<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMH</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Ment Health</journal-id>
      <journal-title>JMIR Mental Health</journal-title>
      <issn pub-type="epub">2368-7959</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v10i1e43929</article-id>
      <article-id pub-id-type="pmid">37103983</article-id>
      <article-id pub-id-type="doi">10.2196/43929</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Validation of the Attitudes Towards Psychological Online Interventions Questionnaire Among Black Americans: Cross-cultural Confirmatory Factor Analysis</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Torous</surname>
            <given-names>John</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Pardini</surname>
            <given-names>Susanna</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Chow</surname>
            <given-names>Phil</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Ellis</surname>
            <given-names>Donovan Michael</given-names>
          </name>
          <degrees>MA</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9888-1613</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Anderson</surname>
            <given-names>Page Lyn</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Psychology</institution>
            <institution>Georgia State University</institution>
            <addr-line>Urban Life Bldg, 11th Floor</addr-line>
            <addr-line>140 Decatur Street</addr-line>
            <addr-line>Atlanta, GA, 30303</addr-line>
            <country>United States</country>
            <phone>1 404 413 6258</phone>
            <email>panderson@gsu.edu</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3811-9088</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Psychology</institution>
        <institution>Georgia State University</institution>
        <addr-line>Atlanta, GA</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Page Lyn Anderson <email>panderson@gsu.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2023</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>27</day>
        <month>4</month>
        <year>2023</year>
      </pub-date>
      <volume>10</volume>
      <elocation-id>e43929</elocation-id>
      <history>
        <date date-type="received">
          <day>1</day>
          <month>11</month>
          <year>2022</year>
        </date>
        <date date-type="rev-request">
          <day>23</day>
          <month>2</month>
          <year>2023</year>
        </date>
        <date date-type="rev-recd">
          <day>5</day>
          <month>3</month>
          <year>2023</year>
        </date>
        <date date-type="accepted">
          <day>6</day>
          <month>3</month>
          <year>2023</year>
        </date>
      </history>
      <copyright-statement>©Donovan Michael Ellis, Page Lyn Anderson. Originally published in JMIR Mental Health (https://mental.jmir.org), 27.04.2023.</copyright-statement>
      <copyright-year>2023</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Mental Health, is properly cited. The complete bibliographic information, a link to the original publication on https://mental.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://mental.jmir.org/2023/1/e43929" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Acceptability of digital mental health interventions is a significant predictor of treatment-seeking behavior and engagement. However, acceptability has been conceptualized and operationalized in various ways, which decreases measurement precision and leads to heterogeneous conclusions about <italic>acceptability</italic>. Standardized self-report measures of acceptability have been developed, which have the potential to ameliorate these problems, but none have demonstrated evidence for validation among Black communities, which limits our understanding of attitudes toward these interventions among racially minoritized groups with well-documented barriers to mental health treatment.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aims to examine the psychometric validity and reliability of one of the first and most widely used measures of acceptability, the Attitudes Towards Psychological Online Interventions Questionnaire, among a Black American sample.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>Participants (N=254) were recruited from a large southeastern university and the surrounding metropolitan area and completed the self-report measure via a web-based survey. A confirmatory factor analysis using mean and variance adjusted weighted least squares estimation was conducted to examine the validity of the underlying hierarchical 4-factor structure proposed by the original authors of the scale. An alternative, hierarchical 2-factor structure model and bifactor model were examined for comparative fit.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>The findings indicated that the bifactor model demonstrated a superior fit (comparative fit index=0.96, Tucker-Lewis index=0.94, standardized root mean squared residual=0.03, and root mean square error of approximation=0.09) compared with both 2- and 4-factor hierarchical structure models.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>The findings suggest that, within a Black American sample, there may be greater utility in interpreting the Attitudes Towards Psychological Online Interventions Questionnaire subscales as attitudinal constructs that are distinct from the global <italic>acceptability</italic> factor. The theoretical and practical implications for culturally responsive measurements were explored.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>acceptability</kwd>
        <kwd>Black American</kwd>
        <kwd>iCBT</kwd>
        <kwd>internet-based cognitive behavioral therapy</kwd>
        <kwd>digital treatment</kwd>
        <kwd>confirmatory factor analysis</kwd>
        <kwd>bifactor model</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>Black communities face persistent barriers to mental health treatment, including cost, accessibility, and stigma [<xref ref-type="bibr" rid="ref1">1</xref>-<xref ref-type="bibr" rid="ref3">3</xref>]. Internet-based psychological interventions that implement evidence-based techniques, including psychoeducation, behavioral activation, mindfulness strategies, and symptom tracking [<xref ref-type="bibr" rid="ref4">4</xref>], may prove useful for improving equitable access to mental health treatment as they are often more cost-effective [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref6">6</xref>], private [<xref ref-type="bibr" rid="ref7">7</xref>], and readily accessible [<xref ref-type="bibr" rid="ref8">8</xref>]. Digital interventions that are empirically driven and incorporate elements of cognitive behavioral therapy are typically referred to as internet-based cognitive behavioral therapy (iCBT) [<xref ref-type="bibr" rid="ref9">9</xref>]. People benefit from iCBT when paired with therapist support or used alone, although the magnitude of the effect is often higher for programs with therapist assistance [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>] (for more conservative findings on the comparative benefit of therapist support with iCBT, see the study by Bernstein et al [<xref ref-type="bibr" rid="ref12">12</xref>]). Although iCBT programs are effective for a variety of anxiety, mood, and substance use disorders [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>], studies have consistently reported their underutilization by the public [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>].</p>
      </sec>
      <sec>
        <title>Acceptability of iCBT</title>
        <p>Studies examining this research-to-practice gap have revealed a complex picture of user acceptance of digital mental health interventions. Although therapist-supported iCBT is generally rated as more acceptable than self-guided programs [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref18">18</xref>], the overall willingness to use iCBT is low. In one study, 16% of non–treatment-seeking adults reported a willingness to consider using a digital mental health intervention to address a mental health concern [<xref ref-type="bibr" rid="ref19">19</xref>], and another study reported that only 12% of participants were “definitely interested” in internet-based treatment [<xref ref-type="bibr" rid="ref20">20</xref>]. Overall, people reported that they significantly preferred face-to-face therapy over iCBT and other digital mental health interventions [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>].</p>
        <p>A problem in this budding literature is that the construct of acceptability has been defined in a variety of ways, which may contribute to heterogeneous results regarding consumer attitudes toward iCBT [<xref ref-type="bibr" rid="ref22">22</xref>]. Retrospective study outcomes, such as treatment satisfaction, engagement, usability, and feasibility, are often used interchangeably with acceptability [<xref ref-type="bibr" rid="ref23">23</xref>]. Other researchers propose more prospective metrics, conceptualizing acceptability as “cognitively based, positive attitudes towards such interventions” that aim to predict treatment seeking [<xref ref-type="bibr" rid="ref24">24</xref>]. Acceptability has sometimes been operationalized with measures of similar constructs, such as outcome expectancy—the expectation that one will benefit from treatment [<xref ref-type="bibr" rid="ref25">25</xref>]. In some studies, acceptability was operationalized using single Likert scale items measuring willingness to use an intervention [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>], and in other studies, researchers developed their own measure of acceptability [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. The lack of precision in conceptualization and measurement may explain why conclusions about the acceptability of iCBT vary widely across studies.</p>
        <p>A total of 6 self-report measures of consumer acceptability of digital mental health interventions now exist, with evidence of their psychometric properties and factor structure [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref33">33</xref>]. However, reflecting existing heterogeneity in the literature, these measures operationalize acceptability in various ways. The Attitudes Towards Psychological Online Interventions (APOI) questionnaire conceptualizes acceptability as a set of positive and negative appraisals and is designed to be used with various forms of digital mental health interventions [<xref ref-type="bibr" rid="ref24">24</xref>]. The e-Therapy Attitudes and Process Questionnaire [<xref ref-type="bibr" rid="ref29">29</xref>] includes items specifically related to users’ anticipated engagement with and short-term adherence to digital interventions. The Online Psychoeducational Intervention–Brief Attitudes Scale [<xref ref-type="bibr" rid="ref32">32</xref>] is an abbreviated measure of attitudes (5 items) that makes the conceptual distinction that attitudes toward web-based psychoeducational interventions should incorporate elements of both psychotherapy and learning methods. In addition, 3 measures have been developed to assess working alliances in different digital contexts, akin to the therapeutic alliance fostered in face-to-face therapy [<xref ref-type="bibr" rid="ref34">34</xref>]. The Working Alliance Inventory for guided internet interventions [<xref ref-type="bibr" rid="ref30">30</xref>] measures the perception of an emotional attachment or collaborative bond with a digital mental health intervention, and the Working Alliance Inventory applied to virtual and augmented reality [<xref ref-type="bibr" rid="ref33">33</xref>] measures participant comfort and trust in a virtual reality environment. Similarly, the Virtual Therapist Alliance Scale [<xref ref-type="bibr" rid="ref31">31</xref>] measures perceptions of the therapeutic alliance with digital therapist avatars common to automated virtual reality exposure therapies. <xref ref-type="table" rid="table1">Table 1</xref> shows the characteristics of the acceptability measures.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Measures of acceptability toward digital mental health interventions.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="210"/>
            <col width="410"/>
            <col width="150"/>
            <col width="230"/>
            <thead>
              <tr valign="top">
                <td>Study</td>
                <td>Title</td>
                <td>Abbreviation</td>
                <td>Intervention modality</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Clough et al [<xref ref-type="bibr" rid="ref29">29</xref>], 2019</td>
                <td>e-Therapy Attitudes and Process Questionnaire</td>
                <td>eTAP</td>
                <td>All</td>
              </tr>
              <tr valign="top">
                <td>Gómez Penedo et al [<xref ref-type="bibr" rid="ref30">30</xref>], 2020</td>
                <td>Working Alliance Inventory for Guided Internet Interventions</td>
                <td>WAI-I</td>
                <td>Guided interventions</td>
              </tr>
              <tr valign="top">
                <td>Miloff et al [<xref ref-type="bibr" rid="ref31">31</xref>], 2020</td>
                <td>Virtual Therapist Alliance Scale</td>
                <td>VTAS</td>
                <td>Augmented and virtual reality</td>
              </tr>
              <tr valign="top">
                <td>Miragall et al [<xref ref-type="bibr" rid="ref33">33</xref>], 2015</td>
                <td>Working Alliance Inventory Applied to Virtual and Augmented Reality</td>
                <td>WAI-VAR</td>
                <td>Augmented and virtual reality</td>
              </tr>
              <tr valign="top">
                <td>Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>], 2015</td>
                <td>Attitudes Towards Psychological Online Interventions Questionnaire</td>
                <td>APOI</td>
                <td>All</td>
              </tr>
              <tr valign="top">
                <td>Teles et al [<xref ref-type="bibr" rid="ref32">32</xref>], 2021</td>
                <td>Online Psychoeducational Intervention—Brief Attitudes Scale</td>
                <td>OPI-BAS</td>
                <td>Psychoeducation</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
      </sec>
      <sec>
        <title>Racially Minoritized Communities Are Underrepresented in Acceptability Research</title>
        <p>Further complicating matters are the dearth of acceptability research that is inclusive of ethnically or racially minoritized communities. In 1 meta-analysis, 62 of 64 randomized controlled trials examining the efficacy and acceptability of iCBT did not include (or did not report) racial minorities in their studies [<xref ref-type="bibr" rid="ref13">13</xref>]. All but one [<xref ref-type="bibr" rid="ref33">33</xref>] of the existing measures of consumer attitudes toward digital mental health interventions have collected data from White majority (and predominantly European language) samples [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref32">32</xref>], including the first and most highly cited measure of acceptability toward digital mental health interventions, the APOI questionnaire [<xref ref-type="bibr" rid="ref24">24</xref>]. The APOI was developed with German-speaking participants who reported mild to moderate depression (N=1013) and were recruited from outpatient clinics, web-based health forums, and health insurance referrals.</p>
        <p>No research to date has evaluated the reliability or validity of the APOI scale among racially or ethnically minoritized communities, including Black Americans. This is highly problematic because even though Black communities may disproportionately benefit from the advantages afforded by iCBT and related digital mental health interventions, it is unknown whether the APOI demonstrates good psychometric properties in this population.</p>
      </sec>
      <sec>
        <title>This Study</title>
        <p>This study addresses this problem by assessing the psychometric properties of the APOI questionnaire in a sample of Black Americans. Using confirmatory factor analyses, this study examined whether the APOI demonstrates reliability and construct validity within a Black population. In this study, 2 measurement models were examined using 16 ordered categorical (ordinal) response items retained in the exploratory factor analysis of the APOI. The first model presents a 2-factor, hierarchical measurement model (positive and negative subfactors) distinct from the 4-factor hierarchical model proposed by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>]. Given considerations for equivalent models [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>] modification indexes will be reviewed to examine new and replicative factor structures to illuminate the underlying construct of <italic>acceptability</italic>.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Recruitment</title>
        <p>Participants were self-identified Black or African American adults (N=254 participants). The participants ranged in age from 18 to 85 (mean 27.11, SD 13.40) years and were predominantly women (172.7/254, 68%), single (167.6/254, 66%), and highly educated (at least 70% had some college education; see <xref ref-type="table" rid="table2">Table 2</xref> for more demographic and clinical characteristics of the sample). Participants were recruited from 2 primary sources: students recruited from the participant pool of a southeastern university in an urban setting who received course credit for their participation and community participants who were solicited in public places throughout the metropolitan area (eg, parks) and had the opportunity to enter a raffle for a US $25 Amazon gift card.</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Demographics and clinical characteristics of participants.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="550"/>
            <col width="0"/>
            <col width="420"/>
            <thead>
              <tr valign="top">
                <td colspan="3">Variables</td>
                <td>Values</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">Age (years; n=254), mean (SD)</td>
                <td>27.11 (13.40)</td>
              </tr>
              <tr valign="top">
                <td colspan="4">
                  <bold>Sex (n=254), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Male</td>
                <td colspan="2">82 (32.3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Female</td>
                <td colspan="2">172 (67.7)</td>
              </tr>
              <tr valign="top">
                <td colspan="4">
                  <bold>Sexual identity (n=252), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Heterosexual</td>
                <td colspan="2">210 (83.3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Lesbian, gay, and bisexual</td>
                <td colspan="2">36 (14.3)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Self-identify</td>
                <td colspan="2">6 (2.4)</td>
              </tr>
              <tr valign="top">
                <td colspan="4">
                  <bold>Current education status (n=253), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>High school</td>
                <td colspan="2">1 (0.4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Some college or currently in college</td>
                <td colspan="2">173 (68.1)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Graduate or professional degree</td>
                <td colspan="2">5 (2.0)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Nondegree student or other</td>
                <td colspan="2">3 (1.2)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Nonstudent<sup>a</sup></td>
                <td colspan="2">71 (28.0)</td>
              </tr>
              <tr valign="top">
                <td colspan="4">
                  <bold>Relationship status (n=252), n (%)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Single</td>
                <td colspan="2">166 (65.9)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Serious dating or committed relationship</td>
                <td colspan="2">55 (21.8)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Married or civil union</td>
                <td colspan="2">16 (6.4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Separated, divorced, or widowed</td>
                <td colspan="2">15 (6.0)</td>
              </tr>
              <tr valign="top">
                <td colspan="4">
                  <bold>Symptom severity,</bold>
                  <bold>mean (SD)</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>DASS<sup>b</sup>—total (n=243)</td>
                <td colspan="2">29.58 (20.84)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>DASS—depression (n=250)</td>
                <td colspan="2">8.99 (8.49)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>DASS—anxiety (n=249)</td>
                <td colspan="2">8.35 (7.10)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>DASS—stress (n=250)</td>
                <td colspan="2">11.96 (7.88)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>Reflects current noneducational status but does not indicate the highest level of education completed (ie, may include college graduates).</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>DASS: Depression Anxiety Stress Scale.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Procedure</title>
        <p>Participants completed a survey developed via the Qualtrics web-based platform as part of an experimental study assessing the impact of treatment rationale on the acceptability of iCBT. Participants were randomly assigned via Qualtrics (1:1 allocation) to read either a treatment rationale or definition of iCBT (see the study by Ellis and Anderson [<xref ref-type="bibr" rid="ref37">37</xref>] for full details). The APOI questionnaire was administered as a primary measure of acceptability. The Depression, Anxiety, and Stress Scale-21 items (DASS-21) was used to characterize the sample, as experiences of depression and anxiety have been linked to mental health treatment–seeking attitudes [<xref ref-type="bibr" rid="ref38">38</xref>] and to provide comparative evidence to Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>] who recruited participants with mild to moderate depression.</p>
        <p>All the data were collected on the web and will be made available upon request.</p>
      </sec>
      <sec>
        <title>Measures</title>
        <p>The APOI questionnaire [<xref ref-type="bibr" rid="ref24">24</xref>] is a measure of attitudes toward digital mental health interventions that, for the purposes of this project, was modified to reference therapist-assisted iCBT. The development of the APOI included both exploratory and confirmatory factor analyses to identify clustering of latent constructs, resulting in 16 items comprising four subscales measuring attitudes toward psychological web-based interventions, which are as follows: (1) skepticism and perception of risk (SKE), which measures negative attitudes concerning the efficacy and security of a psychological web-based intervention; (2) confidence in effectiveness (CON), which measures positive attitudes concerning the utility and credibility of a psychological web-based intervention; (3) technologization threat (TET), which measures negative attitudes toward the lack of personal contact and the remote nature of the intervention; and (4) anonymity benefits (ABE), which measures positive attitudes related to increased privacy. Participants rate their agreement with each item (eg, “I have the feeling that iCBT can help me.”) on a 5-point Likert scale (1=totally agree to 5=totally disagree). Positively valenced items were reverse coded. The total scores ranged from 16 to 80, with higher scores indicating more positive attitudes toward iCBT. The APOI demonstrated strong overall internal consistency (Cronbach α=.77) and showed evidence of construct validity in a sample of 1013 participants [<xref ref-type="bibr" rid="ref24">24</xref>].</p>
        <p>The DASS-21 [<xref ref-type="bibr" rid="ref39">39</xref>] is a measure of mental illness comprising 3 subscales: depression, anxiety, and stress. Participants rated each item on a 4-point Likert scale (0=never to 3=always). Sum scores were computed by adding the scores across items and multiplying by 2. Scores on the total DASS-21 scale ranged from 0 to 126, with higher scores indicating more distress or impairment. Scores for each subscale were determined by summing the scores for the relevant 7 items and multiplying by 2 (range 0-42). The DASS-21 demonstrates strong convergent validity with both the Beck Anxiety Inventory (<italic>r</italic>=0.81) and Beck Depression Inventory (<italic>r</italic>=0.74), indicating a satisfactory ability to discriminate between anxiety and depressive symptoms [<xref ref-type="bibr" rid="ref40">40</xref>]. The DASS-21 was normed on a nonclinical sample (N=717), and subsequent research has supported the validity and reliability of the DASS-21 across racial groups, including Black Americans (subscales: Cronbach α=.81−.88 [<xref ref-type="bibr" rid="ref41">41</xref>]).</p>
      </sec>
      <sec>
        <title>Statistical Analysis</title>
        <p>The variables used for the factor analysis are listed in <xref ref-type="table" rid="table3">Table 3</xref>. See <xref ref-type="table" rid="table4">Tables 4</xref> and <xref ref-type="table" rid="table5">5</xref> for the interitem correlation matrix and descriptive statistics.</p>
        <p>Confirmatory factor analyses were performed using Mplus (version 8.4; Muthén &#38; Muthén) with a sample of Black American adults (N=254) to examine the cross-cultural equivalence of the factor structure derived from the final set of 16 items indicated in the study by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>]. The weighted least squares means and variance adjusted (WLSMV) estimation method was used to analyze the covariance matrix structure of ordinal items. Several indices were used to evaluate the model fit: the discrepancy chi-square statistic (df≤5), standardized root mean squared residual (SRMR; SRMR≤0.08), root mean square error of approximation (RMSEA; RMSEA≤0.08), comparative fit index (CFI; CFI≥0.90), and Tucker-Lewis index (TLI; TLI≥0.90), which are commonly recommended at the indicated thresholds [<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref44">44</xref>]. Latent variables were scaled by fixing the latent variances to 1, which allowed all indicator factor loadings to be estimated. Finally, reliability analyses of the APOI were conducted by calculating the internal consistency (Cronbach α) and corrected item-total correlations (discrimination) to facilitate comparisons with reliability metrics reported in the original publication.</p>
        <p>In model 1, we examined a 2-factor, hierarchical confirmatory measurement model (2 first-order factors loading on 1 second-order global factor). We posited that the set of attitudes endorsed on the APOI would indicate a “positive attitudes towards internet-based treatments” latent factor as well as a “negative attitudes towards internet-based treatments” latent factor. Indicators drawn from the confidence in effectiveness (CON) and anonymity benefits (ABE) subscales comprise positive attitudes toward iCBT and were tested to examine statistically significant loading onto the “positive” latent factor. Indicators derived from the skepticism and perception of risk (SKE) and technologization threat (TET) subscales of the APOI comprise negative attitudes and were tested for statistically significant loading onto the “negative” latent factor. Both “positive” and “negative” first-order factors loaded onto the second-order global factor (termed <italic>Acceptability</italic> for the purposes of this study; <xref rid="figure1" ref-type="fig">Figure 1</xref>).</p>
        <p>In model 2, we attempted a replication of the 4-factor, hierarchical confirmatory measurement model (4 first-order factors loading on 1 second-order global factor) proposed in the study by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>]. Indicators drawn from the 4 subscales were modeled per the provided confirmatory factor analysis specifications [<xref ref-type="bibr" rid="ref24">24</xref>]. All 4 first-order factors (CON, ABE, SKE, and TET) were loaded onto the second-order global factor acceptability (<xref rid="figure2" ref-type="fig">Figure 2</xref>).</p>
        <p>If neither hypothesized model 1 nor model 2 demonstrates adequate model fit, the modification fit indexes provided by the WLSMV estimation will be reviewed, and the comparative fit of a third alternative model (model 3) will be examined.</p>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Attitudes Towards Psychological Online Interventions Questionnaire: subscale and item descriptions<sup>a</sup>.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="290"/>
            <col width="680"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Measure name and scale or item label</td>
                <td>Description</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="2">
                  <bold>Confidence in effectiveness subscale<sup>b</sup></bold>
                </td>
                <td>Measures positive attitudes concerning the efficacy and credibility of therapist-assisted iCBT<sup>c</sup></td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>CON1</td>
                <td>A therapist-assisted iCBT program can help me to recognize the issues that I have to challenge.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>CON2</td>
                <td>I have the feeling that a therapist-assisted iCBT can help me.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>CON3</td>
                <td>A therapist-assisted iCBT program can inspire me to better approach my problems.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>CON4</td>
                <td>I believe that the concept of therapist-assisted iCBT programs makes sense.</td>
              </tr>
              <tr valign="top">
                <td colspan="2">
                  <bold>Anonymity benefits subscale<sup>b</sup></bold>
                </td>
                <td>Measures positive attitudes related to the privacy and confidentiality of using a therapist-assisted iCBT</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>ABE1</td>
                <td>A therapist-assisted iCBT program is more confidential and discreet than visiting a therapist.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>ABE2</td>
                <td>By using a therapist-assisted iCBT program, I can reveal my feelings more easily than with a therapist.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>ABE3</td>
                <td>I would be more likely to tell my friends that I use a therapist-assisted iCBT program than that I visit a therapist.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>ABE4</td>
                <td>By using a therapist-assisted iCBT program, I do not have to fear that someone will find out that I have psychological problems.</td>
              </tr>
              <tr valign="top">
                <td colspan="2">
                  <bold>Skepticism and perception of risk subscale<sup>d</sup></bold>
                </td>
                <td>Measures negative attitudes concerning the efficacy and security of a therapist-assisted iCBT</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>SKE1</td>
                <td>Using therapist-assisted iCBT programs, I do not expect long-term effectiveness.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>SKE2</td>
                <td>Using therapist-assisted iCBT programs, I do not receive professional support.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>SKE3</td>
                <td>It is difficult to implement the suggestions of a therapist-assisted iCBT effectively in everyday life.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>SKE4</td>
                <td>Therapist-assisted iCBT programs could increase isolation and loneliness.</td>
              </tr>
              <tr valign="top">
                <td colspan="2">
                  <bold>Technologization threat subscale<sup>d</sup></bold>
                </td>
                <td>Measures negative attitudes related to the independent and remote nature of therapist-assisted iCBT</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>TET1</td>
                <td>In crisis situations, a therapist can help me better than a therapist-assisted iCBT program.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>TET2</td>
                <td>I learn skills to better manage my everyday life from a therapist rather than from a therapist-assisted iCBT program.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>TET3</td>
                <td>I am more likely to stay motivated with a therapist than when using a therapist-assisted iCBT program.</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>TET4</td>
                <td>I do not understand therapeutic concepts as well with a therapist-assisted iCBT.</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table3fn1">
              <p><sup>a</sup>Response scale (1=totally disagree to 5=totally agree).</p>
            </fn>
            <fn id="table3fn2">
              <p><sup>b</sup>Higher scores represent greater acceptability.</p>
            </fn>
            <fn id="table3fn3">
              <p><sup>c</sup>iCBT: internet-based cognitive behavioral therapy.</p>
            </fn>
            <fn id="table3fn4">
              <p><sup>d</sup>Higher scores indicate lower acceptability.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table4">
          <label>Table 4</label>
          <caption>
            <p> Bivariate correlations between the 16 Attitudes Towards Psychological Online Interventions items.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="200"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <thead>
              <tr valign="top">
                <td>Variable</td>
                <td>1</td>
                <td>2</td>
                <td>3</td>
                <td>4</td>
                <td>5</td>
                <td>6</td>
                <td>7</td>
                <td>8</td>
                <td>9</td>
                <td>10</td>
                <td>11</td>
                <td>12</td>
                <td>13</td>
                <td>14</td>
                <td>15</td>
                <td>16</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>CON<sup>a</sup>1</td>
                <td>1</td>
                <td>—<sup>b</sup></td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>CON2</td>
                <td>0.74</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>CON3</td>
                <td>0.76</td>
                <td>0.79</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>CON4</td>
                <td>0.71</td>
                <td>0.65</td>
                <td>0.75</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>ABE<sup>c</sup>1</td>
                <td>0.38</td>
                <td>0.46</td>
                <td>0.47</td>
                <td>0.41</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>ABE2</td>
                <td>0.37</td>
                <td>0.42</td>
                <td>0.43</td>
                <td>0.44</td>
                <td>0.72</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>ABE3</td>
                <td>0.20</td>
                <td>0.34</td>
                <td>0.26</td>
                <td>0.25</td>
                <td>0.53</td>
                <td>0.56</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>ABE4</td>
                <td>0.38</td>
                <td>0.41</td>
                <td>0.40</td>
                <td>0.45</td>
                <td>0.61</td>
                <td>0.58</td>
                <td>0.66</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>SKE<sup>d</sup>1</td>
                <td>−0.05</td>
                <td>−0.10</td>
                <td>−0.07</td>
                <td>0.01</td>
                <td>−0.27</td>
                <td>−0.31</td>
                <td>−0.15</td>
                <td>−0.17</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>SKE2</td>
                <td>−0.01</td>
                <td>−0.10</td>
                <td>−0.02</td>
                <td>0.02</td>
                <td>−0.12</td>
                <td>−0.30</td>
                <td>−0.19</td>
                <td>−0.18</td>
                <td>0.63</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>SKE3</td>
                <td>−0.15</td>
                <td>−0.21</td>
                <td>−0.15</td>
                <td>0.03</td>
                <td>−0.19</td>
                <td>−0.26</td>
                <td>−0.22</td>
                <td>−0.15</td>
                <td>0.71</td>
                <td>0.72</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>SKE4</td>
                <td>−0.09</td>
                <td>−0.18</td>
                <td>−0.07</td>
                <td>0.04</td>
                <td>−0.22</td>
                <td>−0.28</td>
                <td>−0.28</td>
                <td>−0.25</td>
                <td>0.63</td>
                <td>0.69</td>
                <td>0.75</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>TET<sup>e</sup>1</td>
                <td>−0.44</td>
                <td>−0.42</td>
                <td>−0.50</td>
                <td>0.58</td>
                <td>−0.42</td>
                <td>−0.41</td>
                <td>−0.28</td>
                <td>−0.33</td>
                <td>0.24</td>
                <td>0.21</td>
                <td>0.24</td>
                <td>0.22</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>TET2</td>
                <td>−0.36</td>
                <td>−0.39</td>
                <td>−0.42</td>
                <td>0.33</td>
                <td>−0.43</td>
                <td>−0.45</td>
                <td>−0.39</td>
                <td>−0.43</td>
                <td>0.41</td>
                <td>0.34</td>
                <td>0.41</td>
                <td>0.45</td>
                <td>0.63</td>
                <td>1</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>TET3</td>
                <td>−0.39</td>
                <td>−0.34</td>
                <td>−0.41</td>
                <td>0.36</td>
                <td>−0.47</td>
                <td>−0.38</td>
                <td>−0.34</td>
                <td>−0.41</td>
                <td>0.38</td>
                <td>0.25</td>
                <td>0.30</td>
                <td>0.38</td>
                <td>0.66</td>
                <td>0.72</td>
                <td>1</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>TET4</td>
                <td>−0.22</td>
                <td>−0.22</td>
                <td>−0.29</td>
                <td>0.18</td>
                <td>−0.45</td>
                <td>−0.50</td>
                <td>−0.33</td>
                <td>−0.40</td>
                <td>0.54</td>
                <td>0.41</td>
                <td>0.48</td>
                <td>0.51</td>
                <td>0.39</td>
                <td>0.68</td>
                <td>0.62</td>
                <td>1</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table4fn1">
              <p><sup>a</sup>CON: confidence in effectiveness.</p>
            </fn>
            <fn id="table4fn2">
              <p><sup>b</sup>Not applicable.</p>
            </fn>
            <fn id="table4fn3">
              <p><sup>c</sup>ABE: anonymity benefits.</p>
            </fn>
            <fn id="table4fn4">
              <p><sup>d</sup>SKE: skepticism and perception of risk.</p>
            </fn>
            <fn id="table4fn5">
              <p><sup>e</sup>TET: technologization threat.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table5">
          <label>Table 5</label>
          <caption>
            <p>Descriptive statistics of the 16 Attitudes Towards Psychological Online Interventions items.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="90"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="60"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <col width="50"/>
            <thead>
              <tr valign="top">
                <td/>
                <td>CON<sup>a</sup>1</td>
                <td>CON2</td>
                <td>CON3</td>
                <td>CON4</td>
                <td>ABE<sup>b</sup>1</td>
                <td>ABE2</td>
                <td>ABE3</td>
                <td>ABE4</td>
                <td>SKE<sup>c</sup>1</td>
                <td>SKE2</td>
                <td>SKE3</td>
                <td>SKE4</td>
                <td>TET<sup>d</sup>1</td>
                <td>TET2</td>
                <td>TET3</td>
                <td>TET4</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Values, mean (SD)</td>
                <td>3.6 (1.0)</td>
                <td>3.4 (1.0)</td>
                <td>3.6 (1.0)</td>
                <td>3.7 (1.0)</td>
                <td>3.3 (1.0)</td>
                <td>3.2 (0.09)</td>
                <td>3.0 (1.0)</td>
                <td>3.2 (1.1)</td>
                <td>3.1 (1.2)</td>
                <td>3.3 (1.1)</td>
                <td>3.1 (1.1)</td>
                <td>3.2 (1.1)</td>
                <td>2.5 (1.0)</td>
                <td>2.7 (1.0)</td>
                <td>2.6 (1.0)</td>
                <td>2.9 (1.1)</td>
              </tr>
              <tr valign="top">
                <td>Skew</td>
                <td>−0.41</td>
                <td>−0.15</td>
                <td>−0.51</td>
                <td>−0.50</td>
                <td>−0.03</td>
                <td>0.04</td>
                <td>0.01</td>
                <td>−0.08</td>
                <td>−0.09</td>
                <td>−0.19</td>
                <td>−0.07</td>
                <td>−0.13</td>
                <td>0.26</td>
                <td>0.03</td>
                <td>0.18</td>
                <td>0.11</td>
              </tr>
              <tr valign="top">
                <td>Kurt</td>
                <td>0.07</td>
                <td>0.24</td>
                <td>0.34</td>
                <td>0.16</td>
                <td>−0.02</td>
                <td>0.09</td>
                <td>−0.12</td>
                <td>−0.14</td>
                <td>−0.50</td>
                <td>−0.34</td>
                <td>−0.18</td>
                <td>−0.33</td>
                <td>0.30</td>
                <td>0.16</td>
                <td>0.07</td>
                <td>−0.06</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table5fn1">
              <p><sup>a</sup>CON: confidence in effectiveness.</p>
            </fn>
            <fn id="table5fn2">
              <p><sup>b</sup>ABE: anonymity benefits.</p>
            </fn>
            <fn id="table5fn3">
              <p><sup>c</sup>SKE: skepticism and perception of risk.</p>
            </fn>
            <fn id="table5fn4">
              <p><sup>d</sup>TET: technologization threat.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Higher-order, 2-factor model depicting hierarchical relationship among indicators of 2 latent factors: positive and negative attitudes toward treatment loading on a global acceptability factor. ABE: anonymity benefits; CON: confidence in effectiveness; SKE: skepticism and perception of risk; TET: technologization threat. Note: threshold structure not shown.</p>
          </caption>
          <graphic xlink:href="mental_v10i1e43929_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Higher-order, 4-factor model depicting hierarchical relationship among indicators of 4 latent factors: confidence, anonymity benefits, skepticism, and technologization threat loading on a global acceptability factor. ABE: anonymity benefits; CON: confidence in effectiveness; SKE: skepticism and perception of risk; TET: technologization threat. Note: threshold structure not shown.</p>
          </caption>
          <graphic xlink:href="mental_v10i1e43929_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Ethics Approval</title>
        <p>This study was conducted in compliance with The Georgia State University institutional review board protocol #H18341 and preregistered with the Open Science Framework [<xref ref-type="bibr" rid="ref45">45</xref>].</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Sample Characteristics</title>
        <p>A total of 268 participants were enrolled in the study and completed the survey. Of these, 14 participants were excluded because they did not complete the APOI questionnaire, thus yielding a sample of 254 participants. Participant ratings suggested mild symptoms of anxiety (mean 8.35, SD 7.10) and stress (mean 11.96, SD 7.88) and normal levels of depressive symptoms (mean 9.00, SD 8.49) according to standard thresholds of the DASS-21 [<xref ref-type="bibr" rid="ref39">39</xref>].</p>
      </sec>
      <sec>
        <title>Construct Validity</title>
        <p>The 2 proposed models explored the construct of acceptability as a hierarchical, 2-factor model comprising “positive attitudes” and “negative attitudes” toward therapist-assisted iCBT, or as a hierarchical, 4-factor model comprising 4 distinct domains of attitudes toward therapist-assisted iCBT (confidence in effectiveness, anonymity benefits, skepticism and perception of risk, and technologization threat). See <xref ref-type="table" rid="table6">Table 6</xref> for a full description of the model’s fit indices.</p>
        <p>Neither model had a perfect absolute model fit according to the chi-square test (model 1: χ<sup>2</sup><sub>103</sub>=1579., <italic>P</italic>&#60;.001; model 2: χ<sup>2</sup><sub>101</sub>=595.3, <italic>P</italic>&#60;.001). There was variation in the absolute values of correlation residuals, as residuals frequently exceeded 0.10 in model 1 (mean 0.14, SD 0.01), contrary to recommendations for ordered categorical variables [<xref ref-type="bibr" rid="ref36">36</xref>]. Correlation residuals were largely below 0.10 in model 2 (mean 0.07, SD 0.01). Model 1 indicated poor fit according to CFI (0.65), TLI (0.59), SRMR (0.12), and RMSEA (0.24, 90% CI 0.23-0.25). Model 2 demonstrated better fit estimates with CFI (0.88), TLI (0.86), SRMR (0.08), and marginally improved RMSEA (0.14, 90% CI 0.13-0.15). As neither model 1 nor model 2 demonstrated adequate fit indices, an alternative bifactor model 3 (shown in <xref ref-type="table" rid="table6">Table 6</xref>) was examined because it retains theoretical similarity to the structure proposed by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>], and hierarchical models (ie, model 2) have more parameter constraints and are nested within less constrained bifactor models (ie, model 3) [<xref ref-type="bibr" rid="ref46">46</xref>-<xref ref-type="bibr" rid="ref48">48</xref>]. In model 3, the 4 factors (CON, ABE, SKE, and TET) were specified as orthogonal (instead of hierarchical) to the global factor of acceptability (<xref rid="figure3" ref-type="fig">Figure 3</xref>). Chi-square tests did not indicate an absolute model fit: χ<sup>2</sup><sub>82</sub>=248.7, <italic>P</italic>&#60;.001, although the chi-square:df ratio was 3.03, which is within the recommended range between 2 and 5 [<xref ref-type="bibr" rid="ref44">44</xref>]. Furthermore, model 3 indicated better estimates with CFI=0.96, TLI=0.94, SRMR=0.03, and RMSEA=0.09, 90% CI 0.08-0.10. Overall, model 3 demonstrated adequate to good fit according to accepted thresholds [<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref44">44</xref>] and the absolute values of correlation residuals did not exceed 0.10 (mean 0.03, SD 0.002). Other equivalent models were investigated (informed by statistically significant modification indices and theoretical rationale), but none demonstrated both structural fit and conceptual interpretability or parsimony (see <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref> for all tested confirmatory factor analysis models).</p>
        <p>As models 1, 2, and 3 were nested, comparisons were conducted to verify the statistically improved model fit by examining the change in the chi-square statistic. As the scaled chi-square value for WLSMV cannot be used for traditional chi-square difference testing, the DIFFTEST option in Mplus (version 8.4) was used [<xref ref-type="bibr" rid="ref49">49</xref>]. As shown in <xref ref-type="table" rid="table6">Table 6</xref>, comparisons indicated a significant chi-square change, Δχ<sup>2</sup><sub>2</sub>=327.7, <italic>P</italic>&#60;.001, suggesting that model 2 was significantly better than model 1. Similarly, there was a significant chi-square change, Δχ<sup>2</sup><sub>19</sub>=231.9, <italic>P</italic>&#60;.001, suggesting that model 3 was significantly better than model 2. Model 3 was the best fitting model and is described in more detail below (see <xref ref-type="table" rid="table7">Table 7</xref> for full factor loadings and <xref rid="figure4" ref-type="fig">Figure 4</xref> for the model with parameter estimates).</p>
        <p>When examining the standardized factor loadings of the bifactor model, the absolute value of loadings for the categorical indicators ranged from 0.52 to 0.87 on their original 4 factors. Consistent with the findings of Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>], all indicators significantly loaded onto their respective latent factors (CON, ABE, SKE, and TET), supporting the theory that these 4 domains are valid indicators of attitudes toward internet-delivered treatment. Furthermore, the 2 positively valenced latent factors (CON and ABE) significantly covaried as similar yet distinct factors (ψ=0.54; <italic>P</italic>&#60;.001) as did the 2 negatively valenced latent factors (SKE, TET; ψ=0.70; <italic>P</italic>&#60;.001).</p>
        <p>The relationship between the 16 ordinal indicators and the global acceptability factor was more complex, as the absolute value of the loadings ranged from 0.004 to 0.70. Although the factor loadings for both CON and ABE indicators were positively correlated with the global acceptability factor, only CON indicators demonstrated adequate strength (0.35-0.70), whereas loadings for ABE items ranged from 0.02 to 0.28, suggesting a relatively weak relationship with the global factor. One item of the ABE subscale (ABE3) “I would be more likely to tell my friends that I use a therapist-assisted iCBT program than that I visit a therapist” did not load significantly on the global factor (λ=0.016; <italic>P</italic>=.83). Furthermore, there was significant heterogeneity in the factor loadings for both the SKE and TET indicators on the global factor. Despite its conceptualization as “negative attitudes,” factor loadings of indicators of SKE ranged from 0.15 to 0.20 and were <italic>positively</italic> correlated with the global acceptability factor. Conversely, factor loadings of indicators of TET ranged from 0.39 to 0.64 and were negatively correlated with the global acceptability factor. One item of the TET subscale (TET4) “I do not understand therapeutic concepts as well with a therapist-assisted iCBT as I do with a live therapist” did not load significantly on the global factor (λ=0.004; <italic>P</italic>=.95).</p>
        <p>Overall, the results from the bifactor model structure of the APOI provide evidence that the 4 factors proposed by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>] exhibit an orthogonal relationship with the global factor of acceptability. As expected, positively valenced factors were positively related to one another, negatively valenced factors were positively related to one another, and each item was a significant indicator of the 4 distinct subscales when controlling for the common variance shared by the global factor. The bifactor model shows that most (but not all) of the 16 APOI items are significant indicators of the global factor, although all SKE items were related in the opposite direction.</p>
        <table-wrap position="float" id="table6">
          <label>Table 6</label>
          <caption>
            <p>Goodness-of-fit indexes of models tested in confirmatory factor analysis.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="110"/>
            <col width="120"/>
            <col width="70"/>
            <col width="70"/>
            <col width="70"/>
            <col width="70"/>
            <col width="160"/>
            <col width="140"/>
            <col width="70"/>
            <col width="120"/>
            <thead>
              <tr valign="top">
                <td>Model name</td>
                <td>Chi-square (<italic>df</italic>)</td>
                <td><italic>P</italic> value</td>
                <td>CFI<sup>a</sup></td>
                <td>TLI<sup>b</sup></td>
                <td>SRMR<sup>c</sup></td>
                <td>RMSEA<sup>d</sup> (95% CI)</td>
                <td colspan="3">Comparison</td>
              </tr>
              <tr valign="top">
                <td/>
                <td/>
                <td/>
                <td/>
                <td/>
                <td/>
                <td/>
                <td>ΔChi-square (<italic>df</italic>)</td>
                <td><italic>P</italic> value</td>
                <td>Note</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>2 factor</td>
                <td>1579.8 (103)</td>
                <td>&#60;.001</td>
                <td>0.65</td>
                <td>0.59</td>
                <td>0.12</td>
                <td>0.24 (0.23-0.25)</td>
                <td>—<sup>e</sup></td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td>4 factor<sup>f</sup></td>
                <td>595.3 (101)</td>
                <td>&#60;.001</td>
                <td>0.88</td>
                <td>0.86</td>
                <td>0.08</td>
                <td>0.14 (0.13-0.15)</td>
                <td>984.45 (2)</td>
                <td>&#60;.001</td>
                <td>Versus model 1</td>
              </tr>
              <tr valign="top">
                <td>Bifactor<sup>f</sup></td>
                <td>248.7 (82)</td>
                <td>&#60;.001</td>
                <td>0.96</td>
                <td>0.94</td>
                <td>0.03</td>
                <td>0.09 (0.08-0.10)</td>
                <td>346.57 (19)</td>
                <td>&#60;.001</td>
                <td>Versus model 2</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table6fn1">
              <p><sup>a</sup>CFI: comparative fit index.</p>
            </fn>
            <fn id="table6fn2">
              <p><sup>b</sup>TLI: Tucker-Lewis index.</p>
            </fn>
            <fn id="table6fn3">
              <p><sup>c</sup>SRMR: standardized root mean squared residual.</p>
            </fn>
            <fn id="table6fn4">
              <p><sup>d</sup>RMSEA: root mean square error of approximation.</p>
            </fn>
            <fn id="table6fn5">
              <p><sup>e</sup>Not available.</p>
            </fn>
            <fn id="table6fn6">
              <p><sup>f</sup>DIFFTEST command used for weighted least squares means and variance adjusted estimators to test differences in model fit.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <fig id="figure3" position="float">
          <label>Figure 3</label>
          <caption>
            <p>Bifactor model depicting orthogonal relationship among indicators of 4 latent factors: confidence, anonymity benefits, skepticism, and technologization threat loading alongside a global acceptability factor. ABE: anonymity benefits; CON: confidence in effectiveness; SKE: skepticism and perception of risk; TET: technologization threat. Note: threshold structure not shown.</p>
          </caption>
          <graphic xlink:href="mental_v10i1e43929_fig3.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <table-wrap position="float" id="table7">
          <label>Table 7</label>
          <caption>
            <p>Model 3 (bifactor) standardized factor loadings with SEs.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="30"/>
            <col width="540"/>
            <col width="0"/>
            <col width="260"/>
            <col width="0"/>
            <col width="140"/>
            <thead>
              <tr valign="top">
                <td colspan="4">Relation or variable</td>
                <td colspan="2">Estimate (SE)</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="7">
                  <bold>Loadings</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Confidence in effectiveness (CON) BY</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON1</td>
                <td colspan="2">0.66 (0.06)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON2</td>
                <td colspan="2">0.83 (0.04)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON3</td>
                <td colspan="2">0.72 (0.06)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON4</td>
                <td colspan="2">0.52 (0.07)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Anonymity benefits (ABE) BY</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE1</td>
                <td colspan="2">0.77 (0.03)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE2</td>
                <td colspan="2">0.83 (0.03)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE3</td>
                <td colspan="2">0.75 (0.03)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE4</td>
                <td colspan="2">0.75 (0.03)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Skepticism and perception of risk (SKE) BY</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE1</td>
                <td colspan="2">0.79 (0.02)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE2</td>
                <td colspan="2">0.75 (0.03)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE3</td>
                <td colspan="2">0.87 (0.02)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE4</td>
                <td colspan="2">0.81 (0.02)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Technologization threat (TET) BY</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET1</td>
                <td colspan="2">0.54 (0.06)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET2</td>
                <td colspan="2">0.81 (0.03)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET3</td>
                <td colspan="2">0.72 (0.04)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET4</td>
                <td colspan="2">0.86 (0.03)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Acceptability BY</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON1</td>
                <td colspan="2">0.51 (0.07)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON2</td>
                <td colspan="2">0.35 (0.08)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON3</td>
                <td colspan="2">0.54 (0.08)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>CON4</td>
                <td colspan="2">0.70 (0.07)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE1</td>
                <td colspan="2">0.28 (0.07)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE2</td>
                <td colspan="2">0.18 (0.08)</td>
                <td colspan="2">.01</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE3</td>
                <td colspan="2">0.02 (0.08)</td>
                <td colspan="2">.83</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>ABE4</td>
                <td colspan="2">0.22 (0.07)</td>
                <td colspan="2">.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE1</td>
                <td colspan="2">0.16 (0.06)</td>
                <td colspan="2">.01</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE2</td>
                <td colspan="2">0.20 (0.06)</td>
                <td colspan="2">.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE3</td>
                <td colspan="2">0.15 (0.06)</td>
                <td colspan="2">.02</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>SKE4</td>
                <td colspan="2">0.15 (0.06)</td>
                <td colspan="2">.008</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET1</td>
                <td colspan="2">−0.64 (0.05)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET2</td>
                <td colspan="2">−0.31 (0.07)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET3</td>
                <td colspan="2">−0.39 (0.07)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>TET4</td>
                <td colspan="2">&#60;.01 (0.08)</td>
                <td colspan="2">.95</td>
              </tr>
              <tr valign="top">
                <td colspan="7">
                  <bold>Factor covariances</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Confidence in effectiveness WITH</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Anonymity benefits</td>
                <td colspan="2">0.54 (0.06)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Skepticism and perception of risks</td>
                <td colspan="2">−0.30 (0.05)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Technologization threat</td>
                <td colspan="2">−0.38 (0.06)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Acceptability</td>
                <td colspan="2">0.00 (—<sup>a</sup>)</td>
                <td colspan="2">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Anonymity benefits WITH</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Skepticism and perception of risks</td>
                <td colspan="2">−0.41 (0.06)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Technologization threat</td>
                <td colspan="2">−0.61 (0.05)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Acceptability</td>
                <td colspan="2">0.00 (—)</td>
                <td colspan="2">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Skepticism and perception of risk WITH</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Technologization threat</td>
                <td colspan="2">0.70 (0.05)</td>
                <td colspan="2">&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Acceptability</td>
                <td colspan="2">0.00 (—)</td>
                <td colspan="2">—</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="6">
                  <bold>Technologization threat WITH</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Acceptability</td>
                <td colspan="2">0.00 (—)</td>
                <td colspan="2">—</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table7fn1">
              <p><sup>a</sup>Not available.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <fig id="figure4" position="float">
          <label>Figure 4</label>
          <caption>
            <p>Bifactor model depicting orthogonal relationship among indicators of 4 latent factors: confidence, anonymity benefits, skepticism, and technologization threat loading alongside a global acceptability factor. Standardized parameter estimates shown. ABE: anonymity benefits; CON: confidence in effectiveness; SKE: skepticism and perception of risk; TET: technologization threat. Note: threshold structure not shown.</p>
          </caption>
          <graphic xlink:href="mental_v10i1e43929_fig4.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Reliability</title>
        <p>The APOI demonstrated excellent internal consistency for the total scale (Cronbach α=.89) and retained good-to-excellent reliability across subscales (Cronbach α=.84 for ABE, .85 for TET, .87 for SKE, and .90 for CON). Across subscales, the corrected item-total correlations ranged from 0.59 to 0.83, with a mean adjusted correlation of 0.71 indicating good item discrimination within subscales. The corrected item‐total correlations for the APOI total scale ranged from 0.45 to 0.68, with a mean adjusted correlation of 0.55, indicating good item discrimination within the total scale.</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>This study evaluated the psychometric properties of the APOI questionnaire [<xref ref-type="bibr" rid="ref24">24</xref>], which is the most robust and widely used measure of <italic>acceptability</italic> for digital mental health interventions within a sample of Black Americans. The APOI demonstrated good-to-excellent internal consistency in the current sample, both as a total score and across subscales (Cronbach α=.84−.90), which is stronger than the internal consistency reported in the original publication (Cronbach α=.62−.77).</p>
        <p>However, the original hierarchical, 4-factor model proposed by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>] exhibited relatively poor goodness-of-fit indices. Instead, the APOI showed the strongest evidence for construct validity of a bifactor model in which each of the indicators loaded on a global factor of acceptability and the global factor of acceptability was orthogonally related to the 4 subscales. Although this unexpected finding is inconsistent with the hierarchical model proposed by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>], it is consistent with the literature showing that bifactor models fit better than their equivalent higher-order model in more than 90% of comparisons for mental abilities test batteries [<xref ref-type="bibr" rid="ref50">50</xref>] and can be particularly valuable in evaluating the plausibility of subscales [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]. The strong, positive correlations between positively valenced subscales (confidence in effectiveness and anonymity benefits) and negatively valenced subscales (skepticism and perception of risk and technologization threat), and the negative correlations across oppositely valenced subscales are compelling evidence that the subscales have meaningful discriminant validity and can be interpreted in their own right.</p>
        <p>The heterogeneity of findings regarding model fit may be explained by the nature of the coefficients of the factor loadings and overall structure. Modeling both positive and negatively valenced factors onto a unitary, higher-order construct (ie, acceptability) can prove difficult, especially when variance exists among indicators of lower-order constructs. The factor loadings between the 16 indicators and global acceptability factor varied substantially. Several indicators loading on the ABE, SKE, and TET subscales exhibited relatively weak or null relations with acceptability or were in the opposite direction than expected. Items loaded on the ABE subscale, in particular, may indicate both facilitators and barriers to engagement with digital interventions, given the user’s conflicting perceptions of digital privacy and confidentiality [<xref ref-type="bibr" rid="ref8">8</xref>]. Items that loaded on the SKE subscale were positively correlated with acceptability which is contrary to the conceptualization of this subscale as a construct reflecting negative attitudes, although this is interpreted with caution, given their weak correlations.</p>
        <p>Scholars have called for better conceptualizations of acceptability [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref23">23</xref>], which have the potential to produce even more parsimonious measures by exploring new factors or consolidating indicators to reduce conceptual overlap. In particular, there is a growing need for evidence of the dimensions of acceptability that are demonstrably correlated with uptake, engagement, and adherence to digital mental health interventions. As discussed in prior research, this apparent discrepancy in consumer attitudes and behaviors may, in fact, be a consequence of the heterogeneous nature and definition of acceptability toward digital mental health interventions [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]. A considerable amount of research uses a single item to assess acceptability and results from this study, and others [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref32">32</xref>], demonstrate that single-items measures are inadequate for the operationalization of this heterogeneous construct.</p>
        <p>Furthermore, these data suggest that within a Black American population, there is greater utility in interpreting the APOI subscales as attitudinal constructs distinct from a global acceptability factor. However, given that the higher-order model is nested within the bifactor model [<xref ref-type="bibr" rid="ref46">46</xref>-<xref ref-type="bibr" rid="ref48">48</xref>], these models are not necessarily at odds with one another. Ultimately, these results provide support for the underlying validity of the 4 factors proposed by the APOI but eschew traditional practices of prioritizing the calculation of a single acceptability score at the expense of adequately measuring each relevant dimension of acceptability and reporting them in tandem with the global score for contextualization.</p>
      </sec>
      <sec>
        <title>Strengths and Limitations</title>
        <p>This is the first study to investigate the psychometric properties of the APOI questionnaire among a racially minoritized population. This study is the first to provide evidence for the cross-cultural equivalence of APOI among Black Americans. This is a notable contribution to the literature, as the vast majority of randomized controlled trials examining the efficacy and acceptability of iCBT do not include (or do not report) racial minorities in their studies [<xref ref-type="bibr" rid="ref13">13</xref>], and existing measures of consumer attitudes toward digital mental health interventions [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref33">33</xref>] have predominantly been developed and examined for validation within White majority (and predominantly European) samples. Furthermore, by modifying the target treatment from “psychological online interventions” to “therapist-assisted iCBT,” this study provides preliminary evidence for the utility of the APOI for diverse digital interventions with varying degrees of specificity. Overall, the results suggest that the APOI is a robust measure.</p>
        <p>Despite the strengths of this study, there are some limitations that warrant attention. The study sample consisted of participants with minimal symptoms of depression, anxiety, or stress. This was distinct from the participants who reported moderate levels of depression in the study by Schröder et al [<xref ref-type="bibr" rid="ref24">24</xref>]. Future research needs to evaluate these measures among those with greater depression severity or other diagnoses. The participants in this study were predominantly young adult females. These demographic groups are more likely to use digital mental health interventions, and the relative impact of their positive and negative attitudes towards digital mental health intervention is likely to differ across diverse populations [<xref ref-type="bibr" rid="ref8">8</xref>]. Relatedly, measurement invariance was not formally assessed across different subgroups within the sample (eg, male vs female), because of significant imbalances in sample size, which minimized the power to detect potential differences between these groups. Finally, the convergent validity of the APOI with other measures of acceptability within a Black American sample could not be determined because no other relevant measures of acceptability existed at the time of data collection for this study.</p>
      </sec>
      <sec>
        <title>Future Directions</title>
        <p>Future research should modify the APOI to apply it to other digital mental health interventions (eg, virtual reality exposure therapies and massively open web-based interventions) and translate the measure into additional languages (eg, Spanish) to further examine cross-intervention and cross-cultural equivalency. Although the APOI demonstrated good internal consistency reliability within the present sample, test-retest reliability was not examined. Indeed, with the exception of the study by Clough et al [<xref ref-type="bibr" rid="ref29">29</xref>], there is a notable lack of investigation of the test-retest reliability of acceptability measures, which deserves further evaluation. Moreover, it would be compelling to investigate the criterion validity of the APOI to examine whether positive attitudes toward digital mental health interventions predict the willingness to use or actual use of digital mental health interventions among racially and ethnically minoritized participants. Consistent with the Theory of Planned Behavior [<xref ref-type="bibr" rid="ref53">53</xref>], which emphasizes the relationship among beliefs, attitudes, and behavioral intentions, positive attitudes toward acceptability would be expected to be the strongest predictor of behavioral intention, which in turn is the immediate determinant of actual treatment-seeking behavior. Investigations of the relationship between attitudes toward iCBT and the effectiveness of such interventions should be conducted, as those with more positive attitudes might derive greater clinical benefits. Finally, although studies examining the convergent validity of the APOI with related measures of acceptability toward digital mental health interventions have been recently conducted [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>], these studies did not expressly recruit participants from racially and ethnically minoritized communities, and their results are predominantly based on White or European samples. This is concerning, as racially and ethnically minoritized communities may be positioned to benefit the most from the treatment accessibility advantages afforded by digital mental health interventions [<xref ref-type="bibr" rid="ref54">54</xref>]. Understanding these communities’ attitudes toward these treatments is paramount.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>The APOI questionnaire is a valid and reliable measure of attitudes toward therapist-assisted iCBT among Black Americans. However, some of the indicators were only weakly associated with the global factor of acceptability, and a bifactor model demonstrated better goodness-of-fit than the hierarchical, 4-factor structure proposed by the original authors. This provides strong evidence that the APOI demonstrates multidimensionality and that there is greater utility in interpreting APOI subscales as attitudinal constructs distinct from a global acceptability factor. Indeed, attitudes of acceptability comprise both positive and negative attitudes toward the uptake of digital mental health interventions and must be evaluated in tandem to effectively understand the nuanced attitudes consumers may hold toward these interventions. This is the first study to examine the psychometric properties of any measure of consumer attitudes toward digital mental health interventions among Black participants. Demonstrating the reliability, validity, and cultural equivalency of existing measures of attitudes toward these interventions is needed to improve our understanding of the drivers of and barriers to using digital treatments among minoritized communities. For the full potential of digital mental health interventions to improve equitable access to treatment to be realized, more adequate representation of minoritized communities in research on these interventions must be achieved.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Materials depict fit indices for all examined confirmatory factor analyses. Mplus (version 8.4) syntax is provided for all analyses.</p>
        <media xlink:href="mental_v10i1e43929_app1.docx" xlink:title="DOCX File , 32 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">APOI</term>
          <def>
            <p>Attitudes Towards Psychological Online Interventions</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CFI</term>
          <def>
            <p>comparative fit index</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">DASS-21</term>
          <def>
            <p>Depression Anxiety Stress Scale-21 items</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">iCBT</term>
          <def>
            <p>internet-based cognitive behavioral therapy</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">RMSEA</term>
          <def>
            <p>root mean square error of approximation</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">SRMR</term>
          <def>
            <p>standardized root mean squared residual</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">TLI</term>
          <def>
            <p>Tucker-Lewis index</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">WLSMV</term>
          <def>
            <p>weighted least squares means and variance adjusted</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The authors would like to thank Lee Branum-Martin, PhD, for consultation on structural equation modeling and confirmatory factor analyses. The data in this study are a secondary analysis by Ellis and Anderson [<xref ref-type="bibr" rid="ref37">37</xref>]. This paper presents original secondary analyses of a previously published experimental survey study.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>DME devised the project, main conceptual ideas, and protocol outline and conducted all the statistical analyses; designed the figures and tables; and wrote the manuscript. Both DME and PLA contributed to the final version of this manuscript. PLA supervised the project.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Alegría</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Canino</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Ríos</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Vera</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Calderón</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Rusch</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Ortega</surname>
              <given-names>AN</given-names>
            </name>
          </person-group>
          <article-title>Inequalities in use of specialty mental health services among Latinos, African Americans, and non-Latino whites</article-title>
          <source>Psychiatr Serv</source>
          <year>2002</year>
          <month>12</month>
          <volume>53</volume>
          <issue>12</issue>
          <fpage>1547</fpage>
          <lpage>55</lpage>
          <pub-id pub-id-type="doi">10.1176/appi.ps.53.12.1547</pub-id>
          <pub-id pub-id-type="medline">12461214</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ayalon</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Alvidrez</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>The experience of Black consumers in the mental health system--identifying barriers to and facilitators of mental health treatment using the consumers' perspective</article-title>
          <source>Issues Ment Health Nurs</source>
          <year>2007</year>
          <month>12</month>
          <day>09</day>
          <volume>28</volume>
          <issue>12</issue>
          <fpage>1323</fpage>
          <lpage>40</lpage>
          <pub-id pub-id-type="doi">10.1080/01612840701651454</pub-id>
          <pub-id pub-id-type="medline">18058337</pub-id>
          <pub-id pub-id-type="pii">787700852</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gaston</surname>
              <given-names>GB</given-names>
            </name>
            <name name-style="western">
              <surname>Earl</surname>
              <given-names>TR</given-names>
            </name>
            <name name-style="western">
              <surname>Nisanci</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Glomb</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Perception of mental health services among Black Americans</article-title>
          <source>Social Work in Mental Health</source>
          <year>2016</year>
          <month>02</month>
          <day>16</day>
          <volume>14</volume>
          <issue>6</issue>
          <fpage>676</fpage>
          <lpage>95</lpage>
          <pub-id pub-id-type="doi">10.1080/15332985.2015.1137257</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Rozental</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Carlbring</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Internet-delivered psychological treatments: from innovation to implementation</article-title>
          <source>World Psychiatry</source>
          <year>2019</year>
          <month>02</month>
          <volume>18</volume>
          <issue>1</issue>
          <fpage>20</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/30600624"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/wps.20610</pub-id>
          <pub-id pub-id-type="medline">30600624</pub-id>
          <pub-id pub-id-type="pmcid">PMC6313242</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gerhards</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>de Graaf</surname>
              <given-names>L E</given-names>
            </name>
            <name name-style="western">
              <surname>Jacobs</surname>
              <given-names>LE</given-names>
            </name>
            <name name-style="western">
              <surname>Severens</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>Huibers</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Arntz</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Riper</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Widdershoven</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Metsemakers</surname>
              <given-names>JF</given-names>
            </name>
            <name name-style="western">
              <surname>Evers</surname>
              <given-names>SM</given-names>
            </name>
          </person-group>
          <article-title>Economic evaluation of online computerised cognitive-behavioural therapy without support for depression in primary care: randomised trial</article-title>
          <source>Br J Psychiatry</source>
          <year>2010</year>
          <month>04</month>
          <volume>196</volume>
          <issue>4</issue>
          <fpage>310</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1192/bjp.bp.109.065748</pub-id>
          <pub-id pub-id-type="medline">20357309</pub-id>
          <pub-id pub-id-type="pii">S0007125000252240</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hedman</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Ljótsson</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Rück</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Lindefors</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Cost-effectiveness of internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trial</article-title>
          <source>Behav Res Ther</source>
          <year>2011</year>
          <month>11</month>
          <volume>49</volume>
          <issue>11</issue>
          <fpage>729</fpage>
          <lpage>36</lpage>
          <pub-id pub-id-type="doi">10.1016/j.brat.2011.07.009</pub-id>
          <pub-id pub-id-type="medline">21851929</pub-id>
          <pub-id pub-id-type="pii">S0005-7967(11)00158-6</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Carolan</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>de Visser</surname>
              <given-names>RO</given-names>
            </name>
          </person-group>
          <article-title>Employees' perspectives on the facilitators and barriers to engaging with digital mental health interventions in the workplace: qualitative study</article-title>
          <source>JMIR Ment Health</source>
          <year>2018</year>
          <month>01</month>
          <day>19</day>
          <volume>5</volume>
          <issue>1</issue>
          <fpage>e8</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2018/1/e8/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mental.9146</pub-id>
          <pub-id pub-id-type="medline">29351900</pub-id>
          <pub-id pub-id-type="pii">v5i1e8</pub-id>
          <pub-id pub-id-type="pmcid">PMC5797290</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Borghouts</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Eikey</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Mark</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>De Leon</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Schueller</surname>
              <given-names>SM</given-names>
            </name>
            <name name-style="western">
              <surname>Schneider</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Stadnick</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Zheng</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Mukamel</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Sorkin</surname>
              <given-names>DH</given-names>
            </name>
          </person-group>
          <article-title>Barriers to and facilitators of user engagement with digital mental health interventions: systematic review</article-title>
          <source>J Med Internet Res</source>
          <year>2021</year>
          <month>03</month>
          <day>24</day>
          <volume>23</volume>
          <issue>3</issue>
          <fpage>e24387</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2021/3/e24387/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/24387</pub-id>
          <pub-id pub-id-type="medline">33759801</pub-id>
          <pub-id pub-id-type="pii">v23i3e24387</pub-id>
          <pub-id pub-id-type="pmcid">PMC8074985</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Himle</surname>
              <given-names>JA</given-names>
            </name>
            <name name-style="western">
              <surname>Weaver</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Xiang</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>Digital mental health interventions for depression</article-title>
          <source>Cognit Behavioral Pract</source>
          <year>2022</year>
          <month>02</month>
          <volume>29</volume>
          <issue>1</issue>
          <fpage>50</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1016/j.cbpra.2020.12.009</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Johansson</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Internet-based psychological treatments for depression</article-title>
          <source>Expert Rev Neurother</source>
          <year>2012</year>
          <month>07</month>
          <volume>12</volume>
          <issue>7</issue>
          <fpage>861</fpage>
          <lpage>9; quiz 870</lpage>
          <pub-id pub-id-type="doi">10.1586/ern.12.63</pub-id>
          <pub-id pub-id-type="medline">22853793</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Linardon</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Carlbring</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Messer</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fuller-Tyszkiewicz</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>The efficacy of app-supported smartphone interventions for mental health problems: a meta-analysis of randomized controlled trials</article-title>
          <source>World Psychiatry</source>
          <year>2019</year>
          <month>10</month>
          <day>09</day>
          <volume>18</volume>
          <issue>3</issue>
          <fpage>325</fpage>
          <lpage>36</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/31496095"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/wps.20673</pub-id>
          <pub-id pub-id-type="medline">31496095</pub-id>
          <pub-id pub-id-type="pmcid">PMC6732686</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bernstein</surname>
              <given-names>EE</given-names>
            </name>
            <name name-style="western">
              <surname>Weingarden</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Wolfe</surname>
              <given-names>EC</given-names>
            </name>
            <name name-style="western">
              <surname>Hall</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Snorrason</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Wilhelm</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Human support in app-based cognitive behavioral therapies for emotional disorders: scoping review</article-title>
          <source>J Med Internet Res</source>
          <year>2022</year>
          <month>04</month>
          <day>08</day>
          <volume>24</volume>
          <issue>4</issue>
          <fpage>e33307</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2022/4/e33307/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/33307</pub-id>
          <pub-id pub-id-type="medline">35394434</pub-id>
          <pub-id pub-id-type="pii">v24i4e33307</pub-id>
          <pub-id pub-id-type="pmcid">PMC9034419</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Basu</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Craske</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>English</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Computer therapy for the anxiety and depression disorders is effective, acceptable and practical health care: an updated meta-analysis</article-title>
          <source>J Anxiety Disord</source>
          <year>2018</year>
          <month>04</month>
          <volume>55</volume>
          <fpage>70</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0887-6185(17)30447-4"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2018.01.001</pub-id>
          <pub-id pub-id-type="medline">29422409</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(17)30447-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Barak</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hen</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Boniel-Nissim</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Shapira</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>A comprehensive review and a meta-analysis of the effectiveness of internet-based psychotherapeutic interventions</article-title>
          <source>J Technol Human Serv</source>
          <year>2008</year>
          <month>07</month>
          <day>03</day>
          <volume>26</volume>
          <issue>2-4</issue>
          <fpage>109</fpage>
          <lpage>60</lpage>
          <pub-id pub-id-type="doi">10.1080/15228830802094429</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Apolinário-Hagen</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Kemper</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Stürmer</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Public acceptability of e-mental health treatment services for psychological problems: a scoping review</article-title>
          <source>JMIR Ment Health</source>
          <year>2017</year>
          <month>04</month>
          <day>03</day>
          <volume>4</volume>
          <issue>2</issue>
          <fpage>e10</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2017/2/e10/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mental.6186</pub-id>
          <pub-id pub-id-type="medline">28373153</pub-id>
          <pub-id pub-id-type="pii">v4i2e10</pub-id>
          <pub-id pub-id-type="pmcid">PMC5394261</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Waller</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Gilbody</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Barriers to the uptake of computerized cognitive behavioural therapy: a systematic review of the quantitative and qualitative evidence</article-title>
          <source>Psychol Med</source>
          <year>2009</year>
          <month>05</month>
          <volume>39</volume>
          <issue>5</issue>
          <fpage>705</fpage>
          <lpage>12</lpage>
          <pub-id pub-id-type="doi">10.1017/S0033291708004224</pub-id>
          <pub-id pub-id-type="medline">18812006</pub-id>
          <pub-id pub-id-type="pii">S0033291708004224</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Casey</surname>
              <given-names>LM</given-names>
            </name>
            <name name-style="western">
              <surname>Joy</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Clough</surname>
              <given-names>BA</given-names>
            </name>
          </person-group>
          <article-title>The impact of information on attitudes toward e-mental health services</article-title>
          <source>Cyberpsychol Behav Soc Netw</source>
          <year>2013</year>
          <month>08</month>
          <volume>16</volume>
          <issue>8</issue>
          <fpage>593</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1089/cyber.2012.0515</pub-id>
          <pub-id pub-id-type="medline">23679567</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mitchell</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Gordon</surname>
              <given-names>PK</given-names>
            </name>
          </person-group>
          <article-title>Attitudes towards computerized CBT for depression amongst a student population</article-title>
          <source>Behav Cognit Psychother</source>
          <year>2007</year>
          <month>05</month>
          <day>14</day>
          <volume>35</volume>
          <issue>4</issue>
          <fpage>421</fpage>
          <lpage>30</lpage>
          <pub-id pub-id-type="doi">10.1017/s1352465807003700</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Travers</surname>
              <given-names>MF</given-names>
            </name>
            <name name-style="western">
              <surname>Benton</surname>
              <given-names>SA</given-names>
            </name>
          </person-group>
          <article-title>The acceptability of therapist-assisted, internet-delivered treatment for college students</article-title>
          <source>J College Student Psychother</source>
          <year>2014</year>
          <month>01</month>
          <day>14</day>
          <volume>28</volume>
          <issue>1</issue>
          <fpage>35</fpage>
          <lpage>46</lpage>
          <pub-id pub-id-type="doi">10.1080/87568225.2014.854676</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mohr</surname>
              <given-names>DC</given-names>
            </name>
            <name name-style="western">
              <surname>Siddique</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ho</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Duffecy</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Jin</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Fokuo</surname>
              <given-names>JK</given-names>
            </name>
          </person-group>
          <article-title>Interest in behavioral and psychological treatments delivered face-to-face, by telephone, and by internet</article-title>
          <source>Ann Behav Med</source>
          <year>2010</year>
          <month>08</month>
          <volume>40</volume>
          <issue>1</issue>
          <fpage>89</fpage>
          <lpage>98</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/20652466"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s12160-010-9203-7</pub-id>
          <pub-id pub-id-type="medline">20652466</pub-id>
          <pub-id pub-id-type="pmcid">PMC2914835</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Sharpe</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Hunt</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Acceptability of psychological treatment to Chinese- and Caucasian-Australians: internet treatment reduces barriers but face-to-face care is preferred</article-title>
          <source>Soc Psychiatry Psychiatr Epidemiol</source>
          <year>2015</year>
          <month>01</month>
          <volume>50</volume>
          <issue>1</issue>
          <fpage>77</fpage>
          <lpage>87</lpage>
          <pub-id pub-id-type="doi">10.1007/s00127-014-0921-1</pub-id>
          <pub-id pub-id-type="medline">24993290</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Molloy</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Ellis</surname>
              <given-names>DM</given-names>
            </name>
            <name name-style="western">
              <surname>Su</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Anderson</surname>
              <given-names>PL</given-names>
            </name>
          </person-group>
          <article-title>Improving acceptability and uptake behavior for internet-based cognitive-behavioral therapy</article-title>
          <source>Front Digit Health</source>
          <year>2021</year>
          <volume>3</volume>
          <fpage>653686</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/34713125"/>
          </comment>
          <pub-id pub-id-type="doi">10.3389/fdgth.2021.653686</pub-id>
          <pub-id pub-id-type="medline">34713125</pub-id>
          <pub-id pub-id-type="pmcid">PMC8521972</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ng</surname>
              <given-names>MM</given-names>
            </name>
            <name name-style="western">
              <surname>Firth</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Minen</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Torous</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>User engagement in mental health apps: a review of measurement, reporting, and validity</article-title>
          <source>Psychiatr Serv</source>
          <year>2019</year>
          <month>07</month>
          <day>01</day>
          <volume>70</volume>
          <issue>7</issue>
          <fpage>538</fpage>
          <lpage>44</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/30914003"/>
          </comment>
          <pub-id pub-id-type="doi">10.1176/appi.ps.201800519</pub-id>
          <pub-id pub-id-type="medline">30914003</pub-id>
          <pub-id pub-id-type="pmcid">PMC6839109</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schröder</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Sautier</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Kriston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Berger</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Meyer</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Späth</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Köther</surname>
              <given-names>U</given-names>
            </name>
            <name name-style="western">
              <surname>Nestoriuc</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>JP</given-names>
            </name>
            <name name-style="western">
              <surname>Moritz</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Development of a questionnaire measuring attitudes towards Psychological Online Interventions-the APOI</article-title>
          <source>J Affect Disord</source>
          <year>2015</year>
          <month>11</month>
          <day>15</day>
          <volume>187</volume>
          <fpage>136</fpage>
          <lpage>41</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2015.08.044</pub-id>
          <pub-id pub-id-type="medline">26331687</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(15)30148-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Devilly</surname>
              <given-names>GJ</given-names>
            </name>
            <name name-style="western">
              <surname>Borkovec</surname>
              <given-names>TD</given-names>
            </name>
          </person-group>
          <article-title>Psychometric properties of the credibility/expectancy questionnaire</article-title>
          <source>J Behav Ther Exp Psychiatry</source>
          <year>2000</year>
          <month>06</month>
          <volume>31</volume>
          <issue>2</issue>
          <fpage>73</fpage>
          <lpage>86</lpage>
          <pub-id pub-id-type="doi">10.1016/s0005-7916(00)00012-4</pub-id>
          <pub-id pub-id-type="medline">11132119</pub-id>
          <pub-id pub-id-type="pii">S0005791600000124</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Handley</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Perkins</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Kay-Lambkin</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Lewin</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Kelly</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Familiarity with and intentions to use internet-delivered mental health treatments among older rural adults</article-title>
          <source>Aging Ment Health</source>
          <year>2015</year>
          <volume>19</volume>
          <issue>11</issue>
          <fpage>989</fpage>
          <lpage>96</lpage>
          <pub-id pub-id-type="doi">10.1080/13607863.2014.981744</pub-id>
          <pub-id pub-id-type="medline">25420968</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>BM</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Spence</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Kemp</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>The acceptability of internet-based treatment and characteristics of an adult sample with obsessive compulsive disorder: an internet survey</article-title>
          <source>PLoS One</source>
          <year>2011</year>
          <volume>6</volume>
          <issue>6</issue>
          <fpage>e20548</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0020548"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0020548</pub-id>
          <pub-id pub-id-type="medline">21673987</pub-id>
          <pub-id pub-id-type="pii">PONE-D-11-03091</pub-id>
          <pub-id pub-id-type="pmcid">PMC3108613</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Apolinário-Hagen</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Vehreschild</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Alkoudmani</surname>
              <given-names>RM</given-names>
            </name>
          </person-group>
          <article-title>Current views and perspectives on e-mental health: an exploratory survey study for understanding public attitudes toward internet-based psychotherapy in Germany</article-title>
          <source>JMIR Ment Health</source>
          <year>2017</year>
          <month>02</month>
          <day>23</day>
          <volume>4</volume>
          <issue>1</issue>
          <fpage>e8</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2017/1/e8/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mental.6375</pub-id>
          <pub-id pub-id-type="medline">28232298</pub-id>
          <pub-id pub-id-type="pii">v4i1e8</pub-id>
          <pub-id pub-id-type="pmcid">PMC5378055</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Clough</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Eigeland</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Madden</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Rowland</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Casey</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Development of the eTAP: a brief measure of attitudes and process in e-interventions for mental health</article-title>
          <source>Internet Interv</source>
          <year>2019</year>
          <month>12</month>
          <volume>18</volume>
          <fpage>100256</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(18)30061-7"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2019.100256</pub-id>
          <pub-id pub-id-type="medline">31890610</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(18)30061-7</pub-id>
          <pub-id pub-id-type="pmcid">PMC6926169</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gómez Penedo</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Berger</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Grosse Holtforth</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Krieger</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Schröder</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hohagen</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Meyer</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Moritz</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>JP</given-names>
            </name>
          </person-group>
          <article-title>The Working Alliance Inventory for guided Internet interventions (WAI-I)</article-title>
          <source>J Clin Psychol</source>
          <year>2020</year>
          <month>06</month>
          <volume>76</volume>
          <issue>6</issue>
          <fpage>973</fpage>
          <lpage>86</lpage>
          <pub-id pub-id-type="doi">10.1002/jclp.22823</pub-id>
          <pub-id pub-id-type="medline">31240727</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Miloff</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Carlbring</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Hamilton</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Reuterskiöld</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Lindner</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Measuring alliance toward embodied virtual therapists in the era of automated treatments with the Virtual Therapist Alliance Scale (VTAS): development and psychometric evaluation</article-title>
          <source>J Med Internet Res</source>
          <year>2020</year>
          <month>03</month>
          <day>24</day>
          <volume>22</volume>
          <issue>3</issue>
          <fpage>e16660</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2020/3/e16660/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/16660</pub-id>
          <pub-id pub-id-type="medline">32207690</pub-id>
          <pub-id pub-id-type="pii">v22i3e16660</pub-id>
          <pub-id pub-id-type="pmcid">PMC7139418</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Teles</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Ferreira</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Paúl</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Assessing attitudes towards online psychoeducational interventions: psychometric properties of a Brief Attitudes Scale</article-title>
          <source>Health Soc Care Community</source>
          <year>2021</year>
          <month>09</month>
          <volume>29</volume>
          <issue>5</issue>
          <fpage>e1</fpage>
          <lpage>10</lpage>
          <pub-id pub-id-type="doi">10.1111/hsc.13227</pub-id>
          <pub-id pub-id-type="medline">33170537</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Miragall</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Baños</surname>
              <given-names>RM</given-names>
            </name>
            <name name-style="western">
              <surname>Cebolla</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Botella</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Working alliance inventory applied to virtual and augmented reality (WAI-VAR): psychometrics and therapeutic outcomes</article-title>
          <source>Front Psychol</source>
          <year>2015</year>
          <month>10</month>
          <day>08</day>
          <volume>6</volume>
          <fpage>1531</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/26500589"/>
          </comment>
          <pub-id pub-id-type="doi">10.3389/fpsyg.2015.01531</pub-id>
          <pub-id pub-id-type="medline">26500589</pub-id>
          <pub-id pub-id-type="pmcid">PMC4597032</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Horvath</surname>
              <given-names>AO</given-names>
            </name>
            <name name-style="western">
              <surname>Bedi</surname>
              <given-names>RP</given-names>
            </name>
          </person-group>
          <article-title>The alliance</article-title>
          <source>Psychotherapy Relationships That Work: Therapist Contributions and Responsiveness to Patients</source>
          <year>2002</year>
          <publisher-loc>Oxford, United Kingdom</publisher-loc>
          <publisher-name>Oxford University Press</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McDonald</surname>
              <given-names>RP</given-names>
            </name>
            <name name-style="western">
              <surname>Ho</surname>
              <given-names>MR</given-names>
            </name>
          </person-group>
          <article-title>Principles and practice in reporting structural equation analyses</article-title>
          <source>Psychol Method</source>
          <year>2002</year>
          <month>03</month>
          <volume>7</volume>
          <issue>1</issue>
          <fpage>64</fpage>
          <lpage>82</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://core.ac.uk/reader/22864817?utm_source=linkout"/>
          </comment>
          <pub-id pub-id-type="doi">10.1037/1082-989x.7.1.64</pub-id>
          <pub-id pub-id-type="medline">11928891</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kline</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <source>Principles and Practice of Structural Equation Modeling</source>
          <year>2015</year>
          <publisher-loc>New York City, NY</publisher-loc>
          <publisher-name>Guilford Publications</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ellis</surname>
              <given-names>DM</given-names>
            </name>
            <name name-style="western">
              <surname>Anderson</surname>
              <given-names>PL</given-names>
            </name>
          </person-group>
          <article-title>Improving the acceptability of internet-based cognitive-behavioral therapy among Black Americans</article-title>
          <source>Technol Mind Behav</source>
          <year>2021</year>
          <month>10</month>
          <day>18</day>
          <volume>2</volume>
          <issue>3</issue>
          <pub-id pub-id-type="doi">10.1037/tmb0000044</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Magaard</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>Seeralan</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Schulz</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Brütt</surname>
              <given-names>AL</given-names>
            </name>
          </person-group>
          <article-title>Factors associated with help-seeking behaviour among individuals with major depression: a systematic review</article-title>
          <source>PLoS One</source>
          <year>2017</year>
          <volume>12</volume>
          <issue>5</issue>
          <fpage>e0176730</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0176730"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0176730</pub-id>
          <pub-id pub-id-type="medline">28493904</pub-id>
          <pub-id pub-id-type="pii">PONE-D-16-46536</pub-id>
          <pub-id pub-id-type="pmcid">PMC5426609</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lovibond</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Lovibond</surname>
              <given-names>P</given-names>
            </name>
            <collab>Psychology Foundation of Australia</collab>
          </person-group>
          <source>Manual for the Depression Anxiety Stress Scales</source>
          <year>1995</year>
          <publisher-loc>Sydney, N.S.W</publisher-loc>
          <publisher-name>Psychology Foundation of Australia</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lovibond</surname>
              <given-names>PF</given-names>
            </name>
            <name name-style="western">
              <surname>Lovibond</surname>
              <given-names>SH</given-names>
            </name>
          </person-group>
          <article-title>The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories</article-title>
          <source>Behav Res Ther</source>
          <year>1995</year>
          <month>03</month>
          <volume>33</volume>
          <issue>3</issue>
          <fpage>335</fpage>
          <lpage>43</lpage>
          <pub-id pub-id-type="doi">10.1016/0005-7967(94)00075-u</pub-id>
          <pub-id pub-id-type="medline">7726811</pub-id>
          <pub-id pub-id-type="pii">0005-7967(94)00075-U</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Norton</surname>
              <given-names>PJ</given-names>
            </name>
          </person-group>
          <article-title>Depression Anxiety and Stress Scales (DASS-21): psychometric analysis across four racial groups</article-title>
          <source>Anxiety Stress Coping</source>
          <year>2007</year>
          <month>09</month>
          <volume>20</volume>
          <issue>3</issue>
          <fpage>253</fpage>
          <lpage>65</lpage>
          <pub-id pub-id-type="doi">10.1080/10615800701309279</pub-id>
          <pub-id pub-id-type="medline">17999228</pub-id>
          <pub-id pub-id-type="pii">781200904</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Fan</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Thompson</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Effects of sample size, estimation methods, and model specification on structural equation modeling fit indexes</article-title>
          <source>Structural Equat Model Multidisciplinary J</source>
          <year>1999</year>
          <month>01</month>
          <volume>6</volume>
          <issue>1</issue>
          <fpage>56</fpage>
          <lpage>83</lpage>
          <pub-id pub-id-type="doi">10.1080/10705519909540119</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hu</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Bentler</surname>
              <given-names>PM</given-names>
            </name>
          </person-group>
          <article-title>Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives</article-title>
          <source>Structural Equat Model Multidisciplinary J</source>
          <year>1999</year>
          <month>01</month>
          <volume>6</volume>
          <issue>1</issue>
          <fpage>1</fpage>
          <lpage>55</lpage>
          <pub-id pub-id-type="doi">10.1080/10705519909540118</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Marsh</surname>
              <given-names>HW</given-names>
            </name>
            <name name-style="western">
              <surname>Hocevar</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Application of confirmatory factor analysis to the study of self-concept: first- and higher order factor models and their invariance across groups</article-title>
          <source>Psychol Bull</source>
          <year>1985</year>
          <month>05</month>
          <volume>97</volume>
          <issue>3</issue>
          <fpage>562</fpage>
          <lpage>82</lpage>
          <pub-id pub-id-type="doi">10.1037/0033-2909.97.3.562</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ellis</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Anderson</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Cross-cultural validation of the attitudes towards psychological online interventions questionnaire among Black Americans</article-title>
          <source>OSF Registries</source>
          <year>2022</year>
          <access-date>2022-02-16</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://osf.io/y3r2p">https://osf.io/y3r2p</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Markon</surname>
              <given-names>KE</given-names>
            </name>
          </person-group>
          <article-title>Bifactor and hierarchical models: specification, inference, and interpretation</article-title>
          <source>Annu Rev Clin Psychol</source>
          <year>2019</year>
          <month>05</month>
          <day>07</day>
          <volume>15</volume>
          <issue>1</issue>
          <fpage>51</fpage>
          <lpage>69</lpage>
          <pub-id pub-id-type="doi">10.1146/annurev-clinpsy-050718-095522</pub-id>
          <pub-id pub-id-type="medline">30649927</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rijmen</surname>
              <given-names>F</given-names>
            </name>
          </person-group>
          <article-title>Formal relations and an empirical comparison among the bi-factor, the Testlet, and a second-order multidimensional IRT model</article-title>
          <source>J Educ Measurement</source>
          <year>2010</year>
          <volume>47</volume>
          <issue>3</issue>
          <fpage>361</fpage>
          <lpage>72</lpage>
          <pub-id pub-id-type="doi">10.1111/j.1745-3984.2010.00118.x</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Yung</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Thissen</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>McLeod</surname>
              <given-names>LD</given-names>
            </name>
          </person-group>
          <article-title>On the relationship between the higher-order factor model and the hierarchical factor model</article-title>
          <source>Psychometrika</source>
          <year>1999</year>
          <month>6</month>
          <volume>64</volume>
          <issue>2</issue>
          <fpage>113</fpage>
          <lpage>28</lpage>
          <pub-id pub-id-type="doi">10.1007/bf02294531</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Satorra</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Bentler</surname>
              <given-names>PM</given-names>
            </name>
          </person-group>
          <article-title>Ensuring positiveness of the scaled difference chi-square test statistic</article-title>
          <source>Psychometrika</source>
          <year>2010</year>
          <month>06</month>
          <day>20</day>
          <volume>75</volume>
          <issue>2</issue>
          <fpage>243</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/20640194"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s11336-009-9135-y</pub-id>
          <pub-id pub-id-type="medline">20640194</pub-id>
          <pub-id pub-id-type="pmcid">PMC2905175</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Cucina</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Byle</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>The bifactor model fits better than the higher-order model in more than 90% of comparisons for mental abilities test batteries</article-title>
          <source>J Intell</source>
          <year>2017</year>
          <month>07</month>
          <day>11</day>
          <volume>5</volume>
          <issue>3</issue>
          <fpage>27</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=jintelligence5030027"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/jintelligence5030027</pub-id>
          <pub-id pub-id-type="medline">31162418</pub-id>
          <pub-id pub-id-type="pii">jintelligence5030027</pub-id>
          <pub-id pub-id-type="pmcid">PMC6526460</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Reise</surname>
              <given-names>SP</given-names>
            </name>
            <name name-style="western">
              <surname>Moore</surname>
              <given-names>TM</given-names>
            </name>
            <name name-style="western">
              <surname>Haviland</surname>
              <given-names>MG</given-names>
            </name>
          </person-group>
          <article-title>Bifactor models and rotations: exploring the extent to which multidimensional data yield univocal scale scores</article-title>
          <source>J Pers Assess</source>
          <year>2010</year>
          <month>11</month>
          <volume>92</volume>
          <issue>6</issue>
          <fpage>544</fpage>
          <lpage>59</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/20954056"/>
          </comment>
          <pub-id pub-id-type="doi">10.1080/00223891.2010.496477</pub-id>
          <pub-id pub-id-type="medline">20954056</pub-id>
          <pub-id pub-id-type="pii">928143119</pub-id>
          <pub-id pub-id-type="pmcid">PMC2981404</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Reise</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Bonifay</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Haviland</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Bifactor modelling and the evaluation of scale scores</article-title>
          <source>The Wiley Handbook of Psychometric Testing, 2 Volume Set A Multidisciplinary Reference on Survey, Scale and Test Development · Volume 1</source>
          <year>2018</year>
          <publisher-loc>Hoboken, New Jersey</publisher-loc>
          <publisher-name>Wiley</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ajzen</surname>
              <given-names>I</given-names>
            </name>
          </person-group>
          <article-title>The theory of planned behavior</article-title>
          <source>Organizational Behav Human Decis Process</source>
          <year>1991</year>
          <month>12</month>
          <volume>50</volume>
          <issue>2</issue>
          <fpage>179</fpage>
          <lpage>211</lpage>
          <pub-id pub-id-type="doi">10.1016/0749-5978(91)90020-T</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref54">
        <label>54</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schueller</surname>
              <given-names>SM</given-names>
            </name>
            <name name-style="western">
              <surname>Hunter</surname>
              <given-names>JF</given-names>
            </name>
            <name name-style="western">
              <surname>Figueroa</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Aguilera</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Use of digital mental health for marginalized and underserved populations</article-title>
          <source>Curr Treat Options Psych</source>
          <year>2019</year>
          <month>7</month>
          <day>5</day>
          <volume>6</volume>
          <issue>3</issue>
          <fpage>243</fpage>
          <lpage>55</lpage>
          <pub-id pub-id-type="doi">10.1007/s40501-019-00181-z</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
