SD)</td><td align="left" valign="top">391.1 (278.3)</td><td align="left" valign="top">384.4 (274.2)</td><td align="left" valign="top">425.5 (296.4)</td><td align="left" valign="top">&#x003C;.001</td></tr></tbody></table><table-wrap-foot><fn id="table1fn1"><p><sup>a</sup>MPATS: Mobile Phone Addiction Tendency Scale.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-2"><title>Association Between Smartphone Use and Sleep Quality</title><p>The associations of smartphone addiction, screen time, and unlocks with sleep quality were presented in (<xref ref-type="table" rid="table2">Table 2</xref>). After adjusting for sex, university year, race, registered permanent residence, whether the participants had siblings, parental educational attainment, current smoking, current drinking, physical activity, rational diet, and social support, smartphone addiction was associated with poor sleep (OR 2.84, 95% CI 2.59-3.11). A 5-point increase in the MPATS score was substantially associated with poor sleep (OR 1.27, 95% CI 1.25-1.30). Objectively measured smartphone use was also linked to sleep quality. Compared with participants reporting 0&#x2013;21 hours/week of smartphone screen time, those with &#x2265;63 hours/week had higher odds of poor sleep (OR 1.22, 95% CI 1.08-1.37). While those with 21&#x2013;42 hour/week (OR 0.86, 95% CI 0.74-1.00) and 42-63 hour/week (OR 0.98, 95% CI 0.86-1.12) exhibited no significant increase in sleep quality. Compared with participants reporting 0-50 times/week of unlocks, those with 150~400 times/week (OR 1.34, 95% CI 1.18-1.53) and &#x2265;400 times/week had higher poor sleep odds (OR 1.61, 95% CI 1.41-1.85), while those with 50-150 times/week (OR 1.11, 95% CI 0.97-1.26) exhibited no change in sleep duration. A 21-hour/week increase in smartphone screen time (OR 1.08, 95% CI 1.04-1.11) and a 50 times/week increase in unlocks (OR 1.03, 95% CI 1.02-1.04<italic>)</italic> were associated with poor sleep. In models 1 and 2, the ORs increased slightly. Additionally, RCS analyses suggested nonlinear associations of MPATS score (<italic>P=</italic>.01 for nonlinearity), smartphone screen time (<italic>P</italic>&#x003C;.001 for nonlinearity), and unlocks (<italic>P</italic>=.02 for nonlinearity) with the increasing risk of poor sleep (<xref ref-type="fig" rid="figure1">Figure 1</xref>).</p><table-wrap id="t2" position="float"><label>Table 2.</label><caption><p>Associations between smartphone addiction, smartphone screen time, and smartphone unlocks and sleep quality and duration.</p></caption><table id="table2" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Smartphone use variable</td><td align="left" valign="bottom" colspan="3">Poor sleep<italic>,</italic> OR<sup><xref ref-type="table-fn" rid="table2fn1">a</xref></sup> (95% CI)</td><td align="left" valign="bottom" colspan="3">Sleep duration, &#x03B2; (95% CI)</td></tr><tr><td align="left" valign="bottom"/><td align="left" valign="bottom">Model 1<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup></td><td align="left" valign="bottom">Model 2<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup></td><td align="left" valign="bottom">Model 3<sup><xref ref-type="table-fn" rid="table2fn4">d</xref></sup></td><td align="left" valign="bottom">Model 1</td><td align="left" valign="bottom">Model 2</td><td align="left" valign="bottom">Model 3</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="7">Smartphone addiction</td></tr><tr><td align="left" valign="top">&#x2003;No</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td></tr><tr><td align="left" valign="top">&#x2003;Yes</td><td align="left" valign="top">3.54 (3.25 to 3.87)</td><td align="left" valign="top">3.20 (2.93 to 3.50)</td><td align="left" valign="top">2.84 (2.59 to 3.11)</td><td align="left" valign="top">&#x2212;19.19 (&#x2212;22.19 to &#x2013;16.20)</td><td align="left" valign="top">&#x2212;17.99 (&#x2212;21.01 to &#x2013;14.96)</td><td align="left" valign="top">&#x2212;15.47 (&#x2212;18.53 to &#x2013;12.42)</td></tr><tr><td align="left" valign="top">MPATS<sup><xref ref-type="table-fn" rid="table2fn5">e</xref></sup> score&#x2014;sleep per-5 score</td><td align="left" valign="top">1.33 (1.31 to 1.36)</td><td align="left" valign="top">1.31 (1.28 to 1.33)</td><td align="left" valign="top">1.27 (1.25 to 1.30)</td><td align="left" valign="top">&#x2212;3.93 (&#x2212;4.42 to &#x2013;3.44)</td><td align="left" valign="top">&#x2212;3.72 (&#x2212;4.22 to &#x2013;3.22)</td><td align="left" valign="top">&#x2212;3.20 (&#x2212;3.71 to &#x2013;2.69)</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;salience</td><td align="left" valign="top">1.21 (1.19 to 1.22)</td><td align="left" valign="top">1.19 (1.17 to 1.21)</td><td align="left" valign="top">1.17 (1.15 to 1.18)</td><td align="left" valign="top">&#x2212;2.58 (&#x2212;2.98 to &#x2013;2.19)</td><td align="left" valign="top">&#x2212;2.41 (&#x2212;2.80 to &#x2013;2.01)</td><td align="left" valign="top">&#x2212;1.98 (&#x2212;2.39 to &#x2013;1.57)</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;withdrawal symptoms</td><td align="left" valign="top">1.14 (1.13 to 1.15)</td><td align="left" valign="top">1.13 (1.12 to 1.14)</td><td align="left" valign="top">1.12 (1.11 to 1.13)</td><td align="left" valign="top">&#x2212;1.73 (&#x2212;1.97 to &#x2013;1.49)</td><td align="left" valign="top">&#x2212;1.62 (&#x2212;1.87 to &#x2013;1.38)</td><td align="left" valign="top">&#x2212;1.39 (&#x2212;1.64 to &#x2013;1.15)</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;social comfort</td><td align="left" valign="top">1.21 (1.19 to 1.23)</td><td align="left" valign="top">1.20 (1.18 to 1.22)</td><td align="left" valign="top">1.17 (1.16 to 1.19)</td><td align="left" valign="top">&#x2212;3.25 (&#x2212;3.68 to &#x2013;2.83)</td><td align="left" valign="top">&#x2212;3.09 (&#x2212;3.53 to &#x2013;2.67)</td><td align="left" valign="top">&#x2212;2.65 (&#x2212;3.09 to &#x2013;2.20)</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;mood changes</td><td align="left" valign="top">1.27 (1.26 to 1.29)</td><td align="left" valign="top">1.25 (1.23 to 1.27)</td><td align="left" valign="top">1.23 (1.21 to 1.24)</td><td align="left" valign="top">&#x2212;3.37 (&#x2212;3.82 to &#x2013;2.91)</td><td align="left" valign="top">&#x2212;3.17 (&#x2212;3.63 to &#x2013;2.71)</td><td align="left" valign="top">&#x2212;2.74 (&#x2212;3.21 to &#x2013;2.27)</td></tr><tr><td align="left" valign="top" colspan="7">Smartphone screen time (h per wk)</td></tr><tr><td align="left" valign="top">&#x2003;0-21</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td></tr><tr><td align="left" valign="top">&#x2003;21-42</td><td align="left" valign="top">0.79 (0.69 to 0.92)</td><td align="left" valign="top">0.84 (0.72 to 0.96)</td><td align="left" valign="top">0.86 (0.74 to 1.00)</td><td align="left" valign="top">6.19 (1.99 to 10.39)</td><td align="left" valign="top">5.71 (1.52 to 9.91)</td><td align="left" valign="top">5.47 (1.28 to 9.65)</td></tr><tr><td align="left" valign="top">&#x2003;42-63</td><td align="left" valign="top">0.97 (0.85 to 1.09)</td><td align="left" valign="top">0.97 (0.85 to 1.09)</td><td align="left" valign="top">0.98 (0.86 to 1.12)</td><td align="left" valign="top">3.48 (&#x2212;0.25 to 7.21)</td><td align="left" valign="top">3.37 (&#x2212;0.36 to 7.11)</td><td align="left" valign="top">3.42 (&#x2212;0.30 to 7.14)</td></tr><tr><td align="left" valign="top">&#x2003;&#x2265;63</td><td align="left" valign="top">1.22 (1.09 to 1.37)</td><td align="left" valign="top">1.19 (1.06 to 1.34)</td><td align="left" valign="top">1.22 (1.08 to 1.37)</td><td align="left" valign="top">&#x2212;7.07 (&#x2212;10.60 to &#x2013;3.53)</td><td align="left" valign="top">&#x2212;6.86 (&#x2212;10.40 to &#x2013;3.32)</td><td align="left" valign="top">&#x2212;6.66 (&#x2212;10.19 to &#x2013;3.13)</td></tr><tr><td align="left" valign="top"><italic>P</italic> value for the trend</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top">Smartphone screen time increase of 21 h per week</td><td align="left" valign="top">1.09 (1.05 to 1.12)</td><td align="left" valign="top">1.08 (1.04 to 1.11)</td><td align="left" valign="top">1.08 (1.04 to 1.11)</td><td align="left" valign="top">&#x2212;2.21 (&#x2212;3.14 to &#x2013;1.28)</td><td align="left" valign="top">&#x2212;2.12 (&#x2212;3.05 to &#x2013;1.19)</td><td align="left" valign="top">&#x2212;1.99 (&#x2212;2.93 to &#x2013;1.07)</td></tr><tr><td align="left" valign="top" colspan="7">Smartphone unlocks (times per wk)</td></tr><tr><td align="left" valign="top">&#x2003;0-50</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td></tr><tr><td align="left" valign="top">&#x2003;50-150</td><td align="left" valign="top">1.14 (1.01 to 1.29)</td><td align="left" valign="top">1.08 (0.95 to 1.22)</td><td align="left" valign="top">1.11 (0.97 to 1.26)</td><td align="left" valign="top">5.69 (2.16 to 9.22)</td><td align="left" valign="top">5.86 (2.33 to 9.39)</td><td align="left" valign="top">5.84 (2.32 to 9.36)</td></tr><tr><td align="left" valign="top">&#x2003;150-400</td><td align="left" valign="top">1.38 (1.22 to 1.57)</td><td align="left" valign="top">1.31 (1.15 to 1.50)</td><td align="left" valign="top">1.34 (1.18 to 1.53)</td><td align="left" valign="top">&#x2212;3.75 (&#x2212;7.56 to 0.06)</td><td align="left" valign="top">&#x2212;3.44 (&#x2212;7.25 to 0.37)</td><td align="left" valign="top">&#x2212;3.28 (&#x2212;7.08 to 0.52)</td></tr><tr><td align="left" valign="top">&#x2003;&#x2265;400</td><td align="left" valign="top">1.74 (1.53 to 1.98)</td><td align="left" valign="top">1.54 (1.35 to 1.76)</td><td align="left" valign="top">1.61 (1.41 to 1.85)</td><td align="left" valign="top">&#x2212;4.79 (&#x2212;8.77 to &#x2013;0.79)</td><td align="left" valign="top">&#x2212;4.05 (&#x2212;8.06 to &#x2013;0.04)</td><td align="left" valign="top">&#x2212;4.09 (&#x2212;8.08 to &#x2013;0.09)</td></tr><tr><td align="left" valign="top"><italic>P</italic> value for the trend</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td></tr><tr><td align="left" valign="top">Smartphone unlocks per 50 times per wk</td><td align="left" valign="top">1.04 (1.03 to 1.04)</td><td align="left" valign="top">1.03 (1.02 to 1.04)</td><td align="left" valign="top">1.03 (1.02 to 1.04)</td><td align="left" valign="top">&#x2212;0.53 (&#x2212;0.78 to &#x2013;0.28)</td><td align="left" valign="top">&#x2212;0.49 (&#x2212;0.74 to &#x2013;0.23)</td><td align="left" valign="top">&#x2212;0.49 (&#x2212;0.74 to &#x2013;0.23)</td></tr></tbody></table><table-wrap-foot><fn id="table2fn1"><p><sup>a</sup>OR: odds ratio.</p></fn><fn id="table2fn2"><p><sup>b</sup>Adjusted for sex, university year, race, registered permanent residence, whether the participants had siblings, and parental educational attainment.</p></fn><fn id="table2fn3"><p><sup>c</sup>Adjusted for sex, university year, race, registered permanent residence, whether the participants had siblings, parental educational attainment, current smoking, current drinking, physical activity, and rational diet.</p></fn><fn id="table2fn4"><p><sup>d</sup>Adjusted for sex, university year, race, registered permanent residence, whether the participants had siblings, parental educational attainment, current smoking, current drinking, physical activity, rational diet, and social support.</p></fn><fn id="table2fn5"><p><sup>e</sup>MPATS: Mobile Phone Addiction Tendency Scale.</p></fn></table-wrap-foot></table-wrap><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>Restricted cubic spline regression analyses of the association between smartphone addiction, smartphone screen time, and smartphone unlocks and risk of poor sleep quality and reduction in sleep duration. These analyses were adjusted for sex, university year, race, registered permanent residence, whether the participants had siblings, parental educational attainment, current smoking, current drinking, physical activity, rational diet, and social support. MPATS: Mobile Phone Addiction Tendency Scale; OR: odds ratio.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mental_v12i1e77796_fig01.png"/></fig><sec id="s3-2-1"><title>Association Between Smartphone Use and Sleep Duration</title><p>In model 3 in <xref ref-type="table" rid="table2">Table 2</xref>, smartphone addiction remained substantially associated with shorter sleep duration (&#x03B2;<italic>=</italic>&#x2013;15.47, 95% CI &#x2212;18.53 to &#x2212;12.42). For objectively measured smartphone use, compared with participants reporting 0 to 21 hours per week of smartphone screen time, those with &#x2265;63 hours per week had a shorter sleep duration (&#x03B2;<italic>=</italic>&#x2013;6.66, 95% CI &#x2212;10.19 to &#x2212;3.13), whereas 21 to 42 hours of screen time per week (&#x03B2;=5.47, 95% CI 1.28-9.65) were linked to longer sleep duration, and those with 42 to 63 hours of screen time per week (&#x03B2;=3.42, 95% CI &#x2212;0.30 to 7.14) showed no significant association with sleep duration. Similarly, compared to those with approximately 0 to 50 smartphone unlocks per week, those with &#x2265;400 unlocks per week had a significantly shorter sleep duration (&#x03B2;<italic>=</italic>&#x2013;4.09, 95% CI &#x2212;8.08 to &#x2212;0.0), and participants with 50 to 150 smartphone unlocks per week had a longer sleep duration (&#x03B2;<italic>=</italic>5.84, 95% CI 2.32-9.36). No substantial increase in sleep duration (&#x03B2;<italic>=</italic>&#x2013;3.28, 95% CI &#x2212;7.07 to 0.52) was observed for those with approximately 150 to 400 unlocks per week. Notably, each 5-point increase in the MPATS score (&#x03B2;<italic>=</italic>&#x2013;3.20, 95% CI &#x2212;3.71 to &#x2212;2.69), 21&#x2013;hour per week increase in smartphone screen time (&#x03B2;<italic>=</italic>&#x2013;1.99, 95% CI &#x2212;2.93 to &#x2212;1.07), and 50&#x2013;time per week increase in unlocks (&#x03B2;<italic>=</italic>&#x2013;0.49, 95% CI &#x2212;0.74 to &#x2212;0.23) was substantially negatively associated with sleep duration. In models 1 and 2, the &#x03B2; coefficients were not changed materially. The results from the sex-weighted logistic regression model (<xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>) and multilevel model with college as a random effect (<xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref>) were consistent with the primary findings, showing no significant changes. The RCS analyses suggested positive nonlinear associations between increasing MPATS score and shortened sleep duration (<italic>P</italic>&#x003C;.001 for nonlinearity). What is more, an inverted U&#x2013;shape nonlinear relationship was observed between smartphone screen time and reduction in sleep duration (<italic>P</italic>&#x003C;.001 for nonlinearity), whereas increasing smartphone unlocks were found to be associated with monotonically decreasing sleep duration (<italic>P</italic>=.31 for nonlinearity; <xref ref-type="fig" rid="figure1">Figure 1</xref>).</p></sec></sec><sec id="s3-3"><title>Sex-Stratified Analyses</title><p>The results of the sex-stratified analyses are shown in <xref ref-type="table" rid="table3">Table 3</xref>. This study found significant sex-specific differences in the relationships between smartphone screen time (<italic>P=</italic>.01 for the interaction) and unlocks (<italic>P=</italic>.002 for the interaction) and sleep duration. Notably, a 21&#x2013;hour per week increase in smartphone screen time (&#x03B2;<italic>=</italic>&#x2013;0.13, 95% CI 0.19 to &#x2212;0.08) and a 50&#x2013;time per week increase in unlocks (&#x03B2;<italic>=</italic>&#x2013;0.77, 95% CI &#x2212;1.08 to &#x2212;0.47) were significantly associated with sleep duration in female individuals but not significant in male individuals. No significant sex-specific differences were observed in the relationships between smartphone addiction and sleep quality and duration (<italic>P</italic>&#x003E;.05 for the interaction in all cases), nor were there significant associations between smartphone screen time and unlocks and sleep quality (<italic>P</italic>&#x003E;.05 for the interaction in all cases; <xref ref-type="table" rid="table3">Table 3</xref>).</p><table-wrap id="t3" position="float"><label>Table 3.</label><caption><p>Sex-specific associations between smartphone addiction, smartphone screen time, and smartphone unlocks and sleep quality and duration</p></caption><table id="table3" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Smartphone use variable<sup><xref ref-type="table-fn" rid="table3fn1">a</xref></sup></td><td align="left" valign="bottom" colspan="2">Poor sleep<italic>,</italic> OR<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup> (95% CI)</td><td align="left" valign="bottom"><italic>P</italic> value for the interaction of smartphone use and sex on sleep</td><td align="left" valign="bottom" colspan="2">Sleep duration, &#x03B2; (95% CI)</td><td align="left" valign="bottom"><italic>P</italic> value for the interaction</td></tr><tr><td align="left" valign="bottom"/><td align="left" valign="bottom">Male individuals</td><td align="left" valign="bottom">Female individuals</td><td align="left" valign="bottom"/><td align="left" valign="bottom">Male individuals</td><td align="left" valign="bottom">Female individuals</td><td align="left" valign="bottom"/></tr></thead><tbody><tr><td align="left" valign="top">Smartphone addiction</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top">.70</td><td align="left" valign="top" colspan="2"/><td align="left" valign="top">.60</td></tr><tr><td align="left" valign="top">&#x2003;No</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top"/><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;Yes</td><td align="left" valign="top">2.74 (2.32 to 3.22)</td><td align="left" valign="top">2.89 (2.59 to 3.23)</td><td align="left" valign="top"/><td align="left" valign="top">&#x2212;16.18 (&#x2212;21.80 to &#x2212;10.55)</td><td align="left" valign="top">&#x2212;14.74 (&#x2212;18.36 to &#x2212;11.13)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">MPATS<sup><xref ref-type="table-fn" rid="table3fn3">c</xref></sup> score per-5</td><td align="left" valign="top">1.27 (1.23 to 1.31)</td><td align="left" valign="top">1.28 (1.25 to 1.31)</td><td align="left" valign="top">.70</td><td align="left" valign="top">&#x2212;3.07 (&#x2212;3.96 to &#x2212;2.17)</td><td align="left" valign="top">&#x2212;3.19 (&#x2212;3.82 to &#x2212;2.57)</td><td align="left" valign="top">.74</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;salience</td><td align="left" valign="top">1.12 (1.10 to 1.14)</td><td align="left" valign="top">1.12 (1.11 to 1.13)</td><td align="left" valign="top">.96</td><td align="left" valign="top">&#x2212;1.38 (&#x2212;1.82 to &#x2212;0.95)</td><td align="left" valign="top">&#x2212;1.36 (&#x2212;1.66 to &#x2212;1.07)</td><td align="left" valign="top">.86</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;withdrawal symptoms</td><td align="left" valign="top">1.18 (1.15 to 1.20)</td><td align="left" valign="top">1.16 (1.14 to 1.18)</td><td align="left" valign="top">.46</td><td align="left" valign="top">&#x2212;2.13 (&#x2212;2.83 to &#x2212;1.43)</td><td align="left" valign="top">&#x2212;1.81 (&#x2212;2.31 to &#x2212;1.31)</td><td align="left" valign="top">.51</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;social comfort</td><td align="left" valign="top">1.19 (1.16 to 1.22)</td><td align="left" valign="top">1.17 (1.15 to 1.19)</td><td align="left" valign="top">.33</td><td align="left" valign="top">&#x2212;2.58 (&#x2212;3.39 to &#x2212;1.77)</td><td align="left" valign="top">&#x2212;2.67 (&#x2212;3.18 to &#x2212;2.15)</td><td align="left" valign="top">.94</td></tr><tr><td align="left" valign="top">MPATS score&#x2014;mood changes</td><td align="left" valign="top">1.22 (1.19 to 1.26)</td><td align="left" valign="top">1.23 (1.20 to 1.25)</td><td align="left" valign="top">.87</td><td align="left" valign="top">&#x2212;2.62 (&#x2212;3.47 to &#x2212;1.76)</td><td align="left" valign="top">&#x2212;2.70 (&#x2212;3.27 to &#x2212;2.14)</td><td align="left" valign="top">.81</td></tr><tr><td align="left" valign="top" colspan="3">Smartphone screen time (h per wk)</td><td align="left" valign="top">.57</td><td align="left" valign="top" colspan="2"/><td align="left" valign="top">.22</td></tr><tr><td align="left" valign="top">&#x2003;0-21</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top"/><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;21-42</td><td align="left" valign="top">0.87 (0.68 to 1.19)</td><td align="left" valign="top">0.87 (0.72 to 1.05)</td><td align="left" valign="top"/><td align="left" valign="top">7.00 (&#x2212;0.13 to 14.13)</td><td align="left" valign="top">4.06 (&#x2212;1.11 to 9.23)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;42-63</td><td align="left" valign="top">0.88 (0.69 to 1.10)</td><td align="left" valign="top">1.02 (0.87 to 1.19)</td><td align="left" valign="top"/><td align="left" valign="top">7.33 (0.78 to 13.89)</td><td align="left" valign="top">0.91 (&#x2212;3.61 to 5.42)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;&#x2265;63</td><td align="left" valign="top">1.10 (0.97 to 1.46)</td><td align="left" valign="top">1.24 (1.07 to 1.43)</td><td align="left" valign="top"/><td align="left" valign="top">&#x2212;2.97 (&#x2212;9.27 to 3.34)</td><td align="left" valign="top">&#x2212;8.88 (&#x2212;13.13 to &#x2212;4.62)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><italic>P</italic> value for the trend</td><td align="left" valign="top">.09</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top"/><td align="left" valign="top">.39</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">Smartphone screen time per 21 h per wk</td><td align="left" valign="top">1.00 (1.00 to 1.01)</td><td align="left" valign="top">1.00 (1.00 to 1.01)</td><td align="left" valign="top">.31</td><td align="left" valign="top">&#x2212;0.03 (&#x2212;0.10 to 0.05)</td><td align="left" valign="top">&#x2212;0.13 (&#x2212;0.19 to &#x2212;0.08)</td><td align="left" valign="top">.01</td></tr><tr><td align="left" valign="top" colspan="3">Smartphone unlocks (times per wk)</td><td align="left" valign="top">.56</td><td align="left" valign="top" colspan="2"/><td align="left" valign="top">.001</td></tr><tr><td align="left" valign="top">&#x2003;0-50</td><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top"/><td align="left" valign="top">Reference</td><td align="left" valign="top">Reference</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;50-150</td><td align="left" valign="top">1.07 (0.85 to 1.35)</td><td align="left" valign="top">1.12 (0.97 to 1.31)</td><td align="left" valign="top"/><td align="left" valign="top">13.66 (7.26 to 20.06)</td><td align="left" valign="top">1.89 (&#x2013;2.26 to 6.04)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;150-400</td><td align="left" valign="top">1.40 (1.10 to 1.79)</td><td align="left" valign="top">1.32 (1.13 to 1.55)</td><td align="left" valign="top"/><td align="left" valign="top">3.54 (&#x2212;3.45 to 10.54)</td><td align="left" valign="top">&#x2212;6.73 (&#x2212;11.18 to &#x2212;2.27)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;&#x2265;400</td><td align="left" valign="top">1.50 (1.17 to 1.93)</td><td align="left" valign="top">1.69 (1.43 to 1.98)</td><td align="left" valign="top"/><td align="left" valign="top">5.68 (&#x2212;1.78 to 13.15)</td><td align="left" valign="top">&#x2212;8.99 (&#x2212;13.72 to &#x2212;4.27)</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><italic>P</italic> value for the trend</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x2014;<sup><xref ref-type="table-fn" rid="table3fn4">d</xref></sup></td><td align="left" valign="top">.59</td><td align="left" valign="top">&#x003C;.001</td><td align="left" valign="top">&#x2014;</td></tr><tr><td align="left" valign="top">Smartphone unlocks per 50 times per wk</td><td align="left" valign="top">1.03 (1.01 to 1.04)</td><td align="left" valign="top">1.03 (1.02 to 1.04)</td><td align="left" valign="top">.30</td><td align="left" valign="top">&#x2212;0.03 (&#x2013;0.48 to 0.42)</td><td align="left" valign="top">&#x2212;0.77 (&#x2212;1.08 to &#x2212;0.46)</td><td align="left" valign="top">.002</td></tr></tbody></table><table-wrap-foot><fn id="table3fn1"><p><sup>a</sup>Adjusted for university year, race, registered permanent residence, whether the participants had siblings, parental educational attainment, current smoking, current drinking, physical activity, rational diet, and social support).</p></fn><fn id="table3fn2"><p><sup>b</sup>OR: odds ratio.</p></fn><fn id="table3fn3"><p><sup>c</sup>MPATS: Mobile Phone Addiction Tendency Scale.</p></fn><fn id="table3fn4"><p><sup>d</sup>Not applicable.</p></fn></table-wrap-foot></table-wrap></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>This study systematically revealed the diverse associations between both smartphone addiction and objectively measured smartphone use and sleep among university students. Specifically, we found significant negative associations between smartphone addiction and both sleep quality and duration. Excessive objectively measured screen time and unlocks were significantly and positively associated with poor sleep and shorter sleep duration.</p></sec><sec id="s4-2"><title>Comparison With Other Studies</title><p>Despite the growing number of studies on the association between smartphone use and sleep, previous research has been mainly siloed, focusing exclusively on the effect of either smartphone addiction or objectively measured smartphone use on sleep quality. For instance, a systematic review revealed a significantly increased risk of poor sleep in individuals with smartphone addiction [<xref ref-type="bibr" rid="ref51">51</xref>]. In a complementary nationally representative twin study, self-reported problematic digital technology use remained significantly correlated with poor sleep after accounting for confounders [<xref ref-type="bibr" rid="ref52">52</xref>]. More recently, a study among university students uncovered positive associations between smartphone addiction and both bedtime procrastination and poor sleep [<xref ref-type="bibr" rid="ref53">53</xref>]. Kaya et al [<xref ref-type="bibr" rid="ref7">7</xref>] reported a significant relationship between self-reported smartphone use and poor sleep quality among university students using the Smartphone Addiction Scale&#x2013;Short Version to assess smartphone addiction. Another study showed that smartphone addiction was linked to sleep quality and sleep duration [<xref ref-type="bibr" rid="ref54">54</xref>]. The results of this study on the association between smartphone addiction and sleep are consistent with the findings of these studies.</p><p>In recent years, studies have increasingly focused on associations between smartphone use behaviors and sleep outcomes, yet reported findings remain inconsistent. For instance, a small-sample study using daily self-report smartphone use data found no association between smartphone talk time or screen time and sleep quality and duration [<xref ref-type="bibr" rid="ref15">15</xref>]. In contrast, a larger study among adults revealed that self-reported daily smartphone use time was linked to poorer sleep quality, whereas unlocks showed no association with sleep parameters [<xref ref-type="bibr" rid="ref55">55</xref>]. However, most existing research relies on self-reported smartphone use data, which are susceptible to recall bias and misclassification. The inconsistencies across findings highlight the critical need for more objective measures of smartphone screen time and unlocks to capture the true associations between smartphone use and sleep. To date, few studies have leveraged objectively measured smartphone use data to explore associations with sleep [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], and no consensus has been reached regarding these relationships. A study directly measured smartphone screen time in 136 participants via a tracking app and found that longer smartphone screen time was associated with poorer sleep efficiency and shorter sleep duration [<xref ref-type="bibr" rid="ref56">56</xref>]. A Chinese study tracked participants&#x2019; smartphone use using the same method and indicated that each minute of daytime smartphone use was related to a 0.07-minute reduction in same-night total sleep time but unrelated to sleep efficiency and postsleep awakenings [<xref ref-type="bibr" rid="ref57">57</xref>]. Only 1 recent study identified smartphone screen time and unlocks as significant predictors of total sleep time, albeit concluding that this effect was minimal [<xref ref-type="bibr" rid="ref13">13</xref>]. All 3 of these studies concur that excessive objectively measured smartphone use reduces sleep duration while showing less consistency in their findings regarding the impact on sleep quality, particularly sleep efficiency. Notably, our study confirmed that excessive smartphone screen time and unlocks were associated with reductions in sleep duration by 6.66 minutes and 9.90 minutes per night, respectively, as well as an increased risk of poor sleep.</p><p>Novelly, an inverted U&#x2013;shaped nonlinear association was observed between smartphone screen time and reduction in sleep duration. The inverted U&#x2013;shaped relationship was matched by a corresponding delay in sleep offset. No previous studies have focused on the dose-response relationship between smartphone use and sleep, although some support can be drawn from several studies on presleep smartphone use. For example, a study that objectively assessed smartphone use before sleep using a tracking app found that using smartphones before sleep for longer than usual was associated with sleeping earlier and sleeping longer among adolescents [<xref ref-type="bibr" rid="ref58">58</xref>], suggesting a potentially positive effect on sleep duration. A recent study showed that total screen use in the 2 hours before bedtime was associated with delayed sleep onset but not with total sleep time [<xref ref-type="bibr" rid="ref9">9</xref>]. Similarly, Exelmans and Van den Bulck [<xref ref-type="bibr" rid="ref59">59</xref>] suggested that bedtime smartphone use predicted later rise times, which may indicate a compensation behavior for missed sleep. Collectively, these 3 studies suggest that the impact of smartphone use on sleep duration may be less pronounced than that shown in some studies based on self-reported smartphone use data. Our study further identified an inverted U&#x2013;shaped relationship between average smartphone use time and sleep duration via RCS regression, providing an important contribution to the existing literature. However, as this was a cross-sectional study that assessed associations at a single time point, longitudinal cohort research is critical to validate causality and assess long-term trajectories.</p><p>In this study, the &#x03B2; coefficient for the association between both smartphone screen time and unlocks and sleep duration was more pronounced in female than in male individuals. Sex differences in the association may stem from sex-specific preferences for smartphone apps. Compared with male individuals, female individuals exhibit stronger preferences for social media platforms [<xref ref-type="bibr" rid="ref60">60</xref>], which are characterized by high unlock frequencies. Social media platforms are highly interactive, marked by frequent user engagement. The captivating content on these platforms is more likely to induce emotional arousal and subsequent sleep onset delay. This study did not evaluate sex-specific app preferences among students. Hence, future research should gather detailed data on the use of apps to further explore sex-specific differences and underlying mechanisms.</p></sec><sec id="s4-3"><title>Possible Explanations of the Associations</title><p>Several reasons may underlie the association between smartphone use and sleep. The reduction in sleep duration among university students with high smartphone use levels can be mechanistically explained through several pathways. The negative impact of smartphone use on sleep duration is consistent with the time displacement hypothesis [<xref ref-type="bibr" rid="ref18">18</xref>], whereas the impairments in sleep quality can be explained by the combined effects of screen-emitted light on melatonin suppression [<xref ref-type="bibr" rid="ref20">20</xref>] and psychological arousal from engaging content [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]. Furthermore, the association between smartphone addiction and sleep may additionally involve individuals&#x2019; negative cognitive appraisals of their use, such as perceived loss of control over smartphone use and guilt regarding excessive use, which may exacerbate sleep impairment. However, the reduction in sleep duration observed among students with low smartphone use levels represents a key novelty of this study, and it may be attributed to the following mechanisms. First, from a psychosocial perspective, smartphones have become highly integrated into the social interactions and academic activities of university students. Excessively low smartphone use may indicate potential difficulties in social connection or emotion regulation for individuals [<xref ref-type="bibr" rid="ref61">61</xref>], and these factors are established risk factors for sleep, thus accounting for the observed reduction in sleep duration in the context of low smartphone use. Second, from a theoretical standpoint, the conservation of resources theory posits that technologies such as smartphones play a crucial role in the acquisition and maintenance of psychosocial resources [<xref ref-type="bibr" rid="ref62">62</xref>]. Two studies even showed that smartphone nonusers are generally more prone to experiencing depression and anxiety [<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]. Another study measured objective smartphone use in the context of the relationship between smartphone use and well-being, showing that people with intermediate smartphone use had better mood and lower loneliness than those with low smartphone use [<xref ref-type="bibr" rid="ref65">65</xref>]. Third, in terms of sleep behavior patterns, individuals with low smartphone use may exhibit an earlier sleep phase, especially for those who rise early, which can result in objectively shorter total sleep duration. An objective measurement study using a wearable sleep and activity tracker, smartphone-delivered ecological momentary assessments, and passive smartphone use tracking also reported a similar pattern [<xref ref-type="bibr" rid="ref65">65</xref>], finding that individuals with low bedtime smartphone use had earlier wake times (9:25 AM; &#x2013;1 hour, 30 minutes to +1 hour, 30 minutes) than high bedtime smartphone users (10:08 AM; &#x2013;1 hour, 49 minutes to +1 hour, 49 minutes).</p></sec><sec id="s4-4"><title>Limitations</title><p>First, although the models included a wide range of demographic and lifestyle factors, some confounding variables may have remained unaccounted for, potentially influencing the study findings. Second, sleep quality and duration were assessed using a retrospective self-report questionnaire, which may result in recall bias. Future studies would benefit from incorporating objective sleep measurements to triangulate the findings. Third, due to the cross-sectional study design, causal inferences regarding the relationship between smartphone use and sleep cannot be made. Future longitudinal studies are warranted to address it. Fourth, the generalizability of our findings may be limited by the exclusive focus on university students in China and the uneven sex distribution in the study sample. Fifth, although this study objectively measured smartphone use time and frequency via smartphone screenshot, data in this study still lack granularity regarding temporal dynamics (eg, distribution over the day or week) and functional variation (eg, social media, entertainment, education, or work). These details may be important for understanding the nuanced associations between smartphone use and sleep. Sixth, although the multilevel model treating class membership as a random effect yielded substantially unchanged results, this study did not account for clustering effects stemming from shared living or social environments (eg, classes, dormitories, and clubs). Future research could address these clustering effects by implementing simple random sampling methods, which would help minimize potential biases arising from nonindependent observations.</p></sec><sec id="s4-5"><title>Conclusions</title><p>This study found significant associations between smartphone addiction, excessive objectively measured screen time, and unlocks and both poor sleep and shorter sleep duration. RCS analyses revealed different nuanced dose-response relationships, with an inverted U&#x2013;shaped association observed between smartphone screen time and sleep duration.</p></sec></sec></body><back><notes><sec><title>Funding</title><p>This research was funded by the Natural Science Basic Research Program of Shaanxi Province (2024JC-YBQN-0943 and 2025JC-YBMS-1014).</p></sec><sec><title>Data Availability</title><p>The datasets generated or analyzed during this study are available from the corresponding author on reasonable request.</p></sec></notes><fn-group><fn fn-type="con"><p>JY and XT contributed to the conception or design of the study and drafted the manuscript. ZL, YG, and HY contributed to the acquisition, analysis, or interpretation of the data for this work. YZ provided a critical review of the manuscript. All authors contributed to the manuscript and have read and approved the published version.</p></fn><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">ASSS</term><def><p>Adolescent Social Support Scale</p></def></def-item><def-item><term id="abb2">CONSORT-EHEALTH</term><def><p>Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online Telehealth</p></def></def-item><def-item><term id="abb3">MPATS</term><def><p>Mobile Phone Addiction Tendency Scale</p></def></def-item><def-item><term id="abb4">OR</term><def><p>odds ratio</p></def></def-item><def-item><term id="abb5">PSQI</term><def><p>Pittsburgh Sleep Quality Index</p></def></def-item><def-item><term id="abb6">RCS</term><def><p>restricted cubic splines</p></def></def-item><def-item><term id="abb7">STROBE</term><def><p>Strengthening the Reporting of Observational Studies in 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KB"/></supplementary-material><supplementary-material id="app4"><label>Checklist 1</label><p>CONSORT-EHEALTH checklist.</p><media xlink:href="mental_v12i1e77796_app4.pdf" xlink:title="PDF File, 421 KB"/></supplementary-material></app-group></back></article>