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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMH</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Ment Health</journal-id>
      <journal-title>JMIR Mental Health</journal-title>
      <issn pub-type="epub">2368-7959</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v9i2e31018</article-id>
      <article-id pub-id-type="pmid">35133281</article-id>
      <article-id pub-id-type="doi">10.2196/31018</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Web-Based Interventions to Help Australian Adults Address Depression, Anxiety, Suicidal Ideation, and General Mental Well-being: Scoping Review</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Torous</surname>
            <given-names>John</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Haskelberg</surname>
            <given-names>Hila</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Kessler</surname>
            <given-names>Ronald</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author">
          <name name-style="western">
            <surname>Skaczkowski</surname>
            <given-names>Gemma</given-names>
          </name>
          <degrees>BHSc (Hons), PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0715-3563</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>van der Kruk</surname>
            <given-names>Shannen</given-names>
          </name>
          <degrees>BSc, MSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5132-668X</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Loxton</surname>
            <given-names>Sophie</given-names>
          </name>
          <degrees>BPsych (Hons)</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-2358-6249</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Hughes-Barton</surname>
            <given-names>Donna</given-names>
          </name>
          <degrees>BSc, MPsych, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4764-7528</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Howell</surname>
            <given-names>Cate</given-names>
          </name>
          <degrees>BMBS, BAppSc, Dip Clin Hypnosis, MHSM, PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9526-5313</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Turnbull</surname>
            <given-names>Deborah</given-names>
          </name>
          <degrees>BA (Hons), MPsych, PhD</degrees>
          <xref rid="aff4" ref-type="aff">4</xref>
          <xref rid="aff5" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7116-7073</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Jensen</surname>
            <given-names>Neil</given-names>
          </name>
          <degrees>MBBS</degrees>
          <xref rid="aff5" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8068-6943</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author">
          <name name-style="western">
            <surname>Smout</surname>
            <given-names>Matthew</given-names>
          </name>
          <degrees>BSc (Hons), MPsych, PhD</degrees>
          <xref rid="aff6" ref-type="aff">6</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6952-6014</ext-link>
        </contrib>
        <contrib id="contrib9" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Gunn</surname>
            <given-names>Kate</given-names>
          </name>
          <degrees>BPsych (Hons), MPsych, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Rural Health, Allied Health and Human Performance</institution>
            <institution>University of South Australia</institution>
            <addr-line>North Terrace</addr-line>
            <addr-line>Adelaide, 5001</addr-line>
            <country>Australia</country>
            <phone>61 417852537</phone>
            <email>kate.gunn@unisa.edu.au</email>
          </address>
          <xref rid="aff5" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0837-6814</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Rural Health, Allied Health and Human Performance</institution>
        <institution>University of South Australia</institution>
        <addr-line>Adelaide</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Australian Medical Placements Health Education and Training</institution>
        <addr-line>Adelaide</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Torrens University</institution>
        <addr-line>Adelaide</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>School of Psychology</institution>
        <institution>The University of Adelaide</institution>
        <addr-line>Adelaide</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff5">
        <label>5</label>
        <institution>Freemasons Centre for Male Health and Wellbeing</institution>
        <addr-line>Adelaide</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff6">
        <label>6</label>
        <institution>Justice and Society</institution>
        <institution>University of South Australia</institution>
        <addr-line>Adelaide</addr-line>
        <country>Australia</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Kate Gunn <email>kate.gunn@unisa.edu.au</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>2</month>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>8</day>
        <month>2</month>
        <year>2022</year>
      </pub-date>
      <volume>9</volume>
      <issue>2</issue>
      <elocation-id>e31018</elocation-id>
      <history>
        <date date-type="received">
          <day>7</day>
          <month>6</month>
          <year>2021</year>
        </date>
        <date date-type="rev-request">
          <day>17</day>
          <month>7</month>
          <year>2021</year>
        </date>
        <date date-type="rev-recd">
          <day>23</day>
          <month>7</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>12</day>
          <month>8</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Gemma Skaczkowski, Shannen van der Kruk, Sophie Loxton, Donna Hughes-Barton, Cate Howell, Deborah Turnbull, Neil Jensen, Matthew Smout, Kate Gunn. Originally published in JMIR Mental Health (https://mental.jmir.org), 08.02.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Mental Health, is properly cited. The complete bibliographic information, a link to the original publication on https://mental.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://mental.jmir.org/2022/2/e31018" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>A large number of Australians experience mental health challenges at some point in their lives. However, in many parts of Australia, the wait times to see general practitioners and mental health professionals can be lengthy. With increasing internet use across Australia, web-based interventions may help increase access to timely mental health care. As a result, this is an area of increasing research interest, and the number of publicly available web-based interventions is growing. However, it can be confusing for clinicians and consumers to know the resources that are evidence-based and best meet their needs.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aims to scope out the range of web-based mental health interventions that address depression, anxiety, suicidal ideation, or general mental well-being and are freely available to Australian adults, along with their impact, acceptability, therapeutic approach, and key features.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for scoping reviews (PRISMA-ScR [PRISMA extension for Scoping Reviews]) guided the review process. Keywords for the search were depression, anxiety, suicide, and well-being. The search was conducted using Google as well as the key intervention databases Beacon, Head to Health, and e-Mental Health in Practice. Interventions were deemed eligible if they targeted depression, anxiety, suicidal ideation, or general mental well-being (eg, resilience) in adults; and were web-based, written in English, interactive, free, and publicly available. They also had to be guided by an evidence-based therapeutic approach.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Overall, 52 eligible programs were identified, of which 9 (17%) addressed depression, 15 (29%) addressed anxiety, 13 (25%) addressed general mental well-being, and 13 (25%) addressed multiple issues. Only 4% (2/52) addressed distress in the form of suicidal ideation. The most common therapeutic approach was cognitive behavioral therapy. Half of the programs guided users through exercises in a set sequence, and most programs enabled users to log in and complete the activities on their own without professional support. Just over half of the programs had been evaluated for their effectiveness in reducing symptoms, and 11% (6/52) were being evaluated at the time of writing. Program evaluation scores ranged from 44% to 100%, with a total average score of 85%.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>There are numerous web-based programs for depression, anxiety, suicidal ideation, and general well-being, which are freely and publicly available in Australia. However, identified gaps include a lack of available web-based interventions for culturally and linguistically diverse populations and programs that use newer therapeutic approaches such as acceptance and commitment therapy and dialectical behavior therapy. Despite most programs included in this review being of good quality, clinicians and consumers should pay careful attention when selecting which program to recommend and use, as variations in the levels of acceptability and impact of publicly available programs do exist.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>web-based interventions</kwd>
        <kwd>depression</kwd>
        <kwd>anxiety</kwd>
        <kwd>suicide</kwd>
        <kwd>well-being</kwd>
        <kwd>mental health</kwd>
        <kwd>technology</kwd>
        <kwd>access to health care</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>Approximately half of the Australian population experiences a common mental disorder (eg, anxiety and depression) at some point in their lives [<xref ref-type="bibr" rid="ref1">1</xref>]. Mental and substance use disorders are the fourth highest contributor to total disease burden after cancer, cardiovascular disease, and musculoskeletal conditions [<xref ref-type="bibr" rid="ref2">2</xref>], whereas suicide is the leading cause of death among young people aged between 15 and 44 years and the fourth leading cause of death in those aged between 45 and 64 years [<xref ref-type="bibr" rid="ref2">2</xref>]. Despite these alarming statistics, only one-third of people experiencing mental illness will access support services [<xref ref-type="bibr" rid="ref3">3</xref>]. The reasons for this may be structural (eg, availability of suitable services), knowledge-related (eg, limited awareness of the benefits of accessing mental health services), or attitudinal (eg, stigma and stoicism).</p>
        <p>When people do seek help for mental health issues, 71% will contact their general practitioner (GP) at the first instance [<xref ref-type="bibr" rid="ref3">3</xref>]. GPs play a crucial role in suicide prevention; approximately 45% of people who die by suicide have had contact with primary care in the preceding month and 77% in the preceding year [<xref ref-type="bibr" rid="ref4">4</xref>]. However, GPs report the lack of tools needed to administer psychological care, including a lack of time, resources, and confidence [<xref ref-type="bibr" rid="ref5">5</xref>]. Although GPs and their patients increasingly value psychological support, a shortage of professionals and time on wait lists, averaging between 2 and 6 months, is both frustrating and distressing for GPs and their patients.</p>
        <p>There is a pressing need to bridge the gap between primary health and mental health care, particularly for Australians facing greater difficulties in accessing mental health care and who are at particular risk of suicide, such as those in rural areas. Fortunately, Australians are increasingly willing to use the internet to search for health-related information [<xref ref-type="bibr" rid="ref6">6</xref>], with at least 86% of Australian households now having access to the internet [<xref ref-type="bibr" rid="ref7">7</xref>]. Therefore, web-based resources and interventions may supplement face-to-face services, providing support to people as they wait for appointments [<xref ref-type="bibr" rid="ref8">8</xref>] and new avenues to reach those who face structural or attitudinal barriers to accessing face-to-face mental health services [<xref ref-type="bibr" rid="ref9">9</xref>]. Web-based resources have the advantage of enabling consumers’ anonymity and access at any time of the day or night, from the privacy and convenience of their own homes [<xref ref-type="bibr" rid="ref8">8</xref>].</p>
        <p>Across the globe, web-based interventions have been shown to effectively reduce the severity of symptoms of depression [<xref ref-type="bibr" rid="ref10">10</xref>], anxiety [<xref ref-type="bibr" rid="ref11">11</xref>], and social anxiety [<xref ref-type="bibr" rid="ref12">12</xref>] and increase mental health literacy [<xref ref-type="bibr" rid="ref13">13</xref>] and the ability to recognize, accept, deal with, and help prevent mental health issues [<xref ref-type="bibr" rid="ref14">14</xref>]. The quality of this evidence is high, with a number of randomized controlled trials (RCTs; eg, the studies by McDermott et al [<xref ref-type="bibr" rid="ref10">10</xref>], Powell et al [<xref ref-type="bibr" rid="ref12">12</xref>], and Kiropoulos et al [<xref ref-type="bibr" rid="ref13">13</xref>]) and systematic reviews (eg, the studies by Renton et al [<xref ref-type="bibr" rid="ref15">15</xref>] and Ashford et al [<xref ref-type="bibr" rid="ref16">16</xref>]) illustrating their value. Participation has also been associated with decreases in personal stigmatizing attitudes toward depression in the mainstream population [<xref ref-type="bibr" rid="ref17">17</xref>] and among immigrants [<xref ref-type="bibr" rid="ref13">13</xref>], as well as decreases in stigmatizing attitudes toward suicide [<xref ref-type="bibr" rid="ref18">18</xref>] and help seeking [<xref ref-type="bibr" rid="ref19">19</xref>]. Importantly, web-based interventions have been identified as acceptable in difficult-to-reach populations such as farmers [<xref ref-type="bibr" rid="ref20">20</xref>], young people [<xref ref-type="bibr" rid="ref21">21</xref>], and culturally and linguistically diverse groups [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>]. They can be successfully integrated into routine primary care [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>], and many Australian GPs support the notion of aiding their patients’ mental well-being through these resources [<xref ref-type="bibr" rid="ref26">26</xref>]. In addition, web-based interventions have been found to be cost-effective for development and delivery; many are offered for free to consumers [<xref ref-type="bibr" rid="ref8">8</xref>]. However, with the plethora of interventions emerging on the internet [<xref ref-type="bibr" rid="ref27">27</xref>], there is a need for reliable and clear recommendations to help clinicians and consumers select web-based interventions that are based on evidence-based therapeutic approaches and meet their needs. The e-Mental Health in Practice (eMHPrac) project, funded by the Australian Government, has a range of resources to help Australian health practitioners find digital mental health programs for use with their patients [<xref ref-type="bibr" rid="ref28">28</xref>]. This provides an excellent quick reference guide for clinicians. However, it does not outline the types of therapeutic approaches and tools used or indicate whether resources are evidence-based.</p>
        <p>A total of 2 existing international scoping reviews summarize the characteristics of web-based interventions available for the treatment of depression in Canada in 2014 [<xref ref-type="bibr" rid="ref15">15</xref>] and anxiety in the United Kingdom in 2016 [<xref ref-type="bibr" rid="ref16">16</xref>]. The review of programs for depression by Renton et al [<xref ref-type="bibr" rid="ref15">15</xref>] identified 32 programs, with only 12 having published evidence of efficacy. Furthermore, the review of programs for anxiety by Ashford et al [<xref ref-type="bibr" rid="ref16">16</xref>] identified 34 programs, with only 17 having published evidence of efficacy. Given the rapid creation of web-based mental health resources in recent years [<xref ref-type="bibr" rid="ref27">27</xref>] and the tendency for web-based mental health programs to change, arise, and disappear with the provision or withdrawal of funding, there is a need for updated information on interventions that consumers and clinicians are likely to come across via search engines in the Australian context. Of particular benefit to clinicians would be a focus on free and publicly available interventions, based on evidence-based therapeutic approaches, that Australians can immediately find or be referred to. Clinicians have also indicated that it would be useful to include web-based interventions for adults seeking help for <italic>general mental well-being</italic> and <italic>suicidal ideation</italic>, which are issues commonly encountered in clinical practice but not covered by past reviews. We note that many reviews of the evidence for web-based interventions for specific disorders (eg, depression [<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref31">31</xref>]) and for specific populations (eg, adolescents and young adults [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref33">33</xref>]) have been undertaken in recent years. Although these are helpful for researchers and intervention developers, they are less likely to meet the practical information needs of consumers and clinicians, as many of the interventions contained in the reviews are not available outside research settings, and others that are publicly accessible, have not been evaluated and therefore are not included in the reviews.</p>
      </sec>
      <sec>
        <title>Objectives</title>
        <p>The purpose of this research is to identify the scope of and evidence for web-based mental health interventions addressing depression, anxiety, suicidal ideation, or general mental well-being that are currently available for free to Australian adults, and in doing so, develop a quick reference guide for GPs and mental health clinicians. It seeks to answer the following questions [<xref ref-type="bibr" rid="ref34">34</xref>]:</p>
        <list list-type="order">
          <list-item>
            <p>What web-based interventions addressing depression, anxiety, suicidal ideation, or general mental well-being are currently freely available (ie, at no cost and open to Australians) in Australia?</p>
          </list-item>
          <list-item>
            <p>What are the key gaps?</p>
          </list-item>
          <list-item>
            <p>What are the characteristics, including evidence of impact, credibility, and accessibility, of the interventions that are available?</p>
          </list-item>
        </list>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <p>This scoping review was conducted in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) [<xref ref-type="bibr" rid="ref35">35</xref>]. The study protocol was registered in the Open Science Framework [<xref ref-type="bibr" rid="ref36">36</xref>].</p>
      <sec>
        <title>Eligibility Criteria</title>
        <p>Eligible interventions were those that (1) targeted depression, anxiety, suicidal ideation, or general mental well-being (eg, resilience and stress); (2) were web-based; (3) had an interactive component (ie, the delivery of content was not entirely in a passive manner); (4) were designed for adults; (5) were free (ie, at no cost) and publicly available (including via registration, application, or referral from a health care professional); (6) were available in English; and (7) were based on an evidence-based therapeutic approach.</p>
        <p>Interventions were excluded if (1) they were targeted at consumers with a primary general medical condition (eg, survivors of cancer); (2) solely provided reading materials on one of the inclusion outcomes (ie, psychoeducation) or only offered a single tool (eg, diary-keeping, mood-monitoring, and meditation) without relevant psychoeducation or explanation of a broader evidence-based therapeutic approach; (3) were targeted at health professionals for training purposes; (4) were part of a research project <italic>that restricted access</italic> or limited program availability; or (5) included classes that had to be attended in person.</p>
      </sec>
      <sec>
        <title>Search Strategy</title>
        <p>A search was conducted in October 2020 for key terms using Google (Australian version). As the previously published scoping review on web-based interventions for depression only found 1 additional website when searching Yahoo and Bing [<xref ref-type="bibr" rid="ref15">15</xref>], only Google was searched for this review. A total of 4 searches were conducted by searching the following keywords: <italic>depression</italic>, <italic>anxiety</italic>, <italic>suicide</italic>, and <italic>wellbeing</italic>. A search log was kept to record the number of hits for each search, as well as the number of websites that were included or excluded (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). The search was terminated for the terms after searching the first 10 pages of results (ie, approximately 100 hits per keyword). Cookies and existing search histories were deleted before the start of each search, and the search results were downloaded into a Microsoft Excel file using a Chrome extension (ie, Export Search Results).</p>
        <p>In addition, key intervention databases were searched by 2 reviewers (SvdK and SL). These included Beacon [<xref ref-type="bibr" rid="ref37">37</xref>], Head to Health [<xref ref-type="bibr" rid="ref38">38</xref>], and eMHPrac websites [<xref ref-type="bibr" rid="ref39">39</xref>]. Finally, the reference lists and programs listed in the 2 existing scoping reviews on web-based depression [<xref ref-type="bibr" rid="ref15">15</xref>] and anxiety [<xref ref-type="bibr" rid="ref16">16</xref>] resources were searched by 2 reviewers (SvdK and SL) to identify any programs not included in the searches outlined. An overview of program developers and website links is provided in <xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>.</p>
      </sec>
      <sec>
        <title>Selection of Web-Based Programs</title>
        <p>Screening of the search results to identify eligible web-based programs was completed in 2 stages. The first stage involved screening all search hyperlinks by 1 reviewer (SvdK) to eliminate websites that solely provided information on 1 of the outcomes or those that were clearly irrelevant (eg, mental health information only websites, YouTube videos, or blogs). The remainder of the websites was then divided into those that directly offered web-based programs and those that linked to web-based programs. Any duplicate websites were removed. The second stage involved screening potential eligible programs against the eligibility criteria by 2 reviewers (SvdK and SL; <xref rid="figure1" ref-type="fig">Figure 1</xref>).</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagram of program selection.</p>
          </caption>
          <graphic xlink:href="mental_v9i2e31018_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Data Extraction</title>
        <p>A data extraction form was created to systematically evaluate each identified program. The extraction tool was adapted from a previously published framework designed to evaluate and report internet intervention studies [<xref ref-type="bibr" rid="ref40">40</xref>]. This framework has been used in 2 recent scoping reviews examining web-based interventions for depression [<xref ref-type="bibr" rid="ref15">15</xref>] and anxiety [<xref ref-type="bibr" rid="ref16">16</xref>]. The main categories and subcategories of investigation were adapted from these studies (<xref ref-type="table" rid="table1">Table 1</xref>).</p>
        <p>Websites were trialed and data extraction was undertaken by 3 reviewers (SvdK, SL, and GS) in November to December 2020, with the reviewers independently extracting data for each website so that the data extraction was performed in duplicate. Discrepancies in coding were resolved by discussion and, where necessary, investigated by the third reviewer. Where necessary, program authors were contacted to request access to the program. For 2 websites (MindSpot and Evolution Health), information was extracted from the public-facing pages where possible, and the remaining information was requested from the website authors or developers because of time and administrative constraints.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Data extraction categories.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="250"/>
            <col width="720"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Main categories and subcategories</td>
                <td>Evaluation focus</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="3">
                  <bold>Website characteristics</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Accessibility and credibility</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>How is the website accessed (free, via assessment, or via referral from a health care professional)?</p>
                    </list-item>
                    <list-item>
                      <p>Registration requirement (if yes, what information is collected?)</p>
                    </list-item>
                    <list-item>
                      <p>Mobile phone rendering (yes or no)</p>
                    </list-item>
                    <list-item>
                      <p>Advertisements (if yes, relevant or irrelevant?)</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Authorship details</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Presented contact details of authors or developers? (yes or no)</p>
                    </list-item>
                    <list-item>
                      <p>Country of origin</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Program characteristics</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Focus and target population</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Target issue</p>
                    </list-item>
                    <list-item>
                      <p>Target audience</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Professional support</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Therapist support (within the intervention, ability to link independent clinicians with the program)</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Other support</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Peer support (did the program offer peer support, eg, forums? Was this monitored)?</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Program interactivity</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>This facet is addressed by type and dose of intervention</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Multimedia channel of delivery</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Presentation format or mode of delivery (eg, how the content was delivered; text, audio, or video offered; use of character examples; and case scenarios)?</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Degree of synchronicity</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Were email or SMS text message reminders or follow-up offered?</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Audience reach</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>This facet is addressed in focus and target population</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Intervention characteristics</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Model of change</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Therapeutic approach</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Type and dose of intervention</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Was the program structured or unstructured?</p>
                    </list-item>
                    <list-item>
                      <p>Number of modules</p>
                    </list-item>
                    <list-item>
                      <p>Suggested or set treatment length</p>
                    </list-item>
                    <list-item>
                      <p>Self-assessments (were these mandatory or optional)?</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Intervention features</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Worksheets (yes or no)</p>
                    </list-item>
                    <list-item>
                      <p>Mood or symptom monitoring (yes or no)</p>
                    </list-item>
                    <list-item>
                      <p>Diary (yes or no)</p>
                    </list-item>
                    <list-item>
                      <p>Forums (yes or no)</p>
                    </list-item>
                    <list-item>
                      <p>Other features (if yes, specify)</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Empirical evidence</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Program evaluation</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Usability (did the program provide users with statistics on registered users, completion rates, attrition rates? Testimonial videos or case studies?)</p>
                    </list-item>
                    <list-item>
                      <p>Empirical evidence (searched program website and Beacon<sup>a</sup> database and contacted authors)</p>
                    </list-item>
                    <list-item>
                      <p>Type of evidence (eg, RCT<sup>b</sup>, pre, or post?)</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td colspan="3">
                  <bold>Ethical issues</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Website</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Privacy notice specified?</p>
                    </list-item>
                    <list-item>
                      <p>Terms and conditions specified?</p>
                    </list-item>
                  </list>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>Emergency</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Does the program offer links to crisis or emergency contacts?</p>
                    </list-item>
                  </list>
                </td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>Beacon is an Australian clinical web-based platform that describes different web-based self-help treatment programs.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>RCT: randomized controlled trial.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <p>To identify relevant peer-reviewed papers and thereby explore the empirical evidence behind each program, we checked the program websites and the Beacon directory and contacted the program authors. A total of 3 reviewers (SvdK, DHB, and GS) then conducted a rapid review of the peer-reviewed evidence for each program. This was limited to evaluations of the complete web-based program rather than individual program elements or individual modules. In addition, the level of evidence was determined for each peer-reviewed study [<xref ref-type="bibr" rid="ref41">41</xref>].</p>
      </sec>
      <sec>
        <title>Evaluation of Programs</title>
        <p>A program evaluation scoring system was adapted from previously published guidelines for evaluating and reporting web-based intervention research [<xref ref-type="bibr" rid="ref40">40</xref>], similar to Ashford et al [<xref ref-type="bibr" rid="ref16">16</xref>]. The scale comprised 17 yes or no closed-ended questions (<xref ref-type="boxed-text" rid="box1">Textbox 1</xref>). Questions that were answered <italic>yes</italic> were given a score of 1 and questions that were answered <italic>no</italic> were scored 0. Questions that could not be evaluated were given a score of 0. Questions that were not relevant to the website were excluded from the final score (listed as “NA”). The final scores were calculated as a percentage of the number of relevant items for that website. A total of 3 reviewers (SvdK, SL, and GS) independently assessed the programs against the evaluation scoring system. Discrepancies were resolved through discussion.</p>
        <boxed-text id="box1" position="float">
          <title>Program evaluation criteria (subcategories and questions).</title>
          <p>
            <bold>Authorship details</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Were the names and credentials of authors or organizations present?</p>
            </list-item>
            <list-item>
              <p>Were contact details provided?</p>
            </list-item>
            <list-item>
              <p>Was country of origin stated?</p>
            </list-item>
          </list>
          <p>
            <bold>Focus and target population</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Was the primary focus, goals, or objectives of the intervention stated?</p>
            </list-item>
            <list-item>
              <p>Was the target audience or mental health issue defined?</p>
            </list-item>
          </list>
          <p>
            <bold>Professional support</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Was there a statement of professional support (ie, clinicians involved in website development)?</p>
            </list-item>
          </list>
          <p>
            <bold>Multimedia channel of delivery</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Did the program offer a multimedia content delivery (ie, a combination of text, video, graphics, and audio formats)?</p>
            </list-item>
          </list>
          <p>
            <bold>Model of change</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Was the model of change (ie, type of therapy used) defined or stated?</p>
            </list-item>
          </list>
          <p>
            <bold>Type and dose of intervention</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Were the number of modules or time to complete each module stated?</p>
            </list-item>
            <list-item>
              <p>Was the intervention tailored to the user or was it generic for all users (ie, was the program content individualized with username, characteristics, previous responses)?</p>
            </list-item>
            <list-item>
              <p>Was the program easy to navigate (eg, clear links to the home page and easily able to stop or start the program)?</p>
            </list-item>
            <list-item>
              <p>Was the information on what is covered in the intervention modules provided (ie, names of modules or a short description)?</p>
            </list-item>
          </list>
          <p>
            <bold>Program evaluation</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Was evidence for the program provided to the user (ie, attrition data, success rate, completion rate, or number of users in the program or testimonials)?</p>
            </list-item>
            <list-item>
              <p>Has the program been empirically evaluated?</p>
            </list-item>
          </list>
          <p>
            <bold>Ethical issues</bold>
          </p>
          <list list-type="bullet">
            <list-item>
              <p>Was a unique username or password provided to users?</p>
            </list-item>
            <list-item>
              <p>Was a privacy notice specified?</p>
            </list-item>
            <list-item>
              <p>Were the terms and conditions specified?</p>
            </list-item>
          </list>
        </boxed-text>
      </sec>
      <sec>
        <title>Synthesis of Results</title>
        <p>The results were summarized quantitatively by main categories and subcategories, as displayed in <xref ref-type="table" rid="table1">Table 1</xref>. Where possible, descriptive statistics were used to summarize these findings.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Selection of Web-Based Programs</title>
        <p>As seen in <xref rid="figure1" ref-type="fig">Figure 1</xref>, 450 websites were screened through Google search, and an additional 13 websites were identified through database searches. Approximately 10.6% (49/463) of websites with links to potentially eligible programs and 39 potentially eligible programs were identified. Of the 49 websites, 25 (51%) program websites were screened for eligibility, of which 16 (64%) websites (leading to 52 programs) were included in the review. Of the 52 programs, 20 (39%) programs were classified as <italic>web-based interactive</italic>, and 32 (62%) programs were classified as <italic>web-based with downloadable worksheets/resources</italic>. These 2 types of programs were separated in the summary tables.</p>
        <p>We only found 2 programs (BeyondNow and My Digital Health iConsider Life) designed to address distress in the context of suicidal ideation. It should be noted that the inclusion of BeyondNow was debated between team members, as we experienced difficulty in determining whether it fully fulfills the criteria of using an evidence-based therapeutic approach. Nonetheless, it is considered a valuable tool for the management of suicide ideation; therefore, it was included in this review.</p>
      </sec>
      <sec>
        <title>Website Characteristics</title>
        <sec>
          <title>Accessibility and Credibility</title>
          <p>Of the 52 programs, 36 (69%) were available at no cost and open to all Australians, 9 (17%) were accessible via referral from a health care professional (via This Way Up), 4 (8%) required an assessment before registration (via MindSpot), and 3 (6%) required sign-up to a research project (via My Digital Health; <xref ref-type="table" rid="table2">Tables 2</xref> and <xref ref-type="table" rid="table3">3</xref>). A free website (with 5/52, 10% programs) provided users with access to the basic course content without payment but required a paid upgrade to access additional features (Living Life to the Full). In total, 8% (4/52) of courses from Evolution Health were free to users. In addition, Evolution Health is a technology provider that licenses paid white label versions of its platform to organizations that contain only the course that the organization wants (eg, the smoking cessation course), thereby creating a <italic>tailored</italic> version of the platform for those organizations to distribute freely to their members.</p>
          <p>Registration was required by 83% (43/52) of programs and most often required users’ names, emails, location (country, city, or postcode), and age. Approximately 6% (3/52) of programs created by My Digital Health were offered as part of a research study; of these, 2 programs, Life Flex and Life Flex–LGBQ (lesbian, gay, bisexual, and queer), required the completion of comprehensive demographic, mental health, and well-being questionnaires before access was granted. Approximately 17% (9/52) of programs did not require registration and allowed users anonymous access. All websites were accessible via mobile phones and did not contain advertisements, except for the 5 Living Life to the Full programs, which contained advertisements for e-books related to the course content.</p>
          <table-wrap position="float" id="table2">
            <label>Table 2</label>
            <caption>
              <p>Program characteristics of web-based interactive programs.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="30"/>
              <col width="150"/>
              <col width="200"/>
              <col width="200"/>
              <col width="200"/>
              <col width="220"/>
              <thead>
                <tr valign="bottom">
                  <td colspan="2">Program</td>
                  <td>Focus and target population (if specified)</td>
                  <td>Access</td>
                  <td>Therapist support</td>
                  <td>Presentation format</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Depression</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Depression Program</td>
                  <td>Depression, ≥16 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mum2B—MoodBooster</td>
                  <td>Depression during pregnancy, expectant mothers</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MumMood—Booster</td>
                  <td>Postnatal depression, women with postnatal depression</td>
                  <td>Free</td>
                  <td>Yes, optional</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>OnTrack—Depression</td>
                  <td>Depression, ≥18 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Anxiety</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Anxiety and Worry Program</td>
                  <td>Anxiety and worry, ≥16 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow</p>
                      </list-item>
                      <list-item>
                        <p>Format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Social Anxiety Program</td>
                  <td>Social anxiety, ≥16 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Multi-issue</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Indigenous Wellbeing</td>
                  <td>Managing depression and anxiety, Aboriginal and Torres Strait Islanders, ≥18 years</td>
                  <td>Free following mandatory assessment and contact with MindSpot therapist</td>
                  <td>Yes, optional access to MindSpot therapist</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Mood Mechanic</td>
                  <td>Managing depression and anxiety, young adults, 18-25 years</td>
                  <td>Free following mandatory assessment and contact with MindSpot therapist</td>
                  <td>Yes, optional access to MindSpot therapist</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Wellbeing</td>
                  <td>Managing depression and anxiety, 26-65 years</td>
                  <td>Free following mandatory assessment and contact with MindSpot therapist</td>
                  <td>Yes, optional access to MindSpot therapist</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Wellbeing Plus</td>
                  <td>Managing depression and anxiety, ≥60 years</td>
                  <td>Free following mandatory assessment and contact with MindSpot therapist</td>
                  <td>Yes, optional access to MindSpot therapist</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MoodGym</td>
                  <td>Anxiety and depression</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MyCompass</td>
                  <td>Mild to moderate depression, anxiety and stress, ≥18 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>My Digital Health—Life Flex</td>
                  <td>Anxiety or depression, ≥18 years</td>
                  <td>Free (via research study participation)</td>
                  <td>Yes, ability to connect independent clinician to program</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>My Digital Health—Life Flex LGBQ<sup>a</sup></td>
                  <td>Anxiety or depression, ≥18 years who are part of the LGBQ community</td>
                  <td>Free (via research study participation)</td>
                  <td>Yes, ability to connect independent clinician to program</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>General well-being</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Bereavement and Loss Program</td>
                  <td>Bereavement and loss, ≥16 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Divorce and separation</td>
                  <td>Divorce and separation, ≥16 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>ifarmwell</td>
                  <td>Well-being, farmers, ≥18 years</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>The Desk</td>
                  <td>Well-being, Australian tertiary students</td>
                  <td>Free</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Suicidal ideation</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>My Digital Health—iConsiderLife</td>
                  <td>Decision support crisis digital health program, ≥18 years</td>
                  <td>Free (via research study participation)</td>
                  <td>No</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>BeyondNow</td>
                  <td>Suicide safety planning</td>
                  <td>Free</td>
                  <td>N/A<sup>b</sup></td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Workbook or planner</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table2fn1">
                <p><sup>a</sup>LGBQ: lesbian, gay, bisexual, and queer.</p>
              </fn>
              <fn id="table2fn2">
                <p><sup>b</sup>N/A: not applicable.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
          <table-wrap position="float" id="table3">
            <label>Table 3</label>
            <caption>
              <p>Program characteristics of web-based programs with downloadable worksheets or resources.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="30"/>
              <col width="230"/>
              <col width="0"/>
              <col width="210"/>
              <col width="0"/>
              <col width="150"/>
              <col width="0"/>
              <col width="150"/>
              <col width="0"/>
              <col width="230"/>
              <thead>
                <tr valign="bottom">
                  <td colspan="3">Program</td>
                  <td colspan="2">Focus and target population (if specified)</td>
                  <td colspan="2">Access</td>
                  <td colspan="2">Therapist support</td>
                  <td>Presentation format</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td colspan="10">
                    <bold>Depression</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI<sup>a</sup>—Depression</td>
                  <td colspan="2">Depression</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text workbook with images</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Overcoming Depression</td>
                  <td colspan="2">Depression, ≥16 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Not in free version</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text</p>
                      </list-item>
                      <list-item>
                        <p>Gamified quiz</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental health Online—Depression Online Program</td>
                  <td colspan="2">Depression, ≥18 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Yes, optional access to e-therapists</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—The Depression Course</td>
                  <td colspan="2">Depression, ≥18 years</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Students Against Depression</td>
                  <td colspan="2">Depression, students</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="10">
                    <bold>Anxiety</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Health and Anxiety</td>
                  <td colspan="2">Health anxiety</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text workbook with images</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Panic</td>
                  <td colspan="2">Panic attacks</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text workbook with images</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Social Anxiety</td>
                  <td colspan="2">Social anxiety</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text workbook with images</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Worry and Rumination</td>
                  <td colspan="2">Worry</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text workbook with images</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Overcoming Anxiety</td>
                  <td colspan="2">Anxiety, ≥16 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Not in free version</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text</p>
                      </list-item>
                      <list-item>
                        <p>Gamified quiz</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Managing Anxiety Course</td>
                  <td colspan="2">Anxiety, ≥16 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Not in free version</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text</p>
                      </list-item>
                      <list-item>
                        <p>Gamified quiz</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—GAD<sup>b</sup> program</td>
                  <td colspan="2">GAD, ≥18 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Yes, optional access to e-therapists</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—Panic STOP!</td>
                  <td colspan="2">Panic attacks, ≥18 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Yes, optional access to e-therapists</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—Social Anxiety Online Program</td>
                  <td colspan="2">Social anxiety, ≥18 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Yes, optional access to e-therapists</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Health Anxiety Course</td>
                  <td colspan="2">Worry about health, ≥18 years</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Panic Attacks Course</td>
                  <td colspan="2">Panic attacks, ≥18 years</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Social Anxiety Course</td>
                  <td colspan="2">Social anxiety, ≥18 years</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Worry Course (GAD)</td>
                  <td colspan="2">GAD, ≥18 years</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="10">
                    <bold>Multi-issue</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—Made-4-Me Program</td>
                  <td colspan="2">Can pick up to 3 areas: depression, GAD, panic disorder, PTSD<sup>c</sup>, social anxiety, OCD<sup>d</sup>, ≥18 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Yes, optional access to e-therapists</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Mindfulness-Based CBT<sup>e</sup> Course</td>
                  <td colspan="2">Depression and anxiety, ≥18 years</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Mixed Depression and Anxiety Course</td>
                  <td colspan="2">Depression and anxiety, ≥18 years</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—MUMentum Pregnancy</td>
                  <td colspan="2">Anxiety and low mood, adults &#60;36 week pregnant</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—MUMentum Postnatal</td>
                  <td colspan="2">Anxiety and low mood, adults &#62;36 weeks pregnant or have given birth within the last 12 months</td>
                  <td colspan="2">Free when referred by clinician</td>
                  <td colspan="2">Yes, independent clinician allowed access</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Characters or case scenarios</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="10">
                    <bold>General</bold>
                    <bold>well-being</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Tolerating Distress</td>
                  <td colspan="2">Distress</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text workbook with images</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Grief and Loss</td>
                  <td colspan="2">Grief, ≥16 years</td>
                  <td colspan="2">Free</td>
                  <td colspan="2">Not in free version</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text</p>
                      </list-item>
                      <list-item>
                        <p>Gamified quiz</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full for Adults</td>
                  <td colspan="2">Emotional well-being, adults</td>
                  <td colspan="2">Free for the basic course; can upgrade for a fee</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full for Farming Communities</td>
                  <td colspan="2">Emotional well-being, farming communities</td>
                  <td colspan="2">Free for the basic course; can upgrade for a fee</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full with God</td>
                  <td colspan="2">Emotional well-being, people of faith</td>
                  <td colspan="2">Free for the basic course; can upgrade for a fee</td>
                  <td colspan="2">No</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Text-based</p>
                      </list-item>
                      <list-item>
                        <p>Graphics</p>
                      </list-item>
                      <list-item>
                        <p>Audio or video</p>
                      </list-item>
                      <list-item>
                        <p>Comic slideshow format</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table3fn1">
                <p><sup>a</sup>CCI: Center for Clinical Interventions.</p>
              </fn>
              <fn id="table3fn2">
                <p><sup>b</sup>GAD: generalized anxiety disorder.</p>
              </fn>
              <fn id="table3fn3">
                <p><sup>c</sup>PTSD: posttraumatic stress disorder.</p>
              </fn>
              <fn id="table3fn4">
                <p><sup>d</sup>OCD: obsessive compulsive disorder.</p>
              </fn>
              <fn id="table3fn5">
                <p><sup>e</sup>CBT: cognitive behavioral therapy.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
        </sec>
        <sec>
          <title>Authorship Details</title>
          <p>The review was limited to programs that were <italic>accessible</italic> to Australians. Unsurprisingly, most of these programs identified Australia as their country of origin (40/52, 77%), although other countries of origin were Scotland (5/52, 10%), Canada (4/52, 8%), the United States (in collaboration with Australia; 2/52, 4%) and the United Kingdom (1/52, 2%). Contact details for the authors or developers were provided by almost all websites (51/52, 98%). An overview of program developers and website links is provided in <xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>.</p>
        </sec>
      </sec>
      <sec>
        <title>Program Characteristics</title>
        <p><xref ref-type="table" rid="table2">Table 2</xref> provides an overview of program characteristics for web-based interactive programs and <xref ref-type="table" rid="table3">Table 3</xref> for web-based programs with downloadable worksheets or resources.</p>
        <sec>
          <title>Focus and Target Population</title>
          <p>Overall, 17% (9/52) of programs specifically addressed depression, 29% (15/52) of programs addressed anxiety, 25% (13/52) of programs addressed multiple issues, 25% (13/52) of programs addressed general well-being, and 4% (2/52) of programs addressed suicidal ideation. Most programs specifically stated that their target audience was the general adult population (aged ≥16 years or ≥18 years; 26/52, 50%), with other (9/52, 17%) programs not specifying a target group but appearing to be designed for adults, based on content. Several programs were designed for specific target populations, including expectant mothers or new parents (6/52, 12%), tertiary students (3/52, 6%), farmers or rural communities (2/52, 4%), church-going adults (1/52, 2%), the LGBQ community (1/52, 2%), Aboriginal and Torres Strait Islander people (1/52, 2%), young adults (1/52, 2%), adults aged 26 to 65 years (1/52, 2%), and older adults (1/52, 2%).</p>
        </sec>
        <sec>
          <title>Support and Features</title>
          <p>Approximately 88% (46/52) of programs provided a statement of professional support, that is, mental health clinicians or researchers were involved in the programs’ development. Of the 52 programs, 11 (21%) programs allowed users to invite their independent clinician to monitor their progress in the course, and a further 10 (19%) programs offered optional therapist support while engaging in the program. Approximately 8% (4/52) of programs (Evolution Health) did not offer therapist support through the free version of their programs; however, therapist support was an optional inclusion for paid versions of the program licensed to organizations. Only 8% (4/52) of programs (Evolution Health) enabled peer support, such as through forums, and in all cases, this was expert-moderated. Most programs offered multiple forms of information delivery, with text, graphics, audio or video, characters, and case scenarios as common features. Email or SMS text message reminders were available 60% (31/52) of the programs.</p>
        </sec>
      </sec>
      <sec>
        <title>Intervention Characteristics</title>
        <sec>
          <title>Overview</title>
          <p>The intervention characteristics of web-based interactive programs and web-based programs with downloadable worksheets or resources are shown in <xref ref-type="table" rid="table4">Tables 4</xref> and <xref ref-type="table" rid="table5">5</xref>, respectively.</p>
          <table-wrap position="float" id="table4">
            <label>Table 4</label>
            <caption>
              <p>Intervention characteristics of web-based interactive programs.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="30"/>
              <col width="240"/>
              <col width="150"/>
              <col width="150"/>
              <col width="180"/>
              <col width="250"/>
              <thead>
                <tr valign="bottom">
                  <td colspan="2">Program</td>
                  <td>Therapeutic approach</td>
                  <td>Program structure</td>
                  <td>Modules (length)</td>
                  <td>Intervention features</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Depression</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Depression Program</td>
                  <td>CBT<sup>a</sup>+IPT<sup>b</sup></td>
                  <td>Structured</td>
                  <td>3 sections</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mum2B—MoodBooster</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>6 modules (6 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MumMood—Booster</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>6 modules (6 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>OnTrack—Depression</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>6 modules (8 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Anxiety</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Anxiety and Worry Program</td>
                  <td>CBT+IPT</td>
                  <td>Structured</td>
                  <td>3 sections</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Social Anxiety Program</td>
                  <td>CBT+IPT</td>
                  <td>Unstructured</td>
                  <td>6 sections</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Multi-issue</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Indigenous Wellbeing</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>5 modules (8 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Mood Mechanic</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>5 modules (8 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Wellbeing</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>5 modules (8 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MindSpot—Wellbeing Plus</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>5 modules (8 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MoodGym</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>5 modules</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>MyCompass</td>
                  <td>CBT+ IPT+positive psychology</td>
                  <td>Unstructured</td>
                  <td>14 activities (recommend 7 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>My Digital Health—Life Flex</td>
                  <td>Biopsychosocial approach+CBT+positive psychology</td>
                  <td>Structured (optional or mandatory depending on RCT<sup>c</sup> arm)</td>
                  <td>7 modules (scheduled release over 7 weeks in 1 RCT arm)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                      <list-item>
                        <p>Option to connect Fitbit or other health monitoring tools</p>
                      </list-item>
                      <list-item>
                        <p>Safety planning tool</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>My Digital Health—Life Flex LGBQ<sup>d</sup></td>
                  <td>Biopsychosocial approach+CBT+positive psychology</td>
                  <td>Structured (optional or mandatory depending on RCT arm)</td>
                  <td>7 modules (scheduled release over 7 weeks in 1 RCT arm)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                      <list-item>
                        <p>Option to connect Fitbit or other health monitoring tools</p>
                      </list-item>
                      <list-item>
                        <p>Safety planning tool</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>General well-being</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Bereavement and Loss Program</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>2 sections</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>eCouch—Divorce and Separation</td>
                  <td>CBT</td>
                  <td>Structured</td>
                  <td>3 sections</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>ifarmwell</td>
                  <td>ACT<sup>e</sup></td>
                  <td>Structured</td>
                  <td>5 modules (10 weeks)</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Personalized script</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>The Desk</td>
                  <td>CBT+mindfulness+positive psychology</td>
                  <td>Unstructured</td>
                  <td>4 modules</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="6">
                    <bold>Suicidal ideation</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>My Digital Health—iConsiderLife</td>
                  <td>No</td>
                  <td>Structured</td>
                  <td>6 pathways</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>BeyondNow</td>
                  <td>N/A<sup>f</sup></td>
                  <td>Unstructured</td>
                  <td>No modules</td>
                  <td>
                    <list list-type="bullet">
                      <list-item>
                        <p>Process of completing plan is like a worksheet</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table4fn1">
                <p><sup>a</sup>CBT: cognitive behavioral therapy.</p>
              </fn>
              <fn id="table4fn2">
                <p><sup>b</sup>IPT: interpersonal psychotherapy.</p>
              </fn>
              <fn id="table4fn3">
                <p><sup>c</sup>RCT: randomized controlled trial.</p>
              </fn>
              <fn id="table4fn4">
                <p><sup>d</sup>LGBQ: lesbian, gay, bisexual, and queer.</p>
              </fn>
              <fn id="table4fn5">
                <p><sup>e</sup>ACT: acceptance and commitment therapy.</p>
              </fn>
              <fn id="table4fn6">
                <p><sup>f</sup>N/A: not applicable.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
          <table-wrap position="float" id="table5">
            <label>Table 5</label>
            <caption>
              <p>Intervention characteristics of web-based programs with downloadable worksheets or resources.</p>
            </caption>
            <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
              <col width="30"/>
              <col width="240"/>
              <col width="0"/>
              <col width="150"/>
              <col width="0"/>
              <col width="150"/>
              <col width="0"/>
              <col width="180"/>
              <col width="0"/>
              <col width="250"/>
              <thead>
                <tr valign="bottom">
                  <td colspan="3">Program</td>
                  <td colspan="2">Therapeutic approach</td>
                  <td colspan="2">Program structure</td>
                  <td colspan="2">Modules (length)</td>
                  <td>Intervention features</td>
                </tr>
              </thead>
              <tbody>
                <tr valign="top">
                  <td colspan="10">
                    <bold>Depression</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI<sup>a</sup>—Depression</td>
                  <td colspan="2">CBT<sup>b</sup></td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">9 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Overcoming Depression</td>
                  <td colspan="2">CBT+motivational interviewing</td>
                  <td colspan="2">Structured but not mandatory to follow structure</td>
                  <td colspan="2">9 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Experiments to try</p>
                      </list-item>
                      <list-item>
                        <p>Symptom tracker diary</p>
                      </list-item>
                      <list-item>
                        <p>Optional self-assessments</p>
                      </list-item>
                      <list-item>
                        <p>Member forum</p>
                      </list-item>
                      <list-item>
                        <p>Messaging with others</p>
                      </list-item>
                      <list-item>
                        <p>Goal setting</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—Depression Online Program</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">11 modules (recommend 12 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—The Depression Course</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">6 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Students Against Depression</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">6 modules (recommend 6 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                      <list-item>
                        <p>Safety planning tool</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="10">
                    <bold>Anxiety</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Health and Anxiety</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">9 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Panic</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">12 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Social Anxiety</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">10 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Worry and Rumination</td>
                  <td colspan="2">Metacognitive therapy</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">10 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Overcoming Anxiety</td>
                  <td colspan="2">CBT+motivational interviewing</td>
                  <td colspan="2">Structured but not mandatory to follow structure</td>
                  <td colspan="2">9 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Experiments to try</p>
                      </list-item>
                      <list-item>
                        <p>Mood tracker diary</p>
                      </list-item>
                      <list-item>
                        <p>Optional self-assessments</p>
                      </list-item>
                      <list-item>
                        <p>Member forum</p>
                      </list-item>
                      <list-item>
                        <p>Messaging with others</p>
                      </list-item>
                      <list-item>
                        <p>Goal setting</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Managing Anxiety Course</td>
                  <td colspan="2">CBT+motivational interviewing</td>
                  <td colspan="2">Structured but not mandatory to follow structure</td>
                  <td colspan="2">1 module</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Experiments to try</p>
                      </list-item>
                      <list-item>
                        <p>Optional self-assessments</p>
                      </list-item>
                      <list-item>
                        <p>Member forum</p>
                      </list-item>
                      <list-item>
                        <p>Messaging with others</p>
                      </list-item>
                      <list-item>
                        <p>Goal setting</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—GAD<sup>c</sup> Program</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">12 modules (recommend 12 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—Panic STOP!</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">12 modules (recommend 12 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—Social Anxiety Online Program</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">12 modules (recommend 12 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Health Anxiety Course</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">6 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Panic Attacks Course</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">6 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Social Anxiety Course</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">6 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Worry Course (GAD)</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">6 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="10">
                    <bold>Multi-issue</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Mental Health Online—Made-4-Me Program</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">11 modules (recommend 12 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                    </list>
                    <break/>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Mindfulness-based CBT Course</td>
                  <td colspan="2">CBT+mindfulness</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">6 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Mixed Depression and Anxiety Course</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">6 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—MUMentum Pregnancy</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">3 modules (4-6 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—MUMentum Postnatal</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">3 modules (4-6 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td colspan="10">
                    <bold>General well-being</bold>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>CCI—Tolerating Distress</td>
                  <td colspan="2">DBT<sup>d</sup></td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">4 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Evolution Health—Grief and Loss</td>
                  <td colspan="2">CBT+motivational interviewing</td>
                  <td colspan="2">Structured but not mandatory to follow structure</td>
                  <td colspan="2">1 module</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Experiments to try</p>
                      </list-item>
                      <list-item>
                        <p>Optional self-assessments</p>
                      </list-item>
                      <list-item>
                        <p>Member forum</p>
                      </list-item>
                      <list-item>
                        <p>Messaging with others</p>
                      </list-item>
                      <list-item>
                        <p>Goal setting</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full for Adults</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">8 modules (recommend 8 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Blog</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full for Farming Communities</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">5 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                      <list-item>
                        <p>Blog</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full with God</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">8 modules (recommend 8 weeks)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Diary</p>
                      </list-item>
                      <list-item>
                        <p>Blog</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full —Enjoy Your Baby</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">5 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Blog</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>Living Life to the Full —Enjoy Your Bump</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured, optional</td>
                  <td colspan="2">5 modules</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Blog</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—Coping with Stress Course</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">4 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder feature</p>
                      </list-item>
                      <list-item>
                        <p>Calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
                <tr valign="top">
                  <td>
                    <break/>
                  </td>
                  <td>This Way Up—The Student Wellbeing Course</td>
                  <td colspan="2">CBT</td>
                  <td colspan="2">Structured</td>
                  <td colspan="2">8 modules (3 months)</td>
                  <td colspan="2">
                    <list list-type="bullet">
                      <list-item>
                        <p>Worksheets</p>
                      </list-item>
                      <list-item>
                        <p>Mood or symptom monitoring</p>
                      </list-item>
                      <list-item>
                        <p>Reminder or calendar feature</p>
                      </list-item>
                    </list>
                  </td>
                </tr>
              </tbody>
            </table>
            <table-wrap-foot>
              <fn id="table5fn1">
                <p><sup>a</sup>CCI: Centre for Clinical Interventions.</p>
              </fn>
              <fn id="table5fn2">
                <p><sup>b</sup>CBT: cognitive behavioral therapy.</p>
              </fn>
              <fn id="table5fn3">
                <p><sup>c</sup>GAD: generalized anxiety disorder.</p>
              </fn>
              <fn id="table5fn4">
                <p><sup>d</sup>DBT: dialectical behavior therapy.</p>
              </fn>
            </table-wrap-foot>
          </table-wrap>
        </sec>
        <sec>
          <title>Therapeutic Approach or Model of Change</title>
          <p>On the basis of either self-descriptions or the clinical judgment of the authors, 90% (47/52) of programs were based on cognitive behavioral therapy (CBT), either with 21% (11/52) or without 69% (36/52) other therapeutic approaches. In combination with CBT, some programs included motivational interviewing (4/52, 8%), interpersonal therapy (4/52, 8%), or mindfulness (1/52, 2%). Only 2% (1/52) of programs (ifarmwell) was based on acceptance and commitment therapy (ACT), 2% (1/52) of programs (Centre for Clinical Interventions [CCI]: Tolerating Distress) on dialectical behavior therapy (DBT), and 2% (1/52) of programs (BeyondNow) on problem solving (ie, how to keep self safe or safety planning).</p>
        </sec>
        <sec>
          <title>Type and Dose of Intervention</title>
          <p>In total, 48% (25/52) of programs were structured or <italic>tunneled</italic>, where participants were led through a series of modules or sessions in a specific order. A further 42% (22/52) of programs recommended to follow the program in a specific order but allowed users to choose the order in which they completed them. Approximately 4% (2/52) of programs were part of an RCT research project that had open access and allocated participants to 1 of 2 <italic>therapy structure</italic> conditions: mandatory (participants did not choose the order) or optional (participants were given the freedom to choose the order of completion). Approximately 6% (3/52) of programs were unstructured.</p>
          <p>The number of modules or activities offered within a program ranged from 1 to 14 (mean 6.51, SD 3.03), except for 1 program (BeyondNow), which offered a safety planner instead of modules. The recommended time to complete the modules ranged from 1 week to 3 months (specified for 34/52, 65% of programs). Approximately 33% (17/52) of programs did not recommend a set treatment length. Self-assessments were included in 79% (41/52) programs, and it was mandatory in 56% (29/52) of programs and optional in 23% (12/52) of programs.</p>
        </sec>
        <sec>
          <title>Intervention Features</title>
          <p>All programs, except 4% (2/52; The Desk and iConsider Life), featured worksheets, either within the web-based intervention or as downloadable forms to be completed offline. Diaries were featured in 46% (24/52) of programs, and 75% (39/52) of programs included some type of mood or symptom monitoring.</p>
        </sec>
      </sec>
      <sec>
        <title>Empirical Evidence: Program Evaluation</title>
        <p>Out of 17 possible evaluation items, 75% (39/52) of programs could be evaluated against all 17 items, 15% (8/52) against 94% (16/17) of items, and 10% (5/52) against 76% (13/17) of items (<xref ref-type="table" rid="table6">Table 6</xref>). In total, scores ranged from 44% to 100%, with an average score of 85% (SD 10.7%). More specifically, of the 75% (39/52) of programs that provided values for all 17 items, scores varied between 65% and 94%, with an average score of 87% (SD 7%). This was between 44% and 81%, with an average of 69% (SD 11%), for programs that provided values for 16 items, and between 85% and 100%, with an average of 95% (SD 7%), for programs that provided values for 13 items. Individual answers to the program evaluation criteria are shown in <xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref>.</p>
        <table-wrap position="float" id="table6">
          <label>Table 6</label>
          <caption>
            <p>Type of research conducted to evaluate eligible programs, including the level of evidence and process evaluation scores (N=52).</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="310"/>
            <col width="300"/>
            <col width="150"/>
            <col width="120"/>
            <col width="120"/>
            <thead>
              <tr valign="top">
                <td>Program</td>
                <td>Type of research evaluation studies</td>
                <td>Level of evidence<sup>a</sup></td>
                <td>Total number of relevant evaluation items, N</td>
                <td>Process evaluation score, n (%)<sup>b,c</sup></td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>BeyondNow</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Feasibility and effectiveness study [<xref ref-type="bibr" rid="ref42">42</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                  </list>
                </td>
                <td>13</td>
                <td>11 (85)</td>
              </tr>
              <tr valign="top">
                <td>CCI<sup>d</sup>—Depression</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon<sup>e</sup>: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—<sup>f</sup></td>
                <td>16</td>
                <td>11 (69)</td>
              </tr>
              <tr valign="top">
                <td>CCI—Health Anxiety</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Preliminary pre–post study [<xref ref-type="bibr" rid="ref43">43</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>16</td>
                <td>12 (75)</td>
              </tr>
              <tr valign="top">
                <td>CCI—Panic</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>16</td>
                <td>11 (69)</td>
              </tr>
              <tr valign="top">
                <td>CCI—Social Anxiety Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>16</td>
                <td>11 (69)</td>
              </tr>
              <tr valign="top">
                <td>CCI—Tolerating Distress</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>16</td>
                <td>11 (69)</td>
              </tr>
              <tr valign="top">
                <td>CCI—Worry and Rumination</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Preliminary pre–post study [<xref ref-type="bibr" rid="ref43">43</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>16</td>
                <td>12 (75)</td>
              </tr>
              <tr valign="top">
                <td>eCouch—Anxiety and Worry</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Adapted from MoodGym</p>
                    </list-item>
                  </list>
                  <list list-type="bullet">
                    <list-item>
                      <p>RCT<sup>g</sup> [<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>13 (76)</td>
              </tr>
              <tr valign="top">
                <td>eCouch—Bereavement and Loss</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Adapted from MoodGym</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>11 (65)</td>
              </tr>
              <tr valign="top">
                <td>eCouch—Depression</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Adapted from MoodGymRCT [<xref ref-type="bibr" rid="ref46">46</xref>-<xref ref-type="bibr" rid="ref50">50</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>13 (76)</td>
              </tr>
              <tr valign="top">
                <td>eCouch—Divorce and Separation</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Adapted from MoodGym</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>12 (71)</td>
              </tr>
              <tr valign="top">
                <td>eCouch—Social Anxiety</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Adapted from MoodGym</p>
                    </list-item>
                  </list>
                  <list list-type="bullet">
                    <list-item>
                      <p>2-group RCT and to assess effectiveness and cost-effectiveness [<xref ref-type="bibr" rid="ref12">12</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Pre–post with control group and randomized [<xref ref-type="bibr" rid="ref51">51</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>14 (82)</td>
              </tr>
              <tr valign="top">
                <td>Evolution Health—Overcoming Anxiety</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Pre–post longitudinal study [<xref ref-type="bibr" rid="ref52">52</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Pilot RCT [<xref ref-type="bibr" rid="ref53">53</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>User characteristics [<xref ref-type="bibr" rid="ref54">54</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Evolution Health—Overcoming Depression</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>14 (82)</td>
              </tr>
              <tr valign="top">
                <td>Evolution Health—Grief and Loss</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>14 (82)</td>
              </tr>
              <tr valign="top">
                <td>Evolution Health—Managing Anxiety</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Pre–post longitudinal study [<xref ref-type="bibr" rid="ref52">52</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>ifarmwell</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: currently being evaluated</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Living Life to the Full for Adults</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Comparative clinical feasibility study [<xref ref-type="bibr" rid="ref55">55</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Feasibility [<xref ref-type="bibr" rid="ref56">56</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>Living Life to the Full for Farming Communities</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Living Life to the Full with God</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Living Life to the Full—Enjoy Your Baby</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Living Life to the Full—Enjoy Your Bump</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Mental Health Online—Depression Online</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Uncontrolled pre–post treatment study [<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Mental Health Online—Generalized Anxiety Disorder</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Uncontrolled pre–post treatment study [<xref ref-type="bibr" rid="ref57">57</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Pre–post treatment [<xref ref-type="bibr" rid="ref59">59</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Pre- to posttreatment quasi-experimental (participant choice) [<xref ref-type="bibr" rid="ref60">60</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Mental Health Online—Made 4 Me</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Mental Health Online—Panic STOP!</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Uncontrolled pre–post treatment study [<xref ref-type="bibr" rid="ref57">57</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Pre–post treatment [<xref ref-type="bibr" rid="ref59">59</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Participant choice quasi-experimental trial [<xref ref-type="bibr" rid="ref60">60</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Mental Health Online—Social Anxiety Online</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Pre–post treatment study [<xref ref-type="bibr" rid="ref59">59</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Participant choice quasi-experimental trial [<xref ref-type="bibr" rid="ref60">60</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>MindSpot—Indigenous Wellbeing Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Prospective uncontrolled observational cohort study [<xref ref-type="bibr" rid="ref61">61</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level IV</p>
                    </list-item>
                  </list>
                </td>
                <td>13</td>
                <td>13 (100)</td>
              </tr>
              <tr valign="top">
                <td>MindSpot—Mood Mechanic Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Single-arm, open trial [<xref ref-type="bibr" rid="ref62">62</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref63">63</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>13</td>
                <td>13 (100)</td>
              </tr>
              <tr valign="top">
                <td>MindSpot—Wellbeing</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Cost-effectiveness [<xref ref-type="bibr" rid="ref64">64</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Feasibility trial [<xref ref-type="bibr" rid="ref65">65</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref66">66</xref>-<xref ref-type="bibr" rid="ref73">73</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>12-month follow-up RCT [<xref ref-type="bibr" rid="ref62">62</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Single group open trial [<xref ref-type="bibr" rid="ref74">74</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                  </list>
                </td>
                <td>13</td>
                <td>13 (100)</td>
              </tr>
              <tr valign="top">
                <td>MindSpot—Wellbeing Plus</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Cost-effectiveness [<xref ref-type="bibr" rid="ref75">75</xref>,<xref ref-type="bibr" rid="ref76">76</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Feasibility study [<xref ref-type="bibr" rid="ref75">75</xref>,<xref ref-type="bibr" rid="ref77">77</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Implementation [<xref ref-type="bibr" rid="ref78">78</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref75">75</xref>,<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref79">79</xref>,<xref ref-type="bibr" rid="ref80">80</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level II and III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>13</td>
                <td>13 (100)</td>
              </tr>
              <tr valign="top">
                <td>MoodGym</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Acceptability study [<xref ref-type="bibr" rid="ref81">81</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Implementation [<xref ref-type="bibr" rid="ref82">82</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Follow-up outcome analysis [<xref ref-type="bibr" rid="ref83">83</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Program use [<xref ref-type="bibr" rid="ref84">84</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCTs [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref81">81</xref>,<xref ref-type="bibr" rid="ref82">82</xref>,<xref ref-type="bibr" rid="ref85">85</xref>-<xref ref-type="bibr" rid="ref99">99</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>School or class trials [<xref ref-type="bibr" rid="ref100">100</xref>,<xref ref-type="bibr" rid="ref101">101</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Compliance [<xref ref-type="bibr" rid="ref102">102</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                    <list-item>
                      <p>Level III-2</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>Mum2BMoodBooster</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: currently being evaluated</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>14 (82)</td>
              </tr>
              <tr valign="top">
                <td>MumMoodBooster</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Acceptability study [<xref ref-type="bibr" rid="ref103">103</xref>,<xref ref-type="bibr" rid="ref104">104</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Feasibility study [<xref ref-type="bibr" rid="ref104">104</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref105">105</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>myCompass</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Feasibility study [<xref ref-type="bibr" rid="ref106">106</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref107">107</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref108">108</xref>-<xref ref-type="bibr" rid="ref110">110</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II-3</p>
                    </list-item>
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>My Digital Health—iConsiderLife</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: currently being evaluated</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>16</td>
                <td>13 (81)</td>
              </tr>
              <tr valign="top">
                <td>My Digital Health—Life Flex</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: currently being evaluated</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>My Digital Health—Life Flex LGBQ<sup>h</sup></td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: currently being evaluated</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>OnTrack—Depression</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>13 (76)</td>
              </tr>
              <tr valign="top">
                <td>The Desk</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>14 (82)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—Coping with Stress Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—The Depression Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Nonrandomized comparison study [<xref ref-type="bibr" rid="ref111">111</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref112">112</xref>-<xref ref-type="bibr" rid="ref117">117</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref111">111</xref>,<xref ref-type="bibr" rid="ref118">118</xref>-<xref ref-type="bibr" rid="ref124">124</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Adherence [<xref ref-type="bibr" rid="ref125">125</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-2</p>
                    </list-item>
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II-3</p>
                    </list-item>
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—Health Anxiety Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref126">126</xref>,<xref ref-type="bibr" rid="ref127">127</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref128">128</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way UpMindfulness-based CBT<sup>i</sup> Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref129">129</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref130">130</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—Mixed Depression and Anxiety Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref74">74</xref>,<xref ref-type="bibr" rid="ref111">111</xref>,<xref ref-type="bibr" rid="ref131">131</xref>-<xref ref-type="bibr" rid="ref133">133</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref72">72</xref>,<xref ref-type="bibr" rid="ref131">131</xref>,<xref ref-type="bibr" rid="ref134">134</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—MUMentum Pregnancy</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref135">135</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—MUMentum Postnatal</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref136">136</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—Panic Attacks Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref137">137</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref72">72</xref>,<xref ref-type="bibr" rid="ref138">138</xref>-<xref ref-type="bibr" rid="ref140">140</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—Social Anxiety Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref141">141</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref72">72</xref>,<xref ref-type="bibr" rid="ref138">138</xref>,<xref ref-type="bibr" rid="ref142">142</xref>-<xref ref-type="bibr" rid="ref146">146</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—Student Wellbeing Course</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: not specified</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>17</td>
                <td>15 (88)</td>
              </tr>
              <tr valign="top">
                <td>This Way Up—Worry Course (GAD<sup>j</sup>)</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Nonrandomized comparison study [<xref ref-type="bibr" rid="ref111">111</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>Open trial [<xref ref-type="bibr" rid="ref112">112</xref>,<xref ref-type="bibr" rid="ref133">133</xref>,<xref ref-type="bibr" rid="ref147">147</xref>,<xref ref-type="bibr" rid="ref148">148</xref>]</p>
                    </list-item>
                    <list-item>
                      <p>RCT [<xref ref-type="bibr" rid="ref71">71</xref>,<xref ref-type="bibr" rid="ref72">72</xref>,<xref ref-type="bibr" rid="ref138">138</xref>,<xref ref-type="bibr" rid="ref149">149</xref>-<xref ref-type="bibr" rid="ref151">151</xref>]</p>
                    </list-item>
                  </list>
                </td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Level III-2</p>
                    </list-item>
                    <list-item>
                      <p>Level III-3</p>
                    </list-item>
                    <list-item>
                      <p>Level II</p>
                    </list-item>
                  </list>
                </td>
                <td>17</td>
                <td>16 (94)</td>
              </tr>
              <tr valign="top">
                <td>Students Against Depression</td>
                <td>
                  <list list-type="bullet">
                    <list-item>
                      <p>Website: currently being evaluated</p>
                    </list-item>
                    <list-item>
                      <p>Beacon: not reviewed</p>
                    </list-item>
                  </list>
                </td>
                <td>—</td>
                <td>16</td>
                <td>7 (44)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table6fn1">
              <p><sup>a</sup>Level of evidence determined from the National Health and Medical Research Council evidence hierarchy by intervention studies [<xref ref-type="bibr" rid="ref41">41</xref>]; level I: systematic review; level II: randomized controlled trials; level III-1: pseudorandomized controlled trial; level III-2: comparative study with controls; level III-3: comparative study without controls; and level IV: case series.</p>
            </fn>
            <fn id="table6fn2">
              <p><sup>b</sup>A program evaluation scoring system was adapted from previously published guidelines for evaluating and reporting web-based intervention research [<xref ref-type="bibr" rid="ref40">40</xref>].</p>
            </fn>
            <fn id="table6fn3">
              <p><sup>c</sup>Owing to access restrictions, not all programs could be evaluated against all 17 items, which may have resulted in higher scores.</p>
            </fn>
            <fn id="table6fn4">
              <p><sup>d</sup>CCI: Centre for Clinical Interventions.</p>
            </fn>
            <fn id="table6fn5">
              <p><sup>e</sup>Beacon is an Australian clinical web-based platform that describes different web-based self-help treatment programs.</p>
            </fn>
            <fn id="table6fn6">
              <p><sup>f</sup>Evaluation studies are not available.</p>
            </fn>
            <fn id="table6fn7">
              <p><sup>g</sup>RCT: randomized controlled trial.</p>
            </fn>
            <fn id="table6fn8">
              <p><sup>h</sup>LGBQ: lesbian, gay, bisexual, and queer.</p>
            </fn>
            <fn id="table6fn9">
              <p><sup>i</sup>CBT: cognitive behavioral therapy.</p>
            </fn>
            <fn id="table6fn10">
              <p><sup>j</sup>GAD: generalized anxiety disorder.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <p>Evidence of the program’s usability (ie, attrition data, success rate, completion rate, or number of users in the program or testimonials) was provided for 52% (27/52) of programs. In many cases, where a website offered ≥1 program, these results were provided for the suite of programs listed on the website generally rather than for the specific programs (eg, Evolution Health and This Way Up). Approximately 56% (29/52) of programs were supported by some type of evaluation; 59% (17/29) had undergone effectiveness trials, and 41% (12/29) had empirical evidence of both effectiveness and acceptability (ie, level III and level IV evidence). Approximately 68% (19/29) of the evaluated programs had undergone evaluation via RCT (ie, level II evidence). Of the 23 programs without evaluation data, 6 (26%) are currently in the process of being evaluated. All 52 programs and the type of evaluation studies conducted, including the level of evidence, are shown in <xref ref-type="table" rid="table6">Table 6</xref> [<xref ref-type="bibr" rid="ref41">41</xref>]. A rapid review of the evidence for each of these programs’ evaluations is provided in <xref ref-type="supplementary-material" rid="app4">Multimedia Appendix 4</xref> [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref12">12</xref>,<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref151">151</xref>].</p>
      </sec>
      <sec>
        <title>Legal and Ethical Issues</title>
        <p>The vast majority of programs provided privacy notices (50/52, 96%) and terms and conditions (51/52, 98%). Approximately 88% (46/52) of programs provided crisis links in the form of telephone numbers for emergency services, numbers of helplines or links to websites, and other resources. Only 1 website did not offer crisis links for its programs (CCI); this website was developed by the Western Australian Department of Health to provide evidence-based web-based resources to support practitioners, as well as to provide self-help materials for individuals. The terms and conditions of the website state that the information is provided for information purposes only.</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>The purpose of this scoping review was to summarize the freely available web-based resources based on an evidence-based therapeutic approach for Australian adults seeking self-help for depression, anxiety, suicidal ideation, or general well-being. We sought to describe their characteristics, including therapeutic approaches, key features, and the quality of evidence behind them and thereby produce an accessible summary to inform clinicians’ selection of web-based interventions for their patients. This review builds on past reviews of web-based resources for depression [<xref ref-type="bibr" rid="ref15">15</xref>] and anxiety [<xref ref-type="bibr" rid="ref16">16</xref>]. To our knowledge, this is the first review of publicly available interventions that includes both suicidal ideation and general well-being.</p>
        <p>A total of 52 web-based programs were identified, of which 20 (39%) were classified as web-based interactive programs, and 32 (62%) were classified as web-based programs with downloadable worksheets or resources. Of these 52 programs, 29 (56%) had been empirically evaluated, and most of the evidence was assessed as level II or III studies. This is similar to past reviews, which found that 50% of the programs addressing anxiety had undergone empirical evaluation [<xref ref-type="bibr" rid="ref16">16</xref>], and 38% of programs addressing depression had been evaluated via an RCT (ie, level II studies) [<xref ref-type="bibr" rid="ref15">15</xref>]. A total of 6 additional programs in this review were also currently undergoing evaluation at the time of writing (ifarmwell, My Digital Health programs, Mum2BMoodBooster, and Students Against Depression).</p>
        <p>The evaluation of the included programs showed that, on average, programs scored 85%, indicating that the included web-based programs are generally of good quality. The lowest score was for Students Against Depression (44%) as it did not include information about the developers or the evidence behind the program, privacy notices, terms and conditions. However, Students Against Depression was one of the programs that offered downloadable modules, similar to the CCI programs, and it is currently undergoing evaluation, which may lead to a higher evaluation score once completed. The CCI programs, which scored third to last but are highly regarded by clinicians, included a privacy notice and terms and conditions, and their scores ranged between 69% and 75%. The highest scores were given to the 4 programs by MindSpot, which could only be evaluated against 77% (13/17) of the items. These programs could not be evaluated on more of the items because of restrictions on accessing the program, which may have resulted in higher scores.</p>
        <p>Almost all programs reported that they were based on CBT, either with or without other therapeutic approaches. Only 1 program, ifarmwell, was based on ACT. Although traditional CBT focuses on challenging unhelpful thoughts, ACT focuses on defusing from and accepting them and finding value-consistent ways of living despite the circumstances to build <italic>psychological flexibility</italic> [<xref ref-type="bibr" rid="ref152">152</xref>]. A recent international systematic review and meta-analysis of internet-based ACT programs between 2009 and 2019 [<xref ref-type="bibr" rid="ref153">153</xref>] found 25 efficacy studies in a variety of clinical and nonclinical populations. Overall, the pooled results showed a reduction in symptoms of depression and anxiety and an improvement in quality of life and psychological flexibility at postassessment, with results maintained at follow-up assessments. Given this evidence, it is surprising that not more ACT-based web- interventions are available in Australia. However, that review focused on research-driven studies and not publicly available programs; therefore, none of the studies examined by Thompson et al [<xref ref-type="bibr" rid="ref153">153</xref>] overlapped with this review. Similarly, only 1 program was based on DBT, which differs from CBT in that its main focus is on helping people change their behavior patterns instead of changing dysfunctional beliefs [<xref ref-type="bibr" rid="ref154">154</xref>,<xref ref-type="bibr" rid="ref155">155</xref>]. It also focuses on distress tolerance, which is more like ACT than CBT, and includes mindfulness and interpersonal skills training. A review of clinical effectiveness and guidelines showed that DBT is not statistically significantly greater than comparators in reducing depressive and anxiety symptoms [<xref ref-type="bibr" rid="ref156">156</xref>].</p>
        <p>The results of the current review found that 19% (10/52) of programs provided free therapist support, and 21% (11/52) allowed users to link in their existing clinicians. Research examining whether therapist-guided versus self-guided web-based interventions are more, less, or equally effective has produced mixed results. A recent meta-analysis of 21 studies of web-based programs targeting depression found no significant differences in the effectiveness of the programs to prevent depression based on whether they were guided or not [<xref ref-type="bibr" rid="ref31">31</xref>]. In contrast, another meta-analysis of studies reported greater effect sizes for outcomes from interventions for depression and anxiety that were guided compared with effect sizes for those that were not [<xref ref-type="bibr" rid="ref153">153</xref>]. However, these differences may be because of the type of therapy given, as the former was based on CBT and the latter on ACT. In addition, the use of email or SMS text message reminders or messages of encouragement may compensate for the lack of guidance in some programs. Guided interventions are not always practical to implement and may be expensive and hard to sustain and limit the accessibility of the program. Therefore, future research should continue to examine the impact of incorporating, or not incorporating, these program components and alternatives.</p>
        <p>This review found that roughly half of the programs were structured or tunneled; a further 22 programs provided a recommended structure (but did not require that the user follow this), and 3 programs were unstructured, allowing the user choice in how and when they completed different modules. Research evidence is inconclusive on the manner in which web-based materials are best organized [<xref ref-type="bibr" rid="ref157">157</xref>]. A recent systematic review found inconclusive evidence linking website structure and behavioral or health outcomes [<xref ref-type="bibr" rid="ref158">158</xref>]. They reported that the number of peer-reviewed studies that manipulated website structure to examine its effects on outcome measures was too few to enable conclusive comments to be made. Other studies have provided evidence that allowing unstructured use of websites may increase engagement with the website; however, this may or may not translate into behavior change [<xref ref-type="bibr" rid="ref159">159</xref>]. Therefore, more empirical evidence is required.</p>
        <p>Most resources were designed for adults generally, although a few included programs were designed for specific populations such as farmers, tertiary students, and expectant or new mothers. There were no programs identified in our searches that were designed for hard-to-reach groups such as culturally and linguistically diverse populations or men, and there was only 1 for people from an Aboriginal or Torres Strait Islander cultural background. Web-based interventions provide a useful avenue for administering targeted mental health support to populations who may face barriers to accessing traditional services for cultural reasons. These results highlight the need for more research and development of programs that meet the needs of these at-risk and underserved groups.</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>The use of a scoring system to evaluate and compare programs was based on a framework for evaluating internet-based interventions [<xref ref-type="bibr" rid="ref40">40</xref>], as adapted in subsequent research [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>]. This is a useful tool for comparisons across programs and between this research and past studies. However, items may not reflect the overall true value of a program to a particular consumer, with many elements of the program not being included in this scale and not necessarily being quantifiable as a yes or no item. Future research could extend this by examining how consumers and practitioners select an appropriate resource and the factors that they consider to be important in this choice. In addition, although we evaluated the usability of the programs, no completion rates of the included studies were investigated. Future studies should consider examining the completion rate of programs, as program attrition and nonuse attrition are persistent problems with digital interventions [<xref ref-type="bibr" rid="ref160">160</xref>,<xref ref-type="bibr" rid="ref161">161</xref>].</p>
        <p>At the time of the literature search, there were no national standards for website developers and users to refer to when considering the selection of Australian web-based interventions for mental health. However, on November 30, 2020, the Australian Government released the National Safety and Quality Digital Mental Health Standards for health care providers to refer to when selecting digital media (including web-based programs) for the delivery of high-quality mental health care and suicide prevention (counseling or peer-based support) [<xref ref-type="bibr" rid="ref162">162</xref>]. The purpose of the National Safety and Quality Digital Mental-Health Standards is to provide consumers and practitioners with information on which to base their selection of trustworthy resources and guide resource developers by providing quality standards. Familiarity and use of the standards, along with the findings from the present research, may help GPs and consumers select the most suitable web-based program for their needs. Although standards are now publicly available, an independent assessment tool to identify where a digital mental health service is meeting the standards or where it can improve is currently being developed and will not be available until late 2021. Similar reviews of this type in the future should include information on whether interventions have met these standards and whether this is a self- or independent assessment.</p>
      </sec>
      <sec>
        <title>Comparison With Prior Work</title>
        <p>Overall, of the 52 programs, 9 (17%) addressed depression, 15 (29%) addressed anxiety, 13 (25%) addressed general mental well-being, and 13 (25%) addressed multiple issues. This is substantially lower than the 32 programs for depression and the 34 programs for anxiety identified by Renton et al [<xref ref-type="bibr" rid="ref15">15</xref>] and Ashford et al [<xref ref-type="bibr" rid="ref16">16</xref>], respectively. In part, this is because of the restriction of the current review to programs that were (1) free and (2) accessible to Australians, which excluded several currently available international programs such as Beating the Blues or Deprexis, which offer interventions for a fee or are not available to Australians. In addition, the results may highlight the difficulties consumers face in finding suitable programs through search engines [<xref ref-type="bibr" rid="ref163">163</xref>]. Search engine results were based on the Australian version of Google; however, these results are likely to change over time, as do programs, and the same search conducted at a later date may yield different results. Our search terms were intentionally broad, and we did not require the terms to be used in conjunction with terms describing <italic>therapy</italic> or <italic>self-help.</italic> The purpose of broadening the search in this way was to mirror the type of search that a consumer is likely to perform (focused on the issue and not the intervention type).</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>A total of 52 web-based programs and web-based programs with downloadable worksheets or resources programs are currently freely available to help Australians with the management of depression, anxiety, suicidal ideation, or general mental well-being. Careful attention is needed by clinicians and consumers to determine whether the interventions they refer to, or access, are evidence-based and considered acceptable by other users, given the varied levels of acceptability and impact. This review complements existing resources by providing website summaries and a clear comparison of website features to inform clinicians and consumers and assist in the selection of the most suitable program for the individual. It also identified important gaps in the availability of free web-based interventions in Australia (eg, for culturally and linguistically diverse populations and based on ACT), which may inform future research and program development initiatives.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Google search results.</p>
        <media xlink:href="mental_v9i2e31018_app1.xlsx" xlink:title="XLSX File  (Microsoft Excel File), 18 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Program developers and website links.</p>
        <media xlink:href="mental_v9i2e31018_app2.docx" xlink:title="DOCX File , 20 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Program evaluation scores.</p>
        <media xlink:href="mental_v9i2e31018_app3.xlsx" xlink:title="XLSX File  (Microsoft Excel File), 16 KB"/>
      </supplementary-material>
      <supplementary-material id="app4">
        <label>Multimedia Appendix 4</label>
        <p>Types of research evaluations of eligible programs and summary of evidence.</p>
        <media xlink:href="mental_v9i2e31018_app4.docx" xlink:title="DOCX File , 35 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">ACT</term>
          <def>
            <p>acceptance and commitment therapy</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CBT</term>
          <def>
            <p>cognitive behavioral therapy</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">CCI</term>
          <def>
            <p>Centre for Clinical Interventions</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">DBT</term>
          <def>
            <p>dialectical behavior therapy</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">eMHPrac</term>
          <def>
            <p>e-Mental Health in Practice</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">GP</term>
          <def>
            <p>general practitioner</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">LGBQ</term>
          <def>
            <p>lesbian, gay, bisexual, and queer</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">PRISMA-ScR</term>
          <def>
            <p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb9">RCT</term>
          <def>
            <p>randomized controlled trial</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>The authors would like to acknowledge the program authors who generously gave their time to respond to queries and provided access to their websites. This project was funded by a RACGP Foundation/ANEDGP Innovation Grant 2020 (ANEDGP2020-04).</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>This project was overseen by GS and KG. GS and KG devised the concept for the review, with input from CH, NJ, DT, and MS. The grant was applied for and won by GS, CH, KG, NJ, and DT. GS wrote the initial draft. GS, SvdK, and SL conducted the searches. GS, SvdK, SL, and DHB conducted the rapid review. All authors contributed to the final manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>The authors KG, DT, and GS are involved in the development and evaluation of ifarmwell (a web-based intervention described in this paper).</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="web">
          <article-title>Australia’s health 2018</article-title>
          <source>Australian Institute of Health and Welfare</source>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.aihw.gov.au/getmedia/7c42913d-295f-4bc9-9c24-4e44eff4a04a/aihw-aus-221.pdf">https://www.aihw.gov.au/getmedia/7c42913d-295f-4bc9-9c24-4e44eff4a04a/aihw-aus-221.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="web">
          <article-title>Deaths in Australia</article-title>
          <source>Australian Institute of Health and Welfare</source>
          <year>2021</year>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.aihw.gov.au/reports/phe/229/deaths/deaths-in-australia/contents/life-expectancy">https://www.aihw.gov.au/reports/phe/229/deaths/deaths-in-australia/contents/life-expectancy</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Slade</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Teesson</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Whiteford</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Burgess</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Pirkis</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Saw</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <source>The Mental Health of Australians 2: Report on the 2007 National Survey of Mental Health and Wellbeing</source>
          <year>2009</year>
          <publisher-loc>Canberra</publisher-loc>
          <publisher-name>Department of Health and Ageing</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Luoma</surname>
              <given-names>JB</given-names>
            </name>
            <name name-style="western">
              <surname>Martin</surname>
              <given-names>CE</given-names>
            </name>
            <name name-style="western">
              <surname>Pearson</surname>
              <given-names>JL</given-names>
            </name>
          </person-group>
          <article-title>Contact with mental health and primary care providers before suicide: a review of the evidence</article-title>
          <source>Am J Psychiatry</source>
          <year>2002</year>
          <month>06</month>
          <volume>159</volume>
          <issue>6</issue>
          <fpage>909</fpage>
          <lpage>16</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/12042175"/>
          </comment>
          <pub-id pub-id-type="doi">10.1176/appi.ajp.159.6.909</pub-id>
          <pub-id pub-id-type="medline">12042175</pub-id>
          <pub-id pub-id-type="pmcid">PMC5072576</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bagayogo</surname>
              <given-names>IP</given-names>
            </name>
            <name name-style="western">
              <surname>Turcios-Wiswe</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Taku</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Peccoralo</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Katz</surname>
              <given-names>CL</given-names>
            </name>
          </person-group>
          <article-title>Providing mental health services in the primary care setting: the experiences and perceptions of general practitioners at a New York City clinic</article-title>
          <source>Psychiatr Q</source>
          <year>2018</year>
          <month>12</month>
          <volume>89</volume>
          <issue>4</issue>
          <fpage>897</fpage>
          <lpage>908</lpage>
          <pub-id pub-id-type="doi">10.1007/s11126-018-9587-2</pub-id>
          <pub-id pub-id-type="medline">29968148</pub-id>
          <pub-id pub-id-type="pii">10.1007/s11126-018-9587-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wong</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Harrison</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Britt</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Henderson</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Patient use of the internet for health information</article-title>
          <source>Aust Fam Physician</source>
          <year>2014</year>
          <month>12</month>
          <volume>43</volume>
          <issue>12</issue>
          <fpage>875</fpage>
          <lpage>7</lpage>
          <pub-id pub-id-type="medline">25705739</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="web">
          <article-title>Household use of information technology</article-title>
          <source>Australian Bureau of Statistics</source>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.abs.gov.au/statistics/industry/technology-and-innovation/household-use-information-technology/latest-release">https://www.abs.gov.au/statistics/industry/technology-and-innovation/household-use-information-technology/latest-release</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Barak</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Grohol</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>Current and future trends in internet-supported mental health interventions</article-title>
          <source>J Technol Human Services</source>
          <year>2011</year>
          <month>07</month>
          <volume>29</volume>
          <issue>3</issue>
          <fpage>155</fpage>
          <lpage>96</lpage>
          <pub-id pub-id-type="doi">10.1080/15228835.2011.616939</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hull</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Fennell</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Vallury</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Jones</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Dollman</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>A comparison of barriers to mental health support-seeking among farming and non-farming adults in rural South Australia</article-title>
          <source>Aust J Rural Health</source>
          <year>2017</year>
          <month>12</month>
          <volume>25</volume>
          <issue>6</issue>
          <fpage>347</fpage>
          <lpage>53</lpage>
          <pub-id pub-id-type="doi">10.1111/ajr.12352</pub-id>
          <pub-id pub-id-type="medline">28618088</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McDermott</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Dozois</surname>
              <given-names>DJ</given-names>
            </name>
          </person-group>
          <article-title>A randomized controlled trial of internet-delivered CBT and attention bias modification for early intervention of depression</article-title>
          <source>J Experimental Psychopathol</source>
          <year>2019</year>
          <month>04</month>
          <day>18</day>
          <volume>10</volume>
          <issue>2</issue>
          <fpage>204380871984250</fpage>
          <pub-id pub-id-type="doi">10.1177/2043808719842502</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Maher</surname>
              <given-names>AR</given-names>
            </name>
            <name name-style="western">
              <surname>Apaydin</surname>
              <given-names>EA</given-names>
            </name>
            <name name-style="western">
              <surname>Raaen</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Motala</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Baxi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Hempel</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>The use of technology in the clinical care of anxiety: an evidence map</article-title>
          <source>Psychiatr Serv</source>
          <year>2021</year>
          <month>02</month>
          <day>01</day>
          <volume>72</volume>
          <issue>2</issue>
          <fpage>195</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1176/appi.ps.202000178</pub-id>
          <pub-id pub-id-type="medline">33291972</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Powell</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Atherton</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Yang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Davoudianfar</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Hellsing</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Martin</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Mollison</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Shanyinde</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Yu</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness and cost-effectiveness of a self-guided internet intervention for social anxiety symptoms in a general population sample: randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2020</year>
          <month>01</month>
          <day>10</day>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>e16804</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2020/1/e16804/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/16804</pub-id>
          <pub-id pub-id-type="medline">31821151</pub-id>
          <pub-id pub-id-type="pii">v22i1e16804</pub-id>
          <pub-id pub-id-type="pmcid">PMC6996778</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kiropoulos</surname>
              <given-names>LA</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Blashki</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Effects of a multilingual information website intervention on the levels of depression literacy and depression-related stigma in Greek-born and Italian-born immigrants living in Australia: a randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2011</year>
          <month>04</month>
          <day>19</day>
          <volume>13</volume>
          <issue>2</issue>
          <fpage>e34</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2011/2/e34/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.1527</pub-id>
          <pub-id pub-id-type="medline">21504872</pub-id>
          <pub-id pub-id-type="pii">v13i2e34</pub-id>
          <pub-id pub-id-type="pmcid">PMC3221382</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Jorm</surname>
              <given-names>AF</given-names>
            </name>
            <name name-style="western">
              <surname>Korten</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Jacomb</surname>
              <given-names>PA</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Rodgers</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Pollitt</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>"Mental health literacy": a survey of the public's ability to recognise mental disorders and their beliefs about the effectiveness of treatment</article-title>
          <source>Med J Aust</source>
          <year>1997</year>
          <month>02</month>
          <day>17</day>
          <volume>166</volume>
          <issue>4</issue>
          <fpage>182</fpage>
          <lpage>6</lpage>
          <pub-id pub-id-type="doi">10.5694/j.1326-5377.1997.tb140071.x</pub-id>
          <pub-id pub-id-type="medline">9066546</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Renton</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Tang</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Ennis</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Cusimano</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Bhalerao</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Schweizer</surname>
              <given-names>TA</given-names>
            </name>
            <name name-style="western">
              <surname>Topolovec-Vranic</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Web-based intervention programs for depression: a scoping review and evaluation</article-title>
          <source>J Med Internet Res</source>
          <year>2014</year>
          <month>09</month>
          <day>23</day>
          <volume>16</volume>
          <issue>9</issue>
          <fpage>e209</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2014/9/e209/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.3147</pub-id>
          <pub-id pub-id-type="medline">25249003</pub-id>
          <pub-id pub-id-type="pii">v16i9e209</pub-id>
          <pub-id pub-id-type="pmcid">PMC4211022</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ashford</surname>
              <given-names>MT</given-names>
            </name>
            <name name-style="western">
              <surname>Olander</surname>
              <given-names>EK</given-names>
            </name>
            <name name-style="western">
              <surname>Ayers</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Finding web-based anxiety interventions on the world wide web: a scoping review</article-title>
          <source>JMIR Ment Health</source>
          <year>2016</year>
          <month>06</month>
          <day>01</day>
          <volume>3</volume>
          <issue>2</issue>
          <fpage>e14</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2016/2/e14/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mental.5349</pub-id>
          <pub-id pub-id-type="medline">27251763</pub-id>
          <pub-id pub-id-type="pii">v3i2e14</pub-id>
          <pub-id pub-id-type="pmcid">PMC4936762</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Jorm</surname>
              <given-names>AF</given-names>
            </name>
            <name name-style="western">
              <surname>Evans</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Groves</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Effect of web-based depression literacy and cognitive-behavioural therapy interventions on stigmatising attitudes to depression: randomised controlled trial</article-title>
          <source>Br J Psychiatry</source>
          <year>2004</year>
          <month>10</month>
          <volume>185</volume>
          <fpage>342</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1192/bjp.185.4.342</pub-id>
          <pub-id pub-id-type="medline">15458995</pub-id>
          <pub-id pub-id-type="pii">S0007125000165547</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kennedy</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Brumby</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>Versace</surname>
              <given-names>VL</given-names>
            </name>
            <name name-style="western">
              <surname>Brumby-Rendell</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>The ripple effect: a digital intervention to reduce suicide stigma among farming men</article-title>
          <source>BMC Public Health</source>
          <year>2020</year>
          <month>05</month>
          <day>29</day>
          <volume>20</volume>
          <issue>1</issue>
          <fpage>813</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-020-08954-5"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12889-020-08954-5</pub-id>
          <pub-id pub-id-type="medline">32471501</pub-id>
          <pub-id pub-id-type="pii">10.1186/s12889-020-08954-5</pub-id>
          <pub-id pub-id-type="pmcid">PMC7260777</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kirschner</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Goetzl</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Curtin</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Mental health stigma among college students: test of an interactive online intervention</article-title>
          <source>J Am Coll Health</source>
          <year>2020</year>
          <month>10</month>
          <day>13</day>
          <fpage>1</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1080/07448481.2020.1826492</pub-id>
          <pub-id pub-id-type="medline">33048656</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gunn</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Barrett</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hughes-Barton</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Turnbull</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Short</surname>
              <given-names>CE</given-names>
            </name>
            <name name-style="western">
              <surname>Brumby</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Skaczkowski</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Dollman</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>What farmers want from mental health and wellbeing-focused websites and online interventions</article-title>
          <source>J Rur Stud</source>
          <year>2021</year>
          <month>08</month>
          <volume>86</volume>
          <fpage>298</fpage>
          <lpage>308</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jrurstud.2021.06.016</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>March</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Spence</surname>
              <given-names>SH</given-names>
            </name>
            <name name-style="western">
              <surname>Donovan</surname>
              <given-names>CL</given-names>
            </name>
            <name name-style="western">
              <surname>Kenardy</surname>
              <given-names>JA</given-names>
            </name>
          </person-group>
          <article-title>Large-scale dissemination of internet-based cognitive behavioral therapy for youth anxiety: feasibility and acceptability study</article-title>
          <source>J Med Internet Res</source>
          <year>2018</year>
          <month>07</month>
          <day>04</day>
          <volume>20</volume>
          <issue>7</issue>
          <fpage>e234</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2018/7/e234/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.9211</pub-id>
          <pub-id pub-id-type="medline">29973338</pub-id>
          <pub-id pub-id-type="pii">v20i7e234</pub-id>
          <pub-id pub-id-type="pmcid">PMC6053603</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Zou</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Hunt</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Culturally attuned internet treatment for depression amongst Chinese Australians: a randomised controlled trial</article-title>
          <source>J Affect Disord</source>
          <year>2012</year>
          <month>02</month>
          <volume>136</volume>
          <issue>3</issue>
          <fpage>459</fpage>
          <lpage>68</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2011.11.003</pub-id>
          <pub-id pub-id-type="medline">22177742</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(11)00716-6</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kayrouz</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Karin</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>A pilot study of a clinician-guided internet-delivered cognitive behavioural therapy for anxiety and depression among Arabs in Australia, presented in both English and Arabic languages</article-title>
          <source>Internet Interv</source>
          <year>2016</year>
          <month>09</month>
          <volume>5</volume>
          <fpage>5</fpage>
          <lpage>11</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(16)30015-X"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2016.06.002</pub-id>
          <pub-id pub-id-type="medline">30135801</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(16)30015-X</pub-id>
          <pub-id pub-id-type="pmcid">PMC6096205</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Johnson</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Singh</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Wilkes</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Brkic</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Gupta</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Jones</surname>
              <given-names>MP</given-names>
            </name>
            <name name-style="western">
              <surname>Bailey</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Dudeney</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Examining an internet-delivered intervention for anxiety and depression when delivered as a part of routine care for university students: a phase IV trial</article-title>
          <source>J Affect Disord</source>
          <year>2019</year>
          <month>09</month>
          <day>01</day>
          <volume>256</volume>
          <fpage>567</fpage>
          <lpage>77</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0165-0327(19)31139-5"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.jad.2019.06.044</pub-id>
          <pub-id pub-id-type="medline">31280082</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(19)31139-5</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Anderson</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>O'Moore</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Faraj</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Proudfoot</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Stepped care mental health service in Australian primary care: codesign and feasibility study</article-title>
          <source>Aust. Health Review</source>
          <year>2020</year>
          <volume>44</volume>
          <issue>6</issue>
          <fpage>873</fpage>
          <pub-id pub-id-type="doi">10.1071/ah19078</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Subotic-Kerry</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>King</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>O'Moore</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Achilles</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>O'Dea</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>General practitioners' attitudes toward a web-based mental health service for adolescents: implications for service design and delivery</article-title>
          <source>JMIR Hum Factors</source>
          <year>2018</year>
          <month>03</month>
          <day>23</day>
          <volume>5</volume>
          <issue>1</issue>
          <fpage>e12</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://humanfactors.jmir.org/2018/1/e12/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/humanfactors.8913</pub-id>
          <pub-id pub-id-type="medline">29572203</pub-id>
          <pub-id pub-id-type="pii">v5i1e12</pub-id>
          <pub-id pub-id-type="pmcid">PMC5889492</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Harrer</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Adam</surname>
              <given-names>SH</given-names>
            </name>
            <name name-style="western">
              <surname>Baumeister</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Karyotaki</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Auerbach</surname>
              <given-names>RP</given-names>
            </name>
            <name name-style="western">
              <surname>Kessler</surname>
              <given-names>RC</given-names>
            </name>
            <name name-style="western">
              <surname>Bruffaerts</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Berking</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Ebert</surname>
              <given-names>DD</given-names>
            </name>
          </person-group>
          <article-title>Internet interventions for mental health in university students: a systematic review and meta-analysis</article-title>
          <source>Int J Methods Psychiatr Res</source>
          <year>2019</year>
          <month>06</month>
          <volume>28</volume>
          <issue>2</issue>
          <fpage>e1759</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/30585363"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/mpr.1759</pub-id>
          <pub-id pub-id-type="medline">30585363</pub-id>
          <pub-id pub-id-type="pmcid">PMC6877279</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="web">
          <article-title>A guide to digital mental health resources</article-title>
          <source>E-Mental Health in Practice</source>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.emhprac.org.au/resource/a-guide-to-digital-mental-health-resources/">https://www.emhprac.org.au/resource/a-guide-to-digital-mental-health-resources/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Köhnen</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Dreier</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Seeralan</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Kriston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Härter</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Baumeister</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Liebherz</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Evidence on technology-based psychological interventions in diagnosed depression: systematic review</article-title>
          <source>JMIR Ment Health</source>
          <year>2021</year>
          <month>02</month>
          <day>10</day>
          <volume>8</volume>
          <issue>2</issue>
          <fpage>e21700</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2021/2/e21700/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/21700</pub-id>
          <pub-id pub-id-type="medline">33565981</pub-id>
          <pub-id pub-id-type="pii">v8i2e21700</pub-id>
          <pub-id pub-id-type="pmcid">PMC7904404</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tokgöz</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Hrynyschyn</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Hafner</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Schönfeld</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Dockweiler</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Digital health interventions in prevention, relapse, and therapy of mild and moderate depression: scoping review</article-title>
          <source>JMIR Ment Health</source>
          <year>2021</year>
          <month>04</month>
          <day>16</day>
          <volume>8</volume>
          <issue>4</issue>
          <fpage>e26268</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2021/4/e26268/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/26268</pub-id>
          <pub-id pub-id-type="medline">33861201</pub-id>
          <pub-id pub-id-type="pii">v8i4e26268</pub-id>
          <pub-id pub-id-type="pmcid">PMC8087966</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rigabert</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Motrico</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Moreno-Peral</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Resurrección</surname>
              <given-names>DM</given-names>
            </name>
            <name name-style="western">
              <surname>Conejo-Cerón</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Martín-Gómez</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>López-Del-Hoyo</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Bellón</surname>
              <given-names>JÁ</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness of online psychological and psychoeducational interventions to prevent depression: systematic review and meta-analysis of randomized controlled trials</article-title>
          <source>Clin Psychol Rev</source>
          <year>2020</year>
          <month>12</month>
          <volume>82</volume>
          <fpage>101931</fpage>
          <pub-id pub-id-type="doi">10.1016/j.cpr.2020.101931</pub-id>
          <pub-id pub-id-type="medline">33137611</pub-id>
          <pub-id pub-id-type="pii">S0272-7358(20)30119-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christ</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Schouten</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Blankers</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>van Schaik</surname>
              <given-names>DJ</given-names>
            </name>
            <name name-style="western">
              <surname>Beekman</surname>
              <given-names>AT</given-names>
            </name>
            <name name-style="western">
              <surname>Wisman</surname>
              <given-names>MA</given-names>
            </name>
            <name name-style="western">
              <surname>Stikkelbroek</surname>
              <given-names>YA</given-names>
            </name>
            <name name-style="western">
              <surname>Dekker</surname>
              <given-names>JJ</given-names>
            </name>
          </person-group>
          <article-title>Internet and computer-based cognitive behavioral therapy for anxiety and depression in adolescents and young adults: systematic review and meta-analysis</article-title>
          <source>J Med Internet Res</source>
          <year>2020</year>
          <month>09</month>
          <day>25</day>
          <volume>22</volume>
          <issue>9</issue>
          <fpage>e17831</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2020/9/e17831/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/17831</pub-id>
          <pub-id pub-id-type="medline">32673212</pub-id>
          <pub-id pub-id-type="pii">v22i9e17831</pub-id>
          <pub-id pub-id-type="pmcid">PMC7547394</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lehtimaki</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Martic</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Wahl</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Foster</surname>
              <given-names>KT</given-names>
            </name>
            <name name-style="western">
              <surname>Schwalbe</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Evidence on digital mental health interventions for adolescents and young people: systematic overview</article-title>
          <source>JMIR Ment Health</source>
          <year>2021</year>
          <month>04</month>
          <day>29</day>
          <volume>8</volume>
          <issue>4</issue>
          <fpage>e25847</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2021/4/e25847/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/25847</pub-id>
          <pub-id pub-id-type="medline">33913817</pub-id>
          <pub-id pub-id-type="pii">v8i4e25847</pub-id>
          <pub-id pub-id-type="pmcid">PMC8120421</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Peters</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Marnie</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Tricco</surname>
              <given-names>AC</given-names>
            </name>
            <name name-style="western">
              <surname>Pollock</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Munn</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>Alexander</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>McInerney</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Godfrey</surname>
              <given-names>CM</given-names>
            </name>
            <name name-style="western">
              <surname>Khalil</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Updated methodological guidance for the conduct of scoping reviews</article-title>
          <source>JBI Evid Synth</source>
          <year>2020</year>
          <month>10</month>
          <volume>18</volume>
          <issue>10</issue>
          <fpage>2119</fpage>
          <lpage>26</lpage>
          <pub-id pub-id-type="doi">10.11124/JBIES-20-00167</pub-id>
          <pub-id pub-id-type="medline">33038124</pub-id>
          <pub-id pub-id-type="pii">02174543-202010000-00004</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Tricco</surname>
              <given-names>AC</given-names>
            </name>
            <name name-style="western">
              <surname>Lillie</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Zarin</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>O'Brien</surname>
              <given-names>KK</given-names>
            </name>
            <name name-style="western">
              <surname>Colquhoun</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Levac</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Moher</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Peters</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Horsley</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Weeks</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Hempel</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Akl</surname>
              <given-names>EA</given-names>
            </name>
            <name name-style="western">
              <surname>Chang</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>McGowan</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Stewart</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Hartling</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Aldcroft</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Wilson</surname>
              <given-names>MG</given-names>
            </name>
            <name name-style="western">
              <surname>Garritty</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Lewin</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Godfrey</surname>
              <given-names>CM</given-names>
            </name>
            <name name-style="western">
              <surname>Macdonald</surname>
              <given-names>MT</given-names>
            </name>
            <name name-style="western">
              <surname>Langlois</surname>
              <given-names>EV</given-names>
            </name>
            <name name-style="western">
              <surname>Soares-Weiser</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Moriarty</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Clifford</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Tunçalp</surname>
              <given-names>Ö</given-names>
            </name>
            <name name-style="western">
              <surname>Straus</surname>
              <given-names>SE</given-names>
            </name>
          </person-group>
          <article-title>PRISMA Extension for Scoping Reviews (PRISMA-ScR): checklist and explanation</article-title>
          <source>Ann Intern Med</source>
          <year>2018</year>
          <month>10</month>
          <day>02</day>
          <volume>169</volume>
          <issue>7</issue>
          <fpage>467</fpage>
          <lpage>73</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.acpjournals.org/doi/abs/10.7326/M18-0850?url_ver=Z39.88-2003&#38;rfr_id=ori:rid:crossref.org&#38;rfr_dat=cr_pub%3dpubmed"/>
          </comment>
          <pub-id pub-id-type="doi">10.7326/M18-0850</pub-id>
          <pub-id pub-id-type="medline">30178033</pub-id>
          <pub-id pub-id-type="pii">2700389</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Skaczkowski</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>van der Kruk</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Gunn</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Howell</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Jensen</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Turnbull</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Scoping review to identify web-based resources for depression, anxiety, suicidal ideation and general wellbeing</article-title>
          <source>Open Science Framework</source>
          <year>2020</year>
          <access-date>2022-01-11</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://osf.io/rg9fj">https://osf.io/rg9fj</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="web">
          <article-title>Beacon</article-title>
          <source>Beacon 2.0</source>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://beacon.anu.edu.au/">https://beacon.anu.edu.au/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="web">
          <article-title>Head to health</article-title>
          <source>Australian Government Department of Health</source>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://headtohealth.gov.au/">https://headtohealth.gov.au/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="web">
          <article-title>Resource library</article-title>
          <source>E-Mental Health in Practice</source>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.emhprac.org.au/">https://www.emhprac.org.au/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Proudfoot</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Barak</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Carlbring</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Lange</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Ritterband</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Establishing guidelines for executing and reporting internet intervention research</article-title>
          <source>Cogn Behav Ther</source>
          <year>2011</year>
          <volume>40</volume>
          <issue>2</issue>
          <fpage>82</fpage>
          <lpage>97</lpage>
          <pub-id pub-id-type="doi">10.1080/16506073.2011.573807</pub-id>
          <pub-id pub-id-type="medline">25155812</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Merlin</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Weston</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Tooher</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Middleton</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Salisbury</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Coleman</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>NHMRC levels of evidence and grades for recommendations for developers of guidelines</article-title>
          <source>National Health and Medical Research Council</source>
          <year>2009</year>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.nhmrc.gov.au/sites/default/files/images/NHMRC%20Levels%20and%20Grades%20(2009).pdf">https://www.nhmrc.gov.au/sites/default/files/images/NHMRC%20Levels%20and%20Grades%20(2009).pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Melvin</surname>
              <given-names>GA</given-names>
            </name>
            <name name-style="western">
              <surname>Gresham</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Beaton</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Coles</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Tonge</surname>
              <given-names>BJ</given-names>
            </name>
            <name name-style="western">
              <surname>Gordon</surname>
              <given-names>MS</given-names>
            </name>
            <name name-style="western">
              <surname>Stanley</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Evaluating the feasibility and effectiveness of an Australian safety planning smartphone application: a pilot study within a tertiary mental health service</article-title>
          <source>Suicide Life Threat Behav</source>
          <year>2019</year>
          <month>06</month>
          <volume>49</volume>
          <issue>3</issue>
          <fpage>846</fpage>
          <lpage>58</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/29999193"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/sltb.12490</pub-id>
          <pub-id pub-id-type="medline">29999193</pub-id>
          <pub-id pub-id-type="pmcid">PMC6618059</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Draper</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Rees</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Nathan</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Internet-based self-management of generalised anxiety disorder: a preliminary study</article-title>
          <source>Behav Change</source>
          <year>2012</year>
          <month>02</month>
          <day>22</day>
          <volume>25</volume>
          <issue>4</issue>
          <fpage>229</fpage>
          <lpage>44</lpage>
          <pub-id pub-id-type="doi">10.1375/bech.25.4.229</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Batterham</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Kalia Hehir</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Kenardy</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Gosling</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Prevention of generalized anxiety disorder using a web intervention, iChill: randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2014</year>
          <month>09</month>
          <day>02</day>
          <volume>16</volume>
          <issue>9</issue>
          <fpage>e199</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2014/9/e199/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.3507</pub-id>
          <pub-id pub-id-type="medline">25270886</pub-id>
          <pub-id pub-id-type="pii">v16i9e199</pub-id>
          <pub-id pub-id-type="pmcid">PMC4211086</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Batterham</surname>
              <given-names>PJ</given-names>
            </name>
            <name name-style="western">
              <surname>O'Dea</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Guastella</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Eagleson</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Kalia Hehir</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Kenardy</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Hickie</surname>
              <given-names>I</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of an online e-health application compared to attention placebo or Sertraline in the treatment of Generalised Anxiety Disorder</article-title>
          <source>Internet Interventions</source>
          <year>2014</year>
          <month>10</month>
          <volume>1</volume>
          <issue>4</issue>
          <fpage>169</fpage>
          <lpage>74</lpage>
          <pub-id pub-id-type="doi">10.1016/j.invent.2014.08.002</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Donker</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>van Straten</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
          </person-group>
          <article-title>Internet-delivered interpersonal psychotherapy versus internet-delivered cognitive behavioral therapy for adults with depressive symptoms: randomized controlled noninferiority trial</article-title>
          <source>J Med Internet Res</source>
          <year>2013</year>
          <month>05</month>
          <day>13</day>
          <volume>15</volume>
          <issue>5</issue>
          <fpage>e82</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2013/5/e82/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.2307</pub-id>
          <pub-id pub-id-type="medline">23669884</pub-id>
          <pub-id pub-id-type="pii">v15i5e82</pub-id>
          <pub-id pub-id-type="pmcid">PMC3668608</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Crisp</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>An online intervention for reducing depressive symptoms: secondary benefits for self-esteem, empowerment and quality of life</article-title>
          <source>Psychiatry Res</source>
          <year>2014</year>
          <month>04</month>
          <day>30</day>
          <volume>216</volume>
          <issue>1</issue>
          <fpage>60</fpage>
          <lpage>6</lpage>
          <pub-id pub-id-type="doi">10.1016/j.psychres.2014.01.041</pub-id>
          <pub-id pub-id-type="medline">24534125</pub-id>
          <pub-id pub-id-type="pii">S0165-1781(14)00082-1</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Glozier</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Naismith</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Cockayne</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Donkin</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Neal</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hickie</surname>
              <given-names>I</given-names>
            </name>
          </person-group>
          <article-title>Internet-delivered cognitive behavioural therapy for adults with mild to moderate depression and high cardiovascular disease risks: a randomised attention-controlled trial</article-title>
          <source>PLoS One</source>
          <year>2013</year>
          <volume>8</volume>
          <issue>3</issue>
          <fpage>e59139</fpage>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0059139</pub-id>
          <pub-id pub-id-type="medline">23555624</pub-id>
          <pub-id pub-id-type="pii">PONE-D-12-36365</pub-id>
          <pub-id pub-id-type="pmcid">PMC3608590</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Donkin</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Hickie</surname>
              <given-names>IB</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Naismith</surname>
              <given-names>SL</given-names>
            </name>
            <name name-style="western">
              <surname>Neal</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Cockayne</surname>
              <given-names>NL</given-names>
            </name>
            <name name-style="western">
              <surname>Glozier</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Rethinking the dose-response relationship between usage and outcome in an online intervention for depression: randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2013</year>
          <month>10</month>
          <day>17</day>
          <volume>15</volume>
          <issue>10</issue>
          <fpage>e231</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2013/10/e231/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.2771</pub-id>
          <pub-id pub-id-type="medline">24135213</pub-id>
          <pub-id pub-id-type="pii">v15i10e231</pub-id>
          <pub-id pub-id-type="pmcid">PMC3806549</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Donker</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Batterham</surname>
              <given-names>PJ</given-names>
            </name>
            <name name-style="western">
              <surname>Warmerdam</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Predictors and moderators of response to internet-delivered Interpersonal Psychotherapy and Cognitive Behavior Therapy for depression</article-title>
          <source>J Affect Disord</source>
          <year>2013</year>
          <month>10</month>
          <volume>151</volume>
          <issue>1</issue>
          <fpage>343</fpage>
          <lpage>51</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2013.06.020</pub-id>
          <pub-id pub-id-type="medline">23953024</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(13)00500-4</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bowler</surname>
              <given-names>JO</given-names>
            </name>
            <name name-style="western">
              <surname>Mackintosh</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Dunn</surname>
              <given-names>BD</given-names>
            </name>
            <name name-style="western">
              <surname>Mathews</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Dalgleish</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Hoppitt</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>A comparison of cognitive bias modification for interpretation and computerized cognitive behavior therapy: effects on anxiety, depression, attentional control, and interpretive bias</article-title>
          <source>J Consult Clin Psychol</source>
          <year>2012</year>
          <month>12</month>
          <volume>80</volume>
          <issue>6</issue>
          <fpage>1021</fpage>
          <lpage>33</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/22963595"/>
          </comment>
          <pub-id pub-id-type="doi">10.1037/a0029932</pub-id>
          <pub-id pub-id-type="medline">22963595</pub-id>
          <pub-id pub-id-type="pii">2012-24314-001</pub-id>
          <pub-id pub-id-type="pmcid">PMC3516492</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Farvolden</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Denisoff</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Selby</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Bagby</surname>
              <given-names>RM</given-names>
            </name>
            <name name-style="western">
              <surname>Rudy</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Usage and longitudinal effectiveness of a web-based self-help cognitive behavioral therapy program for panic disorder</article-title>
          <source>J Med Internet Res</source>
          <year>2005</year>
          <month>03</month>
          <day>26</day>
          <volume>7</volume>
          <issue>1</issue>
          <fpage>e7</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2005/1/e7/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.7.1.e7</pub-id>
          <pub-id pub-id-type="medline">15829479</pub-id>
          <pub-id pub-id-type="pii">v7e7</pub-id>
          <pub-id pub-id-type="pmcid">PMC1550639</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Cunningham</surname>
              <given-names>JA</given-names>
            </name>
            <name name-style="western">
              <surname>Hodgins</surname>
              <given-names>DC</given-names>
            </name>
            <name name-style="western">
              <surname>Toneatto</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Murphy</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>A randomized controlled trial of a personalized feedback intervention for problem gamblers</article-title>
          <source>PLoS One</source>
          <year>2012</year>
          <volume>7</volume>
          <issue>2</issue>
          <fpage>e31586</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0031586"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0031586</pub-id>
          <pub-id pub-id-type="medline">22348112</pub-id>
          <pub-id pub-id-type="pii">PONE-D-11-20293</pub-id>
          <pub-id pub-id-type="pmcid">PMC3279405</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref54">
        <label>54</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>van Mierlo</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Hyatt</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Ching</surname>
              <given-names>AT</given-names>
            </name>
          </person-group>
          <article-title>Demographic and indication-specific characteristics have limited association with social network engagement: evidence from 24,954 members of four health care support groups</article-title>
          <source>J Med Internet Res</source>
          <year>2017</year>
          <month>02</month>
          <day>17</day>
          <volume>19</volume>
          <issue>2</issue>
          <fpage>e40</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2017/2/e40/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.6330</pub-id>
          <pub-id pub-id-type="medline">28213340</pub-id>
          <pub-id pub-id-type="pii">v19i2e40</pub-id>
          <pub-id pub-id-type="pmcid">PMC5336601</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref55">
        <label>55</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Pittaway</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Cupitt</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Palmer</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Arowobusoye</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Milne</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Holttum</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Pezet</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Patrick</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Comparative, clinical feasibility study of three tools for delivery of cognitive behavioural therapy for mild to moderate depression and anxiety provided on a self-help basis</article-title>
          <source>Ment Health Fam Med</source>
          <year>2009</year>
          <month>09</month>
          <volume>6</volume>
          <issue>3</issue>
          <fpage>145</fpage>
          <lpage>54</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/22477905"/>
          </comment>
          <pub-id pub-id-type="medline">22477905</pub-id>
          <pub-id pub-id-type="pmcid">PMC2838647</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref56">
        <label>56</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Elison</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Ward</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Espie</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Davies</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Dugdale</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Ragan</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Chisnall</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Lidbetter</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Feasibility of a UK community-based, eTherapy mental health service in Greater Manchester: repeated-measures and between-groups study of 'Living Life to the Full Interactive', 'Sleepio' and 'Breaking Free Online' at 'Self Help Services'</article-title>
          <source>BMJ Open</source>
          <year>2017</year>
          <month>07</month>
          <day>20</day>
          <volume>7</volume>
          <issue>7</issue>
          <fpage>e016392</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmjopen.bmj.com/lookup/pmidlookup?view=long&#38;pmid=28729322"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/bmjopen-2017-016392</pub-id>
          <pub-id pub-id-type="medline">28729322</pub-id>
          <pub-id pub-id-type="pii">bmjopen-2017-016392</pub-id>
          <pub-id pub-id-type="pmcid">PMC5541623</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref57">
        <label>57</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hadjistavropoulos</surname>
              <given-names>HD</given-names>
            </name>
            <name name-style="western">
              <surname>Pugh</surname>
              <given-names>NE</given-names>
            </name>
            <name name-style="western">
              <surname>Nugent</surname>
              <given-names>MM</given-names>
            </name>
            <name name-style="western">
              <surname>Hesser</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Ivanov</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Butz</surname>
              <given-names>CG</given-names>
            </name>
            <name name-style="western">
              <surname>Marchildon</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Asmundson</surname>
              <given-names>GJ</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Austin</surname>
              <given-names>DW</given-names>
            </name>
          </person-group>
          <article-title>Therapist-assisted Internet-delivered cognitive behavior therapy for depression and anxiety: translating evidence into clinical practice</article-title>
          <source>J Anxiety Disord</source>
          <year>2014</year>
          <month>12</month>
          <volume>28</volume>
          <issue>8</issue>
          <fpage>884</fpage>
          <lpage>93</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0887-6185(14)00142-X"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2014.09.018</pub-id>
          <pub-id pub-id-type="medline">25445078</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(14)00142-X</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref58">
        <label>58</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hadjistavropoulos</surname>
              <given-names>HD</given-names>
            </name>
            <name name-style="western">
              <surname>Pugh</surname>
              <given-names>NE</given-names>
            </name>
            <name name-style="western">
              <surname>Hesser</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Predicting response to therapist-assisted internet-delivered cognitive behavior therapy for depression or anxiety within an open dissemination trial</article-title>
          <source>Behav Ther</source>
          <year>2016</year>
          <month>03</month>
          <volume>47</volume>
          <issue>2</issue>
          <fpage>155</fpage>
          <lpage>65</lpage>
          <pub-id pub-id-type="doi">10.1016/j.beth.2015.10.006</pub-id>
          <pub-id pub-id-type="medline">26956649</pub-id>
          <pub-id pub-id-type="pii">S0005-7894(15)00116-1</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref59">
        <label>59</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Al-Asadi</surname>
              <given-names>AM</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Meyer</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Posttreatment attrition and its predictors, attrition bias, and treatment efficacy of the anxiety online programs</article-title>
          <source>J Med Internet Res</source>
          <year>2014</year>
          <month>10</month>
          <day>14</day>
          <volume>16</volume>
          <issue>10</issue>
          <fpage>e232</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2014/10/e232/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.3513</pub-id>
          <pub-id pub-id-type="medline">25316533</pub-id>
          <pub-id pub-id-type="pii">v16i10e232</pub-id>
          <pub-id pub-id-type="pmcid">PMC4211028</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref60">
        <label>60</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Meyer</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Austin</surname>
              <given-names>DW</given-names>
            </name>
            <name name-style="western">
              <surname>Kyrios</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Anxiety online: a virtual clinic: preliminary outcomes following completion of five fully automated treatment programs for anxiety disorders and symptoms</article-title>
          <source>J Med Internet Res</source>
          <year>2011</year>
          <month>11</month>
          <day>04</day>
          <volume>13</volume>
          <issue>4</issue>
          <fpage>e89</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2011/4/e89/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.1918</pub-id>
          <pub-id pub-id-type="medline">22057287</pub-id>
          <pub-id pub-id-type="pii">v13i4e89</pub-id>
          <pub-id pub-id-type="pmcid">PMC3222205</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref61">
        <label>61</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Schofield</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Nielssen</surname>
              <given-names>O</given-names>
            </name>
          </person-group>
          <article-title>A comparison of Indigenous and non-Indigenous users of MindSpot: an Australian digital mental health service</article-title>
          <source>Australas Psychiatry</source>
          <year>2019</year>
          <month>08</month>
          <volume>27</volume>
          <issue>4</issue>
          <fpage>352</fpage>
          <lpage>7</lpage>
          <pub-id pub-id-type="doi">10.1177/1039856218789784</pub-id>
          <pub-id pub-id-type="medline">30058351</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref62">
        <label>62</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>PM</given-names>
            </name>
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Terides</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Kayrouz</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Rapee</surname>
              <given-names>RM</given-names>
            </name>
          </person-group>
          <article-title>Improving adherence and clinical outcomes in self-guided internet treatment for anxiety and depression: a 12-month follow-up of a randomised controlled trial</article-title>
          <source>PLoS One</source>
          <year>2014</year>
          <volume>9</volume>
          <issue>2</issue>
          <fpage>e89591</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0089591"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0089591</pub-id>
          <pub-id pub-id-type="medline">24586897</pub-id>
          <pub-id pub-id-type="pii">PONE-D-13-29938</pub-id>
          <pub-id pub-id-type="pmcid">PMC3934918</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref63">
        <label>63</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Johnson</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Boyle</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Karin</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Kayrouz</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Treating anxiety and depression in young adults: a randomised controlled trial comparing clinician-guided versus self-guided Internet-delivered cognitive behavioural therapy</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2018</year>
          <month>07</month>
          <volume>52</volume>
          <issue>7</issue>
          <fpage>668</fpage>
          <lpage>79</lpage>
          <pub-id pub-id-type="doi">10.1177/0004867417738055</pub-id>
          <pub-id pub-id-type="medline">29064283</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref64">
        <label>64</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Gao</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Mihalopoulos</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>The cost-effectiveness of the online MindSpot clinic for the treatment of depression and anxiety in Australia</article-title>
          <source>J Ment Health Policy Econ</source>
          <year>2017</year>
          <month>12</month>
          <day>01</day>
          <volume>20</volume>
          <issue>4</issue>
          <fpage>155</fpage>
          <lpage>66</lpage>
          <pub-id pub-id-type="medline">29300702</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref65">
        <label>65</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kirkpatrick</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Manoukian</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>A feasibility open trial of internet-delivered cognitive-behavioural therapy (iCBT) among consumers of a non-governmental mental health organisation with anxiety</article-title>
          <source>PeerJ</source>
          <year>2013</year>
          <volume>1</volume>
          <fpage>e210</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.7717/peerj.210"/>
          </comment>
          <pub-id pub-id-type="doi">10.7717/peerj.210</pub-id>
          <pub-id pub-id-type="medline">24349897</pub-id>
          <pub-id pub-id-type="pii">210</pub-id>
          <pub-id pub-id-type="pmcid">PMC3845869</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref66">
        <label>66</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Terides</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Sheehan</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Kayrouz</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>PM</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Disorder-specific versus transdiagnostic and clinician-guided versus self-guided internet-delivered treatment for panic disorder and comorbid disorders: a randomized controlled trial</article-title>
          <source>J Anxiety Disord</source>
          <year>2016</year>
          <month>04</month>
          <volume>39</volume>
          <fpage>88</fpage>
          <lpage>102</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0887-6185(16)30034-2"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2016.03.005</pub-id>
          <pub-id pub-id-type="medline">27003376</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(16)30034-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref67">
        <label>67</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett-Levy</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Rapee</surname>
              <given-names>RM</given-names>
            </name>
            <name name-style="western">
              <surname>Shann</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Richards</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Ritterband</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Purtell</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Bezuidenhout</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Nielssen</surname>
              <given-names>OB</given-names>
            </name>
          </person-group>
          <article-title>MindSpot clinic: an accessible, efficient, and effective online treatment service for anxiety and depression</article-title>
          <source>Psychiatr Serv</source>
          <year>2015</year>
          <month>10</month>
          <volume>66</volume>
          <issue>10</issue>
          <fpage>1043</fpage>
          <lpage>50</lpage>
          <pub-id pub-id-type="doi">10.1176/appi.ps.201400477</pub-id>
          <pub-id pub-id-type="medline">26130001</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref68">
        <label>68</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Lorian</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Zou</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Spence</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>PM</given-names>
            </name>
            <name name-style="western">
              <surname>Rapee</surname>
              <given-names>RM</given-names>
            </name>
          </person-group>
          <article-title>Improving adherence and clinical outcomes in self-guided internet treatment for anxiety and depression: randomised controlled trial</article-title>
          <source>PLoS One</source>
          <year>2013</year>
          <volume>8</volume>
          <issue>7</issue>
          <fpage>e62873</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0062873"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0062873</pub-id>
          <pub-id pub-id-type="medline">23843932</pub-id>
          <pub-id pub-id-type="pii">PONE-D-12-28419</pub-id>
          <pub-id pub-id-type="pmcid">PMC3701078</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref69">
        <label>69</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Terides</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Sheehan</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Kayrouz</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>PM</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for Social Anxiety Disorder and comorbid disorders: a randomized controlled trial</article-title>
          <source>J Anxiety Disord</source>
          <year>2016</year>
          <month>08</month>
          <volume>42</volume>
          <fpage>30</fpage>
          <lpage>44</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0887-6185(16)30063-9"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2016.05.004</pub-id>
          <pub-id pub-id-type="medline">27261562</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(16)30063-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref70">
        <label>70</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Terides</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Karin</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Zou</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>BM</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>PM</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: a randomized controlled trial</article-title>
          <source>J Anxiety Disord</source>
          <year>2015</year>
          <month>12</month>
          <volume>36</volume>
          <fpage>63</fpage>
          <lpage>77</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0887-6185(15)30013-X"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2015.09.003</pub-id>
          <pub-id pub-id-type="medline">26460536</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(15)30013-X</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref71">
        <label>71</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Robinson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Spence</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Transdiagnostic internet treatment for anxiety disorders: a randomized controlled trial</article-title>
          <source>Behav Res Ther</source>
          <year>2010</year>
          <month>09</month>
          <volume>48</volume>
          <issue>9</issue>
          <fpage>890</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1016/j.brat.2010.05.014</pub-id>
          <pub-id pub-id-type="medline">20561606</pub-id>
          <pub-id pub-id-type="pii">S0005-7967(10)00110-5</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref72">
        <label>72</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Schwencke</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Craske</surname>
              <given-names>MG</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Transdiagnostic internet treatment for anxiety and depression: a randomised controlled trial</article-title>
          <source>Behav Res Ther</source>
          <year>2011</year>
          <month>08</month>
          <volume>49</volume>
          <issue>8</issue>
          <fpage>441</fpage>
          <lpage>52</lpage>
          <pub-id pub-id-type="doi">10.1016/j.brat.2011.03.007</pub-id>
          <pub-id pub-id-type="medline">21679925</pub-id>
          <pub-id pub-id-type="pii">S0005-7967(11)00079-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref73">
        <label>73</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Spence</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Comorbidity and internet-delivered transdiagnostic cognitive behavioural therapy for anxiety disorders</article-title>
          <source>Cogn Behav Ther</source>
          <year>2013</year>
          <volume>42</volume>
          <issue>3</issue>
          <fpage>180</fpage>
          <lpage>92</lpage>
          <pub-id pub-id-type="doi">10.1080/16506073.2012.753108</pub-id>
          <pub-id pub-id-type="medline">23458319</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref74">
        <label>74</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Spence</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
          </person-group>
          <article-title>A RCT of a transdiagnostic internet-delivered treatment for three anxiety disorders: examination of support roles and disorder-specific outcomes</article-title>
          <source>PLoS One</source>
          <year>2011</year>
          <volume>6</volume>
          <issue>11</issue>
          <fpage>e28079</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0028079"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0028079</pub-id>
          <pub-id pub-id-type="medline">22132216</pub-id>
          <pub-id pub-id-type="pii">PONE-D-11-04313</pub-id>
          <pub-id pub-id-type="pmcid">PMC3223218</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref75">
        <label>75</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Zou</surname>
              <given-names>JB</given-names>
            </name>
            <name name-style="western">
              <surname>Ali</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Lorian</surname>
              <given-names>CN</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Sheehan</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Clinical and cost-effectiveness of therapist-guided internet-delivered cognitive behavior therapy for older adults with symptoms of anxiety: a randomized controlled trial</article-title>
          <source>Behav Ther</source>
          <year>2015</year>
          <month>03</month>
          <volume>46</volume>
          <issue>2</issue>
          <fpage>206</fpage>
          <lpage>17</lpage>
          <pub-id pub-id-type="doi">10.1016/j.beth.2014.09.007</pub-id>
          <pub-id pub-id-type="medline">25645169</pub-id>
          <pub-id pub-id-type="pii">S0005-7894(14)00124-5</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref76">
        <label>76</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Ali</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Zou</surname>
              <given-names>JB</given-names>
            </name>
            <name name-style="western">
              <surname>Lorian</surname>
              <given-names>CN</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Terides</surname>
              <given-names>MD</given-names>
            </name>
            <name name-style="western">
              <surname>Kayrouz</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Klein</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
          </person-group>
          <article-title>Clinical and cost-effectiveness of therapist-guided internet-delivered cognitive behavior therapy for older adults with symptoms of depression: a randomized controlled trial</article-title>
          <source>Behav Ther</source>
          <year>2015</year>
          <month>03</month>
          <volume>46</volume>
          <issue>2</issue>
          <fpage>193</fpage>
          <lpage>205</lpage>
          <pub-id pub-id-type="doi">10.1016/j.beth.2014.09.008</pub-id>
          <pub-id pub-id-type="medline">25645168</pub-id>
          <pub-id pub-id-type="pii">S0005-7894(14)00125-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref77">
        <label>77</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zou</surname>
              <given-names>JB</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Lorian</surname>
              <given-names>CN</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Spence</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Knight</surname>
              <given-names>RG</given-names>
            </name>
            <name name-style="western">
              <surname>Anderson</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Sachdev</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Brief internet-delivered cognitive behavioral therapy for anxiety in older adults: a feasibility trial</article-title>
          <source>J Anxiety Disord</source>
          <year>2012</year>
          <month>08</month>
          <volume>26</volume>
          <issue>6</issue>
          <fpage>650</fpage>
          <lpage>5</lpage>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2012.04.002</pub-id>
          <pub-id pub-id-type="medline">22659078</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(12)00064-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref78">
        <label>78</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
            <name name-style="western">
              <surname>Nielssen</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Internet-delivered treatment for older adults with anxiety and depression: implementation of the Wellbeing Plus Course in routine clinical care and comparison with research trial outcomes</article-title>
          <source>BJPsych Open</source>
          <year>2016</year>
          <month>09</month>
          <volume>2</volume>
          <issue>5</issue>
          <fpage>307</fpage>
          <lpage>13</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.cambridge.org/core/product/identifier/S2056472400001769/type/journal_article"/>
          </comment>
          <pub-id pub-id-type="doi">10.1192/bjpo.bp.116.003400</pub-id>
          <pub-id pub-id-type="medline">27703794</pub-id>
          <pub-id pub-id-type="pii">S2056472400001769</pub-id>
          <pub-id pub-id-type="pmcid">PMC5022107</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref79">
        <label>79</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Fogliati</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>LG</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Wootton</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Nielssen</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
          </person-group>
          <article-title>Treating anxiety and depression in older adults: randomised controlled trial comparing guided v. self-guided internet-delivered cognitive-behavioural therapy</article-title>
          <source>BJPsych Open</source>
          <year>2016</year>
          <month>2</month>
          <day>1</day>
          <volume>2</volume>
          <issue>1</issue>
          <fpage>50</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.cambridge.org/core/product/identifier/S2056472400001150/type/journal_article"/>
          </comment>
          <pub-id pub-id-type="doi">10.1192/bjpo.bp.115.002139</pub-id>
          <pub-id pub-id-type="medline">27703754</pub-id>
          <pub-id pub-id-type="pii">S2056472400001150</pub-id>
          <pub-id pub-id-type="pmcid">PMC4995559</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref80">
        <label>80</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Read</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Sharpe</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Burton</surname>
              <given-names>AL</given-names>
            </name>
            <name name-style="western">
              <surname>Arean</surname>
              <given-names>PA</given-names>
            </name>
            <name name-style="western">
              <surname>Raue</surname>
              <given-names>PJ</given-names>
            </name>
            <name name-style="western">
              <surname>McDonald</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Gandy</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Dear</surname>
              <given-names>BF</given-names>
            </name>
          </person-group>
          <article-title>A randomized controlled trial of internet-delivered cognitive behaviour therapy to prevent the development of depressive disorders in older adults with multimorbidity</article-title>
          <source>J Affect Disord</source>
          <year>2020</year>
          <month>03</month>
          <day>01</day>
          <volume>264</volume>
          <fpage>464</fpage>
          <lpage>73</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2019.11.077</pub-id>
          <pub-id pub-id-type="medline">31767215</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(19)30828-6</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref81">
        <label>81</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Phillips</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Schneider</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Molosankwe</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Leese</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Foroushani</surname>
              <given-names>PS</given-names>
            </name>
            <name name-style="western">
              <surname>Grime</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>McCrone</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Morriss</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Thornicroft</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Randomized controlled trial of computerized cognitive behavioural therapy for depressive symptoms: effectiveness and costs of a workplace intervention</article-title>
          <source>Psychol Med</source>
          <year>2014</year>
          <month>03</month>
          <volume>44</volume>
          <issue>4</issue>
          <fpage>741</fpage>
          <lpage>52</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://journals.cambridge.org/abstract_S0033291713001323"/>
          </comment>
          <pub-id pub-id-type="doi">10.1017/S0033291713001323</pub-id>
          <pub-id pub-id-type="medline">23795621</pub-id>
          <pub-id pub-id-type="pii">S0033291713001323</pub-id>
          <pub-id pub-id-type="pmcid">PMC3898729</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref82">
        <label>82</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Korten</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Brittliffe</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Groves</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>A comparison of changes in anxiety and depression symptoms of spontaneous users and trial participants of a cognitive behavior therapy website</article-title>
          <source>J Med Internet Res</source>
          <year>2004</year>
          <month>12</month>
          <day>22</day>
          <volume>6</volume>
          <issue>4</issue>
          <fpage>e46</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2004/4/e46/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.6.4.e46</pub-id>
          <pub-id pub-id-type="medline">15631970</pub-id>
          <pub-id pub-id-type="pii">v6e46</pub-id>
          <pub-id pub-id-type="pmcid">PMC1550629</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref83">
        <label>83</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Comparative randomised trial of online cognitive-behavioural therapy and an information website for depression: 12-month outcomes</article-title>
          <source>Br J Psychiatry</source>
          <year>2008</year>
          <month>02</month>
          <volume>192</volume>
          <issue>2</issue>
          <fpage>130</fpage>
          <lpage>4</lpage>
          <pub-id pub-id-type="doi">10.1192/bjp.bp.106.032078</pub-id>
          <pub-id pub-id-type="medline">18245031</pub-id>
          <pub-id pub-id-type="pii">S0007125000233977</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref84">
        <label>84</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Korten</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Web-based cognitive behavior therapy: analysis of site usage and changes in depression and anxiety scores</article-title>
          <source>J Med Internet Res</source>
          <year>2002</year>
          <volume>4</volume>
          <issue>1</issue>
          <fpage>e3</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2002/1/e3/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.4.1.e3</pub-id>
          <pub-id pub-id-type="medline">11956035</pub-id>
          <pub-id pub-id-type="pii">&#60;ARTICLE_ID/&#62;</pub-id>
          <pub-id pub-id-type="pmcid">PMC1761927</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref85">
        <label>85</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Calear</surname>
              <given-names>AL</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>O'Kearney</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>The YouthMood Project: a cluster randomized controlled trial of an online cognitive behavioral program with adolescents</article-title>
          <source>J Consult Clin Psychol</source>
          <year>2009</year>
          <month>12</month>
          <volume>77</volume>
          <issue>6</issue>
          <fpage>1021</fpage>
          <lpage>32</lpage>
          <pub-id pub-id-type="doi">10.1037/a0017391</pub-id>
          <pub-id pub-id-type="medline">19968379</pub-id>
          <pub-id pub-id-type="pii">2009-22711-002</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref86">
        <label>86</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Brittliffe</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Online randomized controlled trial of brief and full cognitive behaviour therapy for depression</article-title>
          <source>Psychol Med</source>
          <year>2006</year>
          <month>12</month>
          <volume>36</volume>
          <issue>12</issue>
          <fpage>1737</fpage>
          <lpage>46</lpage>
          <pub-id pub-id-type="doi">10.1017/S0033291706008695</pub-id>
          <pub-id pub-id-type="medline">16938144</pub-id>
          <pub-id pub-id-type="pii">S0033291706008695</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref87">
        <label>87</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ellis</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Campbell</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Sethi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>O'Dea</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Comparative randomized trial of an online Cognitive-Behavioral Therapy program and an online support group for depression and anxiety</article-title>
          <source>J Cyber Ther Rehab</source>
          <year>2011</year>
          <volume>4</volume>
          <issue>4</issue>
          <fpage>461</fpage>
          <lpage>7</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.researchgate.net/publication/230814873_Comparative_randomized_trial_of_an_online_cognitive-behavioral_therapy_program_and_an_online_support_group_for_depression_and_anxiety"/>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref88">
        <label>88</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Farrer</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Internet-based CBT for depression with and without telephone tracking in a national helpline: randomised controlled trial</article-title>
          <source>PLoS One</source>
          <year>2011</year>
          <volume>6</volume>
          <issue>11</issue>
          <fpage>e28099</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0028099"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0028099</pub-id>
          <pub-id pub-id-type="medline">22140514</pub-id>
          <pub-id pub-id-type="pii">PONE-D-11-10667</pub-id>
          <pub-id pub-id-type="pmcid">PMC3227639</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref89">
        <label>89</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hickie</surname>
              <given-names>IB</given-names>
            </name>
            <name name-style="western">
              <surname>Davenport</surname>
              <given-names>TA</given-names>
            </name>
            <name name-style="western">
              <surname>Luscombe</surname>
              <given-names>GM</given-names>
            </name>
            <name name-style="western">
              <surname>Moore</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Practitioner-supported delivery of internet-based cognitive behaviour therapy: evaluation of the feasibility of conducting a cluster randomised trial</article-title>
          <source>Med J Aust</source>
          <year>2010</year>
          <month>06</month>
          <day>07</day>
          <volume>192</volume>
          <issue>S11</issue>
          <fpage>S31</fpage>
          <lpage>5</lpage>
          <pub-id pub-id-type="doi">10.5694/j.1326-5377.2010.tb03690.x</pub-id>
          <pub-id pub-id-type="medline">20528705</pub-id>
          <pub-id pub-id-type="pii">hic10838_fm</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref90">
        <label>90</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Sethi</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Campbell</surname>
              <given-names>AJ</given-names>
            </name>
            <name name-style="western">
              <surname>Ellis</surname>
              <given-names>LA</given-names>
            </name>
          </person-group>
          <article-title>The use of computerized self-help packages to treat adolescent depression and anxiety</article-title>
          <source>J Technol Human Serv</source>
          <year>2010</year>
          <month>08</month>
          <day>31</day>
          <volume>28</volume>
          <issue>3</issue>
          <fpage>144</fpage>
          <lpage>60</lpage>
          <pub-id pub-id-type="doi">10.1080/15228835.2010.508317</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref91">
        <label>91</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lintvedt</surname>
              <given-names>OK</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Sørensen</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Østvik</surname>
              <given-names>AR</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>CE</given-names>
            </name>
            <name name-style="western">
              <surname>Eisemann</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Waterloo</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Evaluating the effectiveness and efficacy of unguided internet-based self-help intervention for the prevention of depression: a randomized controlled trial</article-title>
          <source>Clin Psychol Psychother</source>
          <year>2013</year>
          <volume>20</volume>
          <issue>1</issue>
          <fpage>10</fpage>
          <lpage>27</lpage>
          <pub-id pub-id-type="doi">10.1002/cpp.770</pub-id>
          <pub-id pub-id-type="medline">21887811</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref92">
        <label>92</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Calear</surname>
              <given-names>AL</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Mackinnon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
          </person-group>
          <article-title>Adherence to the MoodGYM program: outcomes and predictors for an adolescent school-based population</article-title>
          <source>J Affect Disord</source>
          <year>2013</year>
          <month>05</month>
          <volume>147</volume>
          <issue>1-3</issue>
          <fpage>338</fpage>
          <lpage>44</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2012.11.036</pub-id>
          <pub-id pub-id-type="medline">23245469</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(12)00803-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref93">
        <label>93</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gilbody</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Littlewood</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Hewitt</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Brierley</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Tharmanathan</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Araya</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Barkham</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Bower</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Cooper</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Gask</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Kessler</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Lester</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Lovell</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Parry</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Richards</surname>
              <given-names>DA</given-names>
            </name>
            <name name-style="western">
              <surname>Andersen</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Brabyn</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Knowles</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Shepherd</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Tallon</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>White</surname>
              <given-names>D</given-names>
            </name>
            <collab>REEACT Team</collab>
          </person-group>
          <article-title>Computerised cognitive behaviour therapy (cCBT) as treatment for depression in primary care (REEACT trial): large scale pragmatic randomised controlled trial</article-title>
          <source>BMJ</source>
          <year>2015</year>
          <month>11</month>
          <day>11</day>
          <volume>351</volume>
          <fpage>h5627</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://www.bmj.com/lookup/pmidlookup?view=long&#38;pmid=26559241"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/bmj.h5627</pub-id>
          <pub-id pub-id-type="medline">26559241</pub-id>
          <pub-id pub-id-type="pmcid">PMC4641883</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref94">
        <label>94</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Høifødt</surname>
              <given-names>RS</given-names>
            </name>
            <name name-style="western">
              <surname>Lillevoll</surname>
              <given-names>KR</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Wilsgaard</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Eisemann</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Waterloo</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Kolstrup</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>The clinical effectiveness of web-based cognitive behavioral therapy with face-to-face therapist support for depressed primary care patients: randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2013</year>
          <month>08</month>
          <day>05</day>
          <volume>15</volume>
          <issue>8</issue>
          <fpage>e153</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2013/8/e153/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.2714</pub-id>
          <pub-id pub-id-type="medline">23916965</pub-id>
          <pub-id pub-id-type="pii">v15i8e153</pub-id>
          <pub-id pub-id-type="pmcid">PMC3742404</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref95">
        <label>95</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Powell</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hamborg</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Stallard</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Burls</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>McSorley</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Bennett</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness of a web-based cognitive-behavioral tool to improve mental well-being in the general population: randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2012</year>
          <month>12</month>
          <day>31</day>
          <volume>15</volume>
          <issue>1</issue>
          <fpage>e2</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2012/1/e2/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.2240</pub-id>
          <pub-id pub-id-type="medline">23302475</pub-id>
          <pub-id pub-id-type="pii">v15i1e2</pub-id>
          <pub-id pub-id-type="pmcid">PMC3636304</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref96">
        <label>96</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Sethi</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Treating youth depression and anxiety: a randomised controlled trial examining the efficacy of computerised versus face‐to‐face cognitive behaviour therapy</article-title>
          <source>Aust Psychol</source>
          <year>2020</year>
          <month>11</month>
          <day>12</day>
          <volume>48</volume>
          <issue>4</issue>
          <fpage>249</fpage>
          <lpage>57</lpage>
          <pub-id pub-id-type="doi">10.1111/ap.12006</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref97">
        <label>97</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Twomey</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>O'Reilly</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Byrne</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Bury</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>White</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Kissane</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>McMahon</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Clancy</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>A randomized controlled trial of the computerized CBT programme, MoodGYM, for public mental health service users waiting for interventions</article-title>
          <source>Br J Clin Psychol</source>
          <year>2014</year>
          <month>11</month>
          <volume>53</volume>
          <issue>4</issue>
          <fpage>433</fpage>
          <lpage>50</lpage>
          <pub-id pub-id-type="doi">10.1111/bjc.12055</pub-id>
          <pub-id pub-id-type="medline">24831119</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref98">
        <label>98</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Howell</surname>
              <given-names>AN</given-names>
            </name>
            <name name-style="western">
              <surname>Rheingold</surname>
              <given-names>AA</given-names>
            </name>
            <name name-style="western">
              <surname>Uhde</surname>
              <given-names>TW</given-names>
            </name>
            <name name-style="western">
              <surname>Guille</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Web-based CBT for the prevention of anxiety symptoms among medical and health science graduate students</article-title>
          <source>Cogn Behav Ther</source>
          <year>2019</year>
          <month>09</month>
          <volume>48</volume>
          <issue>5</issue>
          <fpage>385</fpage>
          <lpage>405</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/30526364"/>
          </comment>
          <pub-id pub-id-type="doi">10.1080/16506073.2018.1533575</pub-id>
          <pub-id pub-id-type="medline">30526364</pub-id>
          <pub-id pub-id-type="pmcid">PMC6559871</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref99">
        <label>99</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Löbner</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Pabst</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Stein</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Dorow</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Matschinger</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Luppa</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Maroß</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Kersting</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>König</surname>
              <given-names>H-H</given-names>
            </name>
            <name name-style="western">
              <surname>Riedel-Heller</surname>
              <given-names>SG</given-names>
            </name>
          </person-group>
          <article-title>Computerized cognitive behavior therapy for patients with mild to moderately severe depression in primary care: a pragmatic cluster randomized controlled trial (@ktiv)</article-title>
          <source>J Affect Disord</source>
          <year>2018</year>
          <month>10</month>
          <day>01</day>
          <volume>238</volume>
          <fpage>317</fpage>
          <lpage>26</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2018.06.008</pub-id>
          <pub-id pub-id-type="medline">29902736</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(18)30515-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref100">
        <label>100</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>O'Kearney</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Gibson</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>KM</given-names>
            </name>
          </person-group>
          <article-title>Effects of a cognitive-behavioural internet program on depression, vulnerability to depression and stigma in adolescent males: a school-based controlled trial</article-title>
          <source>Cogn Behav Ther</source>
          <year>2006</year>
          <volume>35</volume>
          <issue>1</issue>
          <fpage>43</fpage>
          <lpage>54</lpage>
          <pub-id pub-id-type="doi">10.1080/16506070500303456</pub-id>
          <pub-id pub-id-type="medline">16500776</pub-id>
          <pub-id pub-id-type="pii">J4367U7813T585J0</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref101">
        <label>101</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>O'Kearney</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Kang</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>A controlled trial of a school-based internet program for reducing depressive symptoms in adolescent girls</article-title>
          <source>Depress Anxiety</source>
          <year>2009</year>
          <volume>26</volume>
          <issue>1</issue>
          <fpage>65</fpage>
          <lpage>72</lpage>
          <pub-id pub-id-type="doi">10.1002/da.20507</pub-id>
          <pub-id pub-id-type="medline">18828141</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref102">
        <label>102</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Groves</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Korten</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Free range users and one hit wonders: community users of an internet-based cognitive behaviour therapy program</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2006</year>
          <month>01</month>
          <volume>40</volume>
          <issue>1</issue>
          <fpage>59</fpage>
          <lpage>62</lpage>
          <pub-id pub-id-type="doi">10.1080/j.1440-1614.2006.01743.x</pub-id>
          <pub-id pub-id-type="medline">16403040</pub-id>
          <pub-id pub-id-type="pii">ANP1743</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref103">
        <label>103</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Danaher</surname>
              <given-names>BG</given-names>
            </name>
            <name name-style="western">
              <surname>Milgrom</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Seeley</surname>
              <given-names>JR</given-names>
            </name>
            <name name-style="western">
              <surname>Stuart</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Schembri</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Tyler</surname>
              <given-names>MS</given-names>
            </name>
            <name name-style="western">
              <surname>Ericksen</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Lester</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Gemmill</surname>
              <given-names>AW</given-names>
            </name>
            <name name-style="western">
              <surname>Lewinsohn</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Web-based intervention for postpartum depression: formative research and design of the MomMoodBooster program</article-title>
          <source>JMIR Res Protoc</source>
          <year>2012</year>
          <month>11</month>
          <day>22</day>
          <volume>1</volume>
          <issue>2</issue>
          <fpage>e18</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.researchprotocols.org/2012/2/e18/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/resprot.2329</pub-id>
          <pub-id pub-id-type="medline">23612274</pub-id>
          <pub-id pub-id-type="pii">v1i2e18</pub-id>
          <pub-id pub-id-type="pmcid">PMC3626158</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref104">
        <label>104</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Danaher</surname>
              <given-names>BG</given-names>
            </name>
            <name name-style="western">
              <surname>Milgrom</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Seeley</surname>
              <given-names>JR</given-names>
            </name>
            <name name-style="western">
              <surname>Stuart</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Schembri</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Tyler</surname>
              <given-names>MS</given-names>
            </name>
            <name name-style="western">
              <surname>Ericksen</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Lester</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Gemmill</surname>
              <given-names>AW</given-names>
            </name>
            <name name-style="western">
              <surname>Kosty</surname>
              <given-names>DB</given-names>
            </name>
            <name name-style="western">
              <surname>Lewinsohn</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>MomMoodBooster web-based intervention for postpartum depression: feasibility trial results</article-title>
          <source>J Med Internet Res</source>
          <year>2013</year>
          <month>11</month>
          <day>04</day>
          <volume>15</volume>
          <issue>11</issue>
          <fpage>e242</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2013/11/e242/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.2876</pub-id>
          <pub-id pub-id-type="medline">24191345</pub-id>
          <pub-id pub-id-type="pii">v15i11e242</pub-id>
          <pub-id pub-id-type="pmcid">PMC3841354</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref105">
        <label>105</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Milgrom</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Danaher</surname>
              <given-names>BG</given-names>
            </name>
            <name name-style="western">
              <surname>Gemmill</surname>
              <given-names>AW</given-names>
            </name>
            <name name-style="western">
              <surname>Holt</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Holt</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Seeley</surname>
              <given-names>JR</given-names>
            </name>
            <name name-style="western">
              <surname>Tyler</surname>
              <given-names>MS</given-names>
            </name>
            <name name-style="western">
              <surname>Ross</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ericksen</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Internet cognitive behavioral therapy for women with postnatal depression: a randomized controlled trial of MumMoodBooster</article-title>
          <source>J Med Internet Res</source>
          <year>2016</year>
          <month>03</month>
          <day>07</day>
          <volume>18</volume>
          <issue>3</issue>
          <fpage>e54</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2016/3/e54/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.4993</pub-id>
          <pub-id pub-id-type="medline">26952645</pub-id>
          <pub-id pub-id-type="pii">v18i3e54</pub-id>
          <pub-id pub-id-type="pmcid">PMC4802107</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref106">
        <label>106</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Clarke</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Proudfoot</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ma</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Mobile phone and web-based cognitive behavior therapy for depressive symptoms and mental health comorbidities in people living with diabetes: results of a feasibility study</article-title>
          <source>JMIR Ment Health</source>
          <year>2016</year>
          <month>05</month>
          <day>31</day>
          <volume>3</volume>
          <issue>2</issue>
          <fpage>e23</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2016/2/e23/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/mental.5131</pub-id>
          <pub-id pub-id-type="medline">27245948</pub-id>
          <pub-id pub-id-type="pii">v3i2e23</pub-id>
          <pub-id pub-id-type="pmcid">PMC4908303</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref107">
        <label>107</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Harrison</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Proudfoot</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Wee</surname>
              <given-names>PP</given-names>
            </name>
            <name name-style="western">
              <surname>Parker</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Pavlovic</surname>
              <given-names>DH</given-names>
            </name>
            <name name-style="western">
              <surname>Manicavasagar</surname>
              <given-names>V</given-names>
            </name>
          </person-group>
          <article-title>Mobile mental health: review of the emerging field and proof of concept study</article-title>
          <source>J Ment Health</source>
          <year>2011</year>
          <month>12</month>
          <volume>20</volume>
          <issue>6</issue>
          <fpage>509</fpage>
          <lpage>24</lpage>
          <pub-id pub-id-type="doi">10.3109/09638237.2011.608746</pub-id>
          <pub-id pub-id-type="medline">21988230</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref108">
        <label>108</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Proudfoot</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Clarke</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Birch</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Whitton</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Parker</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Manicavasagar</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Harrison</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Hadzi-Pavlovic</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Impact of a mobile phone and web program on symptom and functional outcomes for people with mild-to-moderate depression, anxiety and stress: a randomised controlled trial</article-title>
          <source>BMC Psychiatry</source>
          <year>2013</year>
          <month>11</month>
          <day>18</day>
          <volume>13</volume>
          <fpage>312</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcpsychiatry.biomedcentral.com/articles/10.1186/1471-244X-13-312"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1471-244X-13-312</pub-id>
          <pub-id pub-id-type="medline">24237617</pub-id>
          <pub-id pub-id-type="pii">1471-244X-13-312</pub-id>
          <pub-id pub-id-type="pmcid">PMC4225666</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref109">
        <label>109</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Clarke</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Proudfoot</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Birch</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Whitton</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Parker</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Manicavasagar</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Harrison</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Hadzi-Pavlovic</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Effects of mental health self-efficacy on outcomes of a mobile phone and web intervention for mild-to-moderate depression, anxiety and stress: secondary analysis of a randomised controlled trial</article-title>
          <source>BMC Psychiatry</source>
          <year>2014</year>
          <month>09</month>
          <day>26</day>
          <volume>14</volume>
          <fpage>272</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-014-0272-1"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s12888-014-0272-1</pub-id>
          <pub-id pub-id-type="medline">25252853</pub-id>
          <pub-id pub-id-type="pii">s12888-014-0272-1</pub-id>
          <pub-id pub-id-type="pmcid">PMC4189737</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref110">
        <label>110</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Baldwin</surname>
              <given-names>PA</given-names>
            </name>
            <name name-style="western">
              <surname>Sanatkar</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Clarke</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Fletcher</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Gunn</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Wilhelm</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Campbell</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Zwar</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Harris</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Lapsley</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Hadzi-Pavlovic</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Proudfoot</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>A web-based mental health intervention to improve social and occupational functioning in adults with type 2 diabetes (the springboard trial): 12-month outcomes of a randomized controlled trial</article-title>
          <source>J Med Internet Res</source>
          <year>2020</year>
          <month>12</month>
          <day>01</day>
          <volume>22</volume>
          <issue>12</issue>
          <fpage>e16729</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2020/12/e16729/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/16729</pub-id>
          <pub-id pub-id-type="medline">33258790</pub-id>
          <pub-id pub-id-type="pii">v22i12e16729</pub-id>
          <pub-id pub-id-type="pmcid">PMC7738252</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref111">
        <label>111</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Mewton</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Transdiagnostic versus disorder-specific internet-delivered cognitive behaviour therapy for anxiety and depression in primary care</article-title>
          <source>J Anxiety Disord</source>
          <year>2017</year>
          <month>03</month>
          <volume>46</volume>
          <fpage>25</fpage>
          <lpage>34</lpage>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2016.06.002</pub-id>
          <pub-id pub-id-type="medline">27396841</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(16)30082-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref112">
        <label>112</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Sunderland</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Wong</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Hilvert-Bruce</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Investigating trajectories of change in psychological distress amongst patients with depression and generalised anxiety disorder treated with internet cognitive behavioural therapy</article-title>
          <source>Behav Res Ther</source>
          <year>2012</year>
          <month>06</month>
          <volume>50</volume>
          <issue>6</issue>
          <fpage>374</fpage>
          <lpage>80</lpage>
          <pub-id pub-id-type="doi">10.1016/j.brat.2012.03.005</pub-id>
          <pub-id pub-id-type="medline">22498311</pub-id>
          <pub-id pub-id-type="pii">S0005-7967(12)00055-1</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref113">
        <label>113</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Perini</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The Climate Sadness program: an open trial of internet-based treatment for depression</article-title>
          <source>E J Applied Psychol</source>
          <year>2008</year>
          <month>12</month>
          <day>23</day>
          <volume>4</volume>
          <issue>2</issue>
          <fpage>18</fpage>
          <lpage>24</lpage>
          <pub-id pub-id-type="doi">10.7790/ejap.v4i2.135</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref114">
        <label>114</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>AD</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of internet cognitive behavioural therapy (iCBT) for depression in primary care: a quality assurance study</article-title>
          <source>PLoS One</source>
          <year>2013</year>
          <volume>8</volume>
          <issue>2</issue>
          <fpage>e57447</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0057447"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0057447</pub-id>
          <pub-id pub-id-type="medline">23451231</pub-id>
          <pub-id pub-id-type="pii">PONE-D-12-30131</pub-id>
          <pub-id pub-id-type="pmcid">PMC3579844</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref115">
        <label>115</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Watts</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Mewton</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>A clinical audit of changes in suicide ideas with internet treatment for depression</article-title>
          <source>BMJ Open</source>
          <year>2012</year>
          <volume>2</volume>
          <issue>5</issue>
          <fpage>e001558</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmjopen.bmj.com/lookup/pmidlookup?view=long&#38;pmid=22983787"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/bmjopen-2012-001558</pub-id>
          <pub-id pub-id-type="medline">22983787</pub-id>
          <pub-id pub-id-type="pii">bmjopen-2012-001558</pub-id>
          <pub-id pub-id-type="pmcid">PMC3467611</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref116">
        <label>116</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mewton</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Cognitive behaviour therapy via the internet for depression: a useful strategy to reduce suicidal ideation</article-title>
          <source>J Affect Disord</source>
          <year>2015</year>
          <month>01</month>
          <day>01</day>
          <volume>170</volume>
          <fpage>78</fpage>
          <lpage>84</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2014.08.038</pub-id>
          <pub-id pub-id-type="medline">25233243</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(14)00527-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref117">
        <label>117</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hobbs</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Joubert</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Treating late-life depression: comparing the effects of internet-delivered cognitive behavior therapy across the adult lifespan</article-title>
          <source>J Affect Disord</source>
          <year>2018</year>
          <month>01</month>
          <day>15</day>
          <volume>226</volume>
          <fpage>58</fpage>
          <lpage>65</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2017.09.026</pub-id>
          <pub-id pub-id-type="medline">28963865</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(17)31568-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref118">
        <label>118</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Perini</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Clinician-assisted internet-based treatment is effective for depression: randomized controlled trial</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2009</year>
          <month>06</month>
          <volume>43</volume>
          <issue>6</issue>
          <fpage>571</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1080/00048670902873722</pub-id>
          <pub-id pub-id-type="medline">19440890</pub-id>
          <pub-id pub-id-type="pii">911151658</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref119">
        <label>119</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Davies</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>McIntyre</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Robinson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Solley</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Internet treatment for depression: a randomized controlled trial comparing clinician vs. technician assistance</article-title>
          <source>PLoS One</source>
          <year>2010</year>
          <month>06</month>
          <day>08</day>
          <volume>5</volume>
          <issue>6</issue>
          <fpage>e10939</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0010939"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0010939</pub-id>
          <pub-id pub-id-type="medline">20544030</pub-id>
          <pub-id pub-id-type="pmcid">PMC2882336</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref120">
        <label>120</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rosso</surname>
              <given-names>IM</given-names>
            </name>
            <name name-style="western">
              <surname>Killgore</surname>
              <given-names>WD</given-names>
            </name>
            <name name-style="western">
              <surname>Olson</surname>
              <given-names>EA</given-names>
            </name>
            <name name-style="western">
              <surname>Webb</surname>
              <given-names>CA</given-names>
            </name>
            <name name-style="western">
              <surname>Fukunaga</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Auerbach</surname>
              <given-names>RP</given-names>
            </name>
            <name name-style="western">
              <surname>Gogel</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Buchholz</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>Rauch</surname>
              <given-names>SL</given-names>
            </name>
          </person-group>
          <article-title>Internet-based cognitive behavior therapy for major depressive disorder: a randomized controlled trial</article-title>
          <source>Depress Anxiety</source>
          <year>2017</year>
          <month>03</month>
          <volume>34</volume>
          <issue>3</issue>
          <fpage>236</fpage>
          <lpage>45</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/28009467"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/da.22590</pub-id>
          <pub-id pub-id-type="medline">28009467</pub-id>
          <pub-id pub-id-type="pmcid">PMC5540163</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref121">
        <label>121</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Burston</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Murphy</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Michael</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Mackenzie</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Kiln</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Loughnan</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>O'Moore</surname>
              <given-names>KA</given-names>
            </name>
            <name name-style="western">
              <surname>Allard</surname>
              <given-names>BJ</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>AD</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Help from home for depression: a randomised controlled trial comparing internet-delivered cognitive behaviour therapy with bibliotherapy for depression</article-title>
          <source>Internet Interv</source>
          <year>2017</year>
          <month>09</month>
          <volume>9</volume>
          <fpage>25</fpage>
          <lpage>37</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(17)30022-2"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2017.05.001</pub-id>
          <pub-id pub-id-type="medline">30135834</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(17)30022-2</pub-id>
          <pub-id pub-id-type="pmcid">PMC6096313</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref122">
        <label>122</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Watts</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Mackenzie</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Thomas</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Griskaitis</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Mewton</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>CBT for depression: a pilot RCT comparing mobile phone vs. computer</article-title>
          <source>BMC Psychiatry</source>
          <year>2013</year>
          <month>02</month>
          <day>07</day>
          <volume>13</volume>
          <fpage>49</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmcpsychiatry.biomedcentral.com/articles/10.1186/1471-244X-13-49"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1471-244X-13-49</pub-id>
          <pub-id pub-id-type="medline">23391304</pub-id>
          <pub-id pub-id-type="pii">1471-244X-13-49</pub-id>
          <pub-id pub-id-type="pmcid">PMC3571935</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref123">
        <label>123</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>O'moore</surname>
              <given-names>KA</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Hunter</surname>
              <given-names>DJ</given-names>
            </name>
            <name name-style="western">
              <surname>Bennell</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>AD</given-names>
            </name>
          </person-group>
          <article-title>Internet cognitive-behavioral therapy for depression in older adults with knee osteoarthritis: a randomized controlled trial</article-title>
          <source>Arthritis Care Res (Hoboken)</source>
          <year>2018</year>
          <month>01</month>
          <volume>70</volume>
          <issue>1</issue>
          <fpage>61</fpage>
          <lpage>70</lpage>
          <pub-id pub-id-type="doi">10.1002/acr.23257</pub-id>
          <pub-id pub-id-type="medline">28426917</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref124">
        <label>124</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Fletcher</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Chondros</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Densley</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Murray</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Dowrick</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Coe</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hegarty</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Davidson</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Wachtler</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Mihalopoulos</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Lee</surname>
              <given-names>YY</given-names>
            </name>
            <name name-style="western">
              <surname>Chatterton</surname>
              <given-names>ML</given-names>
            </name>
            <name name-style="western">
              <surname>Palmer</surname>
              <given-names>VJ</given-names>
            </name>
            <name name-style="western">
              <surname>Gunn</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Matching depression management to severity prognosis in primary care: results of the Target-D randomised controlled trial</article-title>
          <source>Br J Gen Pract</source>
          <year>2021</year>
          <volume>71</volume>
          <issue>703</issue>
          <fpage>85</fpage>
          <lpage>94</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/33431380"/>
          </comment>
          <pub-id pub-id-type="doi">10.3399/BJGP.2020.0783</pub-id>
          <pub-id pub-id-type="medline">33431380</pub-id>
          <pub-id pub-id-type="pmcid">PMC7846356</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref125">
        <label>125</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hilvert-Bruce</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>Rossouw</surname>
              <given-names>PJ</given-names>
            </name>
            <name name-style="western">
              <surname>Wong</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Sunderland</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Adherence as a determinant of effectiveness of internet cognitive behavioural therapy for anxiety and depressive disorders</article-title>
          <source>Behav Res Ther</source>
          <year>2012</year>
          <month>08</month>
          <volume>50</volume>
          <issue>7-8</issue>
          <fpage>463</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1016/j.brat.2012.04.001</pub-id>
          <pub-id pub-id-type="medline">22659155</pub-id>
          <pub-id pub-id-type="pii">S0005-7967(12)00070-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref126">
        <label>126</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Mason</surname>
              <given-names>EC</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Uppal</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Pilot trial of a therapist-supported internet-delivered cognitive behavioural therapy program for health anxiety</article-title>
          <source>Internet Interv</source>
          <year>2016</year>
          <month>11</month>
          <volume>6</volume>
          <fpage>71</fpage>
          <lpage>9</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(16)30037-9"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2016.09.007</pub-id>
          <pub-id pub-id-type="medline">30135816</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(16)30037-9</pub-id>
          <pub-id pub-id-type="pmcid">PMC6096191</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref127">
        <label>127</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Haskelberg</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Hobbs</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Mason</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of internet-delivered cognitive behavioural therapy for health anxiety in routine care</article-title>
          <source>J Affect Disord</source>
          <year>2020</year>
          <month>03</month>
          <day>01</day>
          <volume>264</volume>
          <fpage>535</fpage>
          <lpage>42</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2019.11.087</pub-id>
          <pub-id pub-id-type="medline">31780130</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(19)31648-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref128">
        <label>128</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Uppal</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Mason</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Internet-based cognitive behavioral therapy versus psychoeducation control for illness anxiety disorder and somatic symptom disorder: a randomized controlled trial</article-title>
          <source>J Consult Clin Psychol</source>
          <year>2018</year>
          <month>01</month>
          <volume>86</volume>
          <issue>1</issue>
          <fpage>89</fpage>
          <lpage>98</lpage>
          <pub-id pub-id-type="doi">10.1037/ccp0000248</pub-id>
          <pub-id pub-id-type="medline">29172593</pub-id>
          <pub-id pub-id-type="pii">2017-52451-001</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref129">
        <label>129</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kladnitski</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Allen</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>Online mindfulness-enhanced cognitive behavioural therapy for anxiety and depression: outcomes of a pilot trial</article-title>
          <source>Internet Interv</source>
          <year>2018</year>
          <month>09</month>
          <volume>13</volume>
          <fpage>41</fpage>
          <lpage>50</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(18)30007-1"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2018.06.003</pub-id>
          <pub-id pub-id-type="medline">30206518</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(18)30007-1</pub-id>
          <pub-id pub-id-type="pmcid">PMC6112099</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref130">
        <label>130</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kladnitski</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Uppal</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>James</surname>
              <given-names>MA</given-names>
            </name>
            <name name-style="western">
              <surname>Allen</surname>
              <given-names>AR</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>Transdiagnostic internet-delivered CBT and mindfulness-based treatment for depression and anxiety: a randomised controlled trial</article-title>
          <source>Internet Interv</source>
          <year>2020</year>
          <month>04</month>
          <volume>20</volume>
          <fpage>100310</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(19)30128-9"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2020.100310</pub-id>
          <pub-id pub-id-type="medline">32140427</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(19)30128-9</pub-id>
          <pub-id pub-id-type="pmcid">PMC7044661</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref131">
        <label>131</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Mewton</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>AD</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness of transdiagnostic internet cognitive behavioural treatment for mixed anxiety and depression in primary care</article-title>
          <source>J Affect Disord</source>
          <year>2014</year>
          <month>08</month>
          <volume>165</volume>
          <fpage>45</fpage>
          <lpage>52</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2014.04.037</pub-id>
          <pub-id pub-id-type="medline">24882176</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(14)00231-6</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref132">
        <label>132</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Morgan</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Mason</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Hobbs</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>McAloon</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of unguided internet cognitive behavioural therapy for mixed anxiety and depression</article-title>
          <source>Internet Interv</source>
          <year>2017</year>
          <month>12</month>
          <volume>10</volume>
          <fpage>47</fpage>
          <lpage>53</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(17)30012-X"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2017.10.003</pub-id>
          <pub-id pub-id-type="medline">30135752</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(17)30012-X</pub-id>
          <pub-id pub-id-type="pmcid">PMC6084910</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref133">
        <label>133</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Hobbs</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>AD</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Reducing behavioral avoidance with internet-delivered cognitive behavior therapy for generalized anxiety disorder</article-title>
          <source>Internet Interv</source>
          <year>2019</year>
          <month>03</month>
          <volume>15</volume>
          <fpage>105</fpage>
          <lpage>9</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(17)30054-4"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2017.11.004</pub-id>
          <pub-id pub-id-type="medline">30792961</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(17)30054-4</pub-id>
          <pub-id pub-id-type="pmcid">PMC6371407</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref134">
        <label>134</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Mackenzie</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>AD</given-names>
            </name>
            <name name-style="western">
              <surname>McIntyre</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Watts</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Wong</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Internet cognitive behavioural therapy for mixed anxiety and depression: a randomized controlled trial and evidence of effectiveness in primary care</article-title>
          <source>Psychol Med</source>
          <year>2013</year>
          <month>12</month>
          <volume>43</volume>
          <issue>12</issue>
          <fpage>2635</fpage>
          <lpage>48</lpage>
          <pub-id pub-id-type="doi">10.1017/S0033291713000111</pub-id>
          <pub-id pub-id-type="medline">23419552</pub-id>
          <pub-id pub-id-type="pii">S0033291713000111</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref135">
        <label>135</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Loughnan</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>Sie</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hobbs</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Joubert</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Haskelberg</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Kladnitski</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Holt</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Milgrom</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Austin</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>A randomized controlled trial of 'MUMentum Pregnancy': internet-delivered cognitive behavioral therapy program for antenatal anxiety and depression</article-title>
          <source>J Affect Disord</source>
          <year>2019</year>
          <month>01</month>
          <day>15</day>
          <volume>243</volume>
          <fpage>381</fpage>
          <lpage>90</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jad.2018.09.057</pub-id>
          <pub-id pub-id-type="medline">30266030</pub-id>
          <pub-id pub-id-type="pii">S0165-0327(18)31106-6</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref136">
        <label>136</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Loughnan</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>Butler</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Sie</surname>
              <given-names>AA</given-names>
            </name>
            <name name-style="western">
              <surname>Grierson</surname>
              <given-names>AB</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>AZ</given-names>
            </name>
            <name name-style="western">
              <surname>Hobbs</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Joubert</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Haskelberg</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Holt</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Gemmill</surname>
              <given-names>AW</given-names>
            </name>
            <name name-style="western">
              <surname>Milgrom</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Austin</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
          </person-group>
          <article-title>A randomised controlled trial of 'MUMentum postnatal': internet-delivered cognitive behavioural therapy for anxiety and depression in postpartum women</article-title>
          <source>Behav Res Ther</source>
          <year>2019</year>
          <month>05</month>
          <volume>116</volume>
          <fpage>94</fpage>
          <lpage>103</lpage>
          <pub-id pub-id-type="doi">10.1016/j.brat.2019.03.001</pub-id>
          <pub-id pub-id-type="medline">30877878</pub-id>
          <pub-id pub-id-type="pii">S0005-7967(19)30042-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref137">
        <label>137</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wims</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The Climate Panic program: an open trial of internet-based treatment for panic disorder</article-title>
          <source>E J Applied Psychol</source>
          <year>2008</year>
          <month>12</month>
          <day>23</day>
          <volume>4</volume>
          <issue>2</issue>
          <pub-id pub-id-type="doi">10.7790/ejap.v4i2.134</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref138">
        <label>138</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bell</surname>
              <given-names>CJ</given-names>
            </name>
            <name name-style="western">
              <surname>Colhoun</surname>
              <given-names>HC</given-names>
            </name>
            <name name-style="western">
              <surname>Carter</surname>
              <given-names>FA</given-names>
            </name>
            <name name-style="western">
              <surname>Frampton</surname>
              <given-names>CM</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness of computerised cognitive behaviour therapy for anxiety disorders in secondary care</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2012</year>
          <month>07</month>
          <volume>46</volume>
          <issue>7</issue>
          <fpage>630</fpage>
          <lpage>40</lpage>
          <pub-id pub-id-type="doi">10.1177/0004867412437345</pub-id>
          <pub-id pub-id-type="medline">22327097</pub-id>
          <pub-id pub-id-type="pii">0004867412437345</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref139">
        <label>139</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wims</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>I</given-names>
            </name>
          </person-group>
          <article-title>Clinician-assisted Internet-based treatment is effective for panic: a randomized controlled trial</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2010</year>
          <month>07</month>
          <volume>44</volume>
          <issue>7</issue>
          <fpage>599</fpage>
          <lpage>607</lpage>
          <pub-id pub-id-type="doi">10.3109/00048671003614171</pub-id>
          <pub-id pub-id-type="medline">20560847</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref140">
        <label>140</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Allen</surname>
              <given-names>AR</given-names>
            </name>
            <name name-style="western">
              <surname>Newby</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Mackenzie</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Boulton</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Loughnan</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Internet cognitive-behavioural treatment for panic disorder: randomised controlled trial and evidence of effectiveness in primary care</article-title>
          <source>BJPsych Open</source>
          <year>2016</year>
          <month>03</month>
          <volume>2</volume>
          <issue>2</issue>
          <fpage>154</fpage>
          <lpage>62</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.cambridge.org/core/product/identifier/S2056472400001290/type/journal_article"/>
          </comment>
          <pub-id pub-id-type="doi">10.1192/bjpo.bp.115.001826</pub-id>
          <pub-id pub-id-type="medline">27703768</pub-id>
          <pub-id pub-id-type="pii">S2056472400001290</pub-id>
          <pub-id pub-id-type="pmcid">PMC4998930</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref141">
        <label>141</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Aydos</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Shyness 5: the clinical effectiveness of Internet-based clinician-assisted treatment of social phobia</article-title>
          <source>Australas Psychiatry</source>
          <year>2009</year>
          <month>12</month>
          <volume>17</volume>
          <issue>6</issue>
          <fpage>488</fpage>
          <lpage>92</lpage>
          <pub-id pub-id-type="doi">10.1080/10398560903284943</pub-id>
          <pub-id pub-id-type="medline">20001373</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref142">
        <label>142</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Schwencke</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Drobny</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Einstein</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Shyness 1: distance treatment of social phobia over the internet</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2008</year>
          <month>07</month>
          <volume>42</volume>
          <issue>7</issue>
          <fpage>585</fpage>
          <lpage>94</lpage>
          <pub-id pub-id-type="doi">10.1080/00048670802119762</pub-id>
          <pub-id pub-id-type="medline">18612862</pub-id>
          <pub-id pub-id-type="pii">794820327</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref143">
        <label>143</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Schwencke</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Shyness 2: treating social phobia online: replication and extension</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2008</year>
          <month>07</month>
          <volume>42</volume>
          <issue>7</issue>
          <fpage>595</fpage>
          <lpage>605</lpage>
          <pub-id pub-id-type="doi">10.1080/00048670802119820</pub-id>
          <pub-id pub-id-type="medline">18612863</pub-id>
          <pub-id pub-id-type="pii">794820392</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref144">
        <label>144</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Schwencke</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Shyness 3: randomized controlled trial of guided versus unguided internet-based CBT for social phobia</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2008</year>
          <month>12</month>
          <volume>42</volume>
          <issue>12</issue>
          <fpage>1030</fpage>
          <lpage>40</lpage>
          <pub-id pub-id-type="doi">10.1080/00048670802512107</pub-id>
          <pub-id pub-id-type="medline">19016091</pub-id>
          <pub-id pub-id-type="pii">905606265</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref145">
        <label>145</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Davies</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Effectiveness randomized controlled trial of face to face versus internet cognitive behaviour therapy for social phobia</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2011</year>
          <month>04</month>
          <volume>45</volume>
          <issue>4</issue>
          <fpage>337</fpage>
          <lpage>40</lpage>
          <pub-id pub-id-type="doi">10.3109/00048674.2010.538840</pub-id>
          <pub-id pub-id-type="medline">21323490</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref146">
        <label>146</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Gibson</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>McEvoy</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Internet treatment for social phobia reduces comorbidity</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2009</year>
          <month>08</month>
          <volume>43</volume>
          <issue>8</issue>
          <fpage>754</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1080/00048670903001992</pub-id>
          <pub-id pub-id-type="medline">19629797</pub-id>
          <pub-id pub-id-type="pii">913239731</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref147">
        <label>147</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mewton</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Wong</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>The effectiveness of internet cognitive behavioural therapy for generalized anxiety disorder in clinical practice</article-title>
          <source>Depress Anxiety</source>
          <year>2012</year>
          <month>10</month>
          <volume>29</volume>
          <issue>10</issue>
          <fpage>843</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1002/da.21995</pub-id>
          <pub-id pub-id-type="medline">22949296</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref148">
        <label>148</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hobbs</surname>
              <given-names>MJ</given-names>
            </name>
            <name name-style="western">
              <surname>Mahoney</surname>
              <given-names>AE</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Integrating iCBT for generalized anxiety disorder into routine clinical care: treatment effects across the adult lifespan</article-title>
          <source>J Anxiety Disord</source>
          <year>2017</year>
          <month>10</month>
          <volume>51</volume>
          <fpage>47</fpage>
          <lpage>54</lpage>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2017.09.003</pub-id>
          <pub-id pub-id-type="medline">28926805</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(17)30232-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref149">
        <label>149</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Robinson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>McIntyre</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Schwencke</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Solley</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Internet treatment for generalized anxiety disorder: a randomized controlled trial comparing clinician vs. technician assistance</article-title>
          <source>PLoS One</source>
          <year>2010</year>
          <month>06</month>
          <day>03</day>
          <volume>5</volume>
          <issue>6</issue>
          <fpage>e10942</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0010942"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0010942</pub-id>
          <pub-id pub-id-type="medline">20532167</pub-id>
          <pub-id pub-id-type="pmcid">PMC2880592</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref150">
        <label>150</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Andrews</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Robinson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Schwencke</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Johnston</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Solley</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Choi</surname>
              <given-names>I</given-names>
            </name>
          </person-group>
          <article-title>Clinician-assisted internet-based treatment is effective for generalized anxiety disorder: randomized controlled trial</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2009</year>
          <month>01</month>
          <day>01</day>
          <volume>43</volume>
          <issue>10</issue>
          <fpage>905</fpage>
          <lpage>12</lpage>
          <pub-id pub-id-type="doi">10.1080/00048670903179269</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref151">
        <label>151</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lorian</surname>
              <given-names>CN</given-names>
            </name>
            <name name-style="western">
              <surname>Titov</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Grisham</surname>
              <given-names>JR</given-names>
            </name>
          </person-group>
          <article-title>Changes in risk-taking over the course of an internet-delivered cognitive behavioral therapy treatment for generalized anxiety disorder</article-title>
          <source>J Anxiety Disord</source>
          <year>2012</year>
          <month>01</month>
          <volume>26</volume>
          <issue>1</issue>
          <fpage>140</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1016/j.janxdis.2011.10.003</pub-id>
          <pub-id pub-id-type="medline">22079215</pub-id>
          <pub-id pub-id-type="pii">S0887-6185(11)00167-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref152">
        <label>152</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hayes</surname>
              <given-names>SC</given-names>
            </name>
            <name name-style="western">
              <surname>Pistorello</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Levin</surname>
              <given-names>ME</given-names>
            </name>
          </person-group>
          <article-title>Acceptance and commitment therapy as a unified model of behavior change</article-title>
          <source>Counsel Psychol</source>
          <year>2012</year>
          <month>09</month>
          <day>26</day>
          <volume>40</volume>
          <issue>7</issue>
          <fpage>976</fpage>
          <lpage>1002</lpage>
          <pub-id pub-id-type="doi">10.1177/0011000012460836</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref153">
        <label>153</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Thompson</surname>
              <given-names>EM</given-names>
            </name>
            <name name-style="western">
              <surname>Destree</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Albertella</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Fontenelle</surname>
              <given-names>LF</given-names>
            </name>
          </person-group>
          <article-title>Internet-based acceptance and commitment therapy: a transdiagnostic systematic review and meta-analysis for mental health outcomes</article-title>
          <source>Behav Ther</source>
          <year>2021</year>
          <month>03</month>
          <volume>52</volume>
          <issue>2</issue>
          <fpage>492</fpage>
          <lpage>507</lpage>
          <pub-id pub-id-type="doi">10.1016/j.beth.2020.07.002</pub-id>
          <pub-id pub-id-type="medline">33622516</pub-id>
          <pub-id pub-id-type="pii">S0005-7894(20)30100-3</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref154">
        <label>154</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wells</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Carter</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <person-group person-group-type="editor">
            <name name-style="western">
              <surname>Carr</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>McNulty</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Generalized anxiety disorder</article-title>
          <source>The Handbook of Adult Clinical Psychology</source>
          <year>2016</year>
          <publisher-loc>Abingdon</publisher-loc>
          <publisher-name>Routledge</publisher-name>
          <fpage>447</fpage>
          <lpage>81</lpage>
        </nlm-citation>
      </ref>
      <ref id="ref155">
        <label>155</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gross</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Thompson</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <person-group person-group-type="editor">
            <name name-style="western">
              <surname>Gross</surname>
              <given-names>JJ</given-names>
            </name>
          </person-group>
          <article-title>Emotion regulation: conceptual foundations</article-title>
          <source>Handbook of Emotion Regulation</source>
          <year>2007</year>
          <publisher-loc>New York</publisher-loc>
          <publisher-name>The Guilford Press</publisher-name>
          <fpage>3</fpage>
          <lpage>24</lpage>
        </nlm-citation>
      </ref>
      <ref id="ref156">
        <label>156</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Peprah</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Argáez</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <source>Dialectical Behavioral Therapy for Adults with Mental Illness: A Review of Clinical Effectiveness and Guidelines</source>
          <year>2017</year>
          <publisher-loc>Ottawa (ON)</publisher-loc>
          <publisher-name>Canadian Agency for Drugs and Technologies in Health</publisher-name>
        </nlm-citation>
      </ref>
      <ref id="ref157">
        <label>157</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Danaher</surname>
              <given-names>BG</given-names>
            </name>
            <name name-style="western">
              <surname>McKay</surname>
              <given-names>HG</given-names>
            </name>
            <name name-style="western">
              <surname>Seeley</surname>
              <given-names>JR</given-names>
            </name>
          </person-group>
          <article-title>The information architecture of behavior change websites</article-title>
          <source>J Med Internet Res</source>
          <year>2005</year>
          <month>05</month>
          <day>18</day>
          <volume>7</volume>
          <issue>2</issue>
          <fpage>e12</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2005/2/e12/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.7.2.e12</pub-id>
          <pub-id pub-id-type="medline">15914459</pub-id>
          <pub-id pub-id-type="pii">v7i2e12</pub-id>
          <pub-id pub-id-type="pmcid">PMC1550648</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref158">
        <label>158</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Pugatch</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Grenen</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Surla</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Schwarz</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Cole-Lewis</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Information architecture of web-based interventions to improve health outcomes: systematic review</article-title>
          <source>J Med Internet Res</source>
          <year>2018</year>
          <month>03</month>
          <day>21</day>
          <volume>20</volume>
          <issue>3</issue>
          <fpage>e97</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2018/3/e97/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.7867</pub-id>
          <pub-id pub-id-type="medline">29563076</pub-id>
          <pub-id pub-id-type="pii">v20i3e97</pub-id>
          <pub-id pub-id-type="pmcid">PMC5978245</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref159">
        <label>159</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Norman</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Webb</surname>
              <given-names>TL</given-names>
            </name>
            <name name-style="western">
              <surname>Millings</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Pechey</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Does the structure (tunneled vs. free-roam) and content (if-then plans vs. choosing strategies) of a brief online alcohol intervention effect engagement and effectiveness? A randomized controlled trial</article-title>
          <source>Transl Behav Med</source>
          <year>2019</year>
          <month>11</month>
          <day>25</day>
          <volume>9</volume>
          <issue>6</issue>
          <fpage>1122</fpage>
          <lpage>30</lpage>
          <pub-id pub-id-type="doi">10.1093/tbm/ibz110</pub-id>
          <pub-id pub-id-type="medline">31287897</pub-id>
          <pub-id pub-id-type="pii">5530258</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref160">
        <label>160</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mohr</surname>
              <given-names>DC</given-names>
            </name>
            <name name-style="western">
              <surname>Burns</surname>
              <given-names>MN</given-names>
            </name>
            <name name-style="western">
              <surname>Schueller</surname>
              <given-names>SM</given-names>
            </name>
            <name name-style="western">
              <surname>Clarke</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Klinkman</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Behavioral intervention technologies: evidence review and recommendations for future research in mental health</article-title>
          <source>Gen Hosp Psychiatry</source>
          <year>2013</year>
          <volume>35</volume>
          <issue>4</issue>
          <fpage>332</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S0163-8343(13)00069-8"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.genhosppsych.2013.03.008</pub-id>
          <pub-id pub-id-type="medline">23664503</pub-id>
          <pub-id pub-id-type="pii">S0163-8343(13)00069-8</pub-id>
          <pub-id pub-id-type="pmcid">PMC3719158</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref161">
        <label>161</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mohr</surname>
              <given-names>DC</given-names>
            </name>
            <name name-style="western">
              <surname>Cuijpers</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Lehman</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Supportive accountability: a model for providing human support to enhance adherence to eHealth interventions</article-title>
          <source>J Med Internet Res</source>
          <year>2011</year>
          <month>03</month>
          <day>10</day>
          <volume>13</volume>
          <issue>1</issue>
          <fpage>e30</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2011/1/e30/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.1602</pub-id>
          <pub-id pub-id-type="medline">21393123</pub-id>
          <pub-id pub-id-type="pii">v13i1e30</pub-id>
          <pub-id pub-id-type="pmcid">PMC3221353</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref162">
        <label>162</label>
        <nlm-citation citation-type="web">
          <article-title>New standards open the door to safe and effective digital mental health care</article-title>
          <source>Australian Commission on Safety and Quality in Healthcare</source>
          <year>2020</year>
          <access-date>2021-12-15</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.safetyandquality.gov.au/publications-and-resources/media-releases/new-standards-open-door-safe-and-effective-digital-mental-health-care">https://www.safetyandquality.gov.au/publications-and-resources/media-releases/new-standards-open-door-safe-and-effective-digital-mental-health-care</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref163">
        <label>163</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Christensen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Griffiths</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>The internet and mental health literacy</article-title>
          <source>Aust N Z J Psychiatry</source>
          <year>2000</year>
          <month>12</month>
          <volume>34</volume>
          <issue>6</issue>
          <fpage>975</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1080/000486700272</pub-id>
          <pub-id pub-id-type="medline">11127628</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
