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<?covid-19-tdm?>
<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="letter" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMH</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Ment Health</journal-id>
      <journal-title>JMIR Mental Health</journal-title>
      <issn pub-type="epub">2368-7959</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v7i7e21718</article-id>
      <article-id pub-id-type="pmid">32668402</article-id>
      <article-id pub-id-type="doi">10.2196/21718</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Commentary</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Commentary</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>An Integrated Blueprint for Digital Mental Health Services Amidst COVID-19</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Derrick</surname>
            <given-names>Thomas</given-names>
          </name>
        </contrib>
        <contrib contrib-type="editor">
          <name>
            <surname>Torous</surname>
            <given-names>John</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Whelan</surname>
            <given-names>Pauline</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Henson</surname>
            <given-names>Philip</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Balcombe</surname>
            <given-names>Luke</given-names>
          </name>
          <degrees>BA, MSc, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Australian Institute for Suicide Research and Prevention</institution>
            <institution>Griffith University</institution>
            <addr-line>Messines Ridge Rd</addr-line>
            <addr-line>Brisbane</addr-line>
            <country>Australia</country>
            <phone>61 447505709</phone>
            <email>lukebalcombe@gmail.com</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6761-3659</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>De Leo</surname>
            <given-names>Diego</given-names>
          </name>
          <degrees>MD, PhD, DSc, FRCPE, FRANZCP</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8255-6480</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Australian Institute for Suicide Research and Prevention</institution>
        <institution>Griffith University</institution>
        <addr-line>Brisbane</addr-line>
        <country>Australia</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Luke Balcombe <email>lukebalcombe@gmail.com</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>7</month>
        <year>2020</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>22</day>
        <month>7</month>
        <year>2020</year>
      </pub-date>
      <volume>7</volume>
      <issue>7</issue>
      <elocation-id>e21718</elocation-id>
      <history>
        <date date-type="received">
          <day>23</day>
          <month>6</month>
          <year>2020</year>
        </date>
        <date date-type="rev-request">
          <day>10</day>
          <month>7</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>13</day>
          <month>7</month>
          <year>2020</year>
        </date>
        <date date-type="accepted">
          <day>14</day>
          <month>7</month>
          <year>2020</year>
        </date>
      </history>
      <copyright-statement>©Luke Balcombe, Diego De Leo. Originally published in JMIR Mental Health (http://mental.jmir.org), 22.07.2020.</copyright-statement>
      <copyright-year>2020</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Mental Health, is properly cited. The complete bibliographic information, a link to the original publication on http://mental.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://mental.jmir.org/2020/7/e21718" xlink:type="simple"/>
      <related-article related-article-type="commentary-article" id="v7i3e18848" ext-link-type="doi" xlink:href="10.2196/18848" vol="7" page="e18848" xlink:type="simple">https://mental.jmir.org/2020/3/e18848/</related-article>
      <related-article related-article-type="commentary-article" id="v7i4e19547" ext-link-type="doi" xlink:href="10.2196/19547" vol="7" page="e19547" xlink:type="simple">https://mental.jmir.org/2020/4/e19547/</related-article>
      <abstract>
        <p>In-person traditional approaches to mental health care services are facing difficulties amidst the coronavirus disease (COVID-19) crisis. The recent implementation of social distancing has redirected attention to nontraditional mental health care delivery to overcome hindrances to essential services. Telehealth has been established for several decades but has only been able to play a small role in health service delivery. Mobile and teledigital health solutions for mental health are well poised to respond to the upsurge in COVID-19 cases. Screening and tracking with real-time automation and machine learning are useful for both assisting psychological first-aid resources and targeting interventions. However, rigorous evaluation of these new opportunities is needed in terms of quality of interventions, effectiveness, and confidentiality. Service delivery could be broadened to include trained, unlicensed professionals, who may help health care services in delivering evidence-based strategies. Digital mental health services emerged during the pandemic as complementary ways of assisting community members with stress and transitioning to new ways of living and working. As part of a hybrid model of care, technologies (mobile and online platforms) require consolidated and consistent guidelines as well as consensus, expert, and position statements on the screening and tracking (with real-time automation and machine learning) of mental health in general populations as well as considerations and initiatives for underserved and vulnerable subpopulations.</p>
      </abstract>
      <kwd-group>
        <kwd>digital mental health</kwd>
        <kwd>mental well-being online assessments</kwd>
        <kwd>machine learning</kwd>
        <kwd>automation</kwd>
        <kwd>COVID-19</kwd>
        <kwd>well-being services</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>It has been proposed that using digital health technology can strengthen our health systems [<xref ref-type="bibr" rid="ref1">1</xref>]. Coupled with high-quality mental health research, digital innovations can aim at resolving “the potential crisis in the provision of health services to helping preserve and reconstruct a post-pandemic society” [<xref ref-type="bibr" rid="ref2">2</xref>]. Digital mental health services delivered online and through smartphone technologies can be useful for targeted psychological interventions in communities affected by coronavirus disease (COVID-19) [<xref ref-type="bibr" rid="ref3">3</xref>]. These provisions may fill the critical gap that practitioners are facing because of higher demand for mental health care services and the limitations of face-to-face consultations [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. In this regard, the COVID-19 crisis could accelerate the use of mobile and teledigital health or at least challenge the usual standard of care [<xref ref-type="bibr" rid="ref6">6</xref>].</p>
    </sec>
    <sec>
      <title>Mental Well-Being Online Assessments and Automated Analysis Via Machine Learning</title>
      <p>Data collection and analysis must be large-scale and of high quality to address mental health needs under the current pandemic. An example of an innovative, tailored, and practical technology applied in research methods is the machine learning induction of models. This technology was applied in a study by Wshah et al [<xref ref-type="bibr" rid="ref7">7</xref>] to predict the probability of posttraumatic stress disorder (PTSD) symptoms in patients 1 month after trauma using self-reported symptoms from data collected via smartphones. The results suggest that simple smartphone-based patient surveys, coupled with automated analysis using machine learning–trained models, can identify those at risk for developing PTSD symptoms, and thus target them for early intervention.</p>
      <p>It has long been acknowledged by mental health practitioners that there is a need to activate all possible opportunities to offer help, including through teleassistance, to patients [<xref ref-type="bibr" rid="ref8">8</xref>]. At-home, mental health treatments are mostly limited to telehealth, where providers remotely communicate with patients over the phone or using video [<xref ref-type="bibr" rid="ref9">9</xref>]. Telemental health services are perfectly suited to pandemic situations, with people being given access to mental health assistance without increasing the risk of contracting infections [<xref ref-type="bibr" rid="ref10">10</xref>]. In times of crisis, the mental health of people needs to be supported in any way possible [<xref ref-type="bibr" rid="ref11">11</xref>]. The call for innovative and expansive solutions and broad-scale collaboration in mental health prevention and intervention delivery includes support for technology [<xref ref-type="bibr" rid="ref12">12</xref>]. Screening for and tracking of stress and adjustment issues in the general population via simple online/smartphone-compatible surveys, coupled with automated real-time analysis using machine learning–trained models, can deliver faster and better mental health care.</p>
    </sec>
    <sec>
      <title>COVID-19 Mental Health Crisis: A Booster for Digital Interventions</title>
      <p>Reliable, valid, and replicable mental health screening and tracking tools via machine learning have the potential to provide an integrated blueprint for the COVID-19 mental health response. The possibility of an integrated offering requires a strategy that brings together different areas of expertise (ie, psychology, psychiatry, emergency and general health care, human welfare, and digital innovation). There is a range of ground-breaking developments happening, with automation taking hold rapidly and consensus to broaden horizons beyond telehealth to deliver digital assets [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>]. A willingness to learn, the capacity to adapt to changes, collaboration, and well-connected management can help to resolve the organizational problems that continue to hamper the large-scale development and implementation of new technologies. The tragic impact of the COVID-19 pandemic may act as a booster for a rapid growth in activities related to digital interventions.</p>
      <p>However, the adoption of digital interventions was recommended well before the onset of the pandemic and suggested as a complementary service that functions alongside traditional treatments, rather than be their replacement [<xref ref-type="bibr" rid="ref15">15</xref>]. An important caveat is the possible lack of access for vulnerable people needing health care [<xref ref-type="bibr" rid="ref1">1</xref>]. The consequences of COVID-19 have emphasized the urgent need to counteract the psychological impact of the pandemic by facilitating access to psychiatric diagnosis and treatment [<xref ref-type="bibr" rid="ref16">16</xref>] while maintaining social distancing.</p>
      <p>Mental health services could be broadened by training unlicensed professionals such as those who work in academia as researchers or in other areas of psychology, psychiatry, or mental health that don’t require direct clinical contact with patients. Self-help interventions can be delivered through a variety of media; these have proven effective for a range of mental health problems [<xref ref-type="bibr" rid="ref17">17</xref>] and could be further explored for whether adjustment to a remote care set-up is linked to a (more) fertile mindset to solve issues.</p>
    </sec>
    <sec>
      <title>Evaluation of Digital Interventions Required for Quality Assurance</title>
      <p>Quality assurance remains problematic for online psychological services in low- and middle-income countries [<xref ref-type="bibr" rid="ref18">18</xref>] and vulnerable populations [<xref ref-type="bibr" rid="ref14">14</xref>]. There are no current systems known to be in place to evaluate digital mental health innovations with respect to underserved populations. International standards on service quality are essential, as are accessibility, sustainability, equity, and ethics [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref19">19</xref>]. Rigorous evaluations are needed to answer questions related to utility, effectiveness, confidentiality, and quality of interventions [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>].</p>
    </sec>
    <sec>
      <title>Conclusion</title>
      <p>The global potential of digital mental health in improving the accessibility and quality of mental health service provision was boosted during the COVID-19 pandemic. A recent paper by Torous et al [<xref ref-type="bibr" rid="ref14">14</xref>] focused on the requirements for increased efforts around safety, evidence, engagement, outcomes, and implementation to increase the scalability of and access to quality digital mental health care and proposed funding, research, policy changes, training, and equity as investments that will yield ongoing returns. In response, Whelan et al [<xref ref-type="bibr" rid="ref4">4</xref>] emphasized the need for ongoing evaluation to ensure national evidence standards, digital training for mental health professionals, and assessment of how digital health innovations can be safely and sustainably embedded in care pathways with reference to the nonadoption, abandonment, scale-up, spread, and sustainability (NASSS) framework [<xref ref-type="bibr" rid="ref22">22</xref>].</p>
      <p>In adopting, scaling up, spreading, and sustaining digital mental health innovations in the midst of the COVID-19 pandemic and on a long-term basis, we recommend coordinating organizational and system framework assessments with evidence-based, online/smartphone-compatible screening and tracking tools deployed with real-time automation by machine learning–trained models. The results should be presented on sustainable, connected, and geocoded digital platforms, which may be supported by unlicensed professionals in order to expand and maintain patient engagement and increase options for prevention and intervention. A patient is thereby presented with recommendations for mental health care services including options for self-care and practitioner-led care with focus on value and capabilities. We also recommend suitably qualified content on mental health to be disseminated and accessed via digital workspaces with dashboards to build efficiency, consistency, and transparency from a single, global location.</p>
      <p>Scalable screening and tracking tools should be implemented in a hybrid model of care combining face-to-face, telehealth, and digital-health approaches. Machine-readable paper copies or non–smartphone-based messaging could be adapted as solutions where there is a lack of access to the technological resources required for engagement in digital mental health services. An added value of digital mental health is that it may be designed for automated thematic and metadata review, traceability for quality assurance, and assignment of responsibility for identified cases of mental ill health. Existing telepsychiatry guidelines (including other relevant digital technologies) should be considered [<xref ref-type="bibr" rid="ref23">23</xref>] for a consistent and consolidated knowledge management strategy for integrated services. Consensus, expert, and position statements are required from psychiatrists, psychologists, and academic researchers on the individual, cultural, and environmental factors that affect the well-being of the patient with suggestions for brief, valid and reliable screening and tracking surveys for the prevention and treatment of mental health symptoms and disorders. A general population version is needed with specifications for vulnerable subpopulations such as children, college students, domestic violence victims, frontline heath care workers, low socioeconomic groups, athletes, people with mental health disorders, and the elderly.</p>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">COVID-19</term>
          <def>
            <p>coronavirus disease</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">NASSS</term>
          <def>
            <p>nonadoption, abandonment, scale-up, spread, and sustainability</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">PTSD</term>
          <def>
            <p>posttraumatic stress disorder</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kola</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Global mental health and COVID-19</article-title>
          <source>The Lancet Psychiatry</source>
          <year>2020</year>
          <month>6</month>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.thelancet.com/pdfs/journals/lanpsy/PIIS2215-0366(20)30235-2.pdf"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/s2215-0366(20)30235-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>da Silva</surname>
              <given-names>AG</given-names>
            </name>
            <name name-style="western">
              <surname>Miranda</surname>
              <given-names>DM</given-names>
            </name>
            <name name-style="western">
              <surname>Diaz</surname>
              <given-names>AP</given-names>
            </name>
            <name name-style="western">
              <surname>Teles</surname>
              <given-names>ALS</given-names>
            </name>
            <name name-style="western">
              <surname>Malloy-Diniz</surname>
              <given-names>LF</given-names>
            </name>
            <name name-style="western">
              <surname>Palha</surname>
              <given-names>AP</given-names>
            </name>
          </person-group>
          <article-title>Mental health: why it still matters in the midst of a pandemic</article-title>
          <source>Braz J Psychiatry</source>
          <year>2020</year>
          <month>06</month>
          <volume>42</volume>
          <issue>3</issue>
          <fpage>229</fpage>
          <lpage>231</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://www.scielo.br/scielo.php?script=sci_arttext&#38;pid=S1516-44462020005008202&#38;lng=en&#38;nrm=iso&#38;tlng=en"/>
          </comment>
          <pub-id pub-id-type="doi">10.1590/1516-4446-2020-0009</pub-id>
          <pub-id pub-id-type="medline">32267344</pub-id>
          <pub-id pub-id-type="pii">S1516-44462020005008202</pub-id>
          <pub-id pub-id-type="pmcid">PMC7236155</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Cullen</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Gulati</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Kelly</surname>
              <given-names>B D</given-names>
            </name>
          </person-group>
          <article-title>Mental health in the COVID-19 pandemic</article-title>
          <source>QJM</source>
          <year>2020</year>
          <month>05</month>
          <day>01</day>
          <volume>113</volume>
          <issue>5</issue>
          <fpage>311</fpage>
          <lpage>312</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32227218"/>
          </comment>
          <pub-id pub-id-type="doi">10.1093/qjmed/hcaa110</pub-id>
          <pub-id pub-id-type="medline">32227218</pub-id>
          <pub-id pub-id-type="pii">5813733</pub-id>
          <pub-id pub-id-type="pmcid">PMC7184387</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Whelan</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Stockton-Powdrell</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Jardine</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Sainsbury</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Comment on "Digital Mental Health and COVID-19: Using Technology Today to Accelerate the Curve on Access and Quality Tomorrow?: A UK Perspective"</article-title>
          <source>JMIR Ment Health</source>
          <year>2020</year>
          <month>04</month>
          <day>27</day>
          <volume>7</volume>
          <issue>4</issue>
          <fpage>e19547</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2020/4/e19547/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/19547</pub-id>
          <pub-id pub-id-type="medline">32330113</pub-id>
          <pub-id pub-id-type="pii">v7i4e19547</pub-id>
          <pub-id pub-id-type="pmcid">PMC7215513</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wind</surname>
              <given-names>TR</given-names>
            </name>
            <name name-style="western">
              <surname>Rijkeboer</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Andersson</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Riper</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>The COVID-19 pandemic: The 'black swan' for mental health care and a turning point for e-health</article-title>
          <source>Internet Interv</source>
          <year>2020</year>
          <month>04</month>
          <volume>20</volume>
          <fpage>100317</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2214-7829(20)30046-4"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.invent.2020.100317</pub-id>
          <pub-id pub-id-type="medline">32289019</pub-id>
          <pub-id pub-id-type="pii">S2214-7829(20)30046-4</pub-id>
          <pub-id pub-id-type="pmcid">PMC7104190</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Torous</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Keshavan</surname>
              <given-names>Matcheri</given-names>
            </name>
          </person-group>
          <article-title>COVID-19, mobile health and serious mental illness</article-title>
          <source>Schizophr Res</source>
          <year>2020</year>
          <month>04</month>
          <volume>218</volume>
          <fpage>36</fpage>
          <lpage>37</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32327314"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.schres.2020.04.013</pub-id>
          <pub-id pub-id-type="medline">32327314</pub-id>
          <pub-id pub-id-type="pii">S0920-9964(20)30220-6</pub-id>
          <pub-id pub-id-type="pmcid">PMC7161497</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wshah</surname>
              <given-names>Safwan</given-names>
            </name>
            <name name-style="western">
              <surname>Skalka</surname>
              <given-names>Christian</given-names>
            </name>
            <name name-style="western">
              <surname>Price</surname>
              <given-names>Matthew</given-names>
            </name>
          </person-group>
          <article-title>Predicting Posttraumatic Stress Disorder Risk: A Machine Learning Approach</article-title>
          <source>JMIR Ment Health</source>
          <year>2019</year>
          <month>07</month>
          <day>22</day>
          <volume>6</volume>
          <issue>7</issue>
          <fpage>e13946</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2019/7/e13946/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/13946</pub-id>
          <pub-id pub-id-type="medline">31333201</pub-id>
          <pub-id pub-id-type="pii">v6i7e13946</pub-id>
          <pub-id pub-id-type="pmcid">PMC6681635</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Krysinska</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>De Leo</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Telecommunication and Suicide Prevention: Hopes and Challenges for the New Century</article-title>
          <source>Omega (Westport)</source>
          <year>2016</year>
          <month>08</month>
          <day>02</day>
          <volume>55</volume>
          <issue>3</issue>
          <fpage>237</fpage>
          <lpage>253</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.2190/OM.55.3.e"/>
          </comment>
          <pub-id pub-id-type="doi">10.2190/om.55.3.e</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Caulfield</surname>
              <given-names>KA</given-names>
            </name>
            <name name-style="western">
              <surname>George</surname>
              <given-names>MS</given-names>
            </name>
          </person-group>
          <article-title>Treating the mental health effects of COVID-19: The need for at-home neurotherapeutics is now</article-title>
          <source>Brain Stimul</source>
          <year>2020</year>
          <month>07</month>
          <volume>13</volume>
          <issue>4</issue>
          <fpage>939</fpage>
          <lpage>940</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S1935-861X(20)30084-X"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.brs.2020.04.005</pub-id>
          <pub-id pub-id-type="medline">32283246</pub-id>
          <pub-id pub-id-type="pii">S1935-861X(20)30084-X</pub-id>
          <pub-id pub-id-type="pmcid">PMC7146679</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zhou</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Snoswell</surname>
              <given-names>Centaine L</given-names>
            </name>
            <name name-style="western">
              <surname>Harding</surname>
              <given-names>Louise E</given-names>
            </name>
            <name name-style="western">
              <surname>Bambling</surname>
              <given-names>Matthew</given-names>
            </name>
            <name name-style="western">
              <surname>Edirippulige</surname>
              <given-names>Sisira</given-names>
            </name>
            <name name-style="western">
              <surname>Bai</surname>
              <given-names>Xuejun</given-names>
            </name>
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>Anthony C</given-names>
            </name>
          </person-group>
          <article-title>The Role of Telehealth in Reducing the Mental Health Burden from COVID-19</article-title>
          <source>Telemed J E Health</source>
          <year>2020</year>
          <month>04</month>
          <volume>26</volume>
          <issue>4</issue>
          <fpage>377</fpage>
          <lpage>379</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1089/tmj.2020.0068"/>
          </comment>
          <pub-id pub-id-type="doi">10.1089/tmj.2020.0068</pub-id>
          <pub-id pub-id-type="medline">32202977</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>De Leo</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Trabucchi</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>The fight against COVID-19: a report from the Italian trenches</article-title>
          <source>Int Psychogeriatr</source>
          <year>2020</year>
          <month>04</month>
          <day>20</day>
          <fpage>1</fpage>
          <lpage>4</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1017/S1041610220000630"/>
          </comment>
          <pub-id pub-id-type="doi">10.1017/s1041610220000630</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rudd</surname>
              <given-names>BN</given-names>
            </name>
            <name name-style="western">
              <surname>Beidas</surname>
              <given-names>RS</given-names>
            </name>
          </person-group>
          <article-title>Digital Mental Health: The Answer to the Global Mental Health Crisis?</article-title>
          <source>JMIR Ment Health</source>
          <year>2020</year>
          <month>06</month>
          <day>02</day>
          <volume>7</volume>
          <issue>6</issue>
          <fpage>e18472</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2020/6/e18472/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/18472</pub-id>
          <pub-id pub-id-type="medline">32484445</pub-id>
          <pub-id pub-id-type="pii">v7i6e18472</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ifdil</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Fadli</surname>
              <given-names>Rima Pratiwi</given-names>
            </name>
            <name name-style="western">
              <surname>Suranata</surname>
              <given-names>Kadek</given-names>
            </name>
            <name name-style="western">
              <surname>Zola</surname>
              <given-names>Nilma</given-names>
            </name>
            <name name-style="western">
              <surname>Ardi</surname>
              <given-names>Zadrian</given-names>
            </name>
          </person-group>
          <article-title>Online mental health services in Indonesia during the COVID-19 outbreak</article-title>
          <source>Asian J Psychiatr</source>
          <year>2020</year>
          <month>05</month>
          <day>05</day>
          <volume>51</volume>
          <fpage>102153</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32403025"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.ajp.2020.102153</pub-id>
          <pub-id pub-id-type="medline">32403025</pub-id>
          <pub-id pub-id-type="pii">S1876-2018(20)30264-1</pub-id>
          <pub-id pub-id-type="pmcid">PMC7199669</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Torous</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Jän Myrick</surname>
              <given-names>Keris</given-names>
            </name>
            <name name-style="western">
              <surname>Rauseo-Ricupero</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Firth</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Digital Mental Health and COVID-19: Using Technology Today to Accelerate the Curve on Access and Quality Tomorrow</article-title>
          <source>JMIR Ment Health</source>
          <year>2020</year>
          <month>03</month>
          <day>26</day>
          <volume>7</volume>
          <issue>3</issue>
          <fpage>e18848</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://mental.jmir.org/2020/3/e18848/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/18848</pub-id>
          <pub-id pub-id-type="medline">32213476</pub-id>
          <pub-id pub-id-type="pii">v7i3e18848</pub-id>
          <pub-id pub-id-type="pmcid">PMC7101061</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Patel</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Saxena</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Frankish</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Boyce</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Sustainable development and global mental health—a Lancet Commission</article-title>
          <source>The Lancet</source>
          <year>2016</year>
          <month>03</month>
          <volume>387</volume>
          <issue>10024</issue>
          <fpage>1143</fpage>
          <lpage>1145</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1016/S0140-6736(16)00208-7"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/s0140-6736(16)00208-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Thome</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Coogan</surname>
              <given-names>Andrew N</given-names>
            </name>
            <name name-style="western">
              <surname>Fischer</surname>
              <given-names>Matthias</given-names>
            </name>
            <name name-style="western">
              <surname>Tucha</surname>
              <given-names>Oliver</given-names>
            </name>
            <name name-style="western">
              <surname>Faltraco</surname>
              <given-names>Frank</given-names>
            </name>
          </person-group>
          <article-title>Challenges for mental health services during the 2020 COVID-19 outbreak in Germany</article-title>
          <source>Psychiatry Clin Neurosci</source>
          <year>2020</year>
          <month>07</month>
          <volume>74</volume>
          <issue>7</issue>
          <fpage>407</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32363760"/>
          </comment>
          <pub-id pub-id-type="doi">10.1111/pcn.13019</pub-id>
          <pub-id pub-id-type="medline">32363760</pub-id>
          <pub-id pub-id-type="pmcid">PMC7267148</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Scott</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Webb</surname>
              <given-names>Thomas L</given-names>
            </name>
            <name name-style="western">
              <surname>Rowse</surname>
              <given-names>Georgina</given-names>
            </name>
          </person-group>
          <article-title>Self-help interventions for psychosis: a meta-analysis</article-title>
          <source>Clin Psychol Rev</source>
          <year>2015</year>
          <month>07</month>
          <volume>39</volume>
          <fpage>96</fpage>
          <lpage>112</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1016/j.cpr.2015.05.002"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.cpr.2015.05.002</pub-id>
          <pub-id pub-id-type="medline">26046501</pub-id>
          <pub-id pub-id-type="pii">S0272-7358(15)00062-8</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Yao</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>Jian-Hua</given-names>
            </name>
            <name name-style="western">
              <surname>Xu</surname>
              <given-names>Yi-Feng</given-names>
            </name>
          </person-group>
          <article-title>Rethinking online mental health services in China during the COVID-19 epidemic</article-title>
          <source>Asian J Psychiatr</source>
          <year>2020</year>
          <month>04</month>
          <volume>50</volume>
          <fpage>102015</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32247261"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.ajp.2020.102015</pub-id>
          <pub-id pub-id-type="medline">32247261</pub-id>
          <pub-id pub-id-type="pii">S1876-2018(20)30126-X</pub-id>
          <pub-id pub-id-type="pmcid">PMC7271098</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Nebeker</surname>
              <given-names>Camille</given-names>
            </name>
            <name name-style="western">
              <surname>Bartlett Ellis</surname>
              <given-names>Rebecca J</given-names>
            </name>
            <name name-style="western">
              <surname>Torous</surname>
              <given-names>John</given-names>
            </name>
          </person-group>
          <article-title>Development of a decision-making checklist tool to support technology selection in digital health research</article-title>
          <source>Transl Behav Med</source>
          <year>2019</year>
          <month>05</month>
          <day>23</day>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1093/tbm/ibz074"/>
          </comment>
          <pub-id pub-id-type="doi">10.1093/tbm/ibz074</pub-id>
          <pub-id pub-id-type="medline">31120511</pub-id>
          <pub-id pub-id-type="pii">5497676</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wisniewski</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Liu</surname>
              <given-names>Gang</given-names>
            </name>
            <name name-style="western">
              <surname>Henson</surname>
              <given-names>Philip</given-names>
            </name>
            <name name-style="western">
              <surname>Vaidyam</surname>
              <given-names>Aditya</given-names>
            </name>
            <name name-style="western">
              <surname>Hajratalli</surname>
              <given-names>Narissa Karima</given-names>
            </name>
            <name name-style="western">
              <surname>Onnela</surname>
              <given-names>Jukka-Pekka</given-names>
            </name>
            <name name-style="western">
              <surname>Torous</surname>
              <given-names>John</given-names>
            </name>
          </person-group>
          <article-title>Understanding the quality, effectiveness and attributes of top-rated smartphone health apps</article-title>
          <source>Evid Based Ment Health</source>
          <year>2019</year>
          <month>02</month>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>4</fpage>
          <lpage>9</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/30635262"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/ebmental-2018-300069</pub-id>
          <pub-id pub-id-type="medline">30635262</pub-id>
          <pub-id pub-id-type="pii">ebmental-2018-300069</pub-id>
          <pub-id pub-id-type="pmcid">PMC7061529</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ransing</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Nagendrappa</surname>
              <given-names>Sachin</given-names>
            </name>
            <name name-style="western">
              <surname>Patil</surname>
              <given-names>Amol</given-names>
            </name>
            <name name-style="western">
              <surname>Shoib</surname>
              <given-names>Sheikh</given-names>
            </name>
            <name name-style="western">
              <surname>Sarkar</surname>
              <given-names>Dipayan</given-names>
            </name>
          </person-group>
          <article-title>Potential role of artificial intelligence to address the COVID-19 outbreak-related mental health issues in India</article-title>
          <source>Psychiatry Res</source>
          <year>2020</year>
          <month>06</month>
          <day>01</day>
          <volume>290</volume>
          <fpage>113176</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1016/j.psychres.2020.113176"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.psychres.2020.113176</pub-id>
          <pub-id pub-id-type="medline">32531628</pub-id>
          <pub-id pub-id-type="pii">S0165-1781(20)31605-X</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Greenhalgh</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Wherton</surname>
              <given-names>Joseph</given-names>
            </name>
            <name name-style="western">
              <surname>Papoutsi</surname>
              <given-names>Chrysanthi</given-names>
            </name>
            <name name-style="western">
              <surname>Lynch</surname>
              <given-names>Jennifer</given-names>
            </name>
            <name name-style="western">
              <surname>Hughes</surname>
              <given-names>Gemma</given-names>
            </name>
            <name name-style="western">
              <surname>A'Court</surname>
              <given-names>Christine</given-names>
            </name>
            <name name-style="western">
              <surname>Hinder</surname>
              <given-names>Susan</given-names>
            </name>
            <name name-style="western">
              <surname>Fahy</surname>
              <given-names>Nick</given-names>
            </name>
            <name name-style="western">
              <surname>Procter</surname>
              <given-names>Rob</given-names>
            </name>
            <name name-style="western">
              <surname>Shaw</surname>
              <given-names>Sara</given-names>
            </name>
          </person-group>
          <article-title>Beyond Adoption: A New Framework for Theorizing and Evaluating Nonadoption, Abandonment, and Challenges to the Scale-Up, Spread, and Sustainability of Health and Care Technologies</article-title>
          <source>J Med Internet Res</source>
          <year>2017</year>
          <month>11</month>
          <day>01</day>
          <volume>19</volume>
          <issue>11</issue>
          <fpage>e367</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.jmir.org/2017/11/e367/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/jmir.8775</pub-id>
          <pub-id pub-id-type="medline">29092808</pub-id>
          <pub-id pub-id-type="pii">v19i11e367</pub-id>
          <pub-id pub-id-type="pmcid">PMC5688245</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Smith</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Ostinelli</surname>
              <given-names>Edoardo</given-names>
            </name>
            <name name-style="western">
              <surname>Macdonald</surname>
              <given-names>Orla</given-names>
            </name>
            <name name-style="western">
              <surname>Cipriani</surname>
              <given-names>Andrea</given-names>
            </name>
          </person-group>
          <article-title>COVID-19 and telepsychiatry: an evidence-based guidance for clinicians</article-title>
          <source>JMIR Ment Health</source>
          <year>2020</year>
          <month>07</month>
          <day>10</day>
          <fpage>a</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.2196/21108"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/21108</pub-id>
          <pub-id pub-id-type="medline">32658857</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
